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The map label for this gene is xseA

Identifier: 145295166

GI number: 145295166

Start: 1218472

End: 1219725

Strand: Reverse

Name: xseA

Synonym: cgR_1108

Alternate gene names: 145295166

Gene position: 1219725-1218472 (Counterclockwise)

Preceding gene: 145295168

Following gene: 145295165

Centisome position: 36.8

GC content: 60.37

Gene sequence:

>1254_bases
GTGTCGTCTGAGAAAGCTTCATCAAAATCAACCCCTGAGGCACCGTGGCCAGTCCGGGAAGTAAATACTCAAGTCAAGCA
GTGGATTGAACGGCTTGGCCATTTGTGGGTGGAGGGCCAGCTCGCTCAGATTAATGTGAAGCCCAATTGGAAGCTGTCGT
ATTTGACGCTTCGTGATGTGGAGCAAGAAGTGTCTGTGCAGCTGACCTGCCCGACGGACATTATCCGCAATCGTCCCACA
CCGCTCAAGGATGGCGACCGCGTGATTGTGTACGGCAAGCCCGCGTTTTATGCAGGCCGCGGCACTTTTTCGCTGTGGGT
GACTGATATCCGTCCCGTGGGTATTGGTGAGTTGCTGGCGCGCATTGAGGAGCTGCGTAAAAGGCTTGCTGCGGAGGGTC
TTTTTGATCCAGCTCGGAAGAAGCGACTGCCATTTCTGCCCAACCGCGTTGGTTTGATCACGGGACGTGGTTCAGCGGCT
GAGCGCGATGTGCTGAGCGTGGCTAAGGATCGCTGGCCGGAAGTGCAGTTTGAGGTGATCAACACGGCAGTTCAGGGCGC
TTCAGCTGTTCCTGAAATCATCGAGGCGTTGCGGGCTTTAGATCAGGACCCTCGCGTGGATGTCATCATCATTGCCCGCG
GTGGCGGTTCTGTGGAGGATCTGCTCCCCTTCTCTGAGGAGGCCTTGCAGCGCGCAGTCGCGGCAGCGCAGACGCCCGTG
GTGTCCGCGATTGGCCACGAACCAGATACGCCGGTGTTGGACAATGTCGCCGACCTTCGCGCGGCGACCCCGACCGATGC
AGCAAAGCGCGTGGTGCCTGATGTGGCAGAAGAACGCATGTTGATCAATCAGCTTCGCAGTCGTAGTGCCGCGGCGTTGC
GCGGTTGGGTGCAGCGCGAGCAGCAGGCGTTGGCAGCGATTCGCACCAGGCCGGTGCTGGCTGATCCGATGACCCCGATT
AACCGCCGACGTGATGAGATTGCCCAGGCTGTGGGCTTGATTAGGCGCGATGTCACCCATCTCGTCCGCACCGAGCAAGC
ACTGGTGGCGTCGTTGCGCGCACAGGTTTCCGCGCTCGGCCCGTCCGCAACCTTGGCGCGCGGTTATTCCGTGGTGCAGG
TTATTCCTCGCGACGGCAGCGCCCCGGAAGTGGTCACCACCATCGAGCAATCACCGCCCGGCAGCCAGCTGCGCATCCGC
GTTGCCGACGGCTCCATCACTGCGGCATCCATGGGCACCCAGCAAGCAAACTAA

Upstream 100 bases:

>100_bases
TCCAACGTTGAGGCTAAACACCTAGACTGGGAATGCAACCACCCCGACAAAGGCGGGGTAATTCACTTTTAGCTGGTGGA
AGAAGGAGAATCACACGCCT

Downstream 100 bases:

>100_bases
AAACTTAGGAGAATGAAGAAATGACCAATCCAGATATCGTCGGTTCCGGCCAAGGCAACGATTCCTTCGAGCCAGTCGCC
CAATTATCCTACGAACGCGC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDVEQEVSVQLTCPTDIIRNRPT
PLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLARIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAA
ERDVLSVAKDRWPEVQFEVINTAVQGASAVPEIIEALRALDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQREQQALAAIRTRPVLADPMTPI
NRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALGPSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIR
VADGSITAASMGTQQAN

Sequences:

>Translated_417_residues
MSSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDVEQEVSVQLTCPTDIIRNRPT
PLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLARIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAA
ERDVLSVAKDRWPEVQFEVINTAVQGASAVPEIIEALRALDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQREQQALAAIRTRPVLADPMTPI
NRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALGPSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIR
VADGSITAASMGTQQAN
>Mature_416_residues
SSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDVEQEVSVQLTCPTDIIRNRPTP
LKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLARIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAAE
RDVLSVAKDRWPEVQFEVINTAVQGASAVPEIIEALRALDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPVV
SAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQREQQALAAIRTRPVLADPMTPIN
RRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALGPSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIRV
ADGSITAASMGTQQAN

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=31.2925170068027, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_CORGB (A4QCY8)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137987.1
- STRING:   A4QCY8
- GeneID:   4991920
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1108
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   PWPVRTV
- ProtClustDB:   PRK00286
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L

EC number: =3.1.11.6

Molecular weight: Translated: 45523; Mature: 45391

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCEEEEEEECCCCEEEEEEHHCC
EQEVSVQLTCPTDIIRNRPTPLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLA
CCCCEEEEECCHHHHCCCCCCCCCCCEEEEEECCEEEECCCEEEEEEECCCCCCHHHHHH
RIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAAERDVLSVAKDRWPEVQFEVI
HHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
NTAVQGASAVPEIIEALRALDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
HHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHCCH
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQRE
HHHHCCCCCCCHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQALAAIRTRPVLADPMTPINRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIRVADGSITAASMGTQQAN
CCHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCEEEHHCCCCCCC
>Mature Secondary Structure 
SSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCEEEEEEECCCCEEEEEEHHCC
EQEVSVQLTCPTDIIRNRPTPLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLA
CCCCEEEEECCHHHHCCCCCCCCCCCEEEEEECCEEEECCCEEEEEEECCCCCCHHHHHH
RIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAAERDVLSVAKDRWPEVQFEVI
HHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
NTAVQGASAVPEIIEALRALDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
HHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHCCH
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQRE
HHHHCCCCCCCHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQALAAIRTRPVLADPMTPINRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIRVADGSITAASMGTQQAN
CCHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA