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The map label for this gene is crp [C]

Identifier: 138896801

GI number: 138896801

Start: 3265804

End: 3266466

Strand: Direct

Name: crp [C]

Synonym: GTNG_3164

Alternate gene names: 138896801

Gene position: 3265804-3266466 (Clockwise)

Preceding gene: 138896799

Following gene: 138896803

Centisome position: 91.99

GC content: 48.11

Gene sequence:

>663_bases
ATGAACCTCCGCTACAAATGGACTCCGTTCCTAGCGTACGGACAAAGGCTTGAGCTGAAGAAAAACACGGTCGTATACCG
ACAAGGGGAAGACGGGAAAGGATTTTACTACCTAGACCAAGGGAGTGTAAAAATCAGCACTCTCTCCTCCAACGGCTTCG
AACGCGTGATTGATTATGTACCGGTCGGCACACTCTTGGGTGAACATGGAGCCTGCCGGGGCACGTACCTGACAACTGCA
ATCACGACCGCCCCAACCATTTTGTATTATTTCAGCGATGAAGCGCTCACCCGGGTATGCCAAGATCACCCAGAAGCAGC
CCTTCTGTTTTCCCATTCCCATATCTACAAAGTTCGGCTACTTGCTGAGATCATCGCCTATATGGATTGCTCGGTTGAAC
AACAGATGGCCCACTTTCTGCTTAAACTAGTAGACATTCATGGAAAGGAGACAATTCCCATTGATCAAGCATCGCTGGCC
CGCTATATTGGCACTTCACGAATCACGGTCAACAAAGTGATGCAGAAGTGGCGCAAGCAGGGTCTGATCCGTTGTGGCAA
CAGCATTATTTATGTGTTGGATACTAGCAGACTAAAGAAGCTGCTCCCCTGCACAGAAAATGAGTGTTTAAATAATCAAA
GGAGTAGGAGAGGACACATCTAA

Upstream 100 bases:

>100_bases
TCCATGAAAAAGCCACGATTACGTGATTGTGTGATTGTTGTGGAATAAACCTTTGATAATATATATCTTCACTTAATAAT
TAAAGAAGGTGGTGACCGAG

Downstream 100 bases:

>100_bases
CTATAAACTTCCACATTGGAAGCTTTTGCACATCGATTTGATCGACTGTCGGACAACCGAACAACGCCACTTTCAGCTCC
ATGTAATGGGTCAATGAAAC

Product: cyclic AMP receptor protein regulatory protein CRP

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator Crp/Fnr Family; Cyclic AMP Receptor Protein Regulatory Protein CRP

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNLRYKWTPFLAYGQRLELKKNTVVYRQGEDGKGFYYLDQGSVKISTLSSNGFERVIDYVPVGTLLGEHGACRGTYLTTA
ITTAPTILYYFSDEALTRVCQDHPEAALLFSHSHIYKVRLLAEIIAYMDCSVEQQMAHFLLKLVDIHGKETIPIDQASLA
RYIGTSRITVNKVMQKWRKQGLIRCGNSIIYVLDTSRLKKLLPCTENECLNNQRSRRGHI

Sequences:

>Translated_220_residues
MNLRYKWTPFLAYGQRLELKKNTVVYRQGEDGKGFYYLDQGSVKISTLSSNGFERVIDYVPVGTLLGEHGACRGTYLTTA
ITTAPTILYYFSDEALTRVCQDHPEAALLFSHSHIYKVRLLAEIIAYMDCSVEQQMAHFLLKLVDIHGKETIPIDQASLA
RYIGTSRITVNKVMQKWRKQGLIRCGNSIIYVLDTSRLKKLLPCTENECLNNQRSRRGHI
>Mature_220_residues
MNLRYKWTPFLAYGQRLELKKNTVVYRQGEDGKGFYYLDQGSVKISTLSSNGFERVIDYVPVGTLLGEHGACRGTYLTTA
ITTAPTILYYFSDEALTRVCQDHPEAALLFSHSHIYKVRLLAEIIAYMDCSVEQQMAHFLLKLVDIHGKETIPIDQASLA
RYIGTSRITVNKVMQKWRKQGLIRCGNSIIYVLDTSRLKKLLPCTENECLNNQRSRRGHI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25127; Mature: 25127

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRYKWTPFLAYGQRLELKKNTVVYRQGEDGKGFYYLDQGSVKISTLSSNGFERVIDYV
CCCCEECCHHHHCCCEEEEECCEEEEEECCCCCEEEEEECCCEEEEEECCCCHHHHHHHC
PVGTLLGEHGACRGTYLTTAITTAPTILYYFSDEALTRVCQDHPEAALLFSHSHIYKVRL
CHHHHHCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHHCCCCEEEEEECCHHHHHHH
LAEIIAYMDCSVEQQMAHFLLKLVDIHGKETIPIDQASLARYIGTSRITVNKVMQKWRKQ
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHC
GLIRCGNSIIYVLDTSRLKKLLPCTENECLNNQRSRRGHI
CHHHCCCEEEEEEEHHHHHHHCCCCCHHHHCCHHHHCCCC
>Mature Secondary Structure
MNLRYKWTPFLAYGQRLELKKNTVVYRQGEDGKGFYYLDQGSVKISTLSSNGFERVIDYV
CCCCEECCHHHHCCCEEEEECCEEEEEECCCCCEEEEEECCCEEEEEECCCCHHHHHHHC
PVGTLLGEHGACRGTYLTTAITTAPTILYYFSDEALTRVCQDHPEAALLFSHSHIYKVRL
CHHHHHCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHHCCCCEEEEEECCHHHHHHH
LAEIIAYMDCSVEQQMAHFLLKLVDIHGKETIPIDQASLARYIGTSRITVNKVMQKWRKQ
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHC
GLIRCGNSIIYVLDTSRLKKLLPCTENECLNNQRSRRGHI
CHHHCCCEEEEEEEHHHHHHHCCCCCHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA