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The map label for this gene is coaE [H]

Identifier: 145295498

GI number: 145295498

Start: 1569144

End: 1569746

Strand: Direct

Name: coaE [H]

Synonym: cgR_1426

Alternate gene names: 145295498

Gene position: 1569144-1569746 (Clockwise)

Preceding gene: 145295497

Following gene: 145295499

Centisome position: 47.35

GC content: 52.24

Gene sequence:

>603_bases
ATGTTGCGCATTGGATTAACAGGAGGGATCGGCAGCGGTAAATCTACCGTTGCCGATCTTTTGTCATCTGAAGGATTTCT
CATCGTCGACGCGGACCAAGTTGCCCGCGATATCGTCGAACCCGGACAACCGGCATTAGAAGAGCTAGTTGAAGCTTTTG
GCCAAGACATCTTGAAACCCGACGGCACTCTAGACCGCGCGGGATTAGCAGCCAAAGCATTTGTCAGCGAAGAACAAACA
GCGCTGCTCAATGCCATTACCCACCCTCGTATCGCCGAAGAGTCAGCTCGTCGATTCAACGAAGCCGAAGCTCAAGGCGC
CAAAGTCGCGGTTTATGATATGCCTTTGCTTGTAGAAAAAGGCCTTGACCGCAAGATGGACCTTGTCGTCGTAGTTGATG
TTGACGTAGAGGAGCGCGTCCGCAGACTTGTGGAAAAACGTGGCCTCACAGAGGACGACGTGCGGCGTCGAATCGCTTCC
CAGGTGCCCGATGATGTCAGACTTAAAGCCGCTGACATCGTTGTAGACAATAACGGCACGCTAGAGGATCTTCATGCTGA
AGCAAGCAAGCTGATTGCTGAGATTCTTGGTCGCGTGAATTAG

Upstream 100 bases:

>100_bases
GCCGCAAAATTCGGTGAAATTGAAGGTATTCCTGCAGATCAGGCAAATTCTTCCACGACTGTGATCAAGGTCAACGGCAA
GAACGAGTAACCTGGGATCC

Downstream 100 bases:

>100_bases
CACTAAAACATCCTCAAAGTCGATCTACCAGGAAAGTCCTCGGAACAACGCAATTACGTCAGTTCCGAGGGCTTTTTCGT
TTGAGTGCTGGTGATGAACG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MLRIGLTGGIGSGKSTVADLLSSEGFLIVDADQVARDIVEPGQPALEELVEAFGQDILKPDGTLDRAGLAAKAFVSEEQT
ALLNAITHPRIAEESARRFNEAEAQGAKVAVYDMPLLVEKGLDRKMDLVVVVDVDVEERVRRLVEKRGLTEDDVRRRIAS
QVPDDVRLKAADIVVDNNGTLEDLHAEASKLIAEILGRVN

Sequences:

>Translated_200_residues
MLRIGLTGGIGSGKSTVADLLSSEGFLIVDADQVARDIVEPGQPALEELVEAFGQDILKPDGTLDRAGLAAKAFVSEEQT
ALLNAITHPRIAEESARRFNEAEAQGAKVAVYDMPLLVEKGLDRKMDLVVVVDVDVEERVRRLVEKRGLTEDDVRRRIAS
QVPDDVRLKAADIVVDNNGTLEDLHAEASKLIAEILGRVN
>Mature_200_residues
MLRIGLTGGIGSGKSTVADLLSSEGFLIVDADQVARDIVEPGQPALEELVEAFGQDILKPDGTLDRAGLAAKAFVSEEQT
ALLNAITHPRIAEESARRFNEAEAQGAKVAVYDMPLLVEKGLDRKMDLVVVVDVDVEERVRRLVEKRGLTEDDVRRRIAS
QVPDDVRLKAADIVVDNNGTLEDLHAEASKLIAEILGRVN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=37.2222222222222, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=37.2222222222222, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI110227607, Length=182, Percent_Identity=35.1648351648352, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI110227605, Length=182, Percent_Identity=35.1648351648352, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI110227603, Length=182, Percent_Identity=35.1648351648352, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI110227601, Length=182, Percent_Identity=35.1648351648352, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI205277394, Length=182, Percent_Identity=35.1648351648352, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1786292, Length=193, Percent_Identity=38.3419689119171, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=37.0558375634518, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25143409, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=37.5, Blast_Score=122, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24644728, Length=194, Percent_Identity=36.5979381443299, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24658602, Length=189, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21675; Mature: 21675

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIGLTGGIGSGKSTVADLLSSEGFLIVDADQVARDIVEPGQPALEELVEAFGQDILKP
CEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DGTLDRAGLAAKAFVSEEQTALLNAITHPRIAEESARRFNEAEAQGAKVAVYDMPLLVEK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHC
GLDRKMDLVVVVDVDVEERVRRLVEKRGLTEDDVRRRIASQVPDDVRLKAADIVVDNNGT
CCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCC
LEDLHAEASKLIAEILGRVN
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRIGLTGGIGSGKSTVADLLSSEGFLIVDADQVARDIVEPGQPALEELVEAFGQDILKP
CEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DGTLDRAGLAAKAFVSEEQTALLNAITHPRIAEESARRFNEAEAQGAKVAVYDMPLLVEK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHC
GLDRKMDLVVVVDVDVEERVRRLVEKRGLTEDDVRRRIASQVPDDVRLKAADIVVDNNGT
CCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCC
LEDLHAEASKLIAEILGRVN
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]