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The map label for this gene is 145294745

Identifier: 145294745

GI number: 145294745

Start: 752295

End: 753626

Strand: Reverse

Name: 145294745

Synonym: cgR_0693

Alternate gene names: NA

Gene position: 753626-752295 (Counterclockwise)

Preceding gene: 145294746

Following gene: 145294739

Centisome position: 22.74

GC content: 54.73

Gene sequence:

>1332_bases
TTGTGTGGCTTGAAAGGTTGGAATCACTGTGTCTTGCAGCTAGTCTGCCACTCGCACTGCATTTACTGGATGTATTTGGA
ATGCTGCGCGGTCTTGATATTGGATTCGGTGGATAAAATGCGCAGACTCATCGCGGTTAGCTTGGCCGCTCTGTTTATTG
TGGCTTCCACTCCAGCGACGAGGGCACAGGAAGTAGAAGCTCTCGCTTGCCCCGAGGTAGCGATCGCCGATCCTTCCTCC
GCAGTTTTAGATGAACATCTTGCACAGTCATTATCCCAAGCTCACCAACTAGCAACTGGCGCCGGTGTGATGGTGGCAGT
TATCGACACCGGAGTATCCCTGCATCCACGTCTGCCCCACTTAATTCCCGGCGGTGATTTCGTGGGCGCCCACCAAAGCC
CCGATGTGCCAGGTGAACTTATCGATTGCGACGGACACGGCACCATCGTCGCCGGAATCATCGCCTCCCAAGGAAACCCC
GGCACCGGCTGGCCATATGACGGCAGCTCCGATCCCTATATCGGTGTCGCCCCAGATTCCGGAATCATCTCCATTAAACA
AACCAGCTCATATGTGCGTACTCGTGAAGATTCCAACGTCGGAACGCTGAGCACCCTGGCGGAATCCATCCACCGAGCTC
TCGATTCCGATGCCCACGTGATCAATATTTCCGTGGTGTCCTGTTTGCCCCAATCACCCGACGAGGCCGCATCGTTCCAG
CCTCTGACGGATGCTCTTAACAGAGCAGAACTTCAAGGGGTGATAGTGGTGGCAGCAGCAGGAAACCTCGGGCAGGATTG
TCCAGTTGGATCTACCGTTTATCCTGCACATTCAGACACTGTGCTCTCTGTGTCGGCGCGTTTTGATTCTCACACGCTTG
CAGAATATTCCATGCCTGGCAACCAACAAATCCTTTCTGCACCAAGCCACATTCAGGCTGGTCTATCACCGCGTGGCGAC
GGCTTCGCCAGCCACATGATCACCACCGCTGGTGAAAGCCCCTTCGAGGGCACCAGTTTTGCTGCTCCAGTTGTCAGCGC
CACAGCTGCACTGCTTCGCCAGCATTTTCCCTTTGCCACACCCTATGAAATTCGTGCACGAATCTTCAACAGCATCGACC
CCGCAAGAGGCGCTATTGATCCCTACCTAGCACTTACTCAAGAAATCTATCCCACCACTCCCCTGGTTCATGAGATCGCA
CTAAGTGTTCCCACGCCGCCGGATGATTCTCCACGGGAGCGGGGCATCCTAGTTACCGCAATCATTGTTGGGTTGCTCGC
GATGTTAGCTGTGCTGATGGGACTACGCCGAATTCATCAGCGCACAGCCTAA

Upstream 100 bases:

>100_bases
GGTTCACTAGTTGCACTGATCGGTTCTGTGGTTATCATCGCTGCGCTGGTCAGCGTGGCATTGTGGATCAGTACAGTCCC
CACGCTGGAACCCACCACCA

Downstream 100 bases:

>100_bases
TATTGCTGCTTAGACCAAATGGCTTCTCCGGTACCGAAATGTAAACTAAGAGGTTGAGAATCCTCACATGGGTCTTGGTG
TAGGTGAGGTCTGTTTAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MCGLKGWNHCVLQLVCHSHCIYWMYLECCAVLILDSVDKMRRLIAVSLAALFIVASTPATRAQEVEALACPEVAIADPSS
AVLDEHLAQSLSQAHQLATGAGVMVAVIDTGVSLHPRLPHLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNP
GTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSNVGTLSTLAESIHRALDSDAHVINISVVSCLPQSPDEAASFQ
PLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSDTVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGD
GFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFATPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIA
LSVPTPPDDSPRERGILVTAIIVGLLAMLAVLMGLRRIHQRTA

Sequences:

>Translated_443_residues
MCGLKGWNHCVLQLVCHSHCIYWMYLECCAVLILDSVDKMRRLIAVSLAALFIVASTPATRAQEVEALACPEVAIADPSS
AVLDEHLAQSLSQAHQLATGAGVMVAVIDTGVSLHPRLPHLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNP
GTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSNVGTLSTLAESIHRALDSDAHVINISVVSCLPQSPDEAASFQ
PLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSDTVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGD
GFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFATPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIA
LSVPTPPDDSPRERGILVTAIIVGLLAMLAVLMGLRRIHQRTA
>Mature_443_residues
MCGLKGWNHCVLQLVCHSHCIYWMYLECCAVLILDSVDKMRRLIAVSLAALFIVASTPATRAQEVEALACPEVAIADPSS
AVLDEHLAQSLSQAHQLATGAGVMVAVIDTGVSLHPRLPHLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNP
GTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSNVGTLSTLAESIHRALDSDAHVINISVVSCLPQSPDEAASFQ
PLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSDTVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGD
GFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFATPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIA
LSVPTPPDDSPRERGILVTAIIVGLLAMLAVLMGLRRIHQRTA

Specific function: Shows keratinolytic activity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 46672; Mature: 46672

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGLKGWNHCVLQLVCHSHCIYWMYLECCAVLILDSVDKMRRLIAVSLAALFIVASTPAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RAQEVEALACPEVAIADPSSAVLDEHLAQSLSQAHQLATGAGVMVAVIDTGVSLHPRLPH
HHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
LIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNPGTGWPYDGSSDPYIGVAPDS
CCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCC
GIISIKQTSSYVRTREDSNVGTLSTLAESIHRALDSDAHVINISVVSCLPQSPDEAASFQ
CEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHCCCC
PLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSDTVLSVSARFDSHTLAEYSMPG
HHHHHHHHHHHCEEEEEEECCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCHHHCCCCC
NQQILSAPSHIQAGLSPRGDGFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFAT
CHHHHCCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIALSVPTPPDDSPRERGILVTA
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHCCCHHHH
IIVGLLAMLAVLMGLRRIHQRTA
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCGLKGWNHCVLQLVCHSHCIYWMYLECCAVLILDSVDKMRRLIAVSLAALFIVASTPAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RAQEVEALACPEVAIADPSSAVLDEHLAQSLSQAHQLATGAGVMVAVIDTGVSLHPRLPH
HHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
LIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNPGTGWPYDGSSDPYIGVAPDS
CCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCC
GIISIKQTSSYVRTREDSNVGTLSTLAESIHRALDSDAHVINISVVSCLPQSPDEAASFQ
CEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHCCCC
PLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSDTVLSVSARFDSHTLAEYSMPG
HHHHHHHHHHHCEEEEEEECCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCHHHCCCCC
NQQILSAPSHIQAGLSPRGDGFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFAT
CHHHHCCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIALSVPTPPDDSPRERGILVTA
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHCCCHHHH
IIVGLLAMLAVLMGLRRIHQRTA
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1369007; 11058132; 1370008 [H]