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The map label for this gene is fabD [H]

Identifier: 145294397

GI number: 145294397

Start: 388249

End: 389175

Strand: Reverse

Name: fabD [H]

Synonym: cgR_0352

Alternate gene names: 145294397

Gene position: 389175-388249 (Counterclockwise)

Preceding gene: 145294398

Following gene: 145294395

Centisome position: 11.74

GC content: 51.02

Gene sequence:

>927_bases
ATGGTTCTCACACTGCTTTTTGGTGGCCAAGGTAGCCAAAAAATTGGCATGCTGCATTCCTGGTTAGCACTGGAAAAAGT
CAAAGAATGCGTCACCATTGCAAGTGCTGTATTGGGCGAGGATGCGCTTTTGATTGATCGGGAAGAGTCACTTGCCAACA
CCCGTGGGGTGCAGCTTTCTTTATTAATCCTGCAATCTGGCATGGCTTTGGAACTTCAACAACGTGGGCTGGTGCCACAA
TTTGGAGCAGGGCATTCTTTGGGGGCATGGAGCGCAGCTGTTGCGGCTGGTTCACTGAACTTTGAGGATGCTGTCCGGTT
AGTTGATATCCGTGCTCGCACCATGCACGATGCTGCACCTGGTGATTACGGTATGTCAGCGGTGATCGGGCTTAACCGAG
TGGCGTTGTCTAAAGCGGTGGATTCCTTGCGTGCAGAAGGCGAAGAGATCTGGCTTTCCAATCTAAATTCAGCAGAGCAA
TCCACGGTCTCTGGTTCGCATGCAGCGTTAGAGAAGATGGAAGCAATTGGTGCAGGCCTCGGAGCACGGAAAATTAAGCG
GCTTAAAGTTGCAGTTCCTGCACATAGTGAGTTGATGTCGCCTGCGCGGTTCGCAGTTGCAAAAGCAATGGAAGATATAA
CCGTAGAATCACCCCGATATCCGCTGCTTGCTAACTCTTCCAGCCGAATGATCCGAACTGGACCACAGGTAAAAAATGAC
CTAATAGAAGTAATCGATCAACCAGTGCAGTGGGGTCCTGGTATCGCTTCACTTGCAGAACGCGGAGTGACTGACTGGAT
ACAGGTCTCCCCCGGCAACACTTTGATTGGGCTACTTCGGGGGTTGGACACCGACTACACCGGATGGTGCGTAGATAATG
TCGGCGTGGAGGAAACTATTGCGAAGGTGGGCGTCGAAAAGCTTTAA

Upstream 100 bases:

>100_bases
TTAGTGAGCTTGAGCGCGCTATGTCGTATTCACCAATGCCTTCGATGATGCTTCGCACACATCAAGGTCCGGAACTCAGC
AACATCATTTGGAGGTAGTC

Downstream 100 bases:

>100_bases
TGGGGCGTGCGAGCAGCATGCGCAAGGTCGCGTTGACCTGCGTCGGCAGCGGGCGCCCTGCCATCTTAACCAAGCCGATC
TCTCTGGTGGCTAACTCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MVLTLLFGGQGSQKIGMLHSWLALEKVKECVTIASAVLGEDALLIDREESLANTRGVQLSLLILQSGMALELQQRGLVPQ
FGAGHSLGAWSAAVAAGSLNFEDAVRLVDIRARTMHDAAPGDYGMSAVIGLNRVALSKAVDSLRAEGEEIWLSNLNSAEQ
STVSGSHAALEKMEAIGAGLGARKIKRLKVAVPAHSELMSPARFAVAKAMEDITVESPRYPLLANSSSRMIRTGPQVKND
LIEVIDQPVQWGPGIASLAERGVTDWIQVSPGNTLIGLLRGLDTDYTGWCVDNVGVEETIAKVGVEKL

Sequences:

>Translated_308_residues
MVLTLLFGGQGSQKIGMLHSWLALEKVKECVTIASAVLGEDALLIDREESLANTRGVQLSLLILQSGMALELQQRGLVPQ
FGAGHSLGAWSAAVAAGSLNFEDAVRLVDIRARTMHDAAPGDYGMSAVIGLNRVALSKAVDSLRAEGEEIWLSNLNSAEQ
STVSGSHAALEKMEAIGAGLGARKIKRLKVAVPAHSELMSPARFAVAKAMEDITVESPRYPLLANSSSRMIRTGPQVKND
LIEVIDQPVQWGPGIASLAERGVTDWIQVSPGNTLIGLLRGLDTDYTGWCVDNVGVEETIAKVGVEKL
>Mature_308_residues
MVLTLLFGGQGSQKIGMLHSWLALEKVKECVTIASAVLGEDALLIDREESLANTRGVQLSLLILQSGMALELQQRGLVPQ
FGAGHSLGAWSAAVAAGSLNFEDAVRLVDIRARTMHDAAPGDYGMSAVIGLNRVALSKAVDSLRAEGEEIWLSNLNSAEQ
STVSGSHAALEKMEAIGAGLGARKIKRLKVAVPAHSELMSPARFAVAKAMEDITVESPRYPLLANSSSRMIRTGPQVKND
LIEVIDQPVQWGPGIASLAERGVTDWIQVSPGNTLIGLLRGLDTDYTGWCVDNVGVEETIAKVGVEKL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1787334, Length=289, Percent_Identity=35.9861591695502, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71984332, Length=266, Percent_Identity=26.6917293233083, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17550940, Length=206, Percent_Identity=23.7864077669903, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665753, Length=305, Percent_Identity=27.5409836065574, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32743; Mature: 32743

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLTLLFGGQGSQKIGMLHSWLALEKVKECVTIASAVLGEDALLIDREESLANTRGVQLS
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCEEE
LLILQSGMALELQQRGLVPQFGAGHSLGAWSAAVAAGSLNFEDAVRLVDIRARTMHDAAP
EEEECCCCEEEHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
GDYGMSAVIGLNRVALSKAVDSLRAEGEEIWLSNLNSAEQSTVSGSHAALEKMEAIGAGL
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCC
GARKIKRLKVAVPAHSELMSPARFAVAKAMEDITVESPRYPLLANSSSRMIRTGPQVKND
CHHHHHHEEEECCCHHHHHCHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEECCCHHHHH
LIEVIDQPVQWGPGIASLAERGVTDWIQVSPGNTLIGLLRGLDTDYTGWCVDNVGVEETI
HHHHHCCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCCEEECCCCHHHHH
AKVGVEKL
HHHHHCCC
>Mature Secondary Structure
MVLTLLFGGQGSQKIGMLHSWLALEKVKECVTIASAVLGEDALLIDREESLANTRGVQLS
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCEEE
LLILQSGMALELQQRGLVPQFGAGHSLGAWSAAVAAGSLNFEDAVRLVDIRARTMHDAAP
EEEECCCCEEEHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
GDYGMSAVIGLNRVALSKAVDSLRAEGEEIWLSNLNSAEQSTVSGSHAALEKMEAIGAGL
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCC
GARKIKRLKVAVPAHSELMSPARFAVAKAMEDITVESPRYPLLANSSSRMIRTGPQVKND
CHHHHHHEEEECCCHHHHHCHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEECCCHHHHH
LIEVIDQPVQWGPGIASLAERGVTDWIQVSPGNTLIGLLRGLDTDYTGWCVDNVGVEETI
HHHHHCCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCCEEECCCCHHHHH
AKVGVEKL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]