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The map label for this gene is moaE2 [H]

Identifier: 145294333

GI number: 145294333

Start: 315820

End: 316278

Strand: Reverse

Name: moaE2 [H]

Synonym: cgR_0288

Alternate gene names: 145294333

Gene position: 316278-315820 (Counterclockwise)

Preceding gene: 145294334

Following gene: 145294332

Centisome position: 9.54

GC content: 67.1

Gene sequence:

>459_bases
ATGAACACTGATCCCGCTTACGTCGCCGAACAAACCGGCAAACTCATCGACGCTTTCCTCACCACCGACCCCCTCGAACC
GCTACTCGACGCCGCCAAAACCGACGTCTGCACCGAGGCGATGGGCGCGCTGGTCACCTTCGAAGGCATCGTCCGCGACC
ACGACGGCGGCGCCCGCGTGACCTCCCTGACCTACACCGCGCATCCCACCGCGCCGCAGGTCCTTTCTGCTGTCGCGGAC
TCTATCGTTGAAAAACACCCGCGCACCCGCCTCTGGACCGCGCACCGCACCGGCGCCTTGAAAATCCGTGACGCCGCCTT
CCTCGTCGTCGCCGCCTCCGCCCACCGCGCCGACGCCTTCGCCGCCTGCTCCGACCTCGCCGACGCCGTCAAAGCCCAGG
TCCCGATCTGGAAAGAGCAAACGCGCCTCGACGGCTCCACCGATTGGGTCGGCCTGTGA

Upstream 100 bases:

>100_bases
TTCATCATGGCACTGCCCGGCTCCACGGGTGCGGCGCGCGATGCCACGGCTGTCCTCGACCCGCTCATTGATCACATCAC
TGGAACTCTGCAAGGCCACC

Downstream 100 bases:

>100_bases
AAAACCTCGACATCGCCCGCTACCGCCGCCAAATTATGCTCGGCGAAATCGGCCAGCAAAAACAACAATCGCTTTTCGAC
GCTAAGGTCTCCGTCATCGG

Product: hypothetical protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E 2; Molybdopterin-converting factor large subunit 2; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MNTDPAYVAEQTGKLIDAFLTTDPLEPLLDAAKTDVCTEAMGALVTFEGIVRDHDGGARVTSLTYTAHPTAPQVLSAVAD
SIVEKHPRTRLWTAHRTGALKIRDAAFLVVAASAHRADAFAACSDLADAVKAQVPIWKEQTRLDGSTDWVGL

Sequences:

>Translated_152_residues
MNTDPAYVAEQTGKLIDAFLTTDPLEPLLDAAKTDVCTEAMGALVTFEGIVRDHDGGARVTSLTYTAHPTAPQVLSAVAD
SIVEKHPRTRLWTAHRTGALKIRDAAFLVVAASAHRADAFAACSDLADAVKAQVPIWKEQTRLDGSTDWVGL
>Mature_152_residues
MNTDPAYVAEQTGKLIDAFLTTDPLEPLLDAAKTDVCTEAMGALVTFEGIVRDHDGGARVTSLTYTAHPTAPQVLSAVAD
SIVEKHPRTRLWTAHRTGALKIRDAAFLVVAASAHRADAFAACSDLADAVKAQVPIWKEQTRLDGSTDWVGL

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=124, Percent_Identity=33.0645161290323, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787003, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16240; Mature: 16240

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDPAYVAEQTGKLIDAFLTTDPLEPLLDAAKTDVCTEAMGALVTFEGIVRDHDGGARV
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEE
TSLTYTAHPTAPQVLSAVADSIVEKHPRTRLWTAHRTGALKIRDAAFLVVAASAHRADAF
EEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCEEEEEECCCCCHHHH
AACSDLADAVKAQVPIWKEQTRLDGSTDWVGL
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNTDPAYVAEQTGKLIDAFLTTDPLEPLLDAAKTDVCTEAMGALVTFEGIVRDHDGGARV
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEE
TSLTYTAHPTAPQVLSAVADSIVEKHPRTRLWTAHRTGALKIRDAAFLVVAASAHRADAF
EEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCEEEEEECCCCCHHHH
AACSDLADAVKAQVPIWKEQTRLDGSTDWVGL
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]