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The map label for this gene is pgi [H]

Identifier: 138896514

GI number: 138896514

Start: 2987238

End: 2988587

Strand: Reverse

Name: pgi [H]

Synonym: GTNG_2877

Alternate gene names: 138896514

Gene position: 2988587-2987238 (Counterclockwise)

Preceding gene: 138896515

Following gene: 138896513

Centisome position: 84.18

GC content: 50.96

Gene sequence:

>1350_bases
ATGACCCATATTCGTTTCGACTATTCCAAAGCGCTCGCTTTTTTTGGTGAACACGAACTTACATACTTGCGCGATGCGGT
GAAAGTCGCACACCATTCGCTCCATGAAAAAACTGGAGTCGGCAATGACTTTTTAGGATGGTTAGACTGGCCGGTCAACT
ATGACAAAGAAGAATTTGCGCGCATCAAGCAAGCGGCGAAAAAAATTCAATCAGACTCCGATGTCCTTCTTGTCATCGGT
ATCGGTGGCTCGTATCTCGGGGCGCGTGCGGCGATTGAGATGCTGCATCATTCGTTTTACAACGCCTTGCCGAAAGAGAA
GCGGTCCACACCGCAAATCATCTTTGTCGGCAACAACATCAGCTCGACGTATATGAAAGATGTCATTGATTTCCTTGAAG
GAAAAGACTTCTCGATTAACGTCATTTCCAAATCGGGAACGACGACTGAGCCGGCGATCGCTTTCCGTATTTTCCGCAAG
CTGCTTGAAGACAAATACGGCAAAGAAGAAGCACGCCGCCGCATTTACGCAACGACCGACCGTGCACGCGGCGCACTGCG
GACGCTCGCTGACGAGGAAGGATACGAAACGTTTGTGATTCCGGATGACATCGGCGGTCGCTATTCAGTGTTGACGGCGG
TTGGATTGCTGCCGATCGCTGCCAGCGGCGCTGACATCGACGCCATGATGGAAGGGGCAGCGAAGGCGCGCGAAGACTTC
AGCCGCTCGGAGCTCGAAGAAAACGCAGCTTACCAATATGCGGCCATTCGCAACATTTTGTACAACAAAGGAAAAACGAT
CGAGTTGCTCGTTAACTACGAACCAGCCTTGCACTATTTCGCTGAATGGTGGAAGCAGCTGTTCGGCGAAAGCGAAGGGA
AAGACCAAAAAGGCATTTATCCGGCTTCGGCTGACTTCTCGACCGACTTGCATTCGCTCGGCCAATACATTCAAGAAGGT
CGCCGTGATTTGTTTGAAACGGTGCTGAAACTTGAAGAGCCGCGCCATGAATTGGTCATCGAAGCGGAAGAAAGCGACTT
AGACGGGCTGAACTATTTAGCCGGCCAAACGGTCGATTTCGTCAACACGAAAGCGTTCGAAGGGACGCTTCTCGCCCATA
CGGACGGCGGCGTGCCGAATTTGGTTGTCACTTTGCCGAAGCTTGATGAATACACGTTTGGCTATCTCGTTTACTTCTTT
GAAAAGGCATGCGCCATGAGCGGCTATTTGCTCGGGGTGAACCCGTTTGACCAGCCAGGTGTTGAGGCGTACAAGAAAAA
CATGTTCGCCCTCTTAGGCAAACCGGGTTACGAAGAGCTGAAAGACGAACTGGAGAAACGGTTGAAATAA

Upstream 100 bases:

>100_bases
GAATTGAATCCGTTTTCAATTGAGAGCATCGCTTGATTTCCCTTGCCCGTTCCGCTAAAGTGAAAGAAGGCAATGATTAT
TGAATGGGAGGAAGAATTGA

Downstream 100 bases:

>100_bases
CAAAAGGATGGTCAAGCCGCTTTTTCTCGGCATGTACGGCCGGTTTCGGCCGCATTTTCCAGAGTGAATCGAAACGAACA
ACGCCTCTTCTCCTTTAGTC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI A; Phosphoglucose isomerase A; PGI-A; Phosphohexose isomerase A; PHI-A [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTHIRFDYSKALAFFGEHELTYLRDAVKVAHHSLHEKTGVGNDFLGWLDWPVNYDKEEFARIKQAAKKIQSDSDVLLVIG
IGGSYLGARAAIEMLHHSFYNALPKEKRSTPQIIFVGNNISSTYMKDVIDFLEGKDFSINVISKSGTTTEPAIAFRIFRK
LLEDKYGKEEARRRIYATTDRARGALRTLADEEGYETFVIPDDIGGRYSVLTAVGLLPIAASGADIDAMMEGAAKAREDF
SRSELEENAAYQYAAIRNILYNKGKTIELLVNYEPALHYFAEWWKQLFGESEGKDQKGIYPASADFSTDLHSLGQYIQEG
RRDLFETVLKLEEPRHELVIEAEESDLDGLNYLAGQTVDFVNTKAFEGTLLAHTDGGVPNLVVTLPKLDEYTFGYLVYFF
EKACAMSGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEELKDELEKRLK

Sequences:

>Translated_449_residues
MTHIRFDYSKALAFFGEHELTYLRDAVKVAHHSLHEKTGVGNDFLGWLDWPVNYDKEEFARIKQAAKKIQSDSDVLLVIG
IGGSYLGARAAIEMLHHSFYNALPKEKRSTPQIIFVGNNISSTYMKDVIDFLEGKDFSINVISKSGTTTEPAIAFRIFRK
LLEDKYGKEEARRRIYATTDRARGALRTLADEEGYETFVIPDDIGGRYSVLTAVGLLPIAASGADIDAMMEGAAKAREDF
SRSELEENAAYQYAAIRNILYNKGKTIELLVNYEPALHYFAEWWKQLFGESEGKDQKGIYPASADFSTDLHSLGQYIQEG
RRDLFETVLKLEEPRHELVIEAEESDLDGLNYLAGQTVDFVNTKAFEGTLLAHTDGGVPNLVVTLPKLDEYTFGYLVYFF
EKACAMSGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEELKDELEKRLK
>Mature_448_residues
THIRFDYSKALAFFGEHELTYLRDAVKVAHHSLHEKTGVGNDFLGWLDWPVNYDKEEFARIKQAAKKIQSDSDVLLVIGI
GGSYLGARAAIEMLHHSFYNALPKEKRSTPQIIFVGNNISSTYMKDVIDFLEGKDFSINVISKSGTTTEPAIAFRIFRKL
LEDKYGKEEARRRIYATTDRARGALRTLADEEGYETFVIPDDIGGRYSVLTAVGLLPIAASGADIDAMMEGAAKAREDFS
RSELEENAAYQYAAIRNILYNKGKTIELLVNYEPALHYFAEWWKQLFGESEGKDQKGIYPASADFSTDLHSLGQYIQEGR
RDLFETVLKLEEPRHELVIEAEESDLDGLNYLAGQTVDFVNTKAFEGTLLAHTDGGVPNLVVTLPKLDEYTFGYLVYFFE
KACAMSGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEELKDELEKRLK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71996703, Length=381, Percent_Identity=25.9842519685039, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71996708, Length=381, Percent_Identity=25.9842519685039, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319673, Length=375, Percent_Identity=25.0666666666667, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 50586; Mature: 50455

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIRFDYSKALAFFGEHELTYLRDAVKVAHHSLHEKTGVGNDFLGWLDWPVNYDKEEFA
CCCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHH
RIKQAAKKIQSDSDVLLVIGIGGSYLGARAAIEMLHHSFYNALPKEKRSTPQIIFVGNNI
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCC
SSTYMKDVIDFLEGKDFSINVISKSGTTTEPAIAFRIFRKLLEDKYGKEEARRRIYATTD
CHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEECCH
RARGALRTLADEEGYETFVIPDDIGGRYSVLTAVGLLPIAASGADIDAMMEGAAKAREDF
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SRSELEENAAYQYAAIRNILYNKGKTIELLVNYEPALHYFAEWWKQLFGESEGKDQKGIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCC
PASADFSTDLHSLGQYIQEGRRDLFETVLKLEEPRHELVIEAEESDLDGLNYLAGQTVDF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCHH
VNTKAFEGTLLAHTDGGVPNLVVTLPKLDEYTFGYLVYFFEKACAMSGYLLGVNPFDQPG
HCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
VEAYKKNMFALLGKPGYEELKDELEKRLK
HHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
THIRFDYSKALAFFGEHELTYLRDAVKVAHHSLHEKTGVGNDFLGWLDWPVNYDKEEFA
CCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHH
RIKQAAKKIQSDSDVLLVIGIGGSYLGARAAIEMLHHSFYNALPKEKRSTPQIIFVGNNI
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCC
SSTYMKDVIDFLEGKDFSINVISKSGTTTEPAIAFRIFRKLLEDKYGKEEARRRIYATTD
CHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEECCH
RARGALRTLADEEGYETFVIPDDIGGRYSVLTAVGLLPIAASGADIDAMMEGAAKAREDF
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SRSELEENAAYQYAAIRNILYNKGKTIELLVNYEPALHYFAEWWKQLFGESEGKDQKGIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCC
PASADFSTDLHSLGQYIQEGRRDLFETVLKLEEPRHELVIEAEESDLDGLNYLAGQTVDF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCHH
VNTKAFEGTLLAHTDGGVPNLVVTLPKLDEYTFGYLVYFFEKACAMSGYLLGVNPFDQPG
HCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
VEAYKKNMFALLGKPGYEELKDELEKRLK
HHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2532320 [H]