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The map label for this gene is cycA [C]

Identifier: 145294057

GI number: 145294057

Start: 15244

End: 16440

Strand: Direct

Name: cycA [C]

Synonym: cgR_0015

Alternate gene names: 145294057

Gene position: 15244-16440 (Clockwise)

Preceding gene: 145294056

Following gene: 145294058

Centisome position: 0.46

GC content: 50.21

Gene sequence:

>1197_bases
ATGTACGGACTCTTCGGATTCTCCCTCTCTGCCGCAATCGCAGCATGGACAGGGGTGGCGATACCCTGGTGGATCGTCGG
CCTCGTTGGCTGGGTTTTCGTTGCATTGATGGGTGTGAGCAATGTTGAATTATCAGCGAAAGTCTTAGGAGTGCTGGTCG
CTCTTGAGTTCCTCGTTGCGATTGTTGTCATGATTGTGGCTCTCATACATTCACCTGAGGGAATCAGTACAGCGACACTT
CATGCAGAAGACTTCTTTGTTCCGGGAATAGGTGTTTTACTAGCTTTTTCCATCGCCGCTTTTATGGGCTTTGAATCGGG
GGCTATCTACTCAGAAGAAACTAAAGACCCGAGCAAAACAGTTTCCCGGGCAACCTACATTGCGGTCGGCATTATTGCGA
TATTTTATGCGGCTTCGACGTGGGCGCTCGCGATGGGAGTGGGACCTTCTGCAATCATCGATGAGTCCCGCATTTATGGC
CCCGACCTGGTATTTGTGTGGCTTGCTAGCTTTTCACCTGCACTCTCCAACGTTGCACATCTACTTTTTGTGACGAGTAT
TCTCGCCGCGCTACTCGCATTCCATAACGCAGCTGCACGTTATTTCTTTGCACTTGGACGTTCAAAAGTAATTCCAAGTG
TGTTTGGCAAACTCGGTAAAAATGGAGCCCCAATCGGAGGCTCGATCGCCCAATCAGTTGTTGGTCTGGTGGTCGTGATT
GTTTTTGCAATCGGCGGAGCAAACTCAACGCTCGGGGAGCTATTTCCTGTGACGACCTTATTCACCTGGTTTTCCACGGC
AGCGGCATTCGGGTTGGTGTTCCTCATGGCGATTACTTCGGTGGCTGTACTTTTCTGGTTCCGCCGAAACCACCATGGAT
ATGGAGTATTTACCAGGGTGATCGCGCCGGGAGCAGCTGCACTTTTCCTAGTCGTTATTGCAGTGCTCATCCTGATGAAC
TTCGACATCATGATCGGCGAAGAATCACCACGAGCCATGATTTTCATCATGCCAGGCATCATCATCGGAACTGGTGTGCT
GGGTGCACTGTGGTCATTGCGTTTCGACAGAGAAATCGACGTCAACGCAATTCCAATCGCAGAAACAGCGGTGGTTGATG
AATCAGGAACTGGTTCAAACGCTGGTTCAAACGCTGAAGATACACAAGCAAGTTCACCTGCCCACACAACCATTTAG

Upstream 100 bases:

>100_bases
TGGCGCTTTCTACGCTTATATTTCTCAAGGGTTAGGTCCTCGGCAAGGTATTGCCGCAGCTCTCCTAGCTTTAGTTTCAT
ACAATCTCCTCCAAGCAGGA

Downstream 100 bases:

>100_bases
AAACACCTTTGAGAAAGAGGAACGAAATGACCAAGAAAGTTGTAGTTGTTGGAGCTGGGTTTGCGGGTCTGGTTGCAGCT
CGAGAGCTTCAAATGTTTGG

Product: hypothetical protein

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: Amino Acid Permease; Amino Acid Transporter; Amino Acid Permease-Associated Protein; Permease; Transmembrane Permease Protein; Amino Acid Permease Family Protein; Amino-Acid Transporter Transmembrane Protein; Amino Acid Permease Purative; Phenylethylamine Permease; Amino-Acid Permease

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MYGLFGFSLSAAIAAWTGVAIPWWIVGLVGWVFVALMGVSNVELSAKVLGVLVALEFLVAIVVMIVALIHSPEGISTATL
HAEDFFVPGIGVLLAFSIAAFMGFESGAIYSEETKDPSKTVSRATYIAVGIIAIFYAASTWALAMGVGPSAIIDESRIYG
PDLVFVWLASFSPALSNVAHLLFVTSILAALLAFHNAAARYFFALGRSKVIPSVFGKLGKNGAPIGGSIAQSVVGLVVVI
VFAIGGANSTLGELFPVTTLFTWFSTAAAFGLVFLMAITSVAVLFWFRRNHHGYGVFTRVIAPGAAALFLVVIAVLILMN
FDIMIGEESPRAMIFIMPGIIIGTGVLGALWSLRFDREIDVNAIPIAETAVVDESGTGSNAGSNAEDTQASSPAHTTI

Sequences:

>Translated_398_residues
MYGLFGFSLSAAIAAWTGVAIPWWIVGLVGWVFVALMGVSNVELSAKVLGVLVALEFLVAIVVMIVALIHSPEGISTATL
HAEDFFVPGIGVLLAFSIAAFMGFESGAIYSEETKDPSKTVSRATYIAVGIIAIFYAASTWALAMGVGPSAIIDESRIYG
PDLVFVWLASFSPALSNVAHLLFVTSILAALLAFHNAAARYFFALGRSKVIPSVFGKLGKNGAPIGGSIAQSVVGLVVVI
VFAIGGANSTLGELFPVTTLFTWFSTAAAFGLVFLMAITSVAVLFWFRRNHHGYGVFTRVIAPGAAALFLVVIAVLILMN
FDIMIGEESPRAMIFIMPGIIIGTGVLGALWSLRFDREIDVNAIPIAETAVVDESGTGSNAGSNAEDTQASSPAHTTI
>Mature_398_residues
MYGLFGFSLSAAIAAWTGVAIPWWIVGLVGWVFVALMGVSNVELSAKVLGVLVALEFLVAIVVMIVALIHSPEGISTATL
HAEDFFVPGIGVLLAFSIAAFMGFESGAIYSEETKDPSKTVSRATYIAVGIIAIFYAASTWALAMGVGPSAIIDESRIYG
PDLVFVWLASFSPALSNVAHLLFVTSILAALLAFHNAAARYFFALGRSKVIPSVFGKLGKNGAPIGGSIAQSVVGLVVVI
VFAIGGANSTLGELFPVTTLFTWFSTAAAFGLVFLMAITSVAVLFWFRRNHHGYGVFTRVIAPGAAALFLVVIAVLILMN
FDIMIGEESPRAMIFIMPGIIIGTGVLGALWSLRFDREIDVNAIPIAETAVVDESGTGSNAGSNAEDTQASSPAHTTI

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of D-Alanine, D-Serine And Glycine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41772; Mature: 41772

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGLFGFSLSAAIAAWTGVAIPWWIVGLVGWVFVALMGVSNVELSAKVLGVLVALEFLVA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IVVMIVALIHSPEGISTATLHAEDFFVPGIGVLLAFSIAAFMGFESGAIYSEETKDPSKT
HHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VSRATYIAVGIIAIFYAASTWALAMGVGPSAIIDESRIYGPDLVFVWLASFSPALSNVAH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHH
LLFVTSILAALLAFHNAAARYFFALGRSKVIPSVFGKLGKNGAPIGGSIAQSVVGLVVVI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VFAIGGANSTLGELFPVTTLFTWFSTAAAFGLVFLMAITSVAVLFWFRRNHHGYGVFTRV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IAPGAAALFLVVIAVLILMNFDIMIGEESPRAMIFIMPGIIIGTGVLGALWSLRFDREID
HCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCC
VNAIPIAETAVVDESGTGSNAGSNAEDTQASSPAHTTI
CCEECCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYGLFGFSLSAAIAAWTGVAIPWWIVGLVGWVFVALMGVSNVELSAKVLGVLVALEFLVA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IVVMIVALIHSPEGISTATLHAEDFFVPGIGVLLAFSIAAFMGFESGAIYSEETKDPSKT
HHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VSRATYIAVGIIAIFYAASTWALAMGVGPSAIIDESRIYGPDLVFVWLASFSPALSNVAH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHH
LLFVTSILAALLAFHNAAARYFFALGRSKVIPSVFGKLGKNGAPIGGSIAQSVVGLVVVI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VFAIGGANSTLGELFPVTTLFTWFSTAAAFGLVFLMAITSVAVLFWFRRNHHGYGVFTRV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IAPGAAALFLVVIAVLILMNFDIMIGEESPRAMIFIMPGIIIGTGVLGALWSLRFDREID
HCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCC
VNAIPIAETAVVDESGTGSNAGSNAEDTQASSPAHTTI
CCEECCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA