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The map label for this gene is nudC [H]

Identifier: 145294941

GI number: 145294941

Start: 978774

End: 979490

Strand: Direct

Name: nudC [H]

Synonym: cgR_0887

Alternate gene names: 145294941

Gene position: 978774-979490 (Clockwise)

Preceding gene: 145294940

Following gene: 145294942

Centisome position: 29.53

GC content: 53.56

Gene sequence:

>717_bases
ATGAGAATTCTTCCCATCGGCCCCCACGATGAAATCGCCGTCAACGGATCAATCGTCTTTCTATCCGAGCACGACGGAGA
CATCGTATCGGTCGGCCCCGACCTCGGCACGGTGCGAGTTATCCTTGAAGAGATCGAAAGTTTAGGTACACCGACGGCAC
CCCGCGATCTGGGTTCTCGGGAAGTCGACGCATGCGTATCGTTGCTCCGCAACCGGGAGTTAGTGCGATTCGATCCCCAC
GATGGCAGTGAATTAACCTATCGGGAACATAGCGTTGCTTACGGTGCGAGTGGCAAGCCATTGTTTCCCCGATTGGATCC
AGCGGTGATCGGCATTGTGGAGCTGCGGGGTGAGGATCGTTTGCTTCTGGGCATGAATGCGCAGAAACGCCAACGTTATT
CATTAATCGCAGGTTATGTTTCGCATGGTGAGTCGCTGGAAGACGCATTCGCTAGGGAAGTGTTCGAGGAAGCAGCGCGC
CGGGTATCTGAGATTTCTTATGTGTCGTCTCAACCATGGCCGATCTCTGGTTCGCTGATGTTGGGTATGAAGGGCTTCAC
GGAAGATGAGTTGCCTCAAGGCGAAACTGATGGTGAATTAGCGGAGACAATCTGGGCTTCGCCACTAGACATTATCGATC
GTAAGATTCCGATCGCCCCACCCGGATCGATTGCCTACGACATGATCAACGCCTGGGCGCGAGATAAACAAAACTAA

Upstream 100 bases:

>100_bases
GTGAGCTCTACCGCATCGACTCCCCAGAAGCAGAAACTGTAGAGCCCGGCGATCGTCTCCTTTACGTTCGCCGAGTATTT
AGCGAGGAGGTAAATGACAA

Downstream 100 bases:

>100_bases
GGGAGCTTTTTACAGTGATCAATTTGCAGGACCTCGACGAGGATCAACGCATCGCTGCTTCTGCGCCTCGCGGACCAGTG
TGCATTCTCGCCGGAGCCGG

Product: NTP pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRILPIGPHDEIAVNGSIVFLSEHDGDIVSVGPDLGTVRVILEEIESLGTPTAPRDLGSREVDACVSLLRNRELVRFDPH
DGSELTYREHSVAYGASGKPLFPRLDPAVIGIVELRGEDRLLLGMNAQKRQRYSLIAGYVSHGESLEDAFAREVFEEAAR
RVSEISYVSSQPWPISGSLMLGMKGFTEDELPQGETDGELAETIWASPLDIIDRKIPIAPPGSIAYDMINAWARDKQN

Sequences:

>Translated_238_residues
MRILPIGPHDEIAVNGSIVFLSEHDGDIVSVGPDLGTVRVILEEIESLGTPTAPRDLGSREVDACVSLLRNRELVRFDPH
DGSELTYREHSVAYGASGKPLFPRLDPAVIGIVELRGEDRLLLGMNAQKRQRYSLIAGYVSHGESLEDAFAREVFEEAAR
RVSEISYVSSQPWPISGSLMLGMKGFTEDELPQGETDGELAETIWASPLDIIDRKIPIAPPGSIAYDMINAWARDKQN
>Mature_238_residues
MRILPIGPHDEIAVNGSIVFLSEHDGDIVSVGPDLGTVRVILEEIESLGTPTAPRDLGSREVDACVSLLRNRELVRFDPH
DGSELTYREHSVAYGASGKPLFPRLDPAVIGIVELRGEDRLLLGMNAQKRQRYSLIAGYVSHGESLEDAFAREVFEEAAR
RVSEISYVSSQPWPISGSLMLGMKGFTEDELPQGETDGELAETIWASPLDIIDRKIPIAPPGSIAYDMINAWARDKQN

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=150, Percent_Identity=32, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI48994995, Length=133, Percent_Identity=35.3383458646617, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321371, Length=161, Percent_Identity=31.6770186335404, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 26164; Mature: 26164

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILPIGPHDEIAVNGSIVFLSEHDGDIVSVGPDLGTVRVILEEIESLGTPTAPRDLGSR
CEECCCCCCCCEEECCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHHCCCH
EVDACVSLLRNRELVRFDPHDGSELTYREHSVAYGASGKPLFPRLDPAVIGIVELRGEDR
HHHHHHHHHHCCCEEEECCCCCCCEEEECCCEEECCCCCCCCCCCCHHEEEEEEECCCCE
LLLGMNAQKRQRYSLIAGYVSHGESLEDAFAREVFEEAARRVSEISYVSSQPWPISGSLM
EEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
LGMKGFTEDELPQGETDGELAETIWASPLDIIDRKIPIAPPGSIAYDMINAWARDKQN
ECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRILPIGPHDEIAVNGSIVFLSEHDGDIVSVGPDLGTVRVILEEIESLGTPTAPRDLGSR
CEECCCCCCCCEEECCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHHCCCH
EVDACVSLLRNRELVRFDPHDGSELTYREHSVAYGASGKPLFPRLDPAVIGIVELRGEDR
HHHHHHHHHHCCCEEEECCCCCCCEEEECCCEEECCCCCCCCCCCCHHEEEEEEECCCCE
LLLGMNAQKRQRYSLIAGYVSHGESLEDAFAREVFEEAARRVSEISYVSSQPWPISGSLM
EEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
LGMKGFTEDELPQGETDGELAETIWASPLDIIDRKIPIAPPGSIAYDMINAWARDKQN
ECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]