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The map label for this gene is yrkH [H]

Identifier: 145294113

GI number: 145294113

Start: 82789

End: 84159

Strand: Direct

Name: yrkH [H]

Synonym: cgR_0071

Alternate gene names: 145294113

Gene position: 82789-84159 (Clockwise)

Preceding gene: 145294112

Following gene: 145294117

Centisome position: 2.5

GC content: 51.5

Gene sequence:

>1371_bases
GTGCTTATTGAACGCATCTACGACGAAGACCTTGCGCAGGCCAGCTATTTCATTGGCTGCCAAGCCCACAACACCGCAGT
CGTGGTTGATCCGCGTCGCGATATTGCCATCTATCTGGACATGGCCAAGAAAAACGGAATGGAGATTGTTGGAGTTACCG
AAACCCATATCCATGCGGACTATTTGTCAGGAACACGCGAGTTAGCAGCAGCAACTAATGCCACTATGTACGTTTCAGGG
GAGGGTGGCGCCGATTGGCAGTATGAATTTGACGCCGAGCGACTTTATGACGGCGGTGAGATTCGCCTTGGAAACCTGGT
GCTCACAGCAGTTCACACCCCAGGCCACACTCCGGAACATTTGTCGTTCCTGCTGAAGGATGGTGCGTTCGCGGACGAGC
CAGGATTCATGCTCACTGGCGATTTCGTTTTCGCCGGTGATCTTGGCCGACCAGATTTGCTTGATCAAGCAGCTGGTGGA
GTAGACACTCGTTTTGAGGGAGCTCGCCAAATGTTCAAGAGCTTGAAGGAAAAGTTCTTGACACTGCCGGATCACATCCA
GATCTTCCCAGGTCATGGTTCCGGTTCTGCGTGTGGCAAAGCATTGGGTTCGGTTCCTTCAACAACACTTGGATATGAAC
GTCAATTTGCGTGGTGGGGAAAGTATCTGGAGGCAGATGATGAACAAGGATTCATCGATGAGCTTCTGGAAGGCCAACCT
GATGCTCCTGCTTATTTCGGCAGGATGAAGAGACAGAATAGGCAAGGACCTGCAATTATGGGCGCTCGCGAGCCATTGCC
ACAGCTGGAAGCTTCTGATCTGCACGACGTCATTGTTGTTGATACCCGCTCAGCCGATGAAGTTCACCAGGGCACTGTAG
CTGGTGCAGTGAATATTCCTGCGGGAAATTCGATGGCGAAATTTGGCTCGTGGACCGTTGATCCCGAGAAGGATTCCCGA
GCTTTGGTTCTTCTCGCGGCAAGCCAAATTGGTGCCATGGAGATGTGGGATCATTTAGTTCGGGTGGGAATCGATAATGT
TGCAGGATTTGTCACCAACTTTGATGGCGTGGATCTGGTTGCACCGCAAACTGTGTCCCCAGATGAGTTGGATAAATTTG
AATATGATCTGCTTCTTGATGTCCGCAACCGCAGTGAAGTCGAAGAAGGCTACATCCCGGGAGCACTCCATATTAATGGT
GCATCCGTGCTGTGGAATCTGGAGAAACTGCCACGTGACGGAAAGATCGTGAGCTACTGCAAGAGTGGAACACGCAGCTC
CATCGCGGCAAGTACCCTGCGCAACGCTGGTTTTGATGTGGTGGAACTTGAAGGATCCTATGACAATTGGGTCCGGCACA
ACGCACAATAA

Upstream 100 bases:

>100_bases
GAATTAGTGAACCTGCGCTTGAACTATACCCCCTGGGGTATTACTGTAGATCCTCAATACCCTAAGGGGTATCCAATTTT
ACGTTGAGAAGGAGAGCTCA

Downstream 100 bases:

>100_bases
TTAATAGACAAAGGAACCCTCACGAACTGTGAGGGTTCCTTTTTTGGGTTTCGCCGGAGGGAGACGTCGAAAAGCTTATA
AAAGCTCTAAGCCGAGCACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLIERIYDEDLAQASYFIGCQAHNTAVVVDPRRDIAIYLDMAKKNGMEIVGVTETHIHADYLSGTRELAAATNATMYVSG
EGGADWQYEFDAERLYDGGEIRLGNLVLTAVHTPGHTPEHLSFLLKDGAFADEPGFMLTGDFVFAGDLGRPDLLDQAAGG
VDTRFEGARQMFKSLKEKFLTLPDHIQIFPGHGSGSACGKALGSVPSTTLGYERQFAWWGKYLEADDEQGFIDELLEGQP
DAPAYFGRMKRQNRQGPAIMGAREPLPQLEASDLHDVIVVDTRSADEVHQGTVAGAVNIPAGNSMAKFGSWTVDPEKDSR
ALVLLAASQIGAMEMWDHLVRVGIDNVAGFVTNFDGVDLVAPQTVSPDELDKFEYDLLLDVRNRSEVEEGYIPGALHING
ASVLWNLEKLPRDGKIVSYCKSGTRSSIAASTLRNAGFDVVELEGSYDNWVRHNAQ

Sequences:

>Translated_456_residues
MLIERIYDEDLAQASYFIGCQAHNTAVVVDPRRDIAIYLDMAKKNGMEIVGVTETHIHADYLSGTRELAAATNATMYVSG
EGGADWQYEFDAERLYDGGEIRLGNLVLTAVHTPGHTPEHLSFLLKDGAFADEPGFMLTGDFVFAGDLGRPDLLDQAAGG
VDTRFEGARQMFKSLKEKFLTLPDHIQIFPGHGSGSACGKALGSVPSTTLGYERQFAWWGKYLEADDEQGFIDELLEGQP
DAPAYFGRMKRQNRQGPAIMGAREPLPQLEASDLHDVIVVDTRSADEVHQGTVAGAVNIPAGNSMAKFGSWTVDPEKDSR
ALVLLAASQIGAMEMWDHLVRVGIDNVAGFVTNFDGVDLVAPQTVSPDELDKFEYDLLLDVRNRSEVEEGYIPGALHING
ASVLWNLEKLPRDGKIVSYCKSGTRSSIAASTLRNAGFDVVELEGSYDNWVRHNAQ
>Mature_456_residues
MLIERIYDEDLAQASYFIGCQAHNTAVVVDPRRDIAIYLDMAKKNGMEIVGVTETHIHADYLSGTRELAAATNATMYVSG
EGGADWQYEFDAERLYDGGEIRLGNLVLTAVHTPGHTPEHLSFLLKDGAFADEPGFMLTGDFVFAGDLGRPDLLDQAAGG
VDTRFEGARQMFKSLKEKFLTLPDHIQIFPGHGSGSACGKALGSVPSTTLGYERQFAWWGKYLEADDEQGFIDELLEGQP
DAPAYFGRMKRQNRQGPAIMGAREPLPQLEASDLHDVIVVDTRSADEVHQGTVAGAVNIPAGNSMAKFGSWTVDPEKDSR
ALVLLAASQIGAMEMWDHLVRVGIDNVAGFVTNFDGVDLVAPQTVSPDELDKFEYDLLLDVRNRSEVEEGYIPGALHING
ASVLWNLEKLPRDGKIVSYCKSGTRSSIAASTLRNAGFDVVELEGSYDNWVRHNAQ

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=196, Percent_Identity=27.0408163265306, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21703352, Length=205, Percent_Identity=28.780487804878, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI116642887, Length=205, Percent_Identity=28.780487804878, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1787158, Length=220, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538952, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221330176, Length=198, Percent_Identity=26.2626262626263, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 49830; Mature: 49830

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIERIYDEDLAQASYFIGCQAHNTAVVVDPRRDIAIYLDMAKKNGMEIVGVTETHIHAD
CCHHHHHHHHHHHCEEEEEEECCCEEEEEECCCCEEEEEEECCCCCCEEEEEEHHEEEHH
YLSGTRELAAATNATMYVSGEGGADWQYEFDAERLYDGGEIRLGNLVLTAVHTPGHTPEH
HHCCHHHHHHHCCCEEEEECCCCCCCEEECCHHHHCCCCCEEECCEEEEEEECCCCCHHH
LSFLLKDGAFADEPGFMLTGDFVFAGDLGRPDLLDQAAGGVDTRFEGARQMFKSLKEKFL
HHHHHHCCCCCCCCCEEEECCEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
TLPDHIQIFPGHGSGSACGKALGSVPSTTLGYERQFAWWGKYLEADDEQGFIDELLEGQP
CCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
DAPAYFGRMKRQNRQGPAIMGAREPLPQLEASDLHDVIVVDTRSADEVHQGTVAGAVNIP
CCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHCCEEEEEEECC
AGNSMAKFGSWTVDPEKDSRALVLLAASQIGAMEMWDHLVRVGIDNVAGFVTNFDGVDLV
CCCCHHHCCCEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHCCCCCCEEE
APQTVSPDELDKFEYDLLLDVRNRSEVEEGYIPGALHINGASVLWNLEKLPRDGKIVSYC
CCCCCCHHHHHCCCEEEEEEECCCCHHHHCCCCCEEEECCHHEEEEHHHCCCCCCEEHHH
KSGTRSSIAASTLRNAGFDVVELEGSYDNWVRHNAQ
HCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHCCCC
>Mature Secondary Structure
MLIERIYDEDLAQASYFIGCQAHNTAVVVDPRRDIAIYLDMAKKNGMEIVGVTETHIHAD
CCHHHHHHHHHHHCEEEEEEECCCEEEEEECCCCEEEEEEECCCCCCEEEEEEHHEEEHH
YLSGTRELAAATNATMYVSGEGGADWQYEFDAERLYDGGEIRLGNLVLTAVHTPGHTPEH
HHCCHHHHHHHCCCEEEEECCCCCCCEEECCHHHHCCCCCEEECCEEEEEEECCCCCHHH
LSFLLKDGAFADEPGFMLTGDFVFAGDLGRPDLLDQAAGGVDTRFEGARQMFKSLKEKFL
HHHHHHCCCCCCCCCEEEECCEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
TLPDHIQIFPGHGSGSACGKALGSVPSTTLGYERQFAWWGKYLEADDEQGFIDELLEGQP
CCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
DAPAYFGRMKRQNRQGPAIMGAREPLPQLEASDLHDVIVVDTRSADEVHQGTVAGAVNIP
CCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHCCEEEEEEECC
AGNSMAKFGSWTVDPEKDSRALVLLAASQIGAMEMWDHLVRVGIDNVAGFVTNFDGVDLV
CCCCHHHCCCEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHCCCCCCEEE
APQTVSPDELDKFEYDLLLDVRNRSEVEEGYIPGALHINGASVLWNLEKLPRDGKIVSYC
CCCCCCHHHHHCCCEEEEEEECCCCHHHHCCCCCEEEECCHHEEEEHHHCCCCCCEEHHH
KSGTRSSIAASTLRNAGFDVVELEGSYDNWVRHNAQ
HCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]