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The map label for this gene is catM [H]

Identifier: 145294539

GI number: 145294539

Start: 546695

End: 547579

Strand: Reverse

Name: catM [H]

Synonym: cgR_0491

Alternate gene names: 145294539

Gene position: 547579-546695 (Counterclockwise)

Preceding gene: 145294544

Following gene: 145294534

Centisome position: 16.52

GC content: 54.24

Gene sequence:

>885_bases
ATGCACCTCAATCAGCTCGAATTTTTCATCACAGTAGCCCAACACGGACAGATCAACCGCGCCGCCGAAGAACTCCTCAT
TTCCCAACCCGCTCTCAGCAGACAGATCTCCGCACTTGAAAAATCCGTCGGAGCTCCACTCTTCGAACGCCATTCCCGCG
GTGTCTCCCTCACAAAGGCCGGAGAAATCCTCCACGAAGAAGCCCTCCGAACGCTTAGCAGGATGCAATCAGTAGTCGAT
GAAATCCAATCCGGAGAGCACCTCATCACCAGCATCAACATCGGAGTTCCCCCTGGAATCCCCATCGACTGGTTGCGCTG
CCAACTCATCGATTTAGGCCCCGAGACCCGCATTTCACTGATCGAATCCCCCACCGATGATCAGCTAAAACTTCTTAAAC
AACGCGAACTCGACATCGCCCTTTGTCGACGCCAAAGCGAGGCCTTTGCCACCACACTTGTCCACGAACAAGAACTGGGA
ATCGTCGTCCGAAAAAACTCCGAACTGCACCAAAAAGTCGCAGGAAAAGACAATGCCACACTCTTCGATCTTGAAGGGCT
TCGAGTCCTCGCGCACTCCCGCGGCGAAGTAAGAATTCAGGAAGAAATCCTCAAAAACGCCATGCTCGCCGCAGGAGTTA
ATGCCACGTGGATCTTCCGAAAATTTGGGCAATATAGCTCACTGATCGCCGACCTTGTCCAGGCCGATGTCGCACTCACA
ACAGAGGAATCCGCCCGCACCAACTTCCCCAGCTGGCAATGGGTCCCCATCGAAGGCGAAGACGCCTCCGGAAATGACCT
TGTTGTTCGCACCTGGATCACCTGGAACCCCCAACCCACCCCCGCGGTGAAGGCCCTGATCCAGAAGTTTATTGACGGAA
ACTGA

Upstream 100 bases:

>100_bases
CCTTTCCCTGAACTCTAAGCAATTGTGACCTATAGTACAAATGCATAAAAGTTAACCATGATATCCATCTCTTGCATACC
AGTAGAAAGGTTTAGCCCAC

Downstream 100 bases:

>100_bases
GTTCTAAACAGCCGCCATGAGCTCATCCGCATAGCGGTGGGCATCTGGTGTGGAAATGACAATGCGATCGATGCTGATAT
TCTCCAGCTCAATGACCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Cat operon transcriptional regulator [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MHLNQLEFFITVAQHGQINRAAEELLISQPALSRQISALEKSVGAPLFERHSRGVSLTKAGEILHEEALRTLSRMQSVVD
EIQSGEHLITSINIGVPPGIPIDWLRCQLIDLGPETRISLIESPTDDQLKLLKQRELDIALCRRQSEAFATTLVHEQELG
IVVRKNSELHQKVAGKDNATLFDLEGLRVLAHSRGEVRIQEEILKNAMLAAGVNATWIFRKFGQYSSLIADLVQADVALT
TEESARTNFPSWQWVPIEGEDASGNDLVVRTWITWNPQPTPAVKALIQKFIDGN

Sequences:

>Translated_294_residues
MHLNQLEFFITVAQHGQINRAAEELLISQPALSRQISALEKSVGAPLFERHSRGVSLTKAGEILHEEALRTLSRMQSVVD
EIQSGEHLITSINIGVPPGIPIDWLRCQLIDLGPETRISLIESPTDDQLKLLKQRELDIALCRRQSEAFATTLVHEQELG
IVVRKNSELHQKVAGKDNATLFDLEGLRVLAHSRGEVRIQEEILKNAMLAAGVNATWIFRKFGQYSSLIADLVQADVALT
TEESARTNFPSWQWVPIEGEDASGNDLVVRTWITWNPQPTPAVKALIQKFIDGN
>Mature_294_residues
MHLNQLEFFITVAQHGQINRAAEELLISQPALSRQISALEKSVGAPLFERHSRGVSLTKAGEILHEEALRTLSRMQSVVD
EIQSGEHLITSINIGVPPGIPIDWLRCQLIDLGPETRISLIESPTDDQLKLLKQRELDIALCRRQSEAFATTLVHEQELG
IVVRKNSELHQKVAGKDNATLFDLEGLRVLAHSRGEVRIQEEILKNAMLAAGVNATWIFRKFGQYSSLIADLVQADVALT
TEESARTNFPSWQWVPIEGEDASGNDLVVRTWITWNPQPTPAVKALIQKFIDGN

Specific function: Positively regulates the expression of catA, catBCIJFD and benPK in response to cis,cis-muconate. It binds to the catB- catM intercistronic region, to a specific sequence upstream of catA and to the benPK promoter region. Can also repress pca genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=153, Percent_Identity=36.6013071895425, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI157672245, Length=163, Percent_Identity=35.5828220858896, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367136, Length=168, Percent_Identity=37.5, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790399, Length=198, Percent_Identity=29.7979797979798, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87081904, Length=180, Percent_Identity=32.7777777777778, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=32.1678321678322, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787879, Length=286, Percent_Identity=26.5734265734266, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788297, Length=153, Percent_Identity=32.0261437908497, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082184, Length=225, Percent_Identity=25.7777777777778, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32787; Mature: 32787

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLNQLEFFITVAQHGQINRAAEELLISQPALSRQISALEKSVGAPLFERHSRGVSLTKA
CCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
GEILHEEALRTLSRMQSVVDEIQSGEHLITSINIGVPPGIPIDWLRCQLIDLGPETRISL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHEEEEEECCCCCEEEE
IESPTDDQLKLLKQRELDIALCRRQSEAFATTLVHEQELGIVVRKNSELHQKVAGKDNAT
ECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCE
LFDLEGLRVLAHSRGEVRIQEEILKNAMLAAGVNATWIFRKFGQYSSLIADLVQADVALT
EEECCCCEEECCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEE
TEESARTNFPSWQWVPIEGEDASGNDLVVRTWITWNPQPTPAVKALIQKFIDGN
CCHHHCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MHLNQLEFFITVAQHGQINRAAEELLISQPALSRQISALEKSVGAPLFERHSRGVSLTKA
CCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
GEILHEEALRTLSRMQSVVDEIQSGEHLITSINIGVPPGIPIDWLRCQLIDLGPETRISL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHEEEEEECCCCCEEEE
IESPTDDQLKLLKQRELDIALCRRQSEAFATTLVHEQELGIVVRKNSELHQKVAGKDNAT
ECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCE
LFDLEGLRVLAHSRGEVRIQEEILKNAMLAAGVNATWIFRKFGQYSSLIADLVQADVALT
EEECCCCEEECCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEE
TEESARTNFPSWQWVPIEGEDASGNDLVVRTWITWNPQPTPAVKALIQKFIDGN
CCHHHCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2793826; 7592340; 11932465; 12620848 [H]