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The map label for this gene is ftsW [H]

Identifier: 145294099

GI number: 145294099

Start: 64763

End: 66088

Strand: Reverse

Name: ftsW [H]

Synonym: cgR_0057

Alternate gene names: 145294099

Gene position: 66088-64763 (Counterclockwise)

Preceding gene: 145294100

Following gene: 145294098

Centisome position: 1.99

GC content: 54.6

Gene sequence:

>1326_bases
ATGAACACGCTTGAACGATTAAAGCTACGTCGCACGGAAATGTGGCTGCTGATACTTGCCACACTCGTTGTGTCGATCAT
GTTCATCAGCCTCGAGCTGGCCATGGGCAATGAGTTGGGTACCCATATTTTGATGCTGATGGGCGGATACATCGGTATCT
TCATCGTCGCGCACCTAGCCATGGCATGGGTGGCGCCGTTTGCTGATCAGATCATGCTGCCTGTGGTGGCGGTGCTCAAC
GGCATTGGTTTGGTGATGATCTATCGCCTTGATGAGGCCACGGGCTATAGCACGGTCAATAGCCAATTGATGTGGACGGT
TGTTGGCGTCACACTGATGGTGGCTGTGTTGTTGCTGTTGCGTGATTACAAGTCACTCTCGCGTTATTCCTACCTCCTCG
GTGTGGTGGGCATTGTGCTGCTAGCGCTGCCTCTCGTGTGGCCGCAGCCAGGTGGCGTAGAGGCCCGCATTTGGATTTGG
CTTGGACCTTTCTCTATCCAACCTGGTGAGTTCTCCAAGATTTTGCTGTTGCTGTTCTTTGCTCAGCTGCTAGCCACCAA
GCGTGCGTTGTTTACTGTTGCGGGCTACCGTTTCCTCGGCATGGATTTCCCTCGTTTGCGTGACCTCGCGCCGATTCTTG
TGGTGTGGGCGTTAGCTATTTTGATCATGGCTGGCGCAAACGACTTCGGTCCTGCACTGCTGCTCTTCACCACTGTTTTG
GCCATGGTGTACCTGGCTACCGGCCGTGGTTCCTGGCTTTTGATCGGTGCTGTGTTGGTGGCTGTCGGCGCGTTCGCGGT
GTACCAAGTTTCTGGAAAAATTCAGGAACGCGTACAGAACTTCGTGGATCCTGTGGCCCACTATGACACCACCGGTTACC
AGCTGTCCCAGTCCCTATTCGGCATGAGTTGGGGCGGAATCACCGGCACTGGCATTGGTCAGGGCTACCCCAACATGATC
CCTGTTGTGCACTCCGACTTCATCCTGGCAGCCATTGGTGAGGAGCTGGGTCTGATCGGTCTGGCAGCCATCATCGTGCT
GTTTGGTGTGTTTGTCACCCGCGGAATGCGCACCGCTACCCTGGCTCGTGACAGTTACGGAAAGCTCGTGGCATCTGGTC
TGTCCATGACCATCATGATCCAGATTTTCGTCGTCGTGGCAGGTATTTCTTCGCTGATGCCCATGACAGGTTTGACCACT
CCGTTCATGTCCCAGGGTGGTTCATCGCTTATGGCTAACTACATTTTGCTGGCCATCATTCTGCGTATTTCTGACAGTGC
CCGCCGACCAGTAATGTCCAAGCAAGCATCGGAGGTAGCTGCGTGA

Upstream 100 bases:

>100_bases
TGCAACGGCTGGCTGCTCAAGCTTTGCCGGTATGCGTGAACTTAGAAGTAACAACCGGTGGCGATAGAAACGAACCGGGA
GTCAATTGTAGGGAGGTCTC

Downstream 100 bases:

>100_bases
ACCGCTCGATCCGAATCACATCCCTCTTCTCTTTGCTTTTGATCTTGGTACTCGTGGCAAACCTCACCTGGATTCAGGCT
TTTAGGGACGATGATCTTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MNTLERLKLRRTEMWLLILATLVVSIMFISLELAMGNELGTHILMLMGGYIGIFIVAHLAMAWVAPFADQIMLPVVAVLN
GIGLVMIYRLDEATGYSTVNSQLMWTVVGVTLMVAVLLLLRDYKSLSRYSYLLGVVGIVLLALPLVWPQPGGVEARIWIW
LGPFSIQPGEFSKILLLLFFAQLLATKRALFTVAGYRFLGMDFPRLRDLAPILVVWALAILIMAGANDFGPALLLFTTVL
AMVYLATGRGSWLLIGAVLVAVGAFAVYQVSGKIQERVQNFVDPVAHYDTTGYQLSQSLFGMSWGGITGTGIGQGYPNMI
PVVHSDFILAAIGEELGLIGLAAIIVLFGVFVTRGMRTATLARDSYGKLVASGLSMTIMIQIFVVVAGISSLMPMTGLTT
PFMSQGGSSLMANYILLAIILRISDSARRPVMSKQASEVAA

