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The map label for this gene is glvR [H]

Identifier: 138896855

GI number: 138896855

Start: 3327756

End: 3328502

Strand: Direct

Name: glvR [H]

Synonym: GTNG_3218

Alternate gene names: 138896855

Gene position: 3327756-3328502 (Clockwise)

Preceding gene: 138896851

Following gene: 138896864

Centisome position: 93.73

GC content: 41.1

Gene sequence:

>747_bases
ATGGGAAAACTTCTGGATCGATTTTCAAACTATATCGGCCAACTCACCCATGCAGAAAAACACGTTTTGTACTATATCGA
TGGACATGTGGAACAAGCGAAACAATTATCGCTAACTGCTATGGCGGAAAAAAACAACGTCAGCACCACCACCATCATCC
GTATGTGTCATAAACTGGGCTTAGAAGGTTTCTCAGAGTTGAAATATATTCTGAAAACGATCGACGACCAAGCCATTCCG
GTTGGAGAAAATACGATTGAACGGTACAAAGCCGATATGAATCAGACACTTGATTCGTTGGAACGAAAACATGTGGAAGA
AATTAGCCAGTTGATTTTTGAGGCCAATCGAGTGTTGATTGTGGCGGTTGGTCTATCCAAAATGATCGGGGAATATTTTA
GCAAACTTCTCATCCAAGTAAACAAGCCGAGCTCGTATGTGTATGAATCACATATTATTGACCTTTTACCCAACATGGTT
CAACCAAAAGATATGGTCATTTTCATTTCATCCAGCGGAGAGACAAAAACCATTGTGCAAGCGGCAGAGAAACTTCGCTT
TAAAAACATCGAAACGGTAGCGATCACGAACAGCGCCGATAGTACATTAGCCAAACTTGTACGAAAACATATCAGCGCCT
ACGTGCAACGTGTCCAGTTTGCGGGTTATGACCTATCTGCCCGTTCGACCCTCGTTGTTCTGATTGACATTTTATTTGAA
TTTTTCATGAAAAACTATAAAGCATAA

Upstream 100 bases:

>100_bases
CTTCTTTCTCCTCAAAACTGACGGGGGTTTTCCCTCGAACGGCCTATAGCATGTGTTATAATATTGTTAAAATAGCGACG
ATAAGCAAAGGAGTCTCCAT

Downstream 100 bases:

>100_bases
CCAGCGGCATCGAAACTGCCTTTAAGCCACGTTCACTTCATTCGCTGCAACATTTATTAACCGCCTTTCCACCATGAATG
GAGACTCGTAAAGGACGAGA

Product: putative regulator

Products: NA

Alternate protein names: Glv operon regulatory protein [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MGKLLDRFSNYIGQLTHAEKHVLYYIDGHVEQAKQLSLTAMAEKNNVSTTTIIRMCHKLGLEGFSELKYILKTIDDQAIP
VGENTIERYKADMNQTLDSLERKHVEEISQLIFEANRVLIVAVGLSKMIGEYFSKLLIQVNKPSSYVYESHIIDLLPNMV
QPKDMVIFISSSGETKTIVQAAEKLRFKNIETVAITNSADSTLAKLVRKHISAYVQRVQFAGYDLSARSTLVVLIDILFE
FFMKNYKA

Sequences:

>Translated_248_residues
MGKLLDRFSNYIGQLTHAEKHVLYYIDGHVEQAKQLSLTAMAEKNNVSTTTIIRMCHKLGLEGFSELKYILKTIDDQAIP
VGENTIERYKADMNQTLDSLERKHVEEISQLIFEANRVLIVAVGLSKMIGEYFSKLLIQVNKPSSYVYESHIIDLLPNMV
QPKDMVIFISSSGETKTIVQAAEKLRFKNIETVAITNSADSTLAKLVRKHISAYVQRVQFAGYDLSARSTLVVLIDILFE
FFMKNYKA
>Mature_247_residues
GKLLDRFSNYIGQLTHAEKHVLYYIDGHVEQAKQLSLTAMAEKNNVSTTTIIRMCHKLGLEGFSELKYILKTIDDQAIPV
GENTIERYKADMNQTLDSLERKHVEEISQLIFEANRVLIVAVGLSKMIGEYFSKLLIQVNKPSSYVYESHIIDLLPNMVQ
PKDMVIFISSSGETKTIVQAAEKLRFKNIETVAITNSADSTLAKLVRKHISAYVQRVQFAGYDLSARSTLVVLIDILFEF
FMKNYKA

Specific function: Positive regulator of the glv operon expression, which consists of glvA, glvR and glvC [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=256, Percent_Identity=24.21875, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082130, Length=257, Percent_Identity=22.568093385214, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28158; Mature: 28027

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLLDRFSNYIGQLTHAEKHVLYYIDGHVEQAKQLSLTAMAEKNNVSTTTIIRMCHKLG
CCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
LEGFSELKYILKTIDDQAIPVGENTIERYKADMNQTLDSLERKHVEEISQLIFEANRVLI
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VAVGLSKMIGEYFSKLLIQVNKPSSYVYESHIIDLLPNMVQPKDMVIFISSSGETKTIVQ
EEECHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHH
AAEKLRFKNIETVAITNSADSTLAKLVRKHISAYVQRVQFAGYDLSARSTLVVLIDILFE
HHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FFMKNYKA
HHHHHCCC
>Mature Secondary Structure 
GKLLDRFSNYIGQLTHAEKHVLYYIDGHVEQAKQLSLTAMAEKNNVSTTTIIRMCHKLG
CHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
LEGFSELKYILKTIDDQAIPVGENTIERYKADMNQTLDSLERKHVEEISQLIFEANRVLI
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VAVGLSKMIGEYFSKLLIQVNKPSSYVYESHIIDLLPNMVQPKDMVIFISSSGETKTIVQ
EEECHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHH
AAEKLRFKNIETVAITNSADSTLAKLVRKHISAYVQRVQFAGYDLSARSTLVVLIDILFE
HHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FFMKNYKA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]