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The map label for this gene is lytF [H]

Identifier: 138896743

GI number: 138896743

Start: 3207313

End: 3209196

Strand: Reverse

Name: lytF [H]

Synonym: GTNG_3106

Alternate gene names: 138896743

Gene position: 3209196-3207313 (Counterclockwise)

Preceding gene: 138896744

Following gene: 138896741

Centisome position: 90.39

GC content: 50.21

Gene sequence:

>1884_bases
ATGAAAGTGAAGTCGAGCAAAGTCGTATTAGCCACCGCCTTTGCCTCTGCGCTTTTTTTGGCACCAGACGATAGCCAAGC
AGCGGAATGGAAAGTAGGCATGAGTTCCTCAAAAGTAAAAGAGTTGCAGCAGTTATTAAAGGAAAAAGGGTTTTTTTCTT
ACCCACAGGCAACTGGCTATTTTGGTCCCATTACCGAAGAGGCAGTGCGGGCGTTTCAAAAGGCTGCGAACCTGCCGGTG
ACCGGTGTTGTCGATGACGCGACCTACGCGAAGCTACGTGCGTTTGTCCCAACGGCTCGCACGTTATCCGTCGGCATGCG
CGGTGACGATGTGAAAGTGCTCCAACAGCGGCTCAAACAGCTTGGCTACTTTAAATACCCGGAGATTACCGGTTATTTCG
GAACAGTGACCGAAGCGGCCGTGAAGCAATTTCAACAAGCGAATGGGCTTAAGGTCACTGGAAAAGCTGATGCCGTGACG
ATTGAACGCCTTCGGCAAGCAGCTAGCAAACAGGCAACTACCACATCGTCTTCATCAGTCACGTTAAAAATCGGTTCACG
TGGTTCCGAGGTCAGTGAGCTGCAAAAAAACTTAAAGCTACTCGGCTATTTTACCTACCCAACAGCTACCGGCTATTATG
GAACCATTACCGCTGACGCCGTCCGTCGTTTTCAAAAGGACAACGGCTTGCCAGCGACCGGCTCGGTCGATTCAACAACG
CTCGGGCGCATTGCGGATGCGGTGAAGAAAAAAACAGCCCCGCCGGCTAAAGAAAACAGTTCTTCTGTTTATTTAAAGAT
CGGCACGCGTGGGGAAAAGGTGAAGCAGGTTCAAACGAATTTAAAACAGCTTGGCTATTTTACATATCCGGAGATCACCG
GTTATTACGGAACCATTACCGCTGATGCTGTCCGTCGTTTTCAAAAGGACAACGGCTTGCCAGTGACCGGCTCGGTCGAT
TCAACAACGTTCGGACGCATTGAAGATGCGGTGAAGAAAAAAACAGCCTCGCCGGCTAAAGAAAGCAGTTCTTCTGTTTA
TTTAAAGACCGGTACGCGTGGGGAAAAGGTGAAGCAGGTTCAAACGAATTTAAAACAGCTTGGCTATTTTACATATCCGG
AGATCACCGGTTATTACGGAACCATTACCGCTGATGCTGTTCGTCGTTTTCAAAAGGACAACGGCCTGCCAGTGACCGGC
TCGGTCGATTCAACAACGTTCGGGCGCATTGAAGATGCGGTGAAGAAAAAAACAGCCCCGCCGGCCGAAGAAAACCGCAC
TTCCATTTATTTGACGATCGGTACGCGTGGCGAAGAGGTGAAGCGGGTTCAGACGAAATTAAAACAGCTTGGTTATTTTA
CATATCCGGAGATCACCGGTTATTACGGAACCATTACCGCTGACGCTGTCCGTCGTTTCCAGAAGGATGCCAAACTTCAG
GCGAACGGCATCGTCGATAGCCAAACGTACGAACGTCTCATCGGACAAGCTCCAGCATCCAAAGGTCAAGCCTCAGCGTC
CAAACTCGATGTCATGGAACTGATTGCTGATGCGGCTGAGCTGCTCGGCAAGCCATACGTTTGGGGCGGTGAAACTCCGC
AGGTTGGCTTTGACTGCAGTGGATTCATCTACTATTTGTTCGCCCAGCAAGGCATTTCGTTGCCGCGGACGGTAGCGGAC
ATTTGGAACGTCGGGAAACCCGTCTCCTCTCCAGCGGTTGGAGACATCGTGTTTTTTGAGACATATAAAAAAGGACCTTC
TCACGCTGGCATCTATATCGGCAATGGCCAGTTCATCCATAGCGGTAGTTCGACGGGTGTGACGATCAGCCGCCTTGACC
AATCGTATTGGAAGCAACGGTATTTAGGAGCAAAGCGGTATTAG

Upstream 100 bases:

>100_bases
GAAAAATATGCTCTGTTTGTCGGATTTCTCCGCCAAACGGCACACTCGCCGCCGCCAGCGGCAGAAAGAAAAGAGCGAAA
AAACAGGGAAGGGAGAGGGA

Downstream 100 bases:

>100_bases
TGCATGAACCGACTCTTTCGAAGGCCCTTCCGCTGCTCGGAAAATGGATGGCGTGACTAGCAAAAAAGCGCTGGTTTTTC
TAGAGCCACGAATACTTGGA

Product: cell wall lytic activity

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP49; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MKVKSSKVVLATAFASALFLAPDDSQAAEWKVGMSSSKVKELQQLLKEKGFFSYPQATGYFGPITEEAVRAFQKAANLPV
TGVVDDATYAKLRAFVPTARTLSVGMRGDDVKVLQQRLKQLGYFKYPEITGYFGTVTEAAVKQFQQANGLKVTGKADAVT
IERLRQAASKQATTTSSSSVTLKIGSRGSEVSELQKNLKLLGYFTYPTATGYYGTITADAVRRFQKDNGLPATGSVDSTT
LGRIADAVKKKTAPPAKENSSSVYLKIGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTGSVD
STTFGRIEDAVKKKTASPAKESSSSVYLKTGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTG
SVDSTTFGRIEDAVKKKTAPPAEENRTSIYLTIGTRGEEVKRVQTKLKQLGYFTYPEITGYYGTITADAVRRFQKDAKLQ
ANGIVDSQTYERLIGQAPASKGQASASKLDVMELIADAAELLGKPYVWGGETPQVGFDCSGFIYYLFAQQGISLPRTVAD
IWNVGKPVSSPAVGDIVFFETYKKGPSHAGIYIGNGQFIHSGSSTGVTISRLDQSYWKQRYLGAKRY

Sequences:

>Translated_627_residues
MKVKSSKVVLATAFASALFLAPDDSQAAEWKVGMSSSKVKELQQLLKEKGFFSYPQATGYFGPITEEAVRAFQKAANLPV
TGVVDDATYAKLRAFVPTARTLSVGMRGDDVKVLQQRLKQLGYFKYPEITGYFGTVTEAAVKQFQQANGLKVTGKADAVT
IERLRQAASKQATTTSSSSVTLKIGSRGSEVSELQKNLKLLGYFTYPTATGYYGTITADAVRRFQKDNGLPATGSVDSTT
LGRIADAVKKKTAPPAKENSSSVYLKIGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTGSVD
STTFGRIEDAVKKKTASPAKESSSSVYLKTGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTG
SVDSTTFGRIEDAVKKKTAPPAEENRTSIYLTIGTRGEEVKRVQTKLKQLGYFTYPEITGYYGTITADAVRRFQKDAKLQ
ANGIVDSQTYERLIGQAPASKGQASASKLDVMELIADAAELLGKPYVWGGETPQVGFDCSGFIYYLFAQQGISLPRTVAD
IWNVGKPVSSPAVGDIVFFETYKKGPSHAGIYIGNGQFIHSGSSTGVTISRLDQSYWKQRYLGAKRY
>Mature_627_residues
MKVKSSKVVLATAFASALFLAPDDSQAAEWKVGMSSSKVKELQQLLKEKGFFSYPQATGYFGPITEEAVRAFQKAANLPV
TGVVDDATYAKLRAFVPTARTLSVGMRGDDVKVLQQRLKQLGYFKYPEITGYFGTVTEAAVKQFQQANGLKVTGKADAVT
IERLRQAASKQATTTSSSSVTLKIGSRGSEVSELQKNLKLLGYFTYPTATGYYGTITADAVRRFQKDNGLPATGSVDSTT
LGRIADAVKKKTAPPAKENSSSVYLKIGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTGSVD
STTFGRIEDAVKKKTASPAKESSSSVYLKTGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTG
SVDSTTFGRIEDAVKKKTAPPAEENRTSIYLTIGTRGEEVKRVQTKLKQLGYFTYPEITGYYGTITADAVRRFQKDAKLQ
ANGIVDSQTYERLIGQAPASKGQASASKLDVMELIADAAELLGKPYVWGGETPQVGFDCSGFIYYLFAQQGISLPRTVAD
IWNVGKPVSSPAVGDIVFFETYKKGPSHAGIYIGNGQFIHSGSSTGVTISRLDQSYWKQRYLGAKRY

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=129, Percent_Identity=38.7596899224806, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788501, Length=135, Percent_Identity=40.7407407407407, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786421, Length=112, Percent_Identity=38.3928571428571, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788001, Length=135, Percent_Identity=34.0740740740741, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 68320; Mature: 68320

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKSSKVVLATAFASALFLAPDDSQAAEWKVGMSSSKVKELQQLLKEKGFFSYPQATGY
CCCCCCCEEEEEEHHHHEEECCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
FGPITEEAVRAFQKAANLPVTGVVDDATYAKLRAFVPTARTLSVGMRGDDVKVLQQRLKQ
CCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHH
LGYFKYPEITGYFGTVTEAAVKQFQQANGLKVTGKADAVTIERLRQAASKQATTTSSSSV
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEE
TLKIGSRGSEVSELQKNLKLLGYFTYPTATGYYGTITADAVRRFQKDNGLPATGSVDSTT
EEEECCCCCHHHHHHHCCEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHH
LGRIADAVKKKTAPPAKENSSSVYLKIGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTIT
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCCCEEEEE
ADAVRRFQKDNGLPVTGSVDSTTFGRIEDAVKKKTASPAKESSSSVYLKTGTRGEKVKQV
HHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHH
QTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTGSVDSTTFGRIEDAVKKKTAP
HHHHHHCCCEECCCCCCCEEEEEHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCC
PAEENRTSIYLTIGTRGEEVKRVQTKLKQLGYFTYPEITGYYGTITADAVRRFQKDAKLQ
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCEE
ANGIVDSQTYERLIGQAPASKGQASASKLDVMELIADAAELLGKPYVWGGETPQVGFDCS
ECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GFIYYLFAQQGISLPRTVADIWNVGKPVSSPAVGDIVFFETYKKGPSHAGIYIGNGQFIH
HHHHHEEHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEHHCCCCCCCCEEECCCEEEE
SGSSTGVTISRLDQSYWKQRYLGAKRY
CCCCCCEEHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKVKSSKVVLATAFASALFLAPDDSQAAEWKVGMSSSKVKELQQLLKEKGFFSYPQATGY
CCCCCCCEEEEEEHHHHEEECCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
FGPITEEAVRAFQKAANLPVTGVVDDATYAKLRAFVPTARTLSVGMRGDDVKVLQQRLKQ
CCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHH
LGYFKYPEITGYFGTVTEAAVKQFQQANGLKVTGKADAVTIERLRQAASKQATTTSSSSV
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEE
TLKIGSRGSEVSELQKNLKLLGYFTYPTATGYYGTITADAVRRFQKDNGLPATGSVDSTT
EEEECCCCCHHHHHHHCCEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHH
LGRIADAVKKKTAPPAKENSSSVYLKIGTRGEKVKQVQTNLKQLGYFTYPEITGYYGTIT
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCCCEEEEE
ADAVRRFQKDNGLPVTGSVDSTTFGRIEDAVKKKTASPAKESSSSVYLKTGTRGEKVKQV
HHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHH
QTNLKQLGYFTYPEITGYYGTITADAVRRFQKDNGLPVTGSVDSTTFGRIEDAVKKKTAP
HHHHHHCCCEECCCCCCCEEEEEHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCC
PAEENRTSIYLTIGTRGEEVKRVQTKLKQLGYFTYPEITGYYGTITADAVRRFQKDAKLQ
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCEE
ANGIVDSQTYERLIGQAPASKGQASASKLDVMELIADAAELLGKPYVWGGETPQVGFDCS
ECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GFIYYLFAQQGISLPRTVADIWNVGKPVSSPAVGDIVFFETYKKGPSHAGIYIGNGQFIH
HHHHHEEHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEHHCCCCCCCCEEECCCEEEE
SGSSTGVTISRLDQSYWKQRYLGAKRY
CCCCCCEEHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10206711 [H]