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The map label for this gene is engD [H]

Identifier: 145295173

GI number: 145295173

Start: 1226921

End: 1228006

Strand: Direct

Name: engD [H]

Synonym: cgR_1115

Alternate gene names: 145295173

Gene position: 1226921-1228006 (Clockwise)

Preceding gene: 145295167

Following gene: 145295175

Centisome position: 37.02

GC content: 57.46

Gene sequence:

>1086_bases
GTGACCCTTACTCTTGGAATCGTCGGCCTGCCCAACGTTGGCAAGTCCACCCTGTTCAACGCCCTGACCCGCAATGACGT
GCTCGCAGCGAACTACCCGTTCGCTACCATCGAGCCAAACGTGGGCCTCGTCGAGCTTCCAGACGCTCGCCTTGGACGCC
TTTCTGAAATCTTCGGCTCTGAGCGCATCCTGCCAGCAACCGTGTCCTTCGTTGACATCGCCGGAATCGTTAAGGGAGCT
TCCGAAGGCGAAGGAATGGGTAACGCCTTCCTCGCTAACATCCGTGAAGCAGACGCAATCTGCCAGGTTGTCCGAGCATT
CGCTGACGAAAACGTCATCCACGTCGACGGCGAAGTCAACCCAGCAACAGACATCTCCGTGATCAACACCGAGCTGATCC
TCGCTGACCTGCAGACCGTAGAAAAGGCACTGCCTCGCCTCGAGAAGGATGCCCGCAAGGACAAGGCTCTCGGTGAAGTC
CTCGACGAGACCAAGAAGGCTCTCGAGATCCTTAGCGACGACCGCACCTTGTTCTCTGCAGAAAAGGCCGGCGAAATTGA
CCTGGCACTGCTCCGCGACCTTCACCTGATGACTGCGAAGCCTTTCCTCTACGTCTTCAACTCTGACGAAGAAGTGCTCA
CCGACGACGCCAAGAAGGACGAGCTGCGCGCACTCGTTGCACCAGCAGACTGCGTATTCCTCGACGCCCAGACCGAAACT
GAGCTTCTGGAACTCGAAGCCGACGAAGCAGCAGAACTCCTCGAAGCAGTAGGCCAAACCGAACCAGGCCTACACTCCCT
CGCACGTGCAGGATTTGAAACCCTCGGACTGCAGACCTACCTCACCGCAGGTCCTAAGGAATCACGCGCCTGGACCATCC
ACAAGGGTGACACCGCTCCACAGGCAGCAGGTGTTATCCATTCTGACTTCGAACGCGGCTTCATCAAGGCTGAAATCGTC
TCCTTCGAAGACCTCGACGCCGCTGGTTCCATGGCAGAAGCCAAGGCCCAGGGTAAAGTCCGCCAAGAAGGCAAGGACTA
CGTGATGGTTGATGGCGACGTTGTGGAGTTCAAGTTCAACGTGTGA

Upstream 100 bases:

>100_bases
AAGCGAAATTTCACCTTTTTGGAGGCAGTCGACAATGCTCTGGGCACTTTTTGTGCCTCCTGATTAGGTTCTTACCCAAC
GATTGCTAGGATATGTGCCT

Downstream 100 bases:

>100_bases
CGGGCGCAGAAGAGTGGTCAGTCGCGGGGGACGCCAGTCGCTCGAGTGATCACTGCGTCGAACTGGCGATCAGTGAGGAT
GTTGCGCGCGGCAATCAGCG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLGRLSEIFGSERILPATVSFVDIAGIVKGA
SEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVNPATDISVINTELILADLQTVEKALPRLEKDARKDKALGEV
LDETKKALEILSDDRTLFSAEKAGEIDLALLRDLHLMTAKPFLYVFNSDEEVLTDDAKKDELRALVAPADCVFLDAQTET
ELLELEADEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAPQAAGVIHSDFERGFIKAEIV
SFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFKFNV

Sequences:

>Translated_361_residues
MTLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLGRLSEIFGSERILPATVSFVDIAGIVKGA
SEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVNPATDISVINTELILADLQTVEKALPRLEKDARKDKALGEV
LDETKKALEILSDDRTLFSAEKAGEIDLALLRDLHLMTAKPFLYVFNSDEEVLTDDAKKDELRALVAPADCVFLDAQTET
ELLELEADEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAPQAAGVIHSDFERGFIKAEIV
SFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFKFNV
>Mature_360_residues
TLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLGRLSEIFGSERILPATVSFVDIAGIVKGAS
EGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVNPATDISVINTELILADLQTVEKALPRLEKDARKDKALGEVL
DETKKALEILSDDRTLFSAEKAGEIDLALLRDLHLMTAKPFLYVFNSDEEVLTDDAKKDELRALVAPADCVFLDAQTETE
LLELEADEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAPQAAGVIHSDFERGFIKAEIVS
FEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFKFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=373, Percent_Identity=40.4825737265416, Blast_Score=268, Evalue=4e-72,
Organism=Homo sapiens, GI58761502, Length=185, Percent_Identity=40.5405405405405, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1787454, Length=368, Percent_Identity=51.9021739130435, Blast_Score=350, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17509631, Length=370, Percent_Identity=39.4594594594595, Blast_Score=257, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=39.8395721925134, Blast_Score=239, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=34.4647519582245, Blast_Score=209, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=42.4731182795699, Blast_Score=280, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=42.4731182795699, Blast_Score=280, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=42.4731182795699, Blast_Score=280, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24640879, Length=330, Percent_Identity=40.6060606060606, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24585318, Length=141, Percent_Identity=31.2056737588652, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38956; Mature: 38825

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLGRLSEIFGS
CEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCCHHHHHHHHHHCC
ERILPATVSFVDIAGIVKGASEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVN
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PATDISVINTELILADLQTVEKALPRLEKDARKDKALGEVLDETKKALEILSDDRTLFSA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
EKAGEIDLALLRDLHLMTAKPFLYVFNSDEEVLTDDAKKDELRALVAPADCVFLDAQTET
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHHHHHEEECCCCEEEEECCCCC
ELLELEADEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAP
HHEEECHHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCEEEEECCCCCCCEEEEECCCCCC
QAAGVIHSDFERGFIKAEIVSFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFKFN
HHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCHHHCCCCEEEECCEEEEEEEC
V
C
>Mature Secondary Structure 
TLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLGRLSEIFGS
EEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCCHHHHHHHHHHCC
ERILPATVSFVDIAGIVKGASEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVN
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PATDISVINTELILADLQTVEKALPRLEKDARKDKALGEVLDETKKALEILSDDRTLFSA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
EKAGEIDLALLRDLHLMTAKPFLYVFNSDEEVLTDDAKKDELRALVAPADCVFLDAQTET
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHHHHHEEECCCCEEEEECCCCC
ELLELEADEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAP
HHEEECHHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCEEEEECCCCCCCEEEEECCCCCC
QAAGVIHSDFERGFIKAEIVSFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFKFN
HHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCHHHCCCCEEEECCEEEEEEEC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]