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The map label for this gene is moeA [H]

Identifier: 145295335

GI number: 145295335

Start: 1402765

End: 1403976

Strand: Reverse

Name: moeA [H]

Synonym: cgR_1275

Alternate gene names: 145295335

Gene position: 1403976-1402765 (Counterclockwise)

Preceding gene: 145295336

Following gene: 145295334

Centisome position: 42.36

GC content: 54.29

Gene sequence:

>1212_bases
GTGGCACAGCAACGCAGCGTCGATGACTATCTTTCCATTTTGGTAGACAGCGTCGCACCGCTTCCGCCAGTAAAAACCCC
TATCCTCGGCGCGCATCCGTTAAGTCACCTTGCAGAGGATGTTGTCGCGACAATTCCTATCCCGAAATTTACTAATTCTG
CTGTTGATGGTTACGCCATTTTGAAAGAAGACATCCATGGCAGCGGGCCGTGGACATTTCTTGTGGGCGGTGATACTCCG
GCGGGTTCTGCGCCGGCGAGCATTAATAATGGAAAAGCCATCCGTGTGATGACAGGTGGACCCGTCCCATCCACCAACAA
GGACATGATCGTGGTTCCAGTGGAGCTCACCAATGCTCCGGTGGATCACTCGCTTCCTACAGAAATCACGATCAATGAGC
TACCAGGTGAGAGGAATAATATTCGCCATGCTGGTGAGCATCTTAAAGAAGGCGAAATTGCGGTTGCTGCGGGGACTGCA
TTTGATGCGGGCACTGTGTCGACGGTGATTTCAGTTGGCCATGACACTGTAAAAGCCCATCCTTGCCCTCGGGTTGCGGT
GATCACTACCGGTGATGAGCTAAACCAGGGAAATCCCTGGGGTATCCCTAATTCCAATGGGCCGATGCTGGTTGCGGAGC
TAAAACGCGTGGGGATTAAGGATCCGCAGCATTTCCATTCCGATGACAATGAGGGAGCGCTCGAAGAGACCTTCAATAAG
GCGGCGGAGATTGCTGATGTGATCATCACTGTGGGTGGGATCTCGGCGGGTGCGTTCGATGTGGTCAAAGCCGTGGGAAC
TAAGACTGGTGGTTTTGAGTTCTTCCCCATTGCGATGAAGCCGGGTAAACCGCAAGGTCATGGGCAATGGGGCGACGCAA
AAGTGGTGTGTCTGCCGGGAAACCCGGTGGCGGCGTGGGTTAGTTTTAGGCTCTTTGTTGTTCCGGTAATTGAGAGATTA
GGGGGTGGAAAGAGGGTGGCGTCGATAAGCGAACTCCCTGTGGTGGCGCTGCGCTCGAACCGGGCGCTGAAGGAGCGGGA
GGGCACTGTGGTGGCGATTCCGGTGGCGATTGATTGGGAGAAAAGAATGGCAAATTCTCAGGCACATCGATCCCATATGG
TCGGTGCGCTGGCTGGAAGTGGCGGTATTGCACTGGTGACTTCGTCGATTGCCGAGGACGGTCTGGTTGATGTTGTGCTG
GGGAGAATGTAA

Upstream 100 bases:

>100_bases
ACACCCGTTTGAGAATCTCAACCTCTTAAAACAGCGCAGACTATTGATTTGGCAACTACCCTATATATTTGAGTGTTTAT
TGTCGAAAAAGGGGTTTCAA

Downstream 100 bases:

>100_bases
ATGAATATCATCATTCTTGCTGGTGGCAAGGGTAAACGCATGGGTGGGGTGGATAAGGCTGCAGTGGCGGTGGATGGTCG
CACGCTGCTGGATATCCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAQQRSVDDYLSILVDSVAPLPPVKTPILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAILKEDIHGSGPWTFLVGGDTP
AGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAPVDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTA
FDAGTVSTVISVGHDTVKAHPCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDNEGALEETFNK
AAEIADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPGNPVAAWVSFRLFVVPVIERL
GGGKRVASISELPVVALRSNRALKEREGTVVAIPVAIDWEKRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVL
GRM

Sequences:

>Translated_403_residues
MAQQRSVDDYLSILVDSVAPLPPVKTPILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAILKEDIHGSGPWTFLVGGDTP
AGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAPVDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTA
FDAGTVSTVISVGHDTVKAHPCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDNEGALEETFNK
AAEIADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPGNPVAAWVSFRLFVVPVIERL
GGGKRVASISELPVVALRSNRALKEREGTVVAIPVAIDWEKRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVL
GRM
>Mature_402_residues
AQQRSVDDYLSILVDSVAPLPPVKTPILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAILKEDIHGSGPWTFLVGGDTPA
GSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAPVDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTAF
DAGTVSTVISVGHDTVKAHPCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDNEGALEETFNKA
AEIADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPGNPVAAWVSFRLFVVPVIERLG
GGKRVASISELPVVALRSNRALKEREGTVVAIPVAIDWEKRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVLG
RM

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=318, Percent_Identity=32.7044025157233, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI10880983, Length=318, Percent_Identity=32.7044025157233, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1787049, Length=326, Percent_Identity=32.5153374233129, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25147659, Length=302, Percent_Identity=29.1390728476821, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562606, Length=370, Percent_Identity=26.7567567567568, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136978, Length=323, Percent_Identity=29.1021671826625, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638841, Length=323, Percent_Identity=29.1021671826625, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 42086; Mature: 41954

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQQRSVDDYLSILVDSVAPLPPVKTPILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAI
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCEE
LKEDIHGSGPWTFLVGGDTPAGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAP
EHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
VDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTAFDAGTVSTVISVGHDTVKAH
CCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCEECC
PCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDNEGALEETFNK
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHCCCCCCCHHHHHHHH
AAEIADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPG
HHHHHEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECC
NPVAAWVSFRLFVVPVIERLGGGKRVASISELPVVALRSNRALKEREGTVVAIPVAIDWE
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCHHHHCCCEEEEEEEECHH
KRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVLGRM
HHHCCHHHHHHHHEEEEECCCCEEEEEHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
AQQRSVDDYLSILVDSVAPLPPVKTPILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAI
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCEE
LKEDIHGSGPWTFLVGGDTPAGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAP
EHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
VDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTAFDAGTVSTVISVGHDTVKAH
CCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCEECC
PCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDNEGALEETFNK
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHCCCCCCCHHHHHHHH
AAEIADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPG
HHHHHEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECC
NPVAAWVSFRLFVVPVIERLGGGKRVASISELPVVALRSNRALKEREGTVVAIPVAIDWE
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCHHHHCCCEEEEEEEECHH
KRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVLGRM
HHHCCHHHHHHHHEEEEECCCCEEEEEHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]