Sequences:

>Translated_441_residues
MNTLERLKLRRTEMWLLILATLVVSIMFISLELAMGNELGTHILMLMGGYIGIFIVAHLAMAWVAPFADQIMLPVVAVLN
GIGLVMIYRLDEATGYSTVNSQLMWTVVGVTLMVAVLLLLRDYKSLSRYSYLLGVVGIVLLALPLVWPQPGGVEARIWIW
LGPFSIQPGEFSKILLLLFFAQLLATKRALFTVAGYRFLGMDFPRLRDLAPILVVWALAILIMAGANDFGPALLLFTTVL
AMVYLATGRGSWLLIGAVLVAVGAFAVYQVSGKIQERVQNFVDPVAHYDTTGYQLSQSLFGMSWGGITGTGIGQGYPNMI
PVVHSDFILAAIGEELGLIGLAAIIVLFGVFVTRGMRTATLARDSYGKLVASGLSMTIMIQIFVVVAGISSLMPMTGLTT
PFMSQGGSSLMANYILLAIILRISDSARRPVMSKQASEVAA
>Mature_441_residues
MNTLERLKLRRTEMWLLILATLVVSIMFISLELAMGNELGTHILMLMGGYIGIFIVAHLAMAWVAPFADQIMLPVVAVLN
GIGLVMIYRLDEATGYSTVNSQLMWTVVGVTLMVAVLLLLRDYKSLSRYSYLLGVVGIVLLALPLVWPQPGGVEARIWIW
LGPFSIQPGEFSKILLLLFFAQLLATKRALFTVAGYRFLGMDFPRLRDLAPILVVWALAILIMAGANDFGPALLLFTTVL
AMVYLATGRGSWLLIGAVLVAVGAFAVYQVSGKIQERVQNFVDPVAHYDTTGYQLSQSLFGMSWGGITGTGIGQGYPNMI
PVVHSDFILAAIGEELGLIGLAAIIVLFGVFVTRGMRTATLARDSYGKLVASGLSMTIMIQIFVVVAGISSLMPMTGLTT
PFMSQGGSSLMANYILLAIILRISDSARRPVMSKQASEVAA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=375, Percent_Identity=29.3333333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786853, Length=290, Percent_Identity=28.9655172413793, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47750; Mature: 47750

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLERLKLRRTEMWLLILATLVVSIMFISLELAMGNELGTHILMLMGGYIGIFIVAHLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MAWVAPFADQIMLPVVAVLNGIGLVMIYRLDEATGYSTVNSQLMWTVVGVTLMVAVLLLL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RDYKSLSRYSYLLGVVGIVLLALPLVWPQPGGVEARIWIWLGPFSIQPGEFSKILLLLFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHH
AQLLATKRALFTVAGYRFLGMDFPRLRDLAPILVVWALAILIMAGANDFGPALLLFTTVL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AMVYLATGRGSWLLIGAVLVAVGAFAVYQVSGKIQERVQNFVDPVAHYDTTGYQLSQSLF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GMSWGGITGTGIGQGYPNMIPVVHSDFILAAIGEELGLIGLAAIIVLFGVFVTRGMRTAT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LARDSYGKLVASGLSMTIMIQIFVVVAGISSLMPMTGLTTPFMSQGGSSLMANYILLAII
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHH
LRISDSARRPVMSKQASEVAA
HHHCCHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MNTLERLKLRRTEMWLLILATLVVSIMFISLELAMGNELGTHILMLMGGYIGIFIVAHLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MAWVAPFADQIMLPVVAVLNGIGLVMIYRLDEATGYSTVNSQLMWTVVGVTLMVAVLLLL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RDYKSLSRYSYLLGVVGIVLLALPLVWPQPGGVEARIWIWLGPFSIQPGEFSKILLLLFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHH
AQLLATKRALFTVAGYRFLGMDFPRLRDLAPILVVWALAILIMAGANDFGPALLLFTTVL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AMVYLATGRGSWLLIGAVLVAVGAFAVYQVSGKIQERVQNFVDPVAHYDTTGYQLSQSLF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GMSWGGITGTGIGQGYPNMIPVVHSDFILAAIGEELGLIGLAAIIVLFGVFVTRGMRTAT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LARDSYGKLVASGLSMTIMIQIFVVVAGISSLMPMTGLTTPFMSQGGSSLMANYILLAII
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHH
LRISDSARRPVMSKQASEVAA
HHHCCHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]