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The map label for this gene is moaB [H]

Identifier: 138896324

GI number: 138896324

Start: 2796603

End: 2797163

Strand: Reverse

Name: moaB [H]

Synonym: GTNG_2687

Alternate gene names: 138896324

Gene position: 2797163-2796603 (Counterclockwise)

Preceding gene: 138896325

Following gene: 138896322

Centisome position: 78.79

GC content: 56.15

Gene sequence:

>561_bases
TTGCTATACTTATGGATGAAGACGATAAGCGAAAAGGAGAGACGAACGATGAGCACGATCGAACATAAACAAGAAGCTCC
GAAAACCGTCCGCTGCAAAGTCGTGACGATCAGCGATACGAGAACGGAAGAAACCGACCGGAGCGGCCGGCTGATGATCG
AGTTGCTGACCGAGGCGGGGCATGACGTTGTTGGCTATGACATTGTGAAAGATGAGGAAGCCGCCATTCGCGAGGCGGTG
CTCGACGGCTGCCGTCGCACTGATGTCGACGCAGTGCTCACAAACGGCGGCACTGGCATCGCCAAGCGTGATGTGACGAT
CGAAACGGTGAGTGCGCTGCTCGAGAAGGAGATCGTCGGCTTTGGCGAATTGTTCCGCTTTTTAAGTTATACGGAAGACA
TTGGCTCGGCGGCGATGCTGTCGCGCGCCATCGCCGGTGTGGCGATGGATACCGCCATCTTTTGCACTCCTGGCTCAACC
GGAGCGGTGCGCCTTGCGATGACGAAGCTCATCTTGCCGGAACTCGGGCATGTCATGAGGGAGATTCGAAAAGACCGGTA
A

Upstream 100 bases:

>100_bases
GCGGGATAGCGCAAAATAAAATGAAGCGGTTCTCTCCTAGCTTCTAGGAGGGAGCCGCTTTTTCGTTGGTCGCAGCGTTT
GGCAGGATACCTGCTGTTTT

Downstream 100 bases:

>100_bases
AGGAAAACGTGTCCGTTCGGTAAGAACGGACACGAAGTTTGATCACACGTTTTTCTGTTTTTCCCTTTCTTGATTGCGAA
GGATAAACCGCTGGATTTTT

Product: molybdopterin biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MLYLWMKTISEKERRTMSTIEHKQEAPKTVRCKVVTISDTRTEETDRSGRLMIELLTEAGHDVVGYDIVKDEEAAIREAV
LDGCRRTDVDAVLTNGGTGIAKRDVTIETVSALLEKEIVGFGELFRFLSYTEDIGSAAMLSRAIAGVAMDTAIFCTPGST
GAVRLAMTKLILPELGHVMREIRKDR

Sequences:

>Translated_186_residues
MLYLWMKTISEKERRTMSTIEHKQEAPKTVRCKVVTISDTRTEETDRSGRLMIELLTEAGHDVVGYDIVKDEEAAIREAV
LDGCRRTDVDAVLTNGGTGIAