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The map label for this gene is ycgO [H]

Identifier: 145295305

GI number: 145295305

Start: 1360629

End: 1362203

Strand: Reverse

Name: ycgO [H]

Synonym: cgR_1245

Alternate gene names: 145295305

Gene position: 1362203-1360629 (Counterclockwise)

Preceding gene: 145295313

Following gene: 145295304

Centisome position: 41.1

GC content: 50.73

Gene sequence:

>1575_bases
ATGAGTGATAACACATGGTTCATCATAGCCATCGTCATCTACATGTTGGTCATGGTGCTCATCGGCTATTGGAGTTACCG
CAAGACAGAAAAATACGACGACTACATGCTCGCCGGCCGCGGGCTCAACCCTTTTGTTGCCGCAATGTCCGCAGGTGCCT
CAGATATGTCAGGTTGGCTGCTCATGGGTCTGCCCGGTGCGCTGTTTGTCACCGGCATGTCCGAGTTGTGGATCGCAGTC
GGACTCACCATTGGTGCATGGGCGAACTGGATGTGGGTGGCACCTCGTCTTCGTTCTTATTCCGAAATCTCGGCCAACTC
AATCACCCTGCCTTCATTCTTTGAGAACCGACTTCGCGATAAATCTCGCGCGCTTCGCATCGTTGCAGCACTAATTATCA
TTGTGTTCTTCACCTTCTACATTTCTTCAGGCATGGTTGCTGGTGGAGTGTATTGGGAGTCCACGTTTGGTGGAGATTAT
CTACTCGGTATGGCCATTGTCGCAGGTGTGACAGTGTTGTATACCTTCATTGGAGGATTCCTTGCTGTGTCTTATACAGA
CGCAGTTCAGGGGACTATCATGTTCTTCTCGTTGATCATCGTGCCAGTCCTGGCATATTTCGCACTAGCGAACCCCATGG
ATATTTGGAGCTTTGCAAGCTCTAATGATTACGGCCCGCACACCGATGGAATTGGCAATCCCACCTACTTCTCCATGATC
AGTGGCATTTCTGCAGCAGCAATCATTGGTAACTTAGGTTGGGGTCTTGGATACTTCGGCCAGCCACACATTGTGGTTCG
TTTCATGGCACTTCGCACACCAGCTGAAGCAAAGCAAGGTCGTCGCATCGGTATTTCCTGGATGATAATCTGCCTGATTG
GTGCAACCTTTACCGCAATTATCTCCACAGTTTTCTTTGCACAAAACCCCGACGCCAACATCACTGACACAAGGGCTTAT
GAGTCCATCTTCCTAGATCTTGCCCGGATGCTGTTCCACCCATTGATCGCTGGACTTATTCTGACTGCTGTTCTCGCGGC
CATCATGTCTACCATGTCGTCACAGCTGCTGGTCACCGCATCTTCCCTGATTGAGGACCTGCTGAAGGTAGTTAAAAAGG
ACTCGCTGAGCGAACGCACCCTGATCATGCTGTCTCGTGCCACAGTCATCATTCTGGCGATCATTGCAGCAGCCATGGCT
ATTAACCCGTCTGATTCCATCCTCGGATTGGTGGGATTTGCGTGGGCAGGATTCGGCTCTGCATTTGGTCCGATCATACT
TGCTAGCCTTTATTGGAAGCGCCTCAACGCCGCCGGCGCTATCTCCGGCATGATTACTGGTGCTATTGCCTCCATCGCGT
GGGGTATGTCCCCACTAAGCGATACGTTGTATGAAATCATCCCAGGTTTCGCCTTGGCAACCATCGTGATGGTCGTTGTT
TCCCTCCTGACAAAGGAACCCTCCGAAGAAATCCTCAACGAGTTTGAAACCGCCAAGGATCTTGCTGCCGCTGTGGAATC
AAACGAGGATGTTGATTTCGCTGACGCAGCTAAGAAGCTTTCGAAAGAAAGTTAA

Upstream 100 bases:

>100_bases
GTATATTCAGACACCCACGTCGATTAGTGTTGTAGTTCACAGTGCTTATTTTTTATTTGTATCTTTGCACGTTTGTCCCC
TACCCAAAAGGAGAAACCTC

Downstream 100 bases:

>100_bases
GCCTTAGAGGGAACCAAACGCCAAGGTGATGAGTCTAACCCGAGTATGAAGAACTTTATTCGGGTACTCATCGCCTTTAG
TGTTTTCCTCTGTATATATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MSDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWLLMGLPGALFVTGMSELWIAV
GLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRDKSRALRIVAALIIIVFFTFYISSGMVAGGVYWESTFGGDY
LLGMAIVAGVTVLYTFIGGFLAVSYTDAVQGTIMFFSLIIVPVLAYFALANPMDIWSFASSNDYGPHTDGIGNPTYFSMI
SGISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGATFTAIISTVFFAQNPDANITDTRAY
ESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVTASSLIEDLLKVVKKDSLSERTLIMLSRATVIILAIIAAAMA
INPSDSILGLVGFAWAGFGSAFGPIILASLYWKRLNAAGAISGMITGAIASIAWGMSPLSDTLYEIIPGFALATIVMVVV
SLLTKEPSEEILNEFETAKDLAAAVESNEDVDFADAAKKLSKES

Sequences:

>Translated_524_residues
MSDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWLLMGLPGALFVTGMSELWIAV
GLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRDKSRALRIVAALIIIVFFTFYISSGMVAGGVYWESTFGGDY
LLGMAIVAGVTVLYTFIGGFLAVSYTDAVQGTIMFFSLIIVPVLAYFALANPMDIWSFASSNDYGPHTDGIGNPTYFSMI
SGISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGATFTAIISTVFFAQNPDANITDTRAY
ESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVTASSLIEDLLKVVKKDSLSERTLIMLSRATVIILAIIAAAMA
INPSDSILGLVGFAWAGFGSAFGPIILASLYWKRLNAAGAISGMITGAIASIAWGMSPLSDTLYEIIPGFALATIVMVVV
SLLTKEPSEEILNEFETAKDLAAAVESNEDVDFADAAKKLSKES
>Mature_523_residues
SDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWLLMGLPGALFVTGMSELWIAVG
LTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRDKSRALRIVAALIIIVFFTFYISSGMVAGGVYWESTFGGDYL
LGMAIVAGVTVLYTFIGGFLAVSYTDAVQGTIMFFSLIIVPVLAYFALANPMDIWSFASSNDYGPHTDGIGNPTYFSMIS
GISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGATFTAIISTVFFAQNPDANITDTRAYE
SIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVTASSLIEDLLKVVKKDSLSERTLIMLSRATVIILAIIAAAMAI
NPSDSILGLVGFAWAGFGSAFGPIILASLYWKRLNAAGAISGMITGAIASIAWGMSPLSDTLYEIIPGFALATIVMVVVS
LLTKEPSEEILNEFETAKDLAAAVESNEDVDFADAAKKLSKES

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=504, Percent_Identity=45.8333333333333, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI109659836, Length=565, Percent_Identity=23.716814159292, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI109659839, Length=583, Percent_Identity=22.9845626072041, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4507035, Length=408, Percent_Identity=23.0392156862745, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI4507031, Length=578, Percent_Identity=22.6643598615917, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI110835708, Length=592, Percent_Identity=22.1283783783784, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI14140236, Length=585, Percent_Identity=23.7606837606838, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787251, Length=500, Percent_Identity=46.8, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1790503, Length=454, Percent_Identity=24.6696035242291, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082237, Length=460, Percent_Identity=26.304347826087, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17539284, Length=469, Percent_Identity=25.5863539445629, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221459584, Length=390, Percent_Identity=23.8461538461538, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640370, Length=350, Percent_Identity=22.5714285714286, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 56561; Mature: 56430

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWL
CCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHCCCCCCCCEE
LMGLPGALFVTGMSELWIAVGLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRD
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHCCCCCCCCHHHHHHHHHH
KSRALRIVAALIIIVFFTFYISSGMVAGGVYWESTFGGDYLLGMAIVAGVTVLYTFIGGF
HHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LAVSYTDAVQGTIMFFSLIIVPVLAYFALANPMDIWSFASSNDYGPHTDGIGNPTYFSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHH
SGISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGATFTAI
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
ISTVFFAQNPDANITDTRAYESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVTA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLIEDLLKVVKKDSLSERTLIMLSRATVIILAIIAAAMAINPSDSILGLVGFAWAGFGS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCH
AFGPIILASLYWKRLNAAGAISGMITGAIASIAWGMSPLSDTLYEIIPGFALATIVMVVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHH
SLLTKEPSEEILNEFETAKDLAAAVESNEDVDFADAAKKLSKES
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWL
CCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHCCCCCCCCEE
LMGLPGALFVTGMSELWIAVGLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRD
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHCCCCCCCCHHHHHHHHHH
KSRALRIVAALIIIVFFTFYISSGMVAGGVYWESTFGGDYLLGMAIVAGVTVLYTFIGGF
HHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LAVSYTDAVQGTIMFFSLIIVPVLAYFALANPMDIWSFASSNDYGPHTDGIGNPTYFSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHH
SGISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGATFTAI
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
ISTVFFAQNPDANITDTRAYESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVTA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLIEDLLKVVKKDSLSERTLIMLSRATVIILAIIAAAMAINPSDSILGLVGFAWAGFGS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCH
AFGPIILASLYWKRLNAAGAISGMITGAIASIAWGMSPLSDTLYEIIPGFALATIVMVVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHH
SLLTKEPSEEILNEFETAKDLAAAVESNEDVDFADAAKKLSKES
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]