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The map label for this gene is ytkD [H]

Identifier: 138896394

GI number: 138896394

Start: 2875411

End: 2876004

Strand: Reverse

Name: ytkD [H]

Synonym: GTNG_2757

Alternate gene names: 138896394

Gene position: 2876004-2875411 (Counterclockwise)

Preceding gene: 138896395

Following gene: 138896390

Centisome position: 81.01

GC content: 55.56

Gene sequence:

>594_bases
ATGACGAAACGAAGGCGCAGATCCGATCGCTTGGCATCCTTCCTGATGACAGAGAAACAAACGAGTAAAAAGCCGCGAAT
GGGGCGGCTTTTTTTGTATAATGGGGAGAGGAAAGGAGCGAGTCCGATGTATGAGTTTCGCGATTATTACGGGCATCGCG
TCCGGCTGGCGTTTGCGGATCATCCGTTTTCCTTGACGCCTGGGCATGTGTGGGTCATTTGCCGCTATCAAGGTCAGTGG
TTGTTGACGGATCACCCGCGCCGCGGTCTCGAATTTCCCGGCGGCAAAGTTGAAGACGGGGAAACGGCCGAAGAAGCTGC
CGCTCGCGAGGTCATGGAAGAAACCGGCGGGGTGGTTGGCCGTCTTTCCTATGTCGGCCAATATGAGGTGGAGCCGGATA
TTGTGAAAAACATTTATTTCGCCGACATTGCGGCGCTTTCCGAGCGGGACTCCTATTGGGAGACGAACGGCCCCGTGCTG
CTTTCGGCACTGCCGGATCATATCCGCACGGATGCGCGCTTTAGTTATCTCATGAAAGACGATGTGCTTCCGTTGGCGTT
GGCGGAAGTCAAACAGCGCGGGTGGATCGGCTAA

Upstream 100 bases:

>100_bases
CGCGCCCATGTGCCATATGTCCAATATCATTACGATCGGGAAAACGATGCGTATGACGAGACGATGATGAAAATTTACGA
AATGATTTATCGGCTTGGCA

Downstream 100 bases:

>100_bases
TATTCGGCGGCAAAACGAAAAGAGACGTTCATCGATCGTTCACGAACGTCTCTTAGCGGCGGTTGCTCCATTTCTTTTCG
ATCATAGCGACAAGTTGATA

Product: MutT/nudix family protein

Products: NA

Alternate protein names: 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTKRRRRSDRLASFLMTEKQTSKKPRMGRLFLYNGERKGASPMYEFRDYYGHRVRLAFADHPFSLTPGHVWVICRYQGQW
LLTDHPRRGLEFPGGKVEDGETAEEAAAREVMEETGGVVGRLSYVGQYEVEPDIVKNIYFADIAALSERDSYWETNGPVL
LSALPDHIRTDARFSYLMKDDVLPLALAEVKQRGWIG

Sequences:

>Translated_197_residues
MTKRRRRSDRLASFLMTEKQTSKKPRMGRLFLYNGERKGASPMYEFRDYYGHRVRLAFADHPFSLTPGHVWVICRYQGQW
LLTDHPRRGLEFPGGKVEDGETAEEAAAREVMEETGGVVGRLSYVGQYEVEPDIVKNIYFADIAALSERDSYWETNGPVL
LSALPDHIRTDARFSYLMKDDVLPLALAEVKQRGWIG
>Mature_196_residues
TKRRRRSDRLASFLMTEKQTSKKPRMGRLFLYNGERKGASPMYEFRDYYGHRVRLAFADHPFSLTPGHVWVICRYQGQWL
LTDHPRRGLEFPGGKVEDGETAEEAAAREVMEETGGVVGRLSYVGQYEVEPDIVKNIYFADIAALSERDSYWETNGPVLL
SALPDHIRTDARFSYLMKDDVLPLALAEVKQRGWIG

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal effici

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014078 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22648; Mature: 22517

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRRRRSDRLASFLMTEKQTSKKPRMGRLFLYNGERKGASPMYEFRDYYGHRVRLAFAD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCEEEEEECC
HPFSLTPGHVWVICRYQGQWLLTDHPRRGLEFPGGKVEDGETAEEAAAREVMEETGGVVG
CCCEECCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEE
RLSYVGQYEVEPDIVKNIYFADIAALSERDSYWETNGPVLLSALPDHIRTDARFSYLMKD
EHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHCCHHHHHHHHC
DVLPLALAEVKQRGWIG
CCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKRRRRSDRLASFLMTEKQTSKKPRMGRLFLYNGERKGASPMYEFRDYYGHRVRLAFAD
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCEEEEEECC
HPFSLTPGHVWVICRYQGQWLLTDHPRRGLEFPGGKVEDGETAEEAAAREVMEETGGVVG
CCCEECCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEE
RLSYVGQYEVEPDIVKNIYFADIAALSERDSYWETNGPVLLSALPDHIRTDARFSYLMKD
EHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHCCHHHHHHHHC
DVLPLALAEVKQRGWIG
CCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]