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The map label for this gene is cmtR [H]

Identifier: 145294199

GI number: 145294199

Start: 172573

End: 172932

Strand: Reverse

Name: cmtR [H]

Synonym: cgR_0156

Alternate gene names: 145294199

Gene position: 172932-172573 (Counterclockwise)

Preceding gene: 145294200

Following gene: 145294198

Centisome position: 5.22

GC content: 64.72

Gene sequence:

>360_bases
ATGCTGACTATTGCTTCCTGTCTCGATGTGATGAACCGGTTAGGCCGTGCCATGGCCGATCCCACCCGGTCCCGGATCCT
GTTGTCTCTGCTGGAGGCGCCCGGCTATCCCGCGCAACTGGCTCGGGAGCTGGAACTGACGCGCCCGAATGTGTCGAACC
ATCTCGCCTGCCTACGCGACTGCGGCATCATCGTTGCCGAACCGGAGGGCCGGCAGACTCGCTACGAAATCGTCGACGCC
CACCTCGCCCAGGCGCTCAACGCGTTGCTGGACGTCACGCTCGCGGTGGATGAGCACGCTCCCTGTCTCGACTCGGGCTG
TGACGTGCCCGGTTGTGTCACCGGGCAGGAGGGCATGTGA

Upstream 100 bases:

>100_bases
CGTTTGCGATGCGTGACGTTCGGAGCTGATGCACATATTTCCTGGCCCATCCTCCGGGGGCGGGCAAGGATTGTTCAGTG
TCTGCTGTATAGTTAAGTGC

Downstream 100 bases:

>100_bases
TGGTCTCCGGCTTGCTGTCGGCGATTGGCCTGTTCCTCGCCACGAACATTGACGACATCATCGTGCTTTCGCTGTTCTTC
GCCCGCGGTGCGGGACAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MLTIASCLDVMNRLGRAMADPTRSRILLSLLEAPGYPAQLARELELTRPNVSNHLACLRDCGIIVAEPEGRQTRYEIVDA
HLAQALNALLDVTLAVDEHAPCLDSGCDVPGCVTGQEGM

Sequences:

>Translated_119_residues
MLTIASCLDVMNRLGRAMADPTRSRILLSLLEAPGYPAQLARELELTRPNVSNHLACLRDCGIIVAEPEGRQTRYEIVDA
HLAQALNALLDVTLAVDEHAPCLDSGCDVPGCVTGQEGM
>Mature_119_residues
MLTIASCLDVMNRLGRAMADPTRSRILLSLLEAPGYPAQLARELELTRPNVSNHLACLRDCGIIVAEPEGRQTRYEIVDA
HLAQALNALLDVTLAVDEHAPCLDSGCDVPGCVTGQEGM

Specific function: Metal-responsive transcriptional repressor for the cmt operon. Binding of cadmium or lead causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12797; Mature: 12797

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIASCLDVMNRLGRAMADPTRSRILLSLLEAPGYPAQLARELELTRPNVSNHLACLRD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHH
CGIIVAEPEGRQTRYEIVDAHLAQALNALLDVTLAVDEHAPCLDSGCDVPGCVTGQEGM
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTIASCLDVMNRLGRAMADPTRSRILLSLLEAPGYPAQLARELELTRPNVSNHLACLRD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHH
CGIIVAEPEGRQTRYEIVDAHLAQALNALLDVTLAVDEHAPCLDSGCDVPGCVTGQEGM
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]