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The map label for this gene is dnaC [H]

Identifier: 138896487

GI number: 138896487

Start: 2958211

End: 2959458

Strand: Reverse

Name: dnaC [H]

Synonym: GTNG_2850

Alternate gene names: 138896487

Gene position: 2959458-2958211 (Counterclockwise)

Preceding gene: 138896488

Following gene: 138896486

Centisome position: 83.36

GC content: 50.24

Gene sequence:

>1248_bases
ATGAGCGTCGAGGCAGAAAAAGCAGTGTTAGGGACATTTCTTGAATGTCCCTACCTGCTCAAAGAAACGGTTCTGACCGA
AACGCACTTCAGCGATCCGAAGCACCGGAAACTGTTCGCTGCCATGAAGCGGATCGCACAGCAGGACGAATTGGATATTG
TGACGCTTTCAACGAGAGAAGATGTGGCTAATTTTGGAGGCCTGTCCTATCTCAACGAGATCTCCGCTTTTGCGAACGAA
ACGAAATTCGATCAATACGAAGTGCTGGTTCTCGACGAATGGAAAGAGCGAGAGAAGCGGCGGATTCTTGTTGTGGCGGC
GCAGGAAAATTGGGATGTTGACAAGATCACAACCGCGCTGACCCGTTTAAACGAGGGGCGGATCACCGACCATCATGACA
TCAATGATTTGCTACAAGAGGTAGCCGAAGCGCCGTGGGTGCCGACCGAGCGGAAAAGGGGTGCGCCGTCGGGCATTAGC
GAGCTTGACAAAATGTTGAATGGTTTCAATGATGGCGATTCGATCATTTTGGCAGCGCGACCGTCGATGGGGAAGACCGA
CTTCATGATCCATTTTGCGAAGAGCGTCGGATGGCATGGGTACTTGCCTATCGTGTTTTCGCTTGAAATGGCGGCCGATA
AAATACGCGACCGACTCATCGGTTCGATTGGCGGATTCAATCGGATGAAGTTGCGAAATCCGTATCACGATTTGTCAGAA
GAACAGAAGCGCATGTGGATCGAAGTCATTGGGAAGGCATCCGAAACACACATGCAAATCTTTGACGGCGCCGGACAGAG
TATTGCGGATATTCGTTCGAAAATCAGAAAGTCCATCAATCGATTTCCAGACAGAAAGGCTGTCGTGTTCATTGATTATC
TCACATTGATACGGCCGGAACGATATTACGGCGGAAACATGCATTTGCAAGTCACCGAGATTTCCAGAGCGATCAAGGAG
ACGGCAAAAGAATTCAGTTGTCCAATCATCACACTGGCGCAATTGTCGCGGGATGTAGAGAAACGAAGCGACAAGAGACC
GCTTATGTCGGACATCAGAGAGTCGGGAAGCATTGAGCAAGACGCGGACGTGGTGATCTTTCTATACCGCGACAGCTATT
ACAACGCCGAAGCTGATCCCCGCGTTGCGGAAGTCATTGTGGCTAAGAGCCGCAATGGAGCGGTCGGGACGGTTCGGGTT
TCATACAATCGAAACACGGGGGTGATTCAAGATTTATACCGTTCATGA

Upstream 100 bases:

>100_bases
CTTATCCGCCTACGATCGCCGAACTTTGTCATAGAGAGGAACGGCCAGCTTATTATGAGCTGTATGTTCATAACATGAAC
GCCGGAGAGGACTGGCCACA

Downstream 100 bases:

>100_bases
ACTGATGAAAGAAGCCATTCGTGACGAAGCCGCTTCTCTTATCTATACGCTTCACTATTTTTTGTCCGCAGGACGGATAC
GGCGTGACAGCACGATGGAT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSVEAEKAVLGTFLECPYLLKETVLTETHFSDPKHRKLFAAMKRIAQQDELDIVTLSTREDVANFGGLSYLNEISAFANE
TKFDQYEVLVLDEWKEREKRRILVVAAQENWDVDKITTALTRLNEGRITDHHDINDLLQEVAEAPWVPTERKRGAPSGIS
ELDKMLNGFNDGDSIILAARPSMGKTDFMIHFAKSVGWHGYLPIVFSLEMAADKIRDRLIGSIGGFNRMKLRNPYHDLSE
EQKRMWIEVIGKASETHMQIFDGAGQSIADIRSKIRKSINRFPDRKAVVFIDYLTLIRPERYYGGNMHLQVTEISRAIKE
TAKEFSCPIITLAQLSRDVEKRSDKRPLMSDIRESGSIEQDADVVIFLYRDSYYNAEADPRVAEVIVAKSRNGAVGTVRV
SYNRNTGVIQDLYRS

Sequences:

>Translated_415_residues
MSVEAEKAVLGTFLECPYLLKETVLTETHFSDPKHRKLFAAMKRIAQQDELDIVTLSTREDVANFGGLSYLNEISAFANE
TKFDQYEVLVLDEWKEREKRRILVVAAQENWDVDKITTALTRLNEGRITDHHDINDLLQEVAEAPWVPTERKRGAPSGIS
ELDKMLNGFNDGDSIILAARPSMGKTDFMIHFAKSVGWHGYLPIVFSLEMAADKIRDRLIGSIGGFNRMKLRNPYHDLSE
EQKRMWIEVIGKASETHMQIFDGAGQSIADIRSKIRKSINRFPDRKAVVFIDYLTLIRPERYYGGNMHLQVTEISRAIKE
TAKEFSCPIITLAQLSRDVEKRSDKRPLMSDIRESGSIEQDADVVIFLYRDSYYNAEADPRVAEVIVAKSRNGAVGTVRV
SYNRNTGVIQDLYRS
>Mature_414_residues
SVEAEKAVLGTFLECPYLLKETVLTETHFSDPKHRKLFAAMKRIAQQDELDIVTLSTREDVANFGGLSYLNEISAFANET
KFDQYEVLVLDEWKEREKRRILVVAAQENWDVDKITTALTRLNEGRITDHHDINDLLQEVAEAPWVPTERKRGAPSGISE
LDKMLNGFNDGDSIILAARPSMGKTDFMIHFAKSVGWHGYLPIVFSLEMAADKIRDRLIGSIGGFNRMKLRNPYHDLSEE
QKRMWIEVIGKASETHMQIFDGAGQSIADIRSKIRKSINRFPDRKAVVFIDYLTLIRPERYYGGNMHLQVTEISRAIKET
AKEFSCPIITLAQLSRDVEKRSDKRPLMSDIRESGSIEQDADVVIFLYRDSYYNAEADPRVAEVIVAKSRNGAVGTVRVS
YNRNTGVIQDLYRS

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=433, Percent_Identity=31.8706697459584, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 47298; Mature: 47167

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEAEKAVLGTFLECPYLLKETVLTETHFSDPKHRKLFAAMKRIAQQDELDIVTLSTRE
CCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHH
DVANFGGLSYLNEISAFANETKFDQYEVLVLDEWKEREKRRILVVAAQENWDVDKITTAL
HHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCCEEEEEEECCCCCHHHHHHHH
TRLNEGRITDHHDINDLLQEVAEAPWVPTERKRGAPSGISELDKMLNGFNDGDSIILAAR
HHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEC
PSMGKTDFMIHFAKSVGWHGYLPIVFSLEMAADKIRDRLIGSIGGFNRMKLRNPYHDLSE
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHH
EQKRMWIEVIGKASETHMQIFDGAGQSIADIRSKIRKSINRFPDRKAVVFIDYLTLIRPE
HHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCC
RYYGGNMHLQVTEISRAIKETAKEFSCPIITLAQLSRDVEKRSDKRPLMSDIRESGSIEQ
CCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
DADVVIFLYRDSYYNAEADPRVAEVIVAKSRNGAVGTVRVSYNRNTGVIQDLYRS
CCCEEEEEEECCCCCCCCCCHHHHHEEEECCCCCEEEEEEEECCCCCHHHHHHCC
>Mature Secondary Structure 
SVEAEKAVLGTFLECPYLLKETVLTETHFSDPKHRKLFAAMKRIAQQDELDIVTLSTRE
CCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHH
DVANFGGLSYLNEISAFANETKFDQYEVLVLDEWKEREKRRILVVAAQENWDVDKITTAL
HHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCCEEEEEEECCCCCHHHHHHHH
TRLNEGRITDHHDINDLLQEVAEAPWVPTERKRGAPSGISELDKMLNGFNDGDSIILAAR
HHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEC
PSMGKTDFMIHFAKSVGWHGYLPIVFSLEMAADKIRDRLIGSIGGFNRMKLRNPYHDLSE
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHH
EQKRMWIEVIGKASETHMQIFDGAGQSIADIRSKIRKSINRFPDRKAVVFIDYLTLIRPE
HHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCC
RYYGGNMHLQVTEISRAIKETAKEFSCPIITLAQLSRDVEKRSDKRPLMSDIRESGSIEQ
CCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
DADVVIFLYRDSYYNAEADPRVAEVIVAKSRNGAVGTVRVSYNRNTGVIQDLYRS
CCCEEEEEEECCCCCCCCCCHHHHHEEEECCCCCEEEEEEEECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]