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The map label for this gene is acuC [H]

Identifier: 138896351

GI number: 138896351

Start: 2830063

End: 2831232

Strand: Direct

Name: acuC [H]

Synonym: GTNG_2714

Alternate gene names: 138896351

Gene position: 2830063-2831232 (Clockwise)

Preceding gene: 138896350

Following gene: 138896363

Centisome position: 79.71

GC content: 56.32

Gene sequence:

>1170_bases
ATGAGCGACAAGTGCGTATTTGTTTATAGCGAACAATTTCTCCGTTATAAGTTTCATGATGACCACCCGTTTAACCAGCT
GCGGGTCAAGCTGACCTACGATTTATTGCGAACCATCGGCGCGTTGGACGACCGTCACGTCGTCCCTCCGCGCATGGCGA
CGGATGAGGAGCTGACCCTCATCCACGATCGGGCATACATCGAAGCGGTCAAGGCAGCCGGGCGCGGCGAGCTTTCGGAA
ACCGCCGCGGCAAACTACGGCCTCGGCACCGAAGACACGCCGATATTTCCGAACATGCATGAGGCGAGCGCCCTCCTTGT
TGGCAGCACGCTGACGGCTGTGGATTACGTCTTATCTGGACAGGCCGACCATGCGCTCAACCTTGGCGGCGGCTTACATC
ATGGATTCCGTGGCAAGGCGTCGGGCTTTTGCGTCTACAATGACAGCGCGGTCGCCATTCAATACATTCGCGAAAAATAC
GGATTGCGCGTCTTGTATGTCGACACCGACGCCCACCATGGCGATGGGGTGCAATGGGCGTTTTATGACGATCCAAACGT
CTGCACGTTCTCCATTCATGAGACAGGCCGCTACTTGTTTCCGGGGACAGGAAACGTCAATGAACGTGGCCATGGAGCGG
GTTACGGCTATTCGTTCAACATTCCGGTCGACGCCTTTACAGAAGACGAGTCATGGCTTTATGCCTACACGATGGCACTC
CGGGAAATCGCTGACTTTTTCCGCCCCGATGTCATCGTGACGCAAAATGGGGTGGATGCCCATTATTACGATCCGCTTAC
CCATTTGTCGGTAACGATGAAAACGTATCGCGCCATTCCGAAGCTCGCCCACCAAATCGCCCATGAATATTGCGGCGGGC
GCTGGATCGCCGTCGGCGGCGGTGGCTACGACATTTGGCGCGTTGTCCCACGGGCATGGGCGCTTCTTTGGTTAGAAATG
ACGGAACAATCCGATATTTCTGGCCCTCTGCCGGCCGCTTGGCGCGAGCGATGGCAGCCACTTTCCCCGGTCTCCTTGCC
GCTCGAATGGGACGATCCGGACAATTTGTATGCACCGATCCCACGCAAAGCGGAAATTAGCGAAAAAAATGCCCAGACGG
TGGAAAAAGCGTTGTATTTCATCCGCAGCCAGCGGCGCGCGGGCACTTGA

Upstream 100 bases:

>100_bases
TAGTGTTTCGCGTGCAAACGATGAACCCGATCAACTTAATCCATGATTTGAAAAAGGCTGGTTATACGGTGTTATGGCCG
AACTTGCCGGGGGTTACATC

Downstream 100 bases:

