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The map label for this gene is lysE [H]

Identifier: 145295401

GI number: 145295401

Start: 1471028

End: 1471738

Strand: Reverse

Name: lysE [H]

Synonym: cgR_1339

Alternate gene names: 145295401

Gene position: 1471738-1471028 (Counterclockwise)

Preceding gene: 145295403

Following gene: 145295388

Centisome position: 44.41

GC content: 55.7

Gene sequence:

>711_bases
ATGGTGATCATGGAAATCTTCATTACAGGTCTGCTTTTGGGGGCCAGTCTTTTGCTGTCCATCGGACCGCAGAATGTACT
GGTGATTAAACAAGGAATTAAGCGCGAAGGACTCATTGCGGTTCTTCTCGTGTGTTTAATTTCTGACGTCTTTTTGTTCA
TCGCCGGCACCTTGGGCGTTGATCTTTTGTCCAATGCCGCGCCGATCGTGCTCGATATTATGCGCTGGGGTGGCATCGCT
TACCTGTTATGGTTTGCCGTCATGGCAGCGAAAGACGCCATGACAAACAAGGTGGAAGCGCCACAGATCATTGAAGAAAC
AGAACCAACCGTGCCCGATGACACGCCTTTGGGCGGTTCGGCGGTGGCCACTGACACGCGCAACCGGGTGCGGGTGGAGG
TGAGCGTCGATAAGCAGCGGGTTTGGGTAAAGCCCATGTTGATGGCAATCGTGCTGACCTGGTTGAACCCGAATGCGTAT
TTGGACGCGTTTGTGTTTATCGGCGGCGTCGGCGCGCAATACGGCGACACCGGACGGTGGATTTTCGCCGCTGGCGCGTT
CGCGGCAAGCCTGATCTGGTTCCCGCTGGTGGGTTTCGGCGCAGCAGCATTGTCACGCCCGCTGTCCAGCCCCAAGGTGT
GGCGCTGGATCAACGTCGTCGTGGCAGTTGTGATGACCGCATTGGCCATCAAACTGATGTTGATGGGTTAG

Upstream 100 bases:

>100_bases
AATGATTGAGAGCAAAGTGTCCAGGTGAATGGGGTTCATGAAGCTATATTAAACCATGTTAAGAACCAATCATTTTACTT
AAGTACCTCCATAGGTCACG

Downstream 100 bases:

>100_bases
TTTTCGCGGGTTTTAGAATCGGTGGCCTTCGCCCAAATGTTGATGCCGGCGTCGTGGGAAATCTCATCGATCGCCTCCAA
CTCGGCGTCGGAGAACTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MVIMEIFITGLLLGASLLLSIGPQNVLVIKQGIKREGLIAVLLVCLISDVFLFIAGTLGVDLLSNAAPIVLDIMRWGGIA
YLLWFAVMAAKDAMTNKVEAPQIIEETEPTVPDDTPLGGSAVATDTRNRVRVEVSVDKQRVWVKPMLMAIVLTWLNPNAY
LDAFVFIGGVGAQYGDTGRWIFAAGAFAASLIWFPLVGFGAAALSRPLSSPKVWRWINVVVAVVMTALAIKLMLMG

Sequences:

>Translated_236_residues
MVIMEIFITGLLLGASLLLSIGPQNVLVIKQGIKREGLIAVLLVCLISDVFLFIAGTLGVDLLSNAAPIVLDIMRWGGIA
YLLWFAVMAAKDAMTNKVEAPQIIEETEPTVPDDTPLGGSAVATDTRNRVRVEVSVDKQRVWVKPMLMAIVLTWLNPNAY
LDAFVFIGGVGAQYGDTGRWIFAAGAFAASLIWFPLVGFGAAALSRPLSSPKVWRWINVVVAVVMTALAIKLMLMG
>Mature_236_residues
MVIMEIFITGLLLGASLLLSIGPQNVLVIKQGIKREGLIAVLLVCLISDVFLFIAGTLGVDLLSNAAPIVLDIMRWGGIA
YLLWFAVMAAKDAMTNKVEAPQIIEETEPTVPDDTPLGGSAVATDTRNRVRVEVSVDKQRVWVKPMLMAIVLTWLNPNAY
LDAFVFIGGVGAQYGDTGRWIFAAGAFAASLIWFPLVGFGAAALSRPLSSPKVWRWINVVVAVVMTALAIKLMLMG

Specific function: Involved in the efflux of excess of L-lysine. This is necessary to control the intracellular L-lysine level [H]

COG id: COG1279

COG function: function code R; Lysine efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LysE/ArgO transporter (TC 2.A.75) family [H]

Homologues:

Organism=Escherichia coli, GI1789290, Length=231, Percent_Identity=35.0649350649351, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004777
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 25426; Mature: 25426

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIMEIFITGLLLGASLLLSIGPQNVLVIKQGIKREGLIAVLLVCLISDVFLFIAGTLGV
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLLSNAAPIVLDIMRWGGIAYLLWFAVMAAKDAMTNKVEAPQIIEETEPTVPDDTPLGGS
HHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCC
AVATDTRNRVRVEVSVDKQRVWVKPMLMAIVLTWLNPNAYLDAFVFIGGVGAQYGDTGRW
EEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCE
IFAAGAFAASLIWFPLVGFGAAALSRPLSSPKVWRWINVVVAVVMTALAIKLMLMG
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIMEIFITGLLLGASLLLSIGPQNVLVIKQGIKREGLIAVLLVCLISDVFLFIAGTLGV
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLLSNAAPIVLDIMRWGGIAYLLWFAVMAAKDAMTNKVEAPQIIEETEPTVPDDTPLGGS
HHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCC
AVATDTRNRVRVEVSVDKQRVWVKPMLMAIVLTWLNPNAYLDAFVFIGGVGAQYGDTGRW
EEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCE
IFAAGAFAASLIWFPLVGFGAAALSRPLSSPKVWRWINVVVAVVMTALAIKLMLMG
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8971704; 12948626 [H]