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The map label for this gene is coaA

Identifier: 145295143

GI number: 145295143

Start: 1197930

End: 1198901

Strand: Reverse

Name: coaA

Synonym: cgR_1086

Alternate gene names: 145295143

Gene position: 1198901-1197930 (Counterclockwise)

Preceding gene: 145295147

Following gene: 145295137

Centisome position: 36.17

GC content: 55.97

Gene sequence:

>972_bases
ATGGCAGAGCAAAACGCTGCAAGCACAACTGGTGTGAAACCTTCCCCACGCACACCAGATTTCAGCCCCTACCTTGATTT
CGACCGCGCACAATGGCGCGAGCTGAGAAACTCAATGCCTCAGGTGCTGACCCAAAAAGAAGTCATTGAACTTCGAGGCA
TCGGAGAAAACATTGACCTCGCTGAAGTGGCAGAAGTCTACCTTCCGCTGTCCCGTCTGATTCACCTCCAGGTAGCGGCC
CGACAGCAACTTACCGCAGCCACCGAAACCTTCCTCGGAACTTCCCCCTCCACCTCTGTGCCGTTTGTCATTGGTGTCGC
GGGATCCGTCGCCGTCGGTAAATCAACCACCGCCCGACTCCTCCAAGTTCTACTTCAGCGCTGGAATTCCCACCCCCGCG
TGGACCTCGTCACCACCGACGGATTCCTCTACCCCGGCGCGGAACTAACCCGCCGCGGATTAATGTCCCGAAAAGGATTC
CCCGAAAGCTACGACCAACGTGCACTCCTCCGCTTTGTCACCGACGTAAAATCCGGAAAACTCGAAGTCAACGCACCTGT
CTACTCCCACACCGCGTACGACCGAGTTCCAGGCGAATTCACCACAGTCCGCCAACCCGACATTTTGATCGTTGAAGGCC
TAAACGTCCTCCAAACTGGCCCAACATTGATGGTCAGTGACCTTTTCGACTTCAGCGTCTACGTTGATGCCCGCACCGAA
GACATCGAAAAATGGTACATCGACCGCTTCCTCAAACTCCGCGACACTGCATTCCGTCGCCCCGGTGCCCACTTCTCCCA
TTACGCCGACATGGCTGATCCAGAGTCCATCGCCGTCGCTCGAGAACTGTGGCAATCGATCAACCTGCCCAACTTGGTGG
AGAACATTCTTCCCACCCGAGTTCGCGCGTCGTTGGTACTGAAAAAAGGTAGCGATCACTTGGTGGAACGGGTGAGGATG
CGCAAGATCTAG

Upstream 100 bases:

>100_bases
GCATGAGTTTACTCACGTGCCCACGTCTTTTAGCCACCCATTGAAGTGAAAAAATAACCCCGATCACACTAATGGAGTAG
CTAAGGTGCACAATGGATTC

Downstream 100 bases:

>100_bases
GGGTTCTTGCTGGTTTTGAGTAGGGAATCCCTTGCTAAGTGGCAGATTTCTTCGGTTCGGCCGTGTTTGACCCTGTTCGT
CCGCGCCAACCAAACCAGAT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAEQNAASTTGVKPSPRTPDFSPYLDFDRAQWRELRNSMPQVLTQKEVIELRGIGENIDLAEVAEVYLPLSRLIHLQVAA
RQQLTAATETFLGTSPSTSVPFVIGVAGSVAVGKSTTARLLQVLLQRWNSHPRVDLVTTDGFLYPGAELTRRGLMSRKGF
PESYDQRALLRFVTDVKSGKLEVNAPVYSHTAYDRVPGEFTTVRQPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARTE
DIEKWYIDRFLKLRDTAFRRPGAHFSHYADMADPESIAVARELWQSINLPNLVENILPTRVRASLVLKKGSDHLVERVRM
RKI

Sequences:

>Translated_323_residues
MAEQNAASTTGVKPSPRTPDFSPYLDFDRAQWRELRNSMPQVLTQKEVIELRGIGENIDLAEVAEVYLPLSRLIHLQVAA
RQQLTAATETFLGTSPSTSVPFVIGVAGSVAVGKSTTARLLQVLLQRWNSHPRVDLVTTDGFLYPGAELTRRGLMSRKGF
PESYDQRALLRFVTDVKSGKLEVNAPVYSHTAYDRVPGEFTTVRQPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARTE
DIEKWYIDRFLKLRDTAFRRPGAHFSHYADMADPESIAVARELWQSINLPNLVENILPTRVRASLVLKKGSDHLVERVRM
RKI
>Mature_322_residues
AEQNAASTTGVKPSPRTPDFSPYLDFDRAQWRELRNSMPQVLTQKEVIELRGIGENIDLAEVAEVYLPLSRLIHLQVAAR
QQLTAATETFLGTSPSTSVPFVIGVAGSVAVGKSTTARLLQVLLQRWNSHPRVDLVTTDGFLYPGAELTRRGLMSRKGFP
ESYDQRALLRFVTDVKSGKLEVNAPVYSHTAYDRVPGEFTTVRQPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARTED
IEKWYIDRFLKLRDTAFRRPGAHFSHYADMADPESIAVARELWQSINLPNLVENILPTRVRASLVLKKGSDHLVERVRMR
KI

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=309, Percent_Identity=53.7216828478964, Blast_Score=337, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_CORGB (A4QCW5)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137964.1
- ProteinModelPortal:   A4QCW5
- SMR:   A4QCW5
- STRING:   A4QCW5
- GeneID:   4993798
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1086
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 36322; Mature: 36191

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQNAASTTGVKPSPRTPDFSPYLDFDRAQWRELRNSMPQVLTQKEVIELRGIGENIDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AEVAEVYLPLSRLIHLQVAARQQLTAATETFLGTSPSTSVPFVIGVAGSVAVGKSTTARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEECCCHHHHHH
LQVLLQRWNSHPRVDLVTTDGFLYPGAELTRRGLMSRKGFPESYDQRALLRFVTDVKSGK
HHHHHHHHCCCCCEEEEEECCEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
LEVNAPVYSHTAYDRVPGEFTTVRQPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARTE
EEECCCEECCCHHHCCCCCEEECCCCCEEEECCCHHHHCCCCEEEHHHHCEEEEEECCHH
DIEKWYIDRFLKLRDTAFRRPGAHFSHYADMADPESIAVARELWQSINLPNLVENILPTR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VRASLVLKKGSDHLVERVRMRKI
HHHHHHEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
AEQNAASTTGVKPSPRTPDFSPYLDFDRAQWRELRNSMPQVLTQKEVIELRGIGENIDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AEVAEVYLPLSRLIHLQVAARQQLTAATETFLGTSPSTSVPFVIGVAGSVAVGKSTTARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEECCCHHHHHH
LQVLLQRWNSHPRVDLVTTDGFLYPGAELTRRGLMSRKGFPESYDQRALLRFVTDVKSGK
HHHHHHHHCCCCCEEEEEECCEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
LEVNAPVYSHTAYDRVPGEFTTVRQPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARTE
EEECCCEECCCHHHCCCCCEEECCCCCEEEECCCHHHHCCCCEEEHHHHCEEEEEECCHH
DIEKWYIDRFLKLRDTAFRRPGAHFSHYADMADPESIAVARELWQSINLPNLVENILPTR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VRASLVLKKGSDHLVERVRMRKI
HHHHHHEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA