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The map label for this gene is mntH [H]

Identifier: 145294201

GI number: 145294201

Start: 173840

End: 175054

Strand: Reverse

Name: mntH [H]

Synonym: cgR_0158

Alternate gene names: 145294201

Gene position: 175054-173840 (Counterclockwise)

Preceding gene: 145294202

Following gene: 145294200

Centisome position: 5.28

GC content: 65.84

Gene sequence:

>1215_bases
GTGAGCCGGCAGCCTCTGCCCTGGCTGCTGGGCCCGGCCTTCGTGGCTGCGGTGGCCTATGTGGACCCGGGTAACGTCGC
GGCGAATATCACCGCCGGGGCGCAGTACGGGTACCTGCTGGTGTGGGTGCTGGTGGTCGCCAATGTCATGGCGATGCTCG
TGCAGTACCTCTCGGCCAAACTCGGGTTGGTCACCGGTTATTCCCTGCCGGAGTTGCTGGGGCAACGGCTACCGCGGGGA
CGGCGCTTGATGTTCTGGGCGCAAGCAGAGACGGTGGCCGCGGCCACGGACCTAGCCGAAGTGATCGGCGGAGCGATCGC
CCTCCACATTCTCTTCGGCCTCCCCTTGCTGATAGGGGGCCTGCTCATCGGGCTGGTCTCGATGCTGCTGCTGGCCATCC
AATCCAGGCACGGTCAGCATCCCTTCGAGTTCGTCATCGTAGGTCTGCTGGTAATCATCACCGCCGGCTTCCTCACGGGC
ATGTTCATCGGCACTGTCTCCTGGGGCGAGGCCCTGGCTGGGGTTATCCCGCGCTTTGAGGGGACCCCGACGGTGGTGCT
GGCCGCGAGCATGCTCGGAGCCACCGTGATGCCCCATGCCATCTATGCCCACTCCTCCCTCGCCCGAGACCGCCACGGTG
ACACCATCGCGCCCGAGGCATTGCCGCGCCTGCTCCGTGTCACCCGGTGGGATGTTCTCCTGTCGCTGCTGGTGGCCGGG
TCGGTCAATATCGCGATGCTGTTGTTGGCGGCCGGCAACTTGAACGGGATTCCTGGCACCGACAGCATCGAAGGGGCCCA
CGCGGTGATCACCGACACGCTGGGCCCGGTAGTCGGAGTGGCCTTCGGTGTCGGTTTGCTGGCTTCCGGGCTGGCGTCCA
CCTCGGTGGGCTGCTACGCCGGATCCACGATCATGGGCGGATTGTTGCACCGGCAGATCCCGCAGGTGGTGCGGCGAGCG
GTCACCCTGATCCCGGCCTTAATCGTGATCGCCGCCGGGGTGGAGCCGACGTGGGCGCTGGTGCTCTCCCAGGTGGTCCT
CAGCCTGGGTATCCCCTTCGCCCTGATCCCGCTGGTGGTGTTGAGCAGTGATCAAACCCTCATGGGTGGTTTCGCCATCC
GGGTTCCTCTGCAGGTGGCGTCCTGGGTGGTGGTCGCGTTGATTGTGTCGCTGAATCTCGCCTTGATCGGACTGCTGGTC
ACCGGTCGGGGCTGA

Upstream 100 bases:

>100_bases
CCCCGAGACTATAAGTTCGTGTAACTTAACTTTTATGAAACTCAGGGGCGCCTGGGGCGACTCGGACCAAGCGGTACAAA
GAGTACCGGGTGGGCGACGG

Downstream 100 bases:

>100_bases
CCGGCTGTGGTCTTCGGTAGCGTGAGTCCATGGACCTGAGTGAGATCACGCCGGTAGCCCAGGACTACCTCAAGGTGATC
TGGGCGGCCACCGAGTGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: BRAMP [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSRQPLPWLLGPAFVAAVAYVDPGNVAANITAGAQYGYLLVWVLVVANVMAMLVQYLSAKLGLVTGYSLPELLGQRLPRG
RRLMFWAQAETVAAATDLAEVIGGAIALHILFGLPLLIGGLLIGLVSMLLLAIQSRHGQHPFEFVIVGLLVIITAGFLTG
MFIGTVSWGEALAGVIPRFEGTPTVVLAASMLGATVMPHAIYAHSSLARDRHGDTIAPEALPRLLRVTRWDVLLSLLVAG
SVNIAMLLLAAGNLNGIPGTDSIEGAHAVITDTLGPVVGVAFGVGLLASGLASTSVGCYAGSTIMGGLLHRQIPQVVRRA
VTLIPALIVIAAGVEPTWALVLSQVVLSLGIPFALIPLVVLSSDQTLMGGFAIRVPLQVASWVVVALIVSLNLALIGLLV
TGRG

Sequences:

>Translated_404_residues
MSRQPLPWLLGPAFVAAVAYVDPGNVAANITAGAQYGYLLVWVLVVANVMAMLVQYLSAKLGLVTGYSLPELLGQRLPRG
RRLMFWAQAETVAAATDLAEVIGGAIALHILFGLPLLIGGLLIGLVSMLLLAIQSRHGQHPFEFVIVGLLVIITAGFLTG
MFIGTVSWGEALAGVIPRFEGTPTVVLAASMLGATVMPHAIYAHSSLARDRHGDTIAPEALPRLLRVTRWDVLLSLLVAG
SVNIAMLLLAAGNLNGIPGTDSIEGAHAVITDTLGPVVGVAFGVGLLASGLASTSVGCYAGSTIMGGLLHRQIPQVVRRA
VTLIPALIVIAAGVEPTWALVLSQVVLSLGIPFALIPLVVLSSDQTLMGGFAIRVPLQVASWVVVALIVSLNLALIGLLV
TGRG
>Mature_403_residues
SRQPLPWLLGPAFVAAVAYVDPGNVAANITAGAQYGYLLVWVLVVANVMAMLVQYLSAKLGLVTGYSLPELLGQRLPRGR
RLMFWAQAETVAAATDLAEVIGGAIALHILFGLPLLIGGLLIGLVSMLLLAIQSRHGQHPFEFVIVGLLVIITAGFLTGM
FIGTVSWGEALAGVIPRFEGTPTVVLAASMLGATVMPHAIYAHSSLARDRHGDTIAPEALPRLLRVTRWDVLLSLLVAGS
VNIAMLLLAAGNLNGIPGTDSIEGAHAVITDTLGPVVGVAFGVGLLASGLASTSVGCYAGSTIMGGLLHRQIPQVVRRAV
TLIPALIVIAAGVEPTWALVLSQVVLSLGIPFALIPLVVLSSDQTLMGGFAIRVPLQVASWVVVALIVSLNLALIGLLVT
GRG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI295293178, Length=433, Percent_Identity=28.8683602771363, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI295293171, Length=433, Percent_Identity=28.8683602771363, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI295293169, Length=433, Percent_Identity=28.8683602771363, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI295293167, Length=433, Percent_Identity=28.8683602771363, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI295293175, Length=433, Percent_Identity=28.8683602771363, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI295293173, Length=433, Percent_Identity=28.8683602771363, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI10835169, Length=433, Percent_Identity=28.8683602771363, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI109255241, Length=428, Percent_Identity=29.9065420560748, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1788736, Length=391, Percent_Identity=43.7340153452685, Blast_Score=294, Evalue=7e-81,
Organism=Caenorhabditis elegans, GI17569473, Length=414, Percent_Identity=30.1932367149758, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI193210616, Length=431, Percent_Identity=28.538283062645, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71999499, Length=429, Percent_Identity=28.4382284382284, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71993856, Length=204, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323062, Length=395, Percent_Identity=32.6582278481013, Blast_Score=171, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321841, Length=402, Percent_Identity=33.8308457711443, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324450, Length=413, Percent_Identity=27.8450363196126, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24648607, Length=427, Percent_Identity=28.8056206088993, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281362176, Length=427, Percent_Identity=28.8056206088993, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24648609, Length=427, Percent_Identity=28.8056206088993, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI45553443, Length=402, Percent_Identity=29.8507462686567, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005025
- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF03358 FMN_red; PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 41921; Mature: 41790

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQPLPWLLGPAFVAAVAYVDPGNVAANITAGAQYGYLLVWVLVVANVMAMLVQYLSAK
CCCCCCCHHHHHHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLVTGYSLPELLGQRLPRGRRLMFWAQAETVAAATDLAEVIGGAIALHILFGLPLLIGG
HHHHCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIGLVSMLLLAIQSRHGQHPFEFVIVGLLVIITAGFLTGMFIGTVSWGEALAGVIPRFE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTPTVVLAASMLGATVMPHAIYAHSSLARDRHGDTIAPEALPRLLRVTRWDVLLSLLVAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SVNIAMLLLAAGNLNGIPGTDSIEGAHAVITDTLGPVVGVAFGVGLLASGLASTSVGCYA
CHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
GSTIMGGLLHRQIPQVVRRAVTLIPALIVIAAGVEPTWALVLSQVVLSLGIPFALIPLVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
LSSDQTLMGGFAIRVPLQVASWVVVALIVSLNLALIGLLVTGRG
HCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRQPLPWLLGPAFVAAVAYVDPGNVAANITAGAQYGYLLVWVLVVANVMAMLVQYLSAK
CCCCCCHHHHHHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLVTGYSLPELLGQRLPRGRRLMFWAQAETVAAATDLAEVIGGAIALHILFGLPLLIGG
HHHHCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIGLVSMLLLAIQSRHGQHPFEFVIVGLLVIITAGFLTGMFIGTVSWGEALAGVIPRFE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTPTVVLAASMLGATVMPHAIYAHSSLARDRHGDTIAPEALPRLLRVTRWDVLLSLLVAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SVNIAMLLLAAGNLNGIPGTDSIEGAHAVITDTLGPVVGVAFGVGLLASGLASTSVGCYA
CHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
GSTIMGGLLHRQIPQVVRRAVTLIPALIVIAAGVEPTWALVLSQVVLSLGIPFALIPLVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
LSSDQTLMGGFAIRVPLQVASWVVVALIVSLNLALIGLLVTGRG
HCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972; 9632246 [H]