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The map label for this gene is feaR [H]

Identifier: 145294059

GI number: 145294059

Start: 17786

End: 18712

Strand: Reverse

Name: feaR [H]

Synonym: cgR_0017

Alternate gene names: 145294059

Gene position: 18712-17786 (Counterclockwise)

Preceding gene: 145294061

Following gene: 145294054

Centisome position: 0.56

GC content: 51.35

Gene sequence:

>927_bases
ATGGAGTCAATCCAGGCATACAATTTCACTCAATGGCGACAAATTGTCGCTTCAAGTTTTCACAACGTGCGTGCTGCAGC
CCCAGCACCAAATTTCCGCGCGACAGCTCACCACAAACACGTTGGGGACATTGAACTCTTCGACATGATCACTGATCCCC
ACACGGTGATCCATACAGAAGGCGACGGCTCTTTCCCGCTAAGCACCATGTGCAAGTTTAGCCTGCAGTTAGAGGGAGTA
GCCACGCTCGTTCAAGATGGTCGTTCCTGCACAATGTCCCCAGGCGATCTTGCTCTTTATACAGGTAAACGCCCGTATCA
CCTTGTATTCGATGAACCACAACGCAGCCTGGTTGTGTATTTTCCGAGGAGTCTCCTCCAGCTTCGCGACGATCAAATCG
ACATGATCACCGCTACCCCGATTTCCAGGGATGAGGGGCTGGGGAAAATCATCATTCCTCTTTTCGAACAATTTGCTCGA
AACCTTGATGATCTACAGGGACTTCATGCACAATCGCTGATCCGCGCATCACTTGATCTTCTAGTTACCGTATTTGCTGA
ACACACTGAGCGAATGAACGGAGAATTAGAGGATTCATCTCAGCTGTTTCGACGGGCGACCAGCTACATCGATGAAAACC
TGCACGATCTTGACCTTGCCCCTGGAACTATTGCTGATGCTTTGTATGTTTCAGTCCGTAACCTCCACGCCCATTTCTCC
AGTCAGGGACTGACTGTGTCAGCGTATATTCGGGCGAGACGTCTGAATGCAATCCACGCAGACCTGGGCAATCCTCAGAT
GCGCGACTTCACCATCCAGAGCATCAGCGCCCGACACGGACTTGTTGATGCCTCCTATGTTTCCAAAGCTTTCCGAGCCG
AATACGGTGAGTCGCCGCGCACCTACCGTACGCGGACCCTCACTTAA

Upstream 100 bases:

>100_bases
ACAGCGCACCATAGTTGTTCCCCAGTGTGAGGCGCATCTCATAACATGAGAAGCCTTACCCTAGTCATCACAATTGACGT
GTTTTGATATGGAGCCAATC

Downstream 100 bases:

>100_bases
ATCGACTACAAAATTTCTTTCGCCACATCACGTGCGGTGCGAATACCCATTTCCAATGCACCATCAATGACCACACCACG
CCATCCCCGAGCCCAATCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MESIQAYNFTQWRQIVASSFHNVRAAAPAPNFRATAHHKHVGDIELFDMITDPHTVIHTEGDGSFPLSTMCKFSLQLEGV
ATLVQDGRSCTMSPGDLALYTGKRPYHLVFDEPQRSLVVYFPRSLLQLRDDQIDMITATPISRDEGLGKIIIPLFEQFAR
NLDDLQGLHAQSLIRASLDLLVTVFAEHTERMNGELEDSSQLFRRATSYIDENLHDLDLAPGTIADALYVSVRNLHAHFS
SQGLTVSAYIRARRLNAIHADLGNPQMRDFTIQSISARHGLVDASYVSKAFRAEYGESPRTYRTRTLT

Sequences:

>Translated_308_residues
MESIQAYNFTQWRQIVASSFHNVRAAAPAPNFRATAHHKHVGDIELFDMITDPHTVIHTEGDGSFPLSTMCKFSLQLEGV
ATLVQDGRSCTMSPGDLALYTGKRPYHLVFDEPQRSLVVYFPRSLLQLRDDQIDMITATPISRDEGLGKIIIPLFEQFAR
NLDDLQGLHAQSLIRASLDLLVTVFAEHTERMNGELEDSSQLFRRATSYIDENLHDLDLAPGTIADALYVSVRNLHAHFS
SQGLTVSAYIRARRLNAIHADLGNPQMRDFTIQSISARHGLVDASYVSKAFRAEYGESPRTYRTRTLT
>Mature_308_residues
MESIQAYNFTQWRQIVASSFHNVRAAAPAPNFRATAHHKHVGDIELFDMITDPHTVIHTEGDGSFPLSTMCKFSLQLEGV
ATLVQDGRSCTMSPGDLALYTGKRPYHLVFDEPQRSLVVYFPRSLLQLRDDQIDMITATPISRDEGLGKIIIPLFEQFAR
NLDDLQGLHAQSLIRASLDLLVTVFAEHTERMNGELEDSSQLFRRATSYIDENLHDLDLAPGTIADALYVSVRNLHAHFS
SQGLTVSAYIRARRLNAIHADLGNPQMRDFTIQSISARHGLVDASYVSKAFRAEYGESPRTYRTRTLT

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=231, Percent_Identity=28.1385281385281, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34589; Mature: 34589

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIQAYNFTQWRQIVASSFHNVRAAAPAPNFRATAHHKHVGDIELFDMITDPHTVIHTE
CCCCCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEC
GDGSFPLSTMCKFSLQLEGVATLVQDGRSCTMSPGDLALYTGKRPYHLVFDEPQRSLVVY
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCCCEEEE
FPRSLLQLRDDQIDMITATPISRDEGLGKIIIPLFEQFARNLDDLQGLHAQSLIRASLDL
ECHHHHHHCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHCHHHHHCHHHHHHHHHHHHH
LVTVFAEHTERMNGELEDSSQLFRRATSYIDENLHDLDLAPGTIADALYVSVRNLHAHFS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
SQGLTVSAYIRARRLNAIHADLGNPQMRDFTIQSISARHGLVDASYVSKAFRAEYGESPR
CCCCEEEEEHHHHHHHHHECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
TYRTRTLT
CCEEECCC
>Mature Secondary Structure
MESIQAYNFTQWRQIVASSFHNVRAAAPAPNFRATAHHKHVGDIELFDMITDPHTVIHTE
CCCCCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEC
GDGSFPLSTMCKFSLQLEGVATLVQDGRSCTMSPGDLALYTGKRPYHLVFDEPQRSLVVY
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCCCEEEE
FPRSLLQLRDDQIDMITATPISRDEGLGKIIIPLFEQFARNLDDLQGLHAQSLIRASLDL
ECHHHHHHCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHCHHHHHCHHHHHHHHHHHHH
LVTVFAEHTERMNGELEDSSQLFRRATSYIDENLHDLDLAPGTIADALYVSVRNLHAHFS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
SQGLTVSAYIRARRLNAIHADLGNPQMRDFTIQSISARHGLVDASYVSKAFRAEYGESPR
CCCCEEEEEHHHHHHHHHECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
TYRTRTLT
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]