Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 145294728

GI number: 145294728

Start: 734623

End: 735630

Strand: Reverse

Name: galE [H]

Synonym: cgR_0676

Alternate gene names: 145294728

Gene position: 735630-734623 (Counterclockwise)

Preceding gene: 145294729

Following gene: 145294721

Centisome position: 22.2

GC content: 49.31

Gene sequence:

>1008_bases
ATGGATCTGGTAAAAGGCCCTGTGCTGGTCACTGGTGGCACGGGTTTCATTGGTAGCCATACTGTTGTTGAGCTTCTCAA
TGCCGGTAAACAAGTAGTTGTCATTGATGATCTTTCCAACAGCACCATTGATGTGCTCGCCTCAATTGAGGAAATCACCG
GTTCTAAACCACCTTTAGAAATCGGTGATATCCGAGATCGTGCATTCGTTGACTCGGTGCTTGCTCAATATCAGCCAAGC
GCGGCAATACATTTTGCTGCAAAAAAAGCTGTCGGCGAATCTGTTGAGCAACCAACGATGTACCTCAACATCAATATTGG
CGGCACCGCGACGTTACTAGATGCGCTTCACCATGCGGGAGTCCGCGACATCGTATTTTCTTCATCATGTTCTGTGCATG
GTGAAACCACTCACTCACCTTTAAATGAGGACTCTCCTACACAACCGGCTAACCCATATGCTTTCACCAAGCTCACCGGC
GAGAAAATGCTGTCCCAGTTGGTTGAAGCTGATGAATCGTGGTCAGCGATTTCGCTTCGCTACTTCAATCCAATTGGTGC
TCATCCCTCCGGAAAACTAGGTGAATCAGGCCTGGGGCGGCCACGCAATATTATGCCATGGCTTCTTGATGTTGCTGCGG
GTCGCAAGCAATCATTGGAAGTTTTCGGTGACGATTGGCCGACTCCTGATGGCACGTGCATCAGGGATTATCTTCATGTT
GTGGATGTGGCTCGAGTCCATGTCCGTGCACTTGAGCATTTCAAAACAGGCCAGGCAGAAGTTTTTAACATCGGAACCGG
CGTTGGTACCAGTGTGCTTGAACTGATCAACACAATGGAAGAAGCCACCGGTCGAGAAATCCCTTATGAGATTTCTGCCC
GCCGTTCTGGAGATGTTTCTGCTCTAGTTGCCGACGCTCAACGTGTAGCTACGCAATGGGGTTGGGTTCCAGAGTTTAGC
GTCTTTCAAATGTGCGCTGACGCCTGGCGTTTTGATCAGAAAAAGTAG

Upstream 100 bases:

>100_bases
TACGCGCTGTAGCATTCCCACTTCTTGCTGGCATCATCATGTTTTTGGCTTCGGTTTTTGCTTTGGCTCTCTACGCTGCG
ATTTTCTTCGGAGGTTACCA

Downstream 100 bases:

>100_bases
GGTTAATCGCTCCTACATAAGAGTTTGGTTCTTCAACGGTGTTACCAGCCAGGTCTTTTGTTGCTGGAGTGCTATCGCCT
GGCACCAGTGATGGCACTGA

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDLVKGPVLVTGGTGFIGSHTVVELLNAGKQVVVIDDLSNSTIDVLASIEEITGSKPPLEIGDIRDRAFVDSVLAQYQPS
AAIHFAAKKAVGESVEQPTMYLNINIGGTATLLDALHHAGVRDIVFSSSCSVHGETTHSPLNEDSPTQPANPYAFTKLTG
EKMLSQLVEADESWSAISLRYFNPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTCIRDYLHV
VDVARVHVRALEHFKTGQAEVFNIGTGVGTSVLELINTMEEATGREIPYEISARRSGDVSALVADAQRVATQWGWVPEFS
VFQMCADAWRFDQKK

Sequences:

>Translated_335_residues
MDLVKGPVLVTGGTGFIGSHTVVELLNAGKQVVVIDDLSNSTIDVLASIEEITGSKPPLEIGDIRDRAFVDSVLAQYQPS
AAIHFAAKKAVGESVEQPTMYLNINIGGTATLLDALHHAGVRDIVFSSSCSVHGETTHSPLNEDSPTQPANPYAFTKLTG
EKMLSQLVEADESWSAISLRYFNPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTCIRDYLHV
VDVARVHVRALEHFKTGQAEVFNIGTGVGTSVLELINTMEEATGREIPYEISARRSGDVSALVADAQRVATQWGWVPEFS
VFQMCADAWRFDQKK
>Mature_335_residues
MDLVKGPVLVTGGTGFIGSHTVVELLNAGKQVVVIDDLSNSTIDVLASIEEITGSKPPLEIGDIRDRAFVDSVLAQYQPS
AAIHFAAKKAVGESVEQPTMYLNINIGGTATLLDALHHAGVRDIVFSSSCSVHGETTHSPLNEDSPTQPANPYAFTKLTG
EKMLSQLVEADESWSAISLRYFNPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTCIRDYLHV
VDVARVHVRALEHFKTGQAEVFNIGTGVGTSVLELINTMEEATGREIPYEISARRSGDVSALVADAQRVATQWGWVPEFS
VFQMCADAWRFDQKK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=335, Percent_Identity=44.7761194029851, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI56118217, Length=335, Percent_Identity=44.7761194029851, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI189083684, Length=335, Percent_Identity=44.7761194029851, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI7657641, Length=269, Percent_Identity=28.2527881040892, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786974, Length=329, Percent_Identity=43.161094224924, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI48994969, Length=345, Percent_Identity=26.3768115942029, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788353, Length=341, Percent_Identity=26.9794721407625, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788366, Length=357, Percent_Identity=23.249299719888, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=40.117994100295, Blast_Score=263, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=40.0584795321637, Blast_Score=260, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17539422, Length=348, Percent_Identity=24.4252873563218, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI133901786, Length=348, Percent_Identity=24.4252873563218, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI133901788, Length=348, Percent_Identity=24.4252873563218, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17539424, Length=348, Percent_Identity=24.4252873563218, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI133901790, Length=348, Percent_Identity=24.4252873563218, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17507723, Length=350, Percent_Identity=23.1428571428571, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=334, Percent_Identity=43.7125748502994, Blast_Score=287, Evalue=2e-78,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=44.3786982248521, Blast_Score=295, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36239; Mature: 36239

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLVKGPVLVTGGTGFIGSHTVVELLNAGKQVVVIDDLSNSTIDVLASIEEITGSKPPLE
CCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
IGDIRDRAFVDSVLAQYQPSAAIHFAAKKAVGESVEQPTMYLNINIGGTATLLDALHHAG
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCC
VRDIVFSSSCSVHGETTHSPLNEDSPTQPANPYAFTKLTGEKMLSQLVEADESWSAISLR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEEE
YFNPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTCIRDYLHV
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHH
VDVARVHVRALEHFKTGQAEVFNIGTGVGTSVLELINTMEEATGREIPYEISARRSGDVS
HHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHH
ALVADAQRVATQWGWVPEFSVFQMCADAWRFDQKK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDLVKGPVLVTGGTGFIGSHTVVELLNAGKQVVVIDDLSNSTIDVLASIEEITGSKPPLE
CCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
IGDIRDRAFVDSVLAQYQPSAAIHFAAKKAVGESVEQPTMYLNINIGGTATLLDALHHAG
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCC
VRDIVFSSSCSVHGETTHSPLNEDSPTQPANPYAFTKLTGEKMLSQLVEADESWSAISLR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEEE
YFNPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTCIRDYLHV
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHH
VDVARVHVRALEHFKTGQAEVFNIGTGVGTSVLELINTMEEATGREIPYEISARRSGDVS
HHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHH
ALVADAQRVATQWGWVPEFSVFQMCADAWRFDQKK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]