>100_bases
TCCTTACTTCCTGCTACAGACGTGCGGGGATTCGCGGTTTCCATTGGCCAAACAAGAGGCGGTGCAGAGAAAGCACCTCC
TCTTATTTTGCTTCAAGAAG

Product: acetoin utilization protein AcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSDKCVFVYSEQFLRYKFHDDHPFNQLRVKLTYDLLRTIGALDDRHVVPPRMATDEELTLIHDRAYIEAVKAAGRGELSE
TAAANYGLGTEDTPIFPNMHEASALLVGSTLTAVDYVLSGQADHALNLGGGLHHGFRGKASGFCVYNDSAVAIQYIREKY
GLRVLYVDTDAHHGDGVQWAFYDDPNVCTFSIHETGRYLFPGTGNVNERGHGAGYGYSFNIPVDAFTEDESWLYAYTMAL
REIADFFRPDVIVTQNGVDAHYYDPLTHLSVTMKTYRAIPKLAHQIAHEYCGGRWIAVGGGGYDIWRVVPRAWALLWLEM
TEQSDISGPLPAAWRERWQPLSPVSLPLEWDDPDNLYAPIPRKAEISEKNAQTVEKALYFIRSQRRAGT

Sequences:

>Translated_389_residues
MSDKCVFVYSEQFLRYKFHDDHPFNQLRVKLTYDLLRTIGALDDRHVVPPRMATDEELTLIHDRAYIEAVKAAGRGELSE
TAAANYGLGTEDTPIFPNMHEASALLVGSTLTAVDYVLSGQADHALNLGGGLHHGFRGKASGFCVYNDSAVAIQYIREKY
GLRVLYVDTDAHHGDGVQWAFYDDPNVCTFSIHETGRYLFPGTGNVNERGHGAGYGYSFNIPVDAFTEDESWLYAYTMAL
REIADFFRPDVIVTQNGVDAHYYDPLTHLSVTMKTYRAIPKLAHQIAHEYCGGRWIAVGGGGYDIWRVVPRAWALLWLEM
TEQSDISGPLPAAWRERWQPLSPVSLPLEWDDPDNLYAPIPRKAEISEKNAQTVEKALYFIRSQRRAGT
>Mature_388_residues
SDKCVFVYSEQFLRYKFHDDHPFNQLRVKLTYDLLRTIGALDDRHVVPPRMATDEELTLIHDRAYIEAVKAAGRGELSET
AAANYGLGTEDTPIFPNMHEASALLVGSTLTAVDYVLSGQADHALNLGGGLHHGFRGKASGFCVYNDSAVAIQYIREKYG
LRVLYVDTDAHHGDGVQWAFYDDPNVCTFSIHETGRYLFPGTGNVNERGHGAGYGYSFNIPVDAFTEDESWLYAYTMALR
EIADFFRPDVIVTQNGVDAHYYDPLTHLSVTMKTYRAIPKLAHQIAHEYCGGRWIAVGGGGYDIWRVVPRAWALLWLEMT
EQSDISGPLPAAWRERWQPLSPVSLPLEWDDPDNLYAPIPRKAEISEKNAQTVEKALYFIRSQRRAGT

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=313, Percent_Identity=32.9073482428115, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI13128862, Length=350, Percent_Identity=31.1428571428571, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI293336691, Length=273, Percent_Identity=34.0659340659341, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI8923769, Length=314, Percent_Identity=31.8471337579618, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI262073092, Length=228, Percent_Identity=33.7719298245614, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI20070354, Length=343, Percent_Identity=31.1953352769679, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI30795202, Length=315, Percent_Identity=28.8888888888889, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI17158039, Length=314, Percent_Identity=28.343949044586, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI30795204, Length=315, Percent_Identity=28.8888888888889, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI13128864, Length=316, Percent_Identity=31.3291139240506, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI262073088, Length=197, Percent_Identity=36.5482233502538, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI153085395, Length=356, Percent_Identity=27.247191011236, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226529806, Length=233, Percent_Identity=35.1931330472103, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI62750347, Length=316, Percent_Identity=29.1139240506329, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI62750349, Length=316, Percent_Identity=29.1139240506329, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI169234807, Length=186, Percent_Identity=31.7204301075269, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI148539870, Length=186, Percent_Identity=31.7204301075269, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI217272877, Length=261, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI209862883, Length=253, Percent_Identity=24.5059288537549, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17508561, Length=330, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17561978, Length=313, Percent_Identity=31.629392971246, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17534739, Length=297, Percent_Identity=30.3030303030303, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17540332, Length=312, Percent_Identity=30.7692307692308, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193206283, Length=312, Percent_Identity=30.7692307692308, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17540334, Length=312, Percent_Identity=30.7692307692308, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193209491, Length=201, Percent_Identity=29.3532338308458, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25154020, Length=306, Percent_Identity=24.1830065359477, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25154022, Length=312, Percent_Identity=24.6794871794872, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193207430, Length=289, Percent_Identity=26.2975778546713, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17537347, Length=254, Percent_Identity=25.1968503937008, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321244, Length=319, Percent_Identity=31.0344827586207, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323999, Length=314, Percent_Identity=28.9808917197452, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324307, Length=347, Percent_Identity=27.6657060518732, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325325, Length=213, Percent_Identity=28.6384976525822, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644244, Length=340, Percent_Identity=31.7647058823529, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24657891, Length=313, Percent_Identity=31.629392971246, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642144, Length=340, Percent_Identity=30.5882352941176, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24642142, Length=340, Percent_Identity=30.5882352941176, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24642146, Length=340, Percent_Identity=30.5882352941176, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281360899, Length=340, Percent_Identity=30.5882352941176, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281360801, Length=312, Percent_Identity=28.8461538461538, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641720, Length=312, Percent_Identity=28.8461538461538, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281360799, Length=312, Percent_Identity=28.8461538461538, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24649807, Length=258, Percent_Identity=28.2945736434109, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 43772; Mature: 43640

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKCVFVYSEQFLRYKFHDDHPFNQLRVKLTYDLLRTIGALDDRHVVPPRMATDEELTL
CCCCEEEEEECCEEEEEECCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
IHDRAYIEAVKAAGRGELSETAAANYGLGTEDTPIFPNMHEASALLVGSTLTAVDYVLSG
EEHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCEEEECCHHHHHHHHHCC
QADHALNLGGGLHHGFRGKASGFCVYNDSAVAIQYIREKYGLRVLYVDTDAHHGDGVQWA
CCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEEE
FYDDPNVCTFSIHETGRYLFPGTGNVNERGHGAGYGYSFNIPVDAFTEDESWLYAYTMAL
EECCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCEEEECCCCEECCCCCCHHHHHHHH
REIADFFRPDVIVTQNGVDAHYYDPLTHLSVTMKTYRAIPKLAHQIAHEYCGGRWIAVGG
HHHHHHHCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GGYDIWRVVPRAWALLWLEMTEQSDISGPLPAAWRERWQPLSPVSLPLEWDDPDNLYAPI
CCHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCC
PRKAEISEKNAQTVEKALYFIRSQRRAGT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDKCVFVYSEQFLRYKFHDDHPFNQLRVKLTYDLLRTIGALDDRHVVPPRMATDEELTL
CCCEEEEEECCEEEEEECCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
IHDRAYIEAVKAAGRGELSETAAANYGLGTEDTPIFPNMHEASALLVGSTLTAVDYVLSG
EEHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCEEEECCHHHHHHHHHCC
QADHALNLGGGLHHGFRGKASGFCVYNDSAVAIQYIREKYGLRVLYVDTDAHHGDGVQWA
CCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEEE
FYDDPNVCTFSIHETGRYLFPGTGNVNERGHGAGYGYSFNIPVDAFTEDESWLYAYTMAL
EECCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCEEEECCCCEECCCCCCHHHHHHHH
REIADFFRPDVIVTQNGVDAHYYDPLTHLSVTMKTYRAIPKLAHQIAHEYCGGRWIAVGG
HHHHHHHCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GGYDIWRVVPRAWALLWLEMTEQSDISGPLPAAWRERWQPLSPVSLPLEWDDPDNLYAPI
CCHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCC
PRKAEISEKNAQTVEKALYFIRSQRRAGT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]