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The map label for this gene is argS [H]

Identifier: 145295319

GI number: 145295319

Start: 1380919

End: 1382571

Strand: Direct

Name: argS [H]

Synonym: cgR_1259

Alternate gene names: 145295319

Gene position: 1380919-1382571 (Clockwise)

Preceding gene: 145295317

Following gene: 145295320

Centisome position: 41.67

GC content: 57.17

Gene sequence:

>1653_bases
ATGACACCAGCTGATCTCGCAACATTGATTAAAGAGACCGCGGTAGAGGTTTTGACCTCCCGCGAGCTCGATACTTCTGT
TCTTCCGGAGCAGGTAGTTGTGGAGCGTCCGCGTAACCCAGAGCACGGCGATTACGCCACCAACATTGCATTGCAGGTGG
CTAAAAAGGTCGGTCAGAACCCTCGGGATTTGGCTACCTGGCTGGCAGAGGCATTGGCTGCAGATGACGCCATTGATTCT
GCTGAAATCGCTGGCCCAGGCTTTTTGAACATTCGCCTTGCTGCAGCAGCACAGGGTGAAATTGTGGCCAAGATTCTGGC
ACAGGGCGAGACTTTCGGAAACTCCGATCACCTTTCCCACTTGGACGTGAACCTCGAGTTCGTTTCTGCAAACCCAACCG
GACCTATCCACCTTGGCGGAACCCGCTGGGCTGCCGTGGGTGACTCTTTGGGTCGTGTGCTGGAGGCTTCCGGCGCGAAA
GTGACCCGCGAATACTACTTCAACGATCACGGCCGCCAGATCGATCGTTTCGCTTTGTCCCTTCTTGCAGCGGCGAAGGG
CGAGCCAACGCCAGAAGACGGTTATGGCGGCGAATACATTAAGGAAATTGCGGAGGCAATCGTCGAAAAGCATCCTGAAG
CGTTGGCTTTGGAGCCTGCCGCAACCCAGGAGCTTTTCCGCGCTGAAGGCGTGGAGATGATGTTCGAGCACATCAAATCT
TCCCTGCATGAGTTCGGCACCGATTTCGATGTCTACTACCACGAGAACTCCCTGTTCGAGTCCGGTGCGGTGGATAAGGC
CGTGCAGGTGCTGAAGGACAACGGCAACCTGTACGAAAACGAGGGCGCTTGGTGGCTGCGTTCCACCGAATTCGGCGATG
ACAAAGACCGCGTGGTGATCAAGTCTGACGGCGACGCAGCCTACATCGCTGGCGATATCGCGTACGTGGCTGATAAGTTC
TCCCGAGGACACAACCTCAACATCTACATGCTGGGTGCTGACCACCATGGTTACATCGCGCGCCTGAAGGCAGCGGCGGC
GGCACTTGGCTACAAGCCAGAAGGCGTTGAAGTCCTGATTGGCCAGATGGTGAACCTGCTTCGCGACGGCAAGGCAGTGC
GTATGTCCAAGCGTGCAGGCACCGTGGTCACCCTAGATGACCTCGTTGAAGCAATCGGCATCGATGCGGCGCGTTACTCC
CTGATCCGTTCCTCCGTGGATTCCTCCCTGGATATTGATCTCGGCCTGTGGGAATCTCAGTCCTCCGACAACCCTGTGTA
CTACGTGCAGTACGGACACGCTCGCCTTTGCTCCATCGCGCGCAAGGCAGAGACCTTGGGTGTCACCGAGGAAGGCGCAG
ACCTATCTCTACTGACCCACGACCGCGAAGGCGATCTCATCCGCACACTCGGAGAGTTCCCAGCAGTGGTGAAGGCTGCC
GCTGACCTACGTGAACCACACCGCATTGCCCGCTATGCTGAGGAATTAGCTGGAACTTTCCACCGCTTCTACGATTCCTG
CCACATCCTTCCAAAGGCTGATGAGGATACGGCACCAATCCACTCAGCACGTCTGGCACTTGCAGCAGCAACCCGCCAGA
CCCTCGCTAACGCCCTGCACCTGGTTGGCGTTTCCGCACCGGAGAAGATGTAA

Upstream 100 bases:

>100_bases
TATACAGAGACCAATGATTTTTCATTAAAAAGGCAGGGATTTGTTATAAGTATGGGTCGTATTCTGTGCGACGGGTGTAC
CTCGGCTAGAATTTCTCCCC

Downstream 100 bases:

>100_bases
CAATGGCTACAGTTGAAAATTTCAATGAACTTCCCGCACACGTGTGGCCCCGCAATGCCGTGCGCCAAGAAGACGGCGTT
GTCACCGTTGCTGGTGTGCC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTPADLATLIKETAVEVLTSRELDTSVLPEQVVVERPRNPEHGDYATNIALQVAKKVGQNPRDLATWLAEALAADDAIDS
AEIAGPGFLNIRLAAAAQGEIVAKILAQGETFGNSDHLSHLDVNLEFVSANPTGPIHLGGTRWAAVGDSLGRVLEASGAK
VTREYYFNDHGRQIDRFALSLLAAAKGEPTPEDGYGGEYIKEIAEAIVEKHPEALALEPAATQELFRAEGVEMMFEHIKS
SLHEFGTDFDVYYHENSLFESGAVDKAVQVLKDNGNLYENEGAWWLRSTEFGDDKDRVVIKSDGDAAYIAGDIAYVADKF
SRGHNLNIYMLGADHHGYIARLKAAAAALGYKPEGVEVLIGQMVNLLRDGKAVRMSKRAGTVVTLDDLVEAIGIDAARYS
LIRSSVDSSLDIDLGLWESQSSDNPVYYVQYGHARLCSIARKAETLGVTEEGADLSLLTHDREGDLIRTLGEFPAVVKAA
ADLREPHRIARYAEELAGTFHRFYDSCHILPKADEDTAPIHSARLALAAATRQTLANALHLVGVSAPEKM

Sequences:

>Translated_550_residues
MTPADLATLIKETAVEVLTSRELDTSVLPEQVVVERPRNPEHGDYATNIALQVAKKVGQNPRDLATWLAEALAADDAIDS
AEIAGPGFLNIRLAAAAQGEIVAKILAQGETFGNSDHLSHLDVNLEFVSANPTGPIHLGGTRWAAVGDSLGRVLEASGAK
VTREYYFNDHGRQIDRFALSLLAAAKGEPTPEDGYGGEYIKEIAEAIVEKHPEALALEPAATQELFRAEGVEMMFEHIKS
SLHEFGTDFDVYYHENSLFESGAVDKAVQVLKDNGNLYENEGAWWLRSTEFGDDKDRVVIKSDGDAAYIAGDIAYVADKF
SRGHNLNIYMLGADHHGYIARLKAAAAALGYKPEGVEVLIGQMVNLLRDGKAVRMSKRAGTVVTLDDLVEAIGIDAARYS
LIRSSVDSSLDIDLGLWESQSSDNPVYYVQYGHARLCSIARKAETLGVTEEGADLSLLTHDREGDLIRTLGEFPAVVKAA
ADLREPHRIARYAEELAGTFHRFYDSCHILPKADEDTAPIHSARLALAAATRQTLANALHLVGVSAPEKM
>Mature_549_residues
TPADLATLIKETAVEVLTSRELDTSVLPEQVVVERPRNPEHGDYATNIALQVAKKVGQNPRDLATWLAEALAADDAIDSA
EIAGPGFLNIRLAAAAQGEIVAKILAQGETFGNSDHLSHLDVNLEFVSANPTGPIHLGGTRWAAVGDSLGRVLEASGAKV
TREYYFNDHGRQIDRFALSLLAAAKGEPTPEDGYGGEYIKEIAEAIVEKHPEALALEPAATQELFRAEGVEMMFEHIKSS
LHEFGTDFDVYYHENSLFESGAVDKAVQVLKDNGNLYENEGAWWLRSTEFGDDKDRVVIKSDGDAAYIAGDIAYVADKFS
RGHNLNIYMLGADHHGYIARLKAAAAALGYKPEGVEVLIGQMVNLLRDGKAVRMSKRAGTVVTLDDLVEAIGIDAARYSL
IRSSVDSSLDIDLGLWESQSSDNPVYYVQYGHARLCSIARKAETLGVTEEGADLSLLTHDREGDLIRTLGEFPAVVKAAA
DLREPHRIARYAEELAGTFHRFYDSCHILPKADEDTAPIHSARLALAAATRQTLANALHLVGVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788184, Length=568, Percent_Identity=26.7605633802817, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6320548, Length=552, Percent_Identity=26.4492753623188, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6321883, Length=548, Percent_Identity=23.3576642335766, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 59681; Mature: 59550

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPADLATLIKETAVEVLTSRELDTSVLPEQVVVERPRNPEHGDYATNIALQVAKKVGQN
CCHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
PRDLATWLAEALAADDAIDSAEIAGPGFLNIRLAAAAQGEIVAKILAQGETFGNSDHLSH
HHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCEE
LDVNLEFVSANPTGPIHLGGTRWAAVGDSLGRVLEASGAKVTREYYFNDHGRQIDRFALS
EEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEHHHEECCCCCHHHHHHHH
LLAAAKGEPTPEDGYGGEYIKEIAEAIVEKHPEALALEPAATQELFRAEGVEMMFEHIKS
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCCHHHHHHHHHH
SLHEFGTDFDVYYHENSLFESGAVDKAVQVLKDNGNLYENEGAWWLRSTEFGDDKDRVVI
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCEEEE
KSDGDAAYIAGDIAYVADKFSRGHNLNIYMLGADHHGYIARLKAAAAALGYKPEGVEVLI
ECCCCEEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHH
GQMVNLLRDGKAVRMSKRAGTVVTLDDLVEAIGIDAARYSLIRSSVDSSLDIDLGLWESQ
HHHHHHHHCCCCEEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCC
SSDNPVYYVQYGHARLCSIARKAETLGVTEEGADLSLLTHDREGDLIRTLGEFPAVVKAA
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ADLREPHRIARYAEELAGTFHRFYDSCHILPKADEDTAPIHSARLALAAATRQTLANALH
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVGVSAPEKM
HHCCCCCCCC
>Mature Secondary Structure 
TPADLATLIKETAVEVLTSRELDTSVLPEQVVVERPRNPEHGDYATNIALQVAKKVGQN
CHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
PRDLATWLAEALAADDAIDSAEIAGPGFLNIRLAAAAQGEIVAKILAQGETFGNSDHLSH
HHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCEE
LDVNLEFVSANPTGPIHLGGTRWAAVGDSLGRVLEASGAKVTREYYFNDHGRQIDRFALS
EEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEHHHEECCCCCHHHHHHHH
LLAAAKGEPTPEDGYGGEYIKEIAEAIVEKHPEALALEPAATQELFRAEGVEMMFEHIKS
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCCHHHHHHHHHH
SLHEFGTDFDVYYHENSLFESGAVDKAVQVLKDNGNLYENEGAWWLRSTEFGDDKDRVVI
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCEEEE
KSDGDAAYIAGDIAYVADKFSRGHNLNIYMLGADHHGYIARLKAAAAALGYKPEGVEVLI
ECCCCEEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHH
GQMVNLLRDGKAVRMSKRAGTVVTLDDLVEAIGIDAARYSLIRSSVDSSLDIDLGLWESQ
HHHHHHHHCCCCEEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCC
SSDNPVYYVQYGHARLCSIARKAETLGVTEEGADLSLLTHDREGDLIRTLGEFPAVVKAA
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ADLREPHRIARYAEELAGTFHRFYDSCHILPKADEDTAPIHSARLALAAATRQTLANALH
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVGVSAPEKM
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]