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The map label for this gene is pbpG [H]

Identifier: 138896980

GI number: 138896980

Start: 3459493

End: 3461538

Strand: Direct

Name: pbpG [H]

Synonym: GTNG_3351

Alternate gene names: 138896980

Gene position: 3459493-3461538 (Clockwise)

Preceding gene: 138896973

Following gene: 138896983

Centisome position: 97.44

GC content: 52.39

Gene sequence:

>2046_bases
ATGGAACCGATCCCGGGCAGTCGTTTTCGCGGCACGTGGAAATATGTGCGCGCCGCCGTCTTTATTGGCTGTTTTCTCAC
AATCTTTGCTTTCGCTGCCCTCGGGAGTTTTATTTTGTTTGCGAAAATCGGAGGCGCCCCACCGGTCGCTGTGCCGCAAA
CGACGGTTTTTTATGCAGATGATGGCAGCAAAATCGGGGAAAGCAATTATGGACAGAAGCGCTACTGGGTTCGTCTTGAT
GACATTTCCCCGCACGTCATTGAAGCGACGATCGCCGTCGAAGACCGAAAGTTTTACGAACACCATGGATTTGATTTGAA
ACGAATTGCCGGCGCCGTCGTCGCCAATGTGCAGGCGATGGCCAAAGTCGAAGGAGCAAGCACGATCACCCAGCAATATG
CGCGCAACTTATTTTTGACGCACGAGAAAACATGGTCGCGAAAAATTCAAGAGGCGCTCTATACCATCCGACTTGAAGCC
AACTACAGCAAAGAACAAATTTTGGAAGGCTATTTAAACACGATTTACTATGGACATGGGGTTTACGGTATCGAGGCAGC
GGCGCGCTATTATTTCGGCAAGCACGCCGATGAGCTGACGATCAGCGAAGCAGCGATGCTAGCCGGCATCCCAAAAGGAC
CGCACTATTATTCGCCGCTCATCAACGAAGAGCGGGCGAAAACGCGGCAAAAAATCGTCCTCCTCTCGATGGTGGAAGCG
GGCTACATCAGCCGCCAGGAGGCGGAACAGGCGTACCGCGACAAGCTCGTCTACGTGCAGCACCGCGAGAAAGAGCGGCC
TATCGCTCCATATTTTCAAGACGTCGTCAAACAGCAGTTGCGCACGAAACTCGGCCTTGACGAGCGCACGATCGAGCTCG
GCGGACTGCGCGTCTACACGACGCTCGACCGGCGCATGCAGCAAATCGCCGAAGAGCAACTTGAACAGGTGATCCGTCCC
TCTTCCGCCATCCAAGCAGCGTTATTGGCCATGGATCCACGCACCGGGGAAGTAAAAGCGCTCATCGGTGGGCGCGACTA
CAACGAGAGCCCATTCAATCGCGCCGTACAGGCGGAACGCCAGCCAGGCTCGACGTTCAAACCATTTTTGTACTACGCGG
CCATCGAACATGGATTCACCCCGTCGACCCCATTGCGCAGCGAACTGACGACGTTTACGTTTGACGACGGCCGGGCGACG
TATACGCCTCATAACTACAATGATTACTACGCAAACGGCCCGATTACGCTCGCCCAAGCGCTTGCCGTATCGGACAACGT
CTTTGCGGTAAAAACACTGAAGTTTATCGGCGCCGACAAACTGATCGAAACGGCGAAAACGCTCGGCATTACAAGCAAAT
TAAAAGCCGTGCCATCGCTAGCCCTCGGCACATCGCCAGTGAAAATGATCGATATGGTCGCGGCGTACAGCACGATCGCC
AACTACGGCAAAAAAACGGAGCCGGTGTTTATTAAAAAAGTCATCGATGCGAACGGAAACGTGTTATACGAGCATCAGCC
GTCAACCCAACAAGTGATCGACCGCGATGCCGCGTTTGTGACGGCGCATTTAATGACCGGGATGTTCGACCCGAAGCTGA
ACGGCTATACGACCGTCACTGGACAATCAATCATCGATGAAATAACGCGTCCTTATGCCGGAAAATCCGGAACGACGAAA
ACGGACAGCTGGATGATTGGCTTTACCCCGCAGTTGGTTGCTGGCGTCTGGACCGGTTACGACCGTGGGGAAACGATCAG
CCGTTTTGATGAAAAACAGTATGCGAAGCAAATATGGGTCCGCTTTATGGAACAAAGTCTCGCTGACAAGCCGAAAAAAT
CGTTTAAACCGACAAAAGGTGTCATCGGCGTCTACATCGATCCGCAAAACGGAAAGCTGGCCACCGATGCTTGTCCGGTG
AAACGAAAAACGTATTATCTCATTGGCACAGAACCGACCGACTATTGCACGGATCATTTGGAGAAGAAAACAAAGAAAAA
AGAGGACGAAAAAAGCTGGTTTGAGAAATGGTTCCCATGGTTTTAA

Upstream 100 bases:

>100_bases
AGAAATCGCCTGACTGAGATATGGGGACGGAGGCAACATAAGGCGATTTTGGGGCAGTCATCCGTCCTAATTACCGCTAA
AACCATTGGGGGGATGCGCA

Downstream 100 bases:

>100_bases
AGAAAATCCCCCGCACATATGTGCGGGGGATTTTCTTGTCCTAGTTTTCCTGTGTTATACATGTAGGTTTAGTTTATCCC
TTTTTCTAGGCAATAACAAG

Product: penicillin-binding protein-like protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MEPIPGSRFRGTWKYVRAAVFIGCFLTIFAFAALGSFILFAKIGGAPPVAVPQTTVFYADDGSKIGESNYGQKRYWVRLD
DISPHVIEATIAVEDRKFYEHHGFDLKRIAGAVVANVQAMAKVEGASTITQQYARNLFLTHEKTWSRKIQEALYTIRLEA
NYSKEQILEGYLNTIYYGHGVYGIEAAARYYFGKHADELTISEAAMLAGIPKGPHYYSPLINEERAKTRQKIVLLSMVEA
GYISRQEAEQAYRDKLVYVQHREKERPIAPYFQDVVKQQLRTKLGLDERTIELGGLRVYTTLDRRMQQIAEEQLEQVIRP
SSAIQAALLAMDPRTGEVKALIGGRDYNESPFNRAVQAERQPGSTFKPFLYYAAIEHGFTPSTPLRSELTTFTFDDGRAT
YTPHNYNDYYANGPITLAQALAVSDNVFAVKTLKFIGADKLIETAKTLGITSKLKAVPSLALGTSPVKMIDMVAAYSTIA
NYGKKTEPVFIKKVIDANGNVLYEHQPSTQQVIDRDAAFVTAHLMTGMFDPKLNGYTTVTGQSIIDEITRPYAGKSGTTK
TDSWMIGFTPQLVAGVWTGYDRGETISRFDEKQYAKQIWVRFMEQSLADKPKKSFKPTKGVIGVYIDPQNGKLATDACPV
KRKTYYLIGTEPTDYCTDHLEKKTKKKEDEKSWFEKWFPWF

Sequences:

>Translated_681_residues
MEPIPGSRFRGTWKYVRAAVFIGCFLTIFAFAALGSFILFAKIGGAPPVAVPQTTVFYADDGSKIGESNYGQKRYWVRLD
DISPHVIEATIAVEDRKFYEHHGFDLKRIAGAVVANVQAMAKVEGASTITQQYARNLFLTHEKTWSRKIQEALYTIRLEA
NYSKEQILEGYLNTIYYGHGVYGIEAAARYYFGKHADELTISEAAMLAGIPKGPHYYSPLINEERAKTRQKIVLLSMVEA
GYISRQEAEQAYRDKLVYVQHREKERPIAPYFQDVVKQQLRTKLGLDERTIELGGLRVYTTLDRRMQQIAEEQLEQVIRP
SSAIQAALLAMDPRTGEVKALIGGRDYNESPFNRAVQAERQPGSTFKPFLYYAAIEHGFTPSTPLRSELTTFTFDDGRAT
YTPHNYNDYYANGPITLAQALAVSDNVFAVKTLKFIGADKLIETAKTLGITSKLKAVPSLALGTSPVKMIDMVAAYSTIA
NYGKKTEPVFIKKVIDANGNVLYEHQPSTQQVIDRDAAFVTAHLMTGMFDPKLNGYTTVTGQSIIDEITRPYAGKSGTTK
TDSWMIGFTPQLVAGVWTGYDRGETISRFDEKQYAKQIWVRFMEQSLADKPKKSFKPTKGVIGVYIDPQNGKLATDACPV
KRKTYYLIGTEPTDYCTDHLEKKTKKKEDEKSWFEKWFPWF
>Mature_681_residues
MEPIPGSRFRGTWKYVRAAVFIGCFLTIFAFAALGSFILFAKIGGAPPVAVPQTTVFYADDGSKIGESNYGQKRYWVRLD
DISPHVIEATIAVEDRKFYEHHGFDLKRIAGAVVANVQAMAKVEGASTITQQYARNLFLTHEKTWSRKIQEALYTIRLEA
NYSKEQILEGYLNTIYYGHGVYGIEAAARYYFGKHADELTISEAAMLAGIPKGPHYYSPLINEERAKTRQKIVLLSMVEA
GYISRQEAEQAYRDKLVYVQHREKERPIAPYFQDVVKQQLRTKLGLDERTIELGGLRVYTTLDRRMQQIAEEQLEQVIRP
SSAIQAALLAMDPRTGEVKALIGGRDYNESPFNRAVQAERQPGSTFKPFLYYAAIEHGFTPSTPLRSELTTFTFDDGRAT
YTPHNYNDYYANGPITLAQALAVSDNVFAVKTLKFIGADKLIETAKTLGITSKLKAVPSLALGTSPVKMIDMVAAYSTIA
NYGKKTEPVFIKKVIDANGNVLYEHQPSTQQVIDRDAAFVTAHLMTGMFDPKLNGYTTVTGQSIIDEITRPYAGKSGTTK
TDSWMIGFTPQLVAGVWTGYDRGETISRFDEKQYAKQIWVRFMEQSLADKPKKSFKPTKGVIGVYIDPQNGKLATDACPV
KRKTYYLIGTEPTDYCTDHLEKKTKKKEDEKSWFEKWFPWF

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=539, Percent_Identity=31.9109461966605, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1788867, Length=661, Percent_Identity=28.7443267776097, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI87082258, Length=263, Percent_Identity=41.4448669201521, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789601, Length=177, Percent_Identity=42.9378531073446, Blast_Score=133, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 76750; Mature: 76750

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIPGSRFRGTWKYVRAAVFIGCFLTIFAFAALGSFILFAKIGGAPPVAVPQTTVFYAD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
DGSKIGESNYGQKRYWVRLDDISPHVIEATIAVEDRKFYEHHGFDLKRIAGAVVANVQAM
CCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHH
AKVEGASTITQQYARNLFLTHEKTWSRKIQEALYTIRLEANYSKEQILEGYLNTIYYGHG
HHHCCHHHHHHHHHHHEEEECCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHEECCC
VYGIEAAARYYFGKHADELTISEAAMLAGIPKGPHYYSPLINEERAKTRQKIVLLSMVEA
CHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GYISRQEAEQAYRDKLVYVQHREKERPIAPYFQDVVKQQLRTKLGLDERTIELGGLRVYT
CCCCHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECCEEEEH
TLDRRMQQIAEEQLEQVIRPSSAIQAALLAMDPRTGEVKALIGGRDYNESPFNRAVQAER
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHCCC
QPGSTFKPFLYYAAIEHGFTPSTPLRSELTTFTFDDGRATYTPHNYNDYYANGPITLAQA
CCCCCCCHHHHHHHHHCCCCCCCCCHHCCCEEEECCCCEEECCCCCCCEECCCCHHHHHH
LAVSDNVFAVKTLKFIGADKLIETAKTLGITSKLKAVPSLALGTSPVKMIDMVAAYSTIA
HHHCCCEEEEHHHHHHCHHHHHHHHHHHCHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
NYGKKTEPVFIKKVIDANGNVLYEHQPSTQQVIDRDAAFVTAHLMTGMFDPKLNGYTTVT
HCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
GQSIIDEITRPYAGKSGTTKTDSWMIGFTPQLVAGVWTGYDRGETISRFDEKQYAKQIWV
HHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
RFMEQSLADKPKKSFKPTKGVIGVYIDPQNGKLATDACPVKRKTYYLIGTEPTDYCTDHL
HHHHHHHHCCCHHHCCCCCCEEEEEEECCCCEEECCCCCCCCCEEEEEECCCHHHHHHHH
EKKTKKKEDEKSWFEKWFPWF
HHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MEPIPGSRFRGTWKYVRAAVFIGCFLTIFAFAALGSFILFAKIGGAPPVAVPQTTVFYAD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
DGSKIGESNYGQKRYWVRLDDISPHVIEATIAVEDRKFYEHHGFDLKRIAGAVVANVQAM
CCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHH
AKVEGASTITQQYARNLFLTHEKTWSRKIQEALYTIRLEANYSKEQILEGYLNTIYYGHG
HHHCCHHHHHHHHHHHEEEECCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHEECCC
VYGIEAAARYYFGKHADELTISEAAMLAGIPKGPHYYSPLINEERAKTRQKIVLLSMVEA
CHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GYISRQEAEQAYRDKLVYVQHREKERPIAPYFQDVVKQQLRTKLGLDERTIELGGLRVYT
CCCCHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECCEEEEH
TLDRRMQQIAEEQLEQVIRPSSAIQAALLAMDPRTGEVKALIGGRDYNESPFNRAVQAER
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHCCC
QPGSTFKPFLYYAAIEHGFTPSTPLRSELTTFTFDDGRATYTPHNYNDYYANGPITLAQA
CCCCCCCHHHHHHHHHCCCCCCCCCHHCCCEEEECCCCEEECCCCCCCEECCCCHHHHHH
LAVSDNVFAVKTLKFIGADKLIETAKTLGITSKLKAVPSLALGTSPVKMIDMVAAYSTIA
HHHCCCEEEEHHHHHHCHHHHHHHHHHHCHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
NYGKKTEPVFIKKVIDANGNVLYEHQPSTQQVIDRDAAFVTAHLMTGMFDPKLNGYTTVT
HCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
GQSIIDEITRPYAGKSGTTKTDSWMIGFTPQLVAGVWTGYDRGETISRFDEKQYAKQIWV
HHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
RFMEQSLADKPKKSFKPTKGVIGVYIDPQNGKLATDACPVKRKTYYLIGTEPTDYCTDHL
HHHHHHHHCCCHHHCCCCCCEEEEEEECCCCEEECCCCCCCCCEEEEEECCCHHHHHHHH
EKKTKKKEDEKSWFEKWFPWF
HHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]