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The map label for this gene is ybdL [H]

Identifier: 145294983

GI number: 145294983

Start: 1026096

End: 1027307

Strand: Direct

Name: ybdL [H]

Synonym: cgR_0928

Alternate gene names: 145294983

Gene position: 1026096-1027307 (Clockwise)

Preceding gene: 145294982

Following gene: 145294988

Centisome position: 30.96

GC content: 52.64

Gene sequence:

>1212_bases
TTGAATCCTTTGCGCACCAATCAATGGGGGATCAAATATAGTAGCTGCATGAGTAATGACTTCGTCGTTTCTAGGCTTAG
ACCCTTTGGTGAAACGATTTTTGCAACCATGACCCAGCGAGCTGTTGAGGCGGGTGCAATCAATCTTGGTCAGGGCTTTC
CTGATGAGGATGGTCCTCGTCGGATGTTAGAGATCGCGTCGGAGCAGATTCTCGGGGGAAATAATCAGTATTCGGCGGGG
CGTGGGGATGCTTCGTTGAGGGCAGCTGTGGCTCGTGATCATTTGGAGAGGTTTGATCTGGAGTACAACCCTGATTCGGA
GGTGTTGATCACGGTGGGGGCCACTGAGGCGATTACGGCGACTGTGTTGGGTTTGGTGGAGCCTGGGGATGAAGTGATCG
TTTTGGAACCGTATTACGATGCGTATGCGGCGGCTATTGCGTTGGCGGGGGCGACGCGGGTGGCGGTTCCTTTGCAGGAG
GTGGAGAACTCGTGGGAAGTGGATGTCGATAAGTTGCATGCGGCGGTGACTAAGAAGACGCGGATGATTATCGTTAATTC
GCCGCATAATCCGACGGGTTCGGTGTTTTCTAAGAAGGCGTTGAAGCAGTTGGCGGGTATTGCTCGTGCGTATGACTTGT
TGGTGTTGTCAGATGAGGTGTATGAGCATCTTGTTTTTGATGATCAGAAGCATGTGAGTGTCGCGAAGCTGCCTGGTATG
TGGGATCGCACAGTGACGGTGTCGTCGGCGGCGAAGACGTTCAATGTGACTGGTTGGAAGACGGGGTGGGCGTTGGCACC
GGAGCCGTTGTTGGAGGCGGTGTTGAAGGCAAAGCAGTTTATGTCTTATGTGGGGGCTACACCTTTTCAGCCGGCTGTGG
CGCATGCGATTGAACATGAGCAGAAGTGGGTGTCAAAGATGTCTAAGGGGCTTGAGCTCAAGCGGGATATTTTGCGTACT
GCGTTAGATAAGGCGGGGCTGAAGACTCATGACAGTAAGGGCACGTATTTCATCGTTGCGGATATTGGGGATCGTGATGG
TGCGGAGTTCTGTTTTGAGTTGATTGAGAAGGTTGGGGTGGCGGCGATTCCGGTGCAGGCGTTTGTGGATCATCCGAAGA
AGTGGTCGTCGAAGGTTCGTTTTGCGTTTTGTAAAAAAGAAGAGACGCTCCGCGAAGCTGCGGAGCGTCTCAAGGGGATT
AAGAAACTATAG

Upstream 100 bases:

>100_bases
TGTTTGTTTCGTGCTTCTTCTCTTTTGTGCTTTCTAGGCCCCTGTGCACGCGGCACCTGTGCCTGGGGTGGGCGTCGACA
AGCACAAACTTTTTGCTTAA

Downstream 100 bases:

>100_bases
TTTGAACAGGTTGTTGGGGGTCTTTTTAACGTCCTCCAACTTGCCGCGGTTCTTTTCTAGTTTGGCCCAGAGTTCGTGGG
GGATAGTTTTCTCGGCTTCA

Product: aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNPLRTNQWGIKYSSCMSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQYSAG
RGDASLRAAVARDHLERFDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQE
VENSWEVDVDKLHAAVTKKTRMIIVNSPHNPTGSVFSKKALKQLAGIARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGM
WDRTVTVSSAAKTFNVTGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRDILRT
ALDKAGLKTHDSKGTYFIVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGI
KKL

Sequences:

>Translated_403_residues
MNPLRTNQWGIKYSSCMSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQYSAG
RGDASLRAAVARDHLERFDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQE
VENSWEVDVDKLHAAVTKKTRMIIVNSPHNPTGSVFSKKALKQLAGIARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGM
WDRTVTVSSAAKTFNVTGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRDILRT
ALDKAGLKTHDSKGTYFIVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGI
KKL
>Mature_403_residues
MNPLRTNQWGIKYSSCMSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQYSAG
RGDASLRAAVARDHLERFDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQE
VENSWEVDVDKLHAAVTKKTRMIIVNSPHNPTGSVFSKKALKQLAGIARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGM
WDRTVTVSSAAKTFNVTGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRDILRT
ALDKAGLKTHDSKGTYFIVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGI
KKL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=421, Percent_Identity=34.916864608076, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI56713256, Length=405, Percent_Identity=35.0617283950617, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI95147551, Length=420, Percent_Identity=33.3333333333333, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI169881279, Length=420, Percent_Identity=33.3333333333333, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=34.1059602649007, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI4507369, Length=197, Percent_Identity=32.994923857868, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI149944424, Length=205, Percent_Identity=29.2682926829268, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4885351, Length=188, Percent_Identity=33.5106382978723, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI19263340, Length=187, Percent_Identity=32.620320855615, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI215599424, Length=187, Percent_Identity=32.620320855615, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI187936925, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI14211921, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI7705897, Length=341, Percent_Identity=21.7008797653959, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI33469970, Length=341, Percent_Identity=21.7008797653959, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786816, Length=389, Percent_Identity=38.3033419023136, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=28.0927835051546, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788627, Length=194, Percent_Identity=31.9587628865979, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787909, Length=132, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787710, Length=320, Percent_Identity=27.8125, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=430, Percent_Identity=34.6511627906977, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71994476, Length=405, Percent_Identity=35.3086419753086, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17567369, Length=403, Percent_Identity=33.0024813895782, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17567663, Length=411, Percent_Identity=23.3576642335766, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=34.3669250645995, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320317, Length=359, Percent_Identity=23.6768802228412, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=209, Percent_Identity=28.7081339712919, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573069, Length=436, Percent_Identity=35.0917431192661, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24646114, Length=436, Percent_Identity=35.0917431192661, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI28573067, Length=436, Percent_Identity=35.0917431192661, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI28573065, Length=436, Percent_Identity=35.0917431192661, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI18859735, Length=201, Percent_Identity=29.3532338308458, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24641770, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641760, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641768, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641766, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641764, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551451, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 44349; Mature: 44349

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLRTNQWGIKYSSCMSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPR
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHH
RMLEIASEQILGGNNQYSAGRGDASLRAAVARDHLERFDLEYNPDSEVLITVGATEAITA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHH
TVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQEVENSWEVDVDKLHAAVTKKT
HHHHHCCCCCCEEEECCCHHHHHHHHHHHCCHHEEEEHHHHCCCCCCCHHHHHHHHHCCE
RMIIVNSPHNPTGSVFSKKALKQLAGIARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGM
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCCEEHHHCCCC
WDRTVTVSSAAKTFNVTGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHE
CCCEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QKWVSKMSKGLELKRDILRTALDKAGLKTHDSKGTYFIVADIGDRDGAEFCFELIEKVGV
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
AAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGIKKL
EEECHHHHHCCCHHHHCCHHEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPLRTNQWGIKYSSCMSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPR
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHH
RMLEIASEQILGGNNQYSAGRGDASLRAAVARDHLERFDLEYNPDSEVLITVGATEAITA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHH
TVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQEVENSWEVDVDKLHAAVTKKT
HHHHHCCCCCCEEEECCCHHHHHHHHHHHCCHHEEEEHHHHCCCCCCCHHHHHHHHHCCE
RMIIVNSPHNPTGSVFSKKALKQLAGIARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGM
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCCEEHHHCCCC
WDRTVTVSSAAKTFNVTGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHE
CCCEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QKWVSKMSKGLELKRDILRTALDKAGLKTHDSKGTYFIVADIGDRDGAEFCFELIEKVGV
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
AAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGIKKL
EEECHHHHHCCCHHHHCCHHEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]