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The map label for this gene is cat1 [H]

Identifier: 138896421

GI number: 138896421

Start: 2901716

End: 2903236

Strand: Reverse

Name: cat1 [H]

Synonym: GTNG_2784

Alternate gene names: 138896421

Gene position: 2903236-2901716 (Counterclockwise)

Preceding gene: 138896422

Following gene: 138896419

Centisome position: 81.77

GC content: 51.74

Gene sequence:

>1521_bases
GTGGAGCAACGCATTTTCGAACGGATCGGCCATCGAGCGTTGAGGGAGAGGATTGTGACAGCGGAAACAGCGGCCTCGTG
GATTCATGACGGCATGACGCTTGGATTAAGCGGTTTTACCCGTGCAGGTGATGCCAAAGCGGTGCCGATGGCACTCATAG
AGAAAGCGAAGCAGCAGCCGCTGAAAGTTGACGTCTATACAGGGGCTTCGCTCGGTTCGGATATTGATAAGCTGATGGCG
GAAGCGGGGATTATTCAGAAACGGTTACCGTTTCAAGCTGACGCGACGATGCGCCGGAAAATCAATGAAAGGGAGCTGCT
GTTTGTTGACCAGCATTTGTCGCATACGGCGGAGCTGGTCCGTTCGGATGTATTGAAACCAATTGATTACGCGATTGTGG
AGGCGGTTTCGATCACCGAAGACGGAATGATCATCCCAACGACTTCTGTCGGCAATTCGTCCGTTTTTGTTAACAAAGCA
AGAAGAGTGATCATTGAATTAAACATGGCTCAGCCGAAAGCGCTGTATGGGTTTCATGACATTTATGAAGTTGGCAAGCA
AGGAGAGCGCGCCCCGATTCCGCTGACCAAAGTGGATGAACGGATTGGAACGATTGGCATTCCGGTAGACATCGCCAAAA
TCGCCGGCATTGTCATTACGAGCCAAACGGATTCGCCATCAACCATTGTACCGCCTGATCAGGAAACGGCGGCGATCGCC
AATCATTTAATCGATTTTCTTCGCGCCGAAGTGGCAGCGGGACGGTTGTCGGAGCGGTTGGCACCGATTCAAGCGGGAAT
CGGTTCGGTCGCGAATGCGGTTCTTTACGGCTTATTAGATTCTGAATTTTATGACTTGGAAGTGTATTCGGAAGTATTGC
AGGACGCCATGTTCGATTTGATTGATGCAGGGAAGGTACGGTTCGCTTCCGGTTGTTCGATGACGTTGTCAGAAAGCAAG
ATGGAACAAGTGTATACAAATTTGGAAGCGTATCAAGGAAAACTCGTTTTGCGACCGCAAGAGATTTCAAACCACCCGGA
AATCATCCGTCGTCTCGGTCTCATTTCGATCAATACGGCACTTGAAGCCGACATTTACGGAAATGTCAACTCGACGCACG
TCCGCGGCACCCAGATGATGAACGGGATCGGCGGCTCGGGTGACTTTGCGCGCCATGCGCGTCTGACGATTTTTGTTACG
AAATCAAGTGCTAAGCAAGGGGCGATTTCGAGCATCGTTCCATTCGTATCGCATGTGGACCATACCGAGCATGATGTCGA
CGTAATTATCACCGAGTACGGATACGCCGACTTGCGCGGGCTGGCTCCTGTGGAACGCGCTCCGTTGATCATTGAACGTT
GCGCCCATCCGGACTACCGCCAGCCGCTGCGCGATTACTTCAACGAAGCGCTTAAGCGCGGCGGCCATACGCCGCACGTC
TTGGAAAAAGCGCTCTCGTGGCATATTCGTTATGAGCAATACGGAACGATGCGGGAAGAACAATATGAGCTGCAACGGTA
A

Upstream 100 bases:

>100_bases
GCTGCTTGAATGCAAAAGAAAGCCCTTTTACTCCCATTCGAATGATTTTCCCCTTGCCGGTCGCTATAATGAGAGAAAAA
AGAAAAAGGGGGAAGTCGCT

Downstream 100 bases:

>100_bases
AACCGTACAAGGTAAACGAAGGAGGGCTTTTTCATCTGCTTTGCCTTGTGTGAGATCGAAAGAGCAACGGCTGATCCAAA
GGAGGATCCTGAGCTTCAAG

Product: succinyl-CoA, coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MEQRIFERIGHRALRERIVTAETAASWIHDGMTLGLSGFTRAGDAKAVPMALIEKAKQQPLKVDVYTGASLGSDIDKLMA
EAGIIQKRLPFQADATMRRKINERELLFVDQHLSHTAELVRSDVLKPIDYAIVEAVSITEDGMIIPTTSVGNSSVFVNKA
RRVIIELNMAQPKALYGFHDIYEVGKQGERAPIPLTKVDERIGTIGIPVDIAKIAGIVITSQTDSPSTIVPPDQETAAIA
NHLIDFLRAEVAAGRLSERLAPIQAGIGSVANAVLYGLLDSEFYDLEVYSEVLQDAMFDLIDAGKVRFASGCSMTLSESK
MEQVYTNLEAYQGKLVLRPQEISNHPEIIRRLGLISINTALEADIYGNVNSTHVRGTQMMNGIGGSGDFARHARLTIFVT
KSSAKQGAISSIVPFVSHVDHTEHDVDVIITEYGYADLRGLAPVERAPLIIERCAHPDYRQPLRDYFNEALKRGGHTPHV
LEKALSWHIRYEQYGTMREEQYELQR

Sequences:

>Translated_506_residues
MEQRIFERIGHRALRERIVTAETAASWIHDGMTLGLSGFTRAGDAKAVPMALIEKAKQQPLKVDVYTGASLGSDIDKLMA
EAGIIQKRLPFQADATMRRKINERELLFVDQHLSHTAELVRSDVLKPIDYAIVEAVSITEDGMIIPTTSVGNSSVFVNKA
RRVIIELNMAQPKALYGFHDIYEVGKQGERAPIPLTKVDERIGTIGIPVDIAKIAGIVITSQTDSPSTIVPPDQETAAIA
NHLIDFLRAEVAAGRLSERLAPIQAGIGSVANAVLYGLLDSEFYDLEVYSEVLQDAMFDLIDAGKVRFASGCSMTLSESK
MEQVYTNLEAYQGKLVLRPQEISNHPEIIRRLGLISINTALEADIYGNVNSTHVRGTQMMNGIGGSGDFARHARLTIFVT
KSSAKQGAISSIVPFVSHVDHTEHDVDVIITEYGYADLRGLAPVERAPLIIERCAHPDYRQPLRDYFNEALKRGGHTPHV
LEKALSWHIRYEQYGTMREEQYELQR
>Mature_506_residues
MEQRIFERIGHRALRERIVTAETAASWIHDGMTLGLSGFTRAGDAKAVPMALIEKAKQQPLKVDVYTGASLGSDIDKLMA
EAGIIQKRLPFQADATMRRKINERELLFVDQHLSHTAELVRSDVLKPIDYAIVEAVSITEDGMIIPTTSVGNSSVFVNKA
RRVIIELNMAQPKALYGFHDIYEVGKQGERAPIPLTKVDERIGTIGIPVDIAKIAGIVITSQTDSPSTIVPPDQETAAIA
NHLIDFLRAEVAAGRLSERLAPIQAGIGSVANAVLYGLLDSEFYDLEVYSEVLQDAMFDLIDAGKVRFASGCSMTLSESK
MEQVYTNLEAYQGKLVLRPQEISNHPEIIRRLGLISINTALEADIYGNVNSTHVRGTQMMNGIGGSGDFARHARLTIFVT
KSSAKQGAISSIVPFVSHVDHTEHDVDVIITEYGYADLRGLAPVERAPLIIERCAHPDYRQPLRDYFNEALKRGGHTPHV
LEKALSWHIRYEQYGTMREEQYELQR

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=485, Percent_Identity=40.6185567010309, Blast_Score=370, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17538151, Length=231, Percent_Identity=29.004329004329, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=520, Percent_Identity=40.7692307692308, Blast_Score=387, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 56027; Mature: 56027

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRIFERIGHRALRERIVTAETAASWIHDGMTLGLSGFTRAGDAKAVPMALIEKAKQQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHCCC
LKVDVYTGASLGSDIDKLMAEAGIIQKRLPFQADATMRRKINERELLFVDQHLSHTAELV
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHH
RSDVLKPIDYAIVEAVSITEDGMIIPTTSVGNSSVFVNKARRVIIELNMAQPKALYGFHD
HHHCCCHHHHHHHHHHEECCCCEEEEECCCCCCCEEHCCCCEEEEEECCCCCHHHHHHHH
IYEVGKQGERAPIPLTKVDERIGTIGIPVDIAKIAGIVITSQTDSPSTIVPPDQETAAIA
HHHHCCCCCCCCCCHHHHHHHHCCCCCCEEHHHHCCEEEEECCCCCCCCCCCCHHHHHHH
NHLIDFLRAEVAAGRLSERLAPIQAGIGSVANAVLYGLLDSEFYDLEVYSEVLQDAMFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IDAGKVRFASGCSMTLSESKMEQVYTNLEAYQGKLVLRPQEISNHPEIIRRLGLISINTA
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCHHHHHHHCCEEECCC
LEADIYGNVNSTHVRGTQMMNGIGGSGDFARHARLTIFVTKSSAKQGAISSIVPFVSHVD
EEEEECCCCCCCEECHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCC
HTEHDVDVIITEYGYADLRGLAPVERAPLIIERCAHPDYRQPLRDYFNEALKRGGHTPHV
CCCCCEEEEEEECCCHHHCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHH
LEKALSWHIRYEQYGTMREEQYELQR
HHHHHHHEEEHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MEQRIFERIGHRALRERIVTAETAASWIHDGMTLGLSGFTRAGDAKAVPMALIEKAKQQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHCCC
LKVDVYTGASLGSDIDKLMAEAGIIQKRLPFQADATMRRKINERELLFVDQHLSHTAELV
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHH
RSDVLKPIDYAIVEAVSITEDGMIIPTTSVGNSSVFVNKARRVIIELNMAQPKALYGFHD
HHHCCCHHHHHHHHHHEECCCCEEEEECCCCCCCEEHCCCCEEEEEECCCCCHHHHHHHH
IYEVGKQGERAPIPLTKVDERIGTIGIPVDIAKIAGIVITSQTDSPSTIVPPDQETAAIA
HHHHCCCCCCCCCCHHHHHHHHCCCCCCEEHHHHCCEEEEECCCCCCCCCCCCHHHHHHH
NHLIDFLRAEVAAGRLSERLAPIQAGIGSVANAVLYGLLDSEFYDLEVYSEVLQDAMFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IDAGKVRFASGCSMTLSESKMEQVYTNLEAYQGKLVLRPQEISNHPEIIRRLGLISINTA
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCHHHHHHHCCEEECCC
LEADIYGNVNSTHVRGTQMMNGIGGSGDFARHARLTIFVTKSSAKQGAISSIVPFVSHVD
EEEEECCCCCCCEECHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCC
HTEHDVDVIITEYGYADLRGLAPVERAPLIIERCAHPDYRQPLRDYFNEALKRGGHTPHV
CCCCCEEEEEEECCCHHHCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHH
LEKALSWHIRYEQYGTMREEQYELQR
HHHHHHHEEEHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]