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The map label for this gene is yusP [H]

Identifier: 138896756

GI number: 138896756

Start: 3219257

End: 3220864

Strand: Reverse

Name: yusP [H]

Synonym: GTNG_3119

Alternate gene names: 138896756

Gene position: 3220864-3219257 (Counterclockwise)

Preceding gene: 138896757

Following gene: 138896752

Centisome position: 90.72

GC content: 52.05

Gene sequence:

>1608_bases
ATGGAAAAAGCATTAGCAGCGCCAGCAAGTACGATCCGGCATCGTCCGCTGCTTATTACGGGACTCATTATCGCTATGTT
GTTTGCAGCACTTGAAGGGACGATCGTCGGAACAGCGATGCCGCGCATCGTGGGAGAGCTCGGCGGGCTTGGCGTGATGA
CATGGCTGACGACAGCGTATATGTTGACATCGACGACTGTCGTGCCGATCGCTGGTAAGCTCGCCGACTTGCTTGGACGG
CGTCTCGTGTATGTGAGTGGACTTGTCATTTTTATGGCCGGCTCTGCACTTTGTGGCATGGCCAACGATATGACCCAGCT
TATTATTTACCGCGGCATTCAAGGAATCGGCGGCGGAATTATGATGCCGATGGCGATGATTGTCGTTGGTGACGTGTTTA
CGGGGAAAGAGCGTGCGAAATGGCAAGGGGTGTTCGGCGGTTTGTACGGCCTTGCTTCAGTGCTAGGTCCACAAATCGGC
GGCTTTATCGTTGACCATTTGAACTGGCGTTGGGTGTTTTATATTAACTTGCCGGTTGGTATTTTAGCAACAGTGCTGAT
CGCGATGGGCTTAAGCAAATATAAAGCTGAAGGGCCGGTGAAATTTGACGTTGCCGGAATGGCGACGCTGACGGCGGGAG
TCGTCAGCTTGTTGCTTGGGTTGACGTTTGGCGGTGACCAATATGCGTGGGGCTCATGGCAAATCATCTCGCTGTTTGCG
GCGGCGGTGATCTTTTTCGCCTTGTTCATTTGGGCAGAAAAACGGGCTGACGAGCCGATCATCCCGCTTTGGCTCTTTCG
CAATCGGACGTTTACGTTGTTGAACGGCATCGGCTTTTTCATGAGCGTCGGCATGTTCGGAGCCATTATGTTTGTTCCGT
TTTTTATGCAAGGCGTGGTTGGGGTGAGCGCCACAGAGTCAGGAACGATCATGACACCGATGATGGTTACGATGATTATC
GGCAGTGTCGTTGGCGGTCGACTCGTCTACCGAATTGGCGTGAAAACACAGCTGATCATCGGTATGGCCATTATGTTGGC
GGCGTTCGGTTTGCTTGGCACGATGGATGTCGATACGTCCAAATGGACAGCAACAGTATATATGATCATACTCGGGCTCG
GCACAGGGCTTGTGATGCCGATTTTAACGCTCGCTTTGCAAGAAAGCTTTCCAAAATCGGAGCTTGGCGTGGTGACGTCT
TCAAGCCAATTTTTCCGCTCAATCGGCGGGACATTTGGCATGACCGTTCTTGGCGCCATCATGAACCATCGCTCAAGCGC
TTTGCTTGATGAACGATTGATGCCAAAGCTTGAAGCGTTGCCGGCACAGGCGCAAGGGCTTGTTGACCGATTTGCGGATA
TGATTCATAACGATCCGCAAGGGCTGTATTCCGTCTTGCTTAGCCCGGAAGCGATGAAGAATATTCCGGCCGCACTGCGC
GACATGTTCGTGCCGGTATTGAAACAGTCACTCGTTGATTCACTGCAAGCTGTCTTTTTGTTTGGGCTTGTGTTTATTGC
GGTGGGCTTGCTGTTCGTGTTCGGCTTAAAGCGGATTACGCTTTCCGACCGGGACGAGGCGATGAAAAAGATGAAGCAGG
CCGAATAA

Upstream 100 bases:

>100_bases
ATTTGCGCCATCAACAAGCGCCCTCACTTGCGGCGGCCTTGGCCGAGCTGAGCCAAGAAATTAAAACGTATCAACAATTG
AATGGATAGGAGAGAGACAG

Downstream 100 bases:

>100_bases
AAGAAAAAACTCCGCGACAGGCGGAGGAGAATGAAAGTGAAGGACCGTGTCGATTGGAATCGGCACGGTCCTTTTGTATG
TCTAGCAGGGGGCATCCTGA

Product: multidrug resistance protein B

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MEKALAAPASTIRHRPLLITGLIIAMLFAALEGTIVGTAMPRIVGELGGLGVMTWLTTAYMLTSTTVVPIAGKLADLLGR
RLVYVSGLVIFMAGSALCGMANDMTQLIIYRGIQGIGGGIMMPMAMIVVGDVFTGKERAKWQGVFGGLYGLASVLGPQIG
GFIVDHLNWRWVFYINLPVGILATVLIAMGLSKYKAEGPVKFDVAGMATLTAGVVSLLLGLTFGGDQYAWGSWQIISLFA
AAVIFFALFIWAEKRADEPIIPLWLFRNRTFTLLNGIGFFMSVGMFGAIMFVPFFMQGVVGVSATESGTIMTPMMVTMII
GSVVGGRLVYRIGVKTQLIIGMAIMLAAFGLLGTMDVDTSKWTATVYMIILGLGTGLVMPILTLALQESFPKSELGVVTS
SSQFFRSIGGTFGMTVLGAIMNHRSSALLDERLMPKLEALPAQAQGLVDRFADMIHNDPQGLYSVLLSPEAMKNIPAALR
DMFVPVLKQSLVDSLQAVFLFGLVFIAVGLLFVFGLKRITLSDRDEAMKKMKQAE

Sequences:

>Translated_535_residues
MEKALAAPASTIRHRPLLITGLIIAMLFAALEGTIVGTAMPRIVGELGGLGVMTWLTTAYMLTSTTVVPIAGKLADLLGR
RLVYVSGLVIFMAGSALCGMANDMTQLIIYRGIQGIGGGIMMPMAMIVVGDVFTGKERAKWQGVFGGLYGLASVLGPQIG
GFIVDHLNWRWVFYINLPVGILATVLIAMGLSKYKAEGPVKFDVAGMATLTAGVVSLLLGLTFGGDQYAWGSWQIISLFA
AAVIFFALFIWAEKRADEPIIPLWLFRNRTFTLLNGIGFFMSVGMFGAIMFVPFFMQGVVGVSATESGTIMTPMMVTMII
GSVVGGRLVYRIGVKTQLIIGMAIMLAAFGLLGTMDVDTSKWTATVYMIILGLGTGLVMPILTLALQESFPKSELGVVTS
SSQFFRSIGGTFGMTVLGAIMNHRSSALLDERLMPKLEALPAQAQGLVDRFADMIHNDPQGLYSVLLSPEAMKNIPAALR
DMFVPVLKQSLVDSLQAVFLFGLVFIAVGLLFVFGLKRITLSDRDEAMKKMKQAE
>Mature_535_residues
MEKALAAPASTIRHRPLLITGLIIAMLFAALEGTIVGTAMPRIVGELGGLGVMTWLTTAYMLTSTTVVPIAGKLADLLGR
RLVYVSGLVIFMAGSALCGMANDMTQLIIYRGIQGIGGGIMMPMAMIVVGDVFTGKERAKWQGVFGGLYGLASVLGPQIG
GFIVDHLNWRWVFYINLPVGILATVLIAMGLSKYKAEGPVKFDVAGMATLTAGVVSLLLGLTFGGDQYAWGSWQIISLFA
AAVIFFALFIWAEKRADEPIIPLWLFRNRTFTLLNGIGFFMSVGMFGAIMFVPFFMQGVVGVSATESGTIMTPMMVTMII
GSVVGGRLVYRIGVKTQLIIGMAIMLAAFGLLGTMDVDTSKWTATVYMIILGLGTGLVMPILTLALQESFPKSELGVVTS
SSQFFRSIGGTFGMTVLGAIMNHRSSALLDERLMPKLEALPAQAQGLVDRFADMIHNDPQGLYSVLLSPEAMKNIPAALR
DMFVPVLKQSLVDSLQAVFLFGLVFIAVGLLFVFGLKRITLSDRDEAMKKMKQAE

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=450, Percent_Identity=28.2222222222222, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1790195, Length=335, Percent_Identity=29.2537313432836, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1788710, Length=497, Percent_Identity=25.1509054325956, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081983, Length=417, Percent_Identity=26.1390887290168, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788392, Length=305, Percent_Identity=29.8360655737705, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790146, Length=188, Percent_Identity=26.063829787234, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=508, Percent_Identity=26.7716535433071, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323735, Length=516, Percent_Identity=24.4186046511628, Blast_Score=133, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6319770, Length=415, Percent_Identity=26.7469879518072, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319783, Length=483, Percent_Identity=26.5010351966874, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325455, Length=248, Percent_Identity=29.4354838709677, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321663, Length=242, Percent_Identity=27.6859504132231, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324954, Length=374, Percent_Identity=25.1336898395722, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 57508; Mature: 57508

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKALAAPASTIRHRPLLITGLIIAMLFAALEGTIVGTAMPRIVGELGGLGVMTWLTTAY
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
MLTSTTVVPIAGKLADLLGRRLVYVSGLVIFMAGSALCGMANDMTQLIIYRGIQGIGGGI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHH
MMPMAMIVVGDVFTGKERAKWQGVFGGLYGLASVLGPQIGGFIVDHLNWRWVFYINLPVG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHCCHHHHCCCEEEEEEEECCHH
ILATVLIAMGLSKYKAEGPVKFDVAGMATLTAGVVSLLLGLTFGGDQYAWGSWQIISLFA
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AAVIFFALFIWAEKRADEPIIPLWLFRNRTFTLLNGIGFFMSVGMFGAIMFVPFFMQGVV
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSATESGTIMTPMMVTMIIGSVVGGRLVYRIGVKTQLIIGMAIMLAAFGLLGTMDVDTS
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCC
KWTATVYMIILGLGTGLVMPILTLALQESFPKSELGVVTSSSQFFRSIGGTFGMTVLGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCHHHHHHHHHH
MNHRSSALLDERLMPKLEALPAQAQGLVDRFADMIHNDPQGLYSVLLSPEAMKNIPAALR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHH
DMFVPVLKQSLVDSLQAVFLFGLVFIAVGLLFVFGLKRITLSDRDEAMKKMKQAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEKALAAPASTIRHRPLLITGLIIAMLFAALEGTIVGTAMPRIVGELGGLGVMTWLTTAY
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
MLTSTTVVPIAGKLADLLGRRLVYVSGLVIFMAGSALCGMANDMTQLIIYRGIQGIGGGI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHH
MMPMAMIVVGDVFTGKERAKWQGVFGGLYGLASVLGPQIGGFIVDHLNWRWVFYINLPVG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHCCHHHHCCCEEEEEEEECCHH
ILATVLIAMGLSKYKAEGPVKFDVAGMATLTAGVVSLLLGLTFGGDQYAWGSWQIISLFA
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AAVIFFALFIWAEKRADEPIIPLWLFRNRTFTLLNGIGFFMSVGMFGAIMFVPFFMQGVV
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSATESGTIMTPMMVTMIIGSVVGGRLVYRIGVKTQLIIGMAIMLAAFGLLGTMDVDTS
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCC
KWTATVYMIILGLGTGLVMPILTLALQESFPKSELGVVTSSSQFFRSIGGTFGMTVLGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCHHHHHHHHHH
MNHRSSALLDERLMPKLEALPAQAQGLVDRFADMIHNDPQGLYSVLLSPEAMKNIPAALR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHH
DMFVPVLKQSLVDSLQAVFLFGLVFIAVGLLFVFGLKRITLSDRDEAMKKMKQAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]