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The map label for this gene is secA

Identifier: 145294922

GI number: 145294922

Start: 956501

End: 959038

Strand: Direct

Name: secA

Synonym: cgR_0868

Alternate gene names: 145294922

Gene position: 956501-959038 (Clockwise)

Preceding gene: 145294921

Following gene: 145294924

Centisome position: 28.86

GC content: 57.01

Gene sequence:

>2538_bases
GTGTTTGGATTGTCCAAGGTGCTCCGCGTCGGCGAAGGCCGTGCCGTGAAGCGACTTCACAAGATCGCTGACCAGGTTAT
CGCGCTTGAAGAAAAATTCGCCAACCTGACCGATGAGGAGCTCAAGGCAAAAACAGCCGAGTTCAAAGAACGCATCGCTG
GCGGTGAAGGCCTCGACGAAATCTTCCTCGAAGCATTCGCAACGGCCCGCGAAGCATCTTGGCGTGTGCTCGGCCAAAAG
CACTACCGAGTACAAATCATGGGTGGCGCAGCACTGCACTTCGGCAACGTTGCCGAAATGCGCACCGGTGAAGGCAAAAC
CCTCACCTGCGTGCTGCCCGCATATTTGAACGCACTTGAAGGTAAAGGCGTCCACGTTGTCACCGTCAACGATTACCTAG
CGAAACGTGACGCCGAAATGGTCGGTCGTGTCCACCGCTACCTGGGCCTCGAAGTGGGAGTCATCCTCTCCGACATGCGC
CCAGACGAGCGTCGCAAGGCCTACACCGCCGACATCACCTACGGCACCAACAACGAACTCGGCTTCGACTACCTGCGCGA
CAACATGGCACGCTCCTTAAGCGACCTCGTGCAGCGCGGCCACAACTACGCCATCGTCGACGAAGTGGACTCCATCCTCA
TCGACGAAGCCCGCACCCCACTGATCATCTCCGGACCAGTAGACGGCACATCGCAGTTCTACAATGTCTTCGCACAGATC
GTCCCACGCATGACCAAGGACGTTCACTACGAAGTCGACGAACGTAAAAAGACCGTCGGTGTGAAAGAAGAAGGCGTCGA
ATACGTCGAAGACCAACTCGGCATCGACAACCTCTACGCACCTGAGCACTCACAGCTGGTCAGCTACCTGAACAACGCCA
TCAAGGCACAGGAACTGTTCACCCGCGACAAGGACTACATCGTCCGCAACGGCGAAGTTATGATCGTCGACGGCTTCACC
GGCCGAGTCCTTGCCGGCCGCCGATACAACGAAGGCATGCACCAGGCGATCGAAGCCAAAGAGCGCGTAGAGATCAAAAA
CGAGAACCAGACCCTGGCGACCGTTACCCTCCAGAACTACTTCCGCCTCTACACCAAACTCGCCGGCATGACCGGTACTG
CAGAGACCGAAGCAGCAGAGCTCAACCAGATCTACAAGCTCGACGTCATCGCGATCCCAACCAACCGACCAAACCAGCGC
GAAGACTTGACCGACTTGGTGTACAAAACCCAAGAGGCTAAGTTCGCAGCAGTCGTCGACGACATCGCAGAACGCACCGA
AAAGGGCCAACCAGTCCTCGTCGGTACCGTCTCCGTCGAGCGCTCCGAATACCTCTCCCAGCTGTTGACCAAACGAGGCA
TCAAGCACAACGTCCTCAATGCGAAGCACCACGAGCAGGAAGCACAGATCGTTGCTCAGGCAGGTCTTCCAGGCGCCGTC
ACCGTTGCCACCAACATGGCGGGCCGTGGAACCGACATCGTGCTCGGCGGAAACCCAGAAATCCTCCTCGACATCAAACT
CCGCGAACGTGGACTTGATCCTTTCGAAGACGAAGAAAGCTACCAGGAAGCCTGGGACGCTGAACTTCCAGCAATGAAGC
AGCGATGCGAAGAACGCGGCGACAAAGTCCGCGAAGCCGGAGGACTCTACGTCCTTGGCACCGAACGCCACGAATCCCGA
CGCATCGATAACCAGCTGCGCGGTCGTTCTGCACGTCAGGGCGACCCAGGATCCACCCGCTTCTATCTCTCTATGCGCGA
CGACCTGATGGTTCGCTTCGTCGGCCCAACCATGGAAAACATGATGAACAGGCTCAACGTCCCAGACGATGTGCCCATCG
AATCCAAAACCGTCACCAACTCCATCAAGGGCGCCCAAGCTCAGGTGGAGAACCAGAACTTCGAAATGCGTAAGAACGTT
CTGAAGTACGACGAAGTCATGAACGAACAGCGCAAGGTTATCTATAGCGAGCGACGCGAAATCCTCGAATCCGCAGACAT
CTCCCGCTACATCCAAAACATGATCGAAGAAACAGTCAGCGCATACGTCGACGGCGCCACCGCCAACGGCTACGTCGAAG
ACTGGGACCTCGACAAACTCTGGAACGCCCTCGAAGCCCTCTACGACCCATCGATCAACTGGACCGACCTCGTCGAAGGC
AGCGAATACGGCAAACCAGGGGAGCTGTCCGCCGAAGATCTACGCACCGCACTCGTCAACGACGCCCACGCCGAATACGC
AAAACTCGAAGAAGCCGTATCCGCAATCGGCGGCGAAGCACAGATCCGCAACATCGAACGAATGGTGCTCATGCCAGTCA
TCGACACCAAATGGCGCGAACACCTCTACGAAATGGACTACCTGAAAGAAGGCATCGGCCTGCGCGCAATGGCACAGCGC
GACCCACTGGTCGAATACCAAAAAGAAGGCGGCGACATGTTCAACGGCATGAAAGACGGCATCAAGGAAGAAACCGTCCG
CCAGCTCTTCCTCCTCCGCAAGCAGTTCATCAAGCAAGACGCGGAAGTCGCTGACTAA

Upstream 100 bases:

>100_bases
GGTACTGTGTTTTAGGAACCGTGCGTAGTTTTAGGAACAGTGCGTACAATATAGGTTCGTTATCATTTTTCCGTATCGCT
ATTTATAAGGACGACTGCTC

Downstream 100 bases:

>100_bases
CTCAGAACCCTGAAATTCAGCATCCGCCACATGCCGCCCGATTCGGCCAATCGGGCGGCATATGCCGTTCTCCGAACACC
CATAGAAATACTCCCGCACA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 845; Mature: 845

Protein sequence:

>845_residues
MFGLSKVLRVGEGRAVKRLHKIADQVIALEEKFANLTDEELKAKTAEFKERIAGGEGLDEIFLEAFATAREASWRVLGQK
HYRVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEMVGRVHRYLGLEVGVILSDMR
PDERRKAYTADITYGTNNELGFDYLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQI
VPRMTKDVHYEVDERKKTVGVKEEGVEYVEDQLGIDNLYAPEHSQLVSYLNNAIKAQELFTRDKDYIVRNGEVMIVDGFT
GRVLAGRRYNEGMHQAIEAKERVEIKNENQTLATVTLQNYFRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQR
EDLTDLVYKTQEAKFAAVVDDIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHEQEAQIVAQAGLPGAV
TVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAWDAELPAMKQRCEERGDKVREAGGLYVLGTERHESR
RIDNQLRGRSARQGDPGSTRFYLSMRDDLMVRFVGPTMENMMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNV
LKYDEVMNEQRKVIYSERREILESADISRYIQNMIEETVSAYVDGATANGYVEDWDLDKLWNALEALYDPSINWTDLVEG
SEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRNIERMVLMPVIDTKWREHLYEMDYLKEGIGLRAMAQR
DPLVEYQKEGGDMFNGMKDGIKEETVRQLFLLRKQFIKQDAEVAD

Sequences:

>Translated_845_residues
MFGLSKVLRVGEGRAVKRLHKIADQVIALEEKFANLTDEELKAKTAEFKERIAGGEGLDEIFLEAFATAREASWRVLGQK
HYRVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEMVGRVHRYLGLEVGVILSDMR
PDERRKAYTADITYGTNNELGFDYLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQI
VPRMTKDVHYEVDERKKTVGVKEEGVEYVEDQLGIDNLYAPEHSQLVSYLNNAIKAQELFTRDKDYIVRNGEVMIVDGFT
GRVLAGRRYNEGMHQAIEAKERVEIKNENQTLATVTLQNYFRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQR
EDLTDLVYKTQEAKFAAVVDDIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHEQEAQIVAQAGLPGAV
TVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAWDAELPAMKQRCEERGDKVREAGGLYVLGTERHESR
RIDNQLRGRSARQGDPGSTRFYLSMRDDLMVRFVGPTMENMMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNV
LKYDEVMNEQRKVIYSERREILESADISRYIQNMIEETVSAYVDGATANGYVEDWDLDKLWNALEALYDPSINWTDLVEG
SEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRNIERMVLMPVIDTKWREHLYEMDYLKEGIGLRAMAQR
DPLVEYQKEGGDMFNGMKDGIKEETVRQLFLLRKQFIKQDAEVAD
>Mature_845_residues
MFGLSKVLRVGEGRAVKRLHKIADQVIALEEKFANLTDEELKAKTAEFKERIAGGEGLDEIFLEAFATAREASWRVLGQK
HYRVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEMVGRVHRYLGLEVGVILSDMR
PDERRKAYTADITYGTNNELGFDYLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQI
VPRMTKDVHYEVDERKKTVGVKEEGVEYVEDQLGIDNLYAPEHSQLVSYLNNAIKAQELFTRDKDYIVRNGEVMIVDGFT
GRVLAGRRYNEGMHQAIEAKERVEIKNENQTLATVTLQNYFRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQR
EDLTDLVYKTQEAKFAAVVDDIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHEQEAQIVAQAGLPGAV
TVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAWDAELPAMKQRCEERGDKVREAGGLYVLGTERHESR
RIDNQLRGRSARQGDPGSTRFYLSMRDDLMVRFVGPTMENMMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNV
LKYDEVMNEQRKVIYSERREILESADISRYIQNMIEETVSAYVDGATANGYVEDWDLDKLWNALEALYDPSINWTDLVEG
SEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRNIERMVLMPVIDTKWREHLYEMDYLKEGIGLRAMAQR
DPLVEYQKEGGDMFNGMKDGIKEETVRQLFLLRKQFIKQDAEVAD

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=859, Percent_Identity=49.592549476135, Blast_Score=794, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA1_CORGB (A4QC94)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137743.1
- ProteinModelPortal:   A4QC94
- SMR:   A4QC94
- STRING:   A4QC94
- GeneID:   4991812
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0868
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   SANIREQ
- ProtClustDB:   PRK12904
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 95452; Mature: 95452

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLSKVLRVGEGRAVKRLHKIADQVIALEEKFANLTDEELKAKTAEFKERIAGGEGLDE
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHH
IFLEAFATAREASWRVLGQKHYRVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALE
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCHHHEECCCCCEEEEEHHHHHHHHC
GKGVHVVTVNDYLAKRDAEMVGRVHRYLGLEVGVILSDMRPDERRKAYTADITYGTNNEL
CCCEEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHCEEEEEEEECCCCCC
GFDYLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQI
CHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
VPRMTKDVHYEVDERKKTVGVKEEGVEYVEDQLGIDNLYAPEHSQLVSYLNNAIKAQELF
HHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TRDKDYIVRNGEVMIVDGFTGRVLAGRRYNEGMHQAIEAKERVEIKNENQTLATVTLQNY
HCCCCEEEECCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHCEECCCCCEEEEEHHHHH
FRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQREDLTDLVYKTQEAKFAAVVD
HHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHH
DIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHEQEAQIVAQAGLPGAV
HHHHHHCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
TVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAWDAELPAMKQRCEERG
EEEECCCCCCCEEEECCCCCEEEEEEEHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
DKVREAGGLYVLGTERHESRRIDNQLRGRSARQGDPGSTRFYLSMRDDLMVRFVGPTMEN
HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEECCHHHHH
MMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNVLKYDEVMNEQRKVIYSERRE
HHHHCCCCCCCCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILESADISRYIQNMIEETVSAYVDGATANGYVEDWDLDKLWNALEALYDPSINWTDLVEG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCC
SEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRNIERMVLMPVIDTKWRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHHHH
HLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNGMKDGIKEETVRQLFLLRKQFIKQD
HHHHHHHHHHCCCCEEHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEVAD
CCCCC
>Mature Secondary Structure
MFGLSKVLRVGEGRAVKRLHKIADQVIALEEKFANLTDEELKAKTAEFKERIAGGEGLDE
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHH
IFLEAFATAREASWRVLGQKHYRVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALE
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCHHHEECCCCCEEEEEHHHHHHHHC
GKGVHVVTVNDYLAKRDAEMVGRVHRYLGLEVGVILSDMRPDERRKAYTADITYGTNNEL
CCCEEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHCEEEEEEEECCCCCC
GFDYLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQI
CHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
VPRMTKDVHYEVDERKKTVGVKEEGVEYVEDQLGIDNLYAPEHSQLVSYLNNAIKAQELF
HHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TRDKDYIVRNGEVMIVDGFTGRVLAGRRYNEGMHQAIEAKERVEIKNENQTLATVTLQNY
HCCCCEEEECCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHCEECCCCCEEEEEHHHHH
FRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQREDLTDLVYKTQEAKFAAVVD
HHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHH
DIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHEQEAQIVAQAGLPGAV
HHHHHHCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
TVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAWDAELPAMKQRCEERG
EEEECCCCCCCEEEECCCCCEEEEEEEHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
DKVREAGGLYVLGTERHESRRIDNQLRGRSARQGDPGSTRFYLSMRDDLMVRFVGPTMEN
HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEECCHHHHH
MMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNVLKYDEVMNEQRKVIYSERRE
HHHHCCCCCCCCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILESADISRYIQNMIEETVSAYVDGATANGYVEDWDLDKLWNALEALYDPSINWTDLVEG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCC
SEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRNIERMVLMPVIDTKWRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHHHH
HLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNGMKDGIKEETVRQLFLLRKQFIKQD
HHHHHHHHHHCCCCEEHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEVAD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA