Click here to switch to the map view.

The map label for this gene is gluP [H]

Identifier: 145294091

GI number: 145294091

Start: 55426

End: 56115

Strand: Direct

Name: gluP [H]

Synonym: cgR_0049

Alternate gene names: 145294091

Gene position: 55426-56115 (Clockwise)

Preceding gene: 145294090

Following gene: 145294093

Centisome position: 1.67

GC content: 49.13

Gene sequence:

>690_bases
TTGAAAGACGAGTTGAAGATTGTTGGATTCATGAATGTAGAACGGATTTATCGACAAGCGCCAGCAAGTACGTTGATCTC
TTTAGCCATCATCGCTGTGTACGCAGTGACGGCCATTCAATCGAGATCAGTGACAGACAACCTGGGTTCAACCAGTATCG
GTGACGCGTGGATTCTGTACGCACCGCTGATGGATGATGGTGGCTTTGGTCCACTGCGTGCCATCGGAGGAATTTTCCTG
CACATTGGCCCCGGGCACATGCTGTTGAACCTTGTGTTGTTGTGGTTGCTGGGAAGAGAAATTGAACGAGACTTCGGTTC
TGCGCTTTTCACTGCGATGTACTTTGTGGGCGGTATTGGTGCGTCTGCAGCTGTCATCTGGATGGATCCCTATTCACCGA
CAGCAGGTGCTTCCGGCGCTATTTACGCCATGATGGCTATTTTGGTGGGGCTTTTTGTGTTAAGAAGCGCGGATATCCGA
GCACCCTTGATCCTTATCGCCATCAACATCGCCTATACCTTGATGTCCACCAATGTTTCTCTGTGGGGACACCTTGGAGG
TTTGATCACTGGAGCTTTAATTACTTGGCCAATGGTTAAAGCGAAAAATAAAAGAACACGGTGGATTATCGTGCTCATTG
GTCTTGCTGTAGTTGTGGTTGCTGTCATCCTAGGAATCGACCGGGTGTAG

Upstream 100 bases:

>100_bases
TCTGTAGAGATCACCGCGTAACAGCCACCTCTACGTACACTAATCTTCAGGTTATGCCGCAAGCCGGTATGACCTGATTT
TTTTATGCCACAAAAACCTG

Downstream 100 bases:

>100_bases
ACACATTCCGCCCATTGCCCTCACCGGGGTCAAAAATCTGACATCCGGTGAGGGTATTTCTGTATCTATCACTTGACAGG
AATTGAACTAAATTACAATT

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKDELKIVGFMNVERIYRQAPASTLISLAIIAVYAVTAIQSRSVTDNLGSTSIGDAWILYAPLMDDGGFGPLRAIGGIFL
HIGPGHMLLNLVLLWLLGREIERDFGSALFTAMYFVGGIGASAAVIWMDPYSPTAGASGAIYAMMAILVGLFVLRSADIR
APLILIAINIAYTLMSTNVSLWGHLGGLITGALITWPMVKAKNKRTRWIIVLIGLAVVVVAVILGIDRV

Sequences:

>Translated_229_residues
MKDELKIVGFMNVERIYRQAPASTLISLAIIAVYAVTAIQSRSVTDNLGSTSIGDAWILYAPLMDDGGFGPLRAIGGIFL
HIGPGHMLLNLVLLWLLGREIERDFGSALFTAMYFVGGIGASAAVIWMDPYSPTAGASGAIYAMMAILVGLFVLRSADIR
APLILIAINIAYTLMSTNVSLWGHLGGLITGALITWPMVKAKNKRTRWIIVLIGLAVVVVAVILGIDRV
>Mature_229_residues
MKDELKIVGFMNVERIYRQAPASTLISLAIIAVYAVTAIQSRSVTDNLGSTSIGDAWILYAPLMDDGGFGPLRAIGGIFL
HIGPGHMLLNLVLLWLLGREIERDFGSALFTAMYFVGGIGASAAVIWMDPYSPTAGASGAIYAMMAILVGLFVLRSADIR
APLILIAINIAYTLMSTNVSLWGHLGGLITGALITWPMVKAKNKRTRWIIVLIGLAVVVVAVILGIDRV

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 24527; Mature: 24527

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDELKIVGFMNVERIYRQAPASTLISLAIIAVYAVTAIQSRSVTDNLGSTSIGDAWILY
CCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
APLMDDGGFGPLRAIGGIFLHIGPGHMLLNLVLLWLLGREIERDFGSALFTAMYFVGGIG
EEECCCCCCCHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASAAVIWMDPYSPTAGASGAIYAMMAILVGLFVLRSADIRAPLILIAINIAYTLMSTNVS
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHH
LWGHLGGLITGALITWPMVKAKNKRTRWIIVLIGLAVVVVAVILGIDRV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKDELKIVGFMNVERIYRQAPASTLISLAIIAVYAVTAIQSRSVTDNLGSTSIGDAWILY
CCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
APLMDDGGFGPLRAIGGIFLHIGPGHMLLNLVLLWLLGREIERDFGSALFTAMYFVGGIG
EEECCCCCCCHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASAAVIWMDPYSPTAGASGAIYAMMAILVGLFVLRSADIRAPLILIAINIAYTLMSTNVS
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHH
LWGHLGGLITGALITWPMVKAKNKRTRWIIVLIGLAVVVVAVILGIDRV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]