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The map label for this gene is htrA [H]

Identifier: 138896402

GI number: 138896402

Start: 2879989

End: 2881329

Strand: Direct

Name: htrA [H]

Synonym: GTNG_2765

Alternate gene names: 138896402

Gene position: 2879989-2881329 (Clockwise)

Preceding gene: 138896401

Following gene: 138896405

Centisome position: 81.12

GC content: 51.53

Gene sequence:

>1341_bases
ATGATCACGCTCCCAATCAGCATCATTTTCGCCGTATGCATCGCCGCTTCCTTCTTTCTAATGAACATCAAACCCGACAC
GTCCCACGTCTCACAAGCGCAAAAGCTGGCTGAGTATACAAAGCCAGCCGTCGTCCGTATCGTCGATTATGCGATCGTGG
AATGGAAATTTGTCAACAATGATCCGGATGTCGACGCGTACCTCCACCAGCTTGATTACCGAACGATGATTGGCGCATCC
GGCTCAGGGGCCATCATTAGCTCAAACGGCTATATTGTCACGAACGCCCATGTCGTTGAGTATTCGAAGGCAGAAGAAAA
AGACATCGCCCATGCGGCCTTTGAACAATTAGTAGCTGGAGTGGCCGAATATTTTGGCGTCGATTTTGACATCGCTTATG
ATTATATGATTGAGTATACGTTGTATACAAACGTCACCCGCGGTCTGAAAGTGATTTTACCTGGAGGGGATGTGCTTGAC
GGGGAAGTAAAAAGCTACGGGGCCCCAGTCAATCAAGGGAAAGACGTTGCGGTTTTAAAAGTCGAAGGGAAACATTTGCC
GACGCTGCCGCTTGGCGATTCGGACAACGTCCAAAATCAAGATGACATTTGGGTGATCGGCTACCCCGCCGCTGCTGAAT
CCGACTACCTTTCTCCCGACTCCTCCTTAGTCTCTTCCATGAACGCCGGCCCTGTTTCCGCCACTTCGAAAAAGACAGAA
CAAGGGAGTCCGGTCATCCAGATTGACGCCGCCGCCACCCATGGCAACAGCGGAGGACCCGTCATTAACAAACGCGGGGA
AATGATCGGCTTGCTCACCTTCCGCGGCGGCACTGTCAACCGCCAAGAAGTGCAAAGATTCAATTTTGTCGTTCCGGTCA
ATACCGTGAAAGAGTTTGTCAAGCAGGCTGGAGCCGACCAAGGGCAAGGAAGCATTGATACCCTCTTCCGCGAAGGATTG
ACGCTGTATTGGGGCGGTTATTATAAGGATGCCTTGGCCAAATTCGAAGCGGTCGAACGCCTCTATCCCGGCCATTCGGA
AATTAAACGGTTCATTACCGACAGCCAGCAAAAAAGCGGGCAAAGCAAAATTCTTTGGTCAACCTACAAAACCGCCTTCC
TTATTTTCGATGGCGTCGCTCTGCTTCTCATCATCGGACTGCTTGTGTTCACCTTCGCCTGTAAGCCAAAACAGCAAACC
AAGGCGGCTTCAGCCGACGGCCCACCGGTAGCCTCCGCCGATCTGAACGGTGACGGCAAAGTCCATCTCCAAGACGTGCT
GTTGGCCTTGCAACAACAGCAACAACAAACCGACGACAGCAAGAAAAAGGAGAGCCCATAG

Upstream 100 bases:

>100_bases
TTTTTCGGTGGTGCTCCAAAAGACGGATGGCGAATATAATATACCATTGTTGTTTTTAAATTTTCTGACAAATGAGCTGA
AACATGTGCGCAAACGAGCG

Downstream 100 bases:

>100_bases
CGACACCTTGCCATAAATATTATGATAAAAATGGGACATTTATGACTATACCCTCGCAAGGACAACATAGAGAATGTCCG
AACGTCCTTTTCTTTCAACA

Product: periplasmic serine proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MITLPISIIFAVCIAASFFLMNIKPDTSHVSQAQKLAEYTKPAVVRIVDYAIVEWKFVNNDPDVDAYLHQLDYRTMIGAS
GSGAIISSNGYIVTNAHVVEYSKAEEKDIAHAAFEQLVAGVAEYFGVDFDIAYDYMIEYTLYTNVTRGLKVILPGGDVLD
GEVKSYGAPVNQGKDVAVLKVEGKHLPTLPLGDSDNVQNQDDIWVIGYPAAAESDYLSPDSSLVSSMNAGPVSATSKKTE
QGSPVIQIDAAATHGNSGGPVINKRGEMIGLLTFRGGTVNRQEVQRFNFVVPVNTVKEFVKQAGADQGQGSIDTLFREGL
TLYWGGYYKDALAKFEAVERLYPGHSEIKRFITDSQQKSGQSKILWSTYKTAFLIFDGVALLLIIGLLVFTFACKPKQQT
KAASADGPPVASADLNGDGKVHLQDVLLALQQQQQQTDDSKKKESP

Sequences:

>Translated_446_residues
MITLPISIIFAVCIAASFFLMNIKPDTSHVSQAQKLAEYTKPAVVRIVDYAIVEWKFVNNDPDVDAYLHQLDYRTMIGAS
GSGAIISSNGYIVTNAHVVEYSKAEEKDIAHAAFEQLVAGVAEYFGVDFDIAYDYMIEYTLYTNVTRGLKVILPGGDVLD
GEVKSYGAPVNQGKDVAVLKVEGKHLPTLPLGDSDNVQNQDDIWVIGYPAAAESDYLSPDSSLVSSMNAGPVSATSKKTE
QGSPVIQIDAAATHGNSGGPVINKRGEMIGLLTFRGGTVNRQEVQRFNFVVPVNTVKEFVKQAGADQGQGSIDTLFREGL
TLYWGGYYKDALAKFEAVERLYPGHSEIKRFITDSQQKSGQSKILWSTYKTAFLIFDGVALLLIIGLLVFTFACKPKQQT
KAASADGPPVASADLNGDGKVHLQDVLLALQQQQQQTDDSKKKESP
>Mature_446_residues
MITLPISIIFAVCIAASFFLMNIKPDTSHVSQAQKLAEYTKPAVVRIVDYAIVEWKFVNNDPDVDAYLHQLDYRTMIGAS
GSGAIISSNGYIVTNAHVVEYSKAEEKDIAHAAFEQLVAGVAEYFGVDFDIAYDYMIEYTLYTNVTRGLKVILPGGDVLD
GEVKSYGAPVNQGKDVAVLKVEGKHLPTLPLGDSDNVQNQDDIWVIGYPAAAESDYLSPDSSLVSSMNAGPVSATSKKTE
QGSPVIQIDAAATHGNSGGPVINKRGEMIGLLTFRGGTVNRQEVQRFNFVVPVNTVKEFVKQAGADQGQGSIDTLFREGL
TLYWGGYYKDALAKFEAVERLYPGHSEIKRFITDSQQKSGQSKILWSTYKTAFLIFDGVALLLIIGLLVFTFACKPKQQT
KAASADGPPVASADLNGDGKVHLQDVLLALQQQQQQTDDSKKKESP

Specific function: A putative protease, its function overlaps that of the related putative proteases HhoA and HhoB [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential). Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 48462; Mature: 48462

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLPISIIFAVCIAASFFLMNIKPDTSHVSQAQKLAEYTKPAVVRIVDYAIVEWKFVNN
CEEEHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCHHHHHEEEEEEEEEEECC
DPDVDAYLHQLDYRTMIGASGSGAIISSNGYIVTNAHVVEYSKAEEKDIAHAAFEQLVAG
CCCHHHHHHHHHHHHEECCCCCCCEEECCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
VAEYFGVDFDIAYDYMIEYTLYTNVTRGLKVILPGGDVLDGEVKSYGAPVNQGKDVAVLK
HHHHHCCCEEEEEEEEEEEEEECCCCCCEEEEECCCCEECCCHHHCCCCCCCCCCEEEEE
VEGKHLPTLPLGDSDNVQNQDDIWVIGYPAAAESDYLSPDSSLVSSMNAGPVSATSKKTE
ECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
QGSPVIQIDAAATHGNSGGPVINKRGEMIGLLTFRGGTVNRQEVQRFNFVVPVNTVKEFV
CCCCEEEEEEEECCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHCEEEEHHHHHHHH
KQAGADQGQGSIDTLFREGLTLYWGGYYKDALAKFEAVERLYPGHSEIKRFITDSQQKSG
HHCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCC
QSKILWSTYKTAFLIFDGVALLLIIGLLVFTFACKPKQQTKAASADGPPVASADLNGDGK
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCC
VHLQDVLLALQQQQQQTDDSKKKESP
EEHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MITLPISIIFAVCIAASFFLMNIKPDTSHVSQAQKLAEYTKPAVVRIVDYAIVEWKFVNN
CEEEHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCHHHHHEEEEEEEEEEECC
DPDVDAYLHQLDYRTMIGASGSGAIISSNGYIVTNAHVVEYSKAEEKDIAHAAFEQLVAG
CCCHHHHHHHHHHHHEECCCCCCCEEECCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
VAEYFGVDFDIAYDYMIEYTLYTNVTRGLKVILPGGDVLDGEVKSYGAPVNQGKDVAVLK
HHHHHCCCEEEEEEEEEEEEEECCCCCCEEEEECCCCEECCCHHHCCCCCCCCCCEEEEE
VEGKHLPTLPLGDSDNVQNQDDIWVIGYPAAAESDYLSPDSSLVSSMNAGPVSATSKKTE
ECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
QGSPVIQIDAAATHGNSGGPVINKRGEMIGLLTFRGGTVNRQEVQRFNFVVPVNTVKEFV
CCCCEEEEEEEECCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHCEEEEHHHHHHHH
KQAGADQGQGSIDTLFREGLTLYWGGYYKDALAKFEAVERLYPGHSEIKRFITDSQQKSG
HHCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCC
QSKILWSTYKTAFLIFDGVALLLIIGLLVFTFACKPKQQTKAASADGPPVASADLNGDGK
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCC
VHLQDVLLALQQQQQQTDDSKKKESP
EEHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]