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The map label for this gene is gap [H]

Identifier: 145295095

GI number: 145295095

Start: 1146438

End: 1147829

Strand: Direct

Name: gap [H]

Synonym: cgR_1038

Alternate gene names: 145295095

Gene position: 1146438-1147829 (Clockwise)

Preceding gene: 145295094

Following gene: 145295098

Centisome position: 34.59

GC content: 56.97

Gene sequence:

>1392_bases
ATGGTGCCGTTGATCGGGCGCCTGCACCGCAACAATAACGTGGTGGTTTCCGTATTCGGTCGTCTCCTTGTGAATGTCTC
AGACATCGATATCATCAAGTCTCATCGCTACGCCCGCCACATCATATCCAAGGAACTTCCACTGGAAAGCTCCTTGGATA
TTTTGCGCGAACTGGTAGATATGAACCTTGGTACCGCATCGATCGACCTGGGACAGCTGGCCTACAGCTTCGAAGAATCC
GAACGCACCGACCTGCGTGCCTTCCTGGAGGATGCTCTCGCGCCGGTCATTGGTGCGGAAACTGACATCAACCCAACTGA
TATCGTGCTGTACGGTTTCGGCCGCATCGGTCGCCTGCTGGCCCGCATCCTGGTTTCCCGCGAGGCACTGTATGACGGCG
CTCGTCTGCGCGCCATCGTGGTCCGCAAAAACGGTGAAGAAGACCTGGTCAAGCGCGCATCCTTGCTGCGTCGTGATTCT
GTCCACGGTGGATTCGATGGCACCATCACCACCGATTATGACAACAACATCATCTGGGCCAACGGCACCCCAATTAAGGT
CATTTACTCCAATGACCCAGCCACCATTGATTACACCGAATACGGCATCAATGACGCCGTCGTGGTGGACAACACCGGCC
GCTGGCGTGACCGCGAAGGCCTGTCCCAGCACCTCAAGTCCAAGGGTGTTGCCAAGGTTGTGCTCACCGCGCCGGGCAAG
GGTGATCTGAAGAATATCGTTTACGGCATCAACCACACCGACATCACCGCAGATGATCAGATCGTTTCCGCAGCATCATG
CACCACCAATGCCATTACCCCAGTGCTCAAGGTGATCAATGATCGCTACGGCGTGGAATTCGGCCACGTAGAAACCGTTC
ACTCCTTCACCAATGACCAGAACCTGATCGACAACTTCCACAAGGGTTCTCGCCGTGGTCGCGCAGCAGGTCTGAATATG
GTTCTCACCGAAACCGGCGCTGCAAAGGCTGTATCCAAGGCGCTTCCAGAGCTGGAAGGCAAGCTCACCGGCAATGCCAT
CCGCGTTCCTACCCCTGACGTGTCCATGGCTGTGCTCAACTTGACCCTGAAAACGGAGGTGGACCGCGATGAGGTCAACG
AGTTCCTCCGCCGTGTGTCCCTGCACTCTGACTTGCGCCAGCAAATCGACTGGATCCGTTCCCCAGAGGTTGTTTCCACT
GACTTCGTGGGCACCACCCACGCGGGCATTGTTGATGGTCTAGCCACCATCGCAACCGGTCGCCACCTGGTGCTTTACGT
GTGGTACGACAACGAGTTCGGCTACTCCAACCAGGTGATTCGCATCGTCGAGGAGATCGCCGGCGTGCGTCCTCGCGTGT
ACCCGGAGCGCAAGCAGCCAGCCGTACTATAG

Upstream 100 bases:

>100_bases
GTGATAAACCCCGGGTTAACCCCACGCCTAAGTCAGTGAAGGACTTTTTATGACGCACAACCACAAGGACTGGAACGATC
GCATCGCAGTTGCGGAGGAC

Downstream 100 bases:

>100_bases
GTTATCCAAGCCTAATACGCTACGATTAGGCATATGAGTAAGCGTAAGTCACGGGTGAAAGTTACCCACAATCCGCTGGG
CATGAAAGTCAAAGACACGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MVPLIGRLHRNNNVVVSVFGRLLVNVSDIDIIKSHRYARHIISKELPLESSLDILRELVDMNLGTASIDLGQLAYSFEES
ERTDLRAFLEDALAPVIGAETDINPTDIVLYGFGRIGRLLARILVSREALYDGARLRAIVVRKNGEEDLVKRASLLRRDS
VHGGFDGTITTDYDNNIIWANGTPIKVIYSNDPATIDYTEYGINDAVVVDNTGRWRDREGLSQHLKSKGVAKVVLTAPGK
GDLKNIVYGINHTDITADDQIVSAASCTTNAITPVLKVINDRYGVEFGHVETVHSFTNDQNLIDNFHKGSRRGRAAGLNM
VLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLNLTLKTEVDRDEVNEFLRRVSLHSDLRQQIDWIRSPEVVST
DFVGTTHAGIVDGLATIATGRHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVYPERKQPAVL

Sequences:

>Translated_463_residues
MVPLIGRLHRNNNVVVSVFGRLLVNVSDIDIIKSHRYARHIISKELPLESSLDILRELVDMNLGTASIDLGQLAYSFEES
ERTDLRAFLEDALAPVIGAETDINPTDIVLYGFGRIGRLLARILVSREALYDGARLRAIVVRKNGEEDLVKRASLLRRDS
VHGGFDGTITTDYDNNIIWANGTPIKVIYSNDPATIDYTEYGINDAVVVDNTGRWRDREGLSQHLKSKGVAKVVLTAPGK
GDLKNIVYGINHTDITADDQIVSAASCTTNAITPVLKVINDRYGVEFGHVETVHSFTNDQNLIDNFHKGSRRGRAAGLNM
VLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLNLTLKTEVDRDEVNEFLRRVSLHSDLRQQIDWIRSPEVVST
DFVGTTHAGIVDGLATIATGRHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVYPERKQPAVL
>Mature_463_residues
MVPLIGRLHRNNNVVVSVFGRLLVNVSDIDIIKSHRYARHIISKELPLESSLDILRELVDMNLGTASIDLGQLAYSFEES
ERTDLRAFLEDALAPVIGAETDINPTDIVLYGFGRIGRLLARILVSREALYDGARLRAIVVRKNGEEDLVKRASLLRRDS
VHGGFDGTITTDYDNNIIWANGTPIKVIYSNDPATIDYTEYGINDAVVVDNTGRWRDREGLSQHLKSKGVAKVVLTAPGK
GDLKNIVYGINHTDITADDQIVSAASCTTNAITPVLKVINDRYGVEFGHVETVHSFTNDQNLIDNFHKGSRRGRAAGLNM
VLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLNLTLKTEVDRDEVNEFLRRVSLHSDLRQQIDWIRSPEVVST
DFVGTTHAGIVDGLATIATGRHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVYPERKQPAVL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=37.5739644970414, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=37.6506024096386, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=39.0532544378698, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789295, Length=348, Percent_Identity=35.3448275862069, Blast_Score=195, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17534677, Length=351, Percent_Identity=38.4615384615385, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17534679, Length=351, Percent_Identity=38.1766381766382, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17568413, Length=342, Percent_Identity=39.4736842105263, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=39.4736842105263, Blast_Score=205, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6322409, Length=342, Percent_Identity=39.766081871345, Blast_Score=216, Evalue=8e-57,
Organism=Saccharomyces cerevisiae, GI6321631, Length=342, Percent_Identity=38.5964912280702, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322468, Length=342, Percent_Identity=38.3040935672515, Blast_Score=207, Evalue=4e-54,
Organism=Drosophila melanogaster, GI85725000, Length=341, Percent_Identity=38.1231671554252, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI22023983, Length=341, Percent_Identity=38.1231671554252, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI17933600, Length=341, Percent_Identity=38.41642228739, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI18110149, Length=341, Percent_Identity=38.41642228739, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI19922412, Length=340, Percent_Identity=36.1764705882353, Blast_Score=188, Evalue=8e-48,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 51211; Mature: 51211

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPLIGRLHRNNNVVVSVFGRLLVNVSDIDIIKSHRYARHIISKELPLESSLDILRELVD
CCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MNLGTASIDLGQLAYSFEESERTDLRAFLEDALAPVIGAETDINPTDIVLYGFGRIGRLL
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHH
ARILVSREALYDGARLRAIVVRKNGEEDLVKRASLLRRDSVHGGFDGTITTDYDNNIIWA
HHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEE
NGTPIKVIYSNDPATIDYTEYGINDAVVVDNTGRWRDREGLSQHLKSKGVAKVVLTAPGK
CCCEEEEEECCCCCEEEEHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
GDLKNIVYGINHTDITADDQIVSAASCTTNAITPVLKVINDRYGVEFGHVETVHSFTNDQ
CCHHHHEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEECCHHHHHHHCCCH
NLIDNFHKGSRRGRAAGLNMVLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLN
HHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEE
LTLKTEVDRDEVNEFLRRVSLHSDLRQQIDWIRSPEVVSTDFVGTTHAGIVDGLATIATG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCC
RHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVYPERKQPAVL
CEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVPLIGRLHRNNNVVVSVFGRLLVNVSDIDIIKSHRYARHIISKELPLESSLDILRELVD
CCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MNLGTASIDLGQLAYSFEESERTDLRAFLEDALAPVIGAETDINPTDIVLYGFGRIGRLL
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHH
ARILVSREALYDGARLRAIVVRKNGEEDLVKRASLLRRDSVHGGFDGTITTDYDNNIIWA
HHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEE
NGTPIKVIYSNDPATIDYTEYGINDAVVVDNTGRWRDREGLSQHLKSKGVAKVVLTAPGK
CCCEEEEEECCCCCEEEEHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
GDLKNIVYGINHTDITADDQIVSAASCTTNAITPVLKVINDRYGVEFGHVETVHSFTNDQ
CCHHHHEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEECCHHHHHHHCCCH
NLIDNFHKGSRRGRAAGLNMVLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLN
HHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEE
LTLKTEVDRDEVNEFLRRVSLHSDLRQQIDWIRSPEVVSTDFVGTTHAGIVDGLATIATG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCC
RHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVYPERKQPAVL
CEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680173 [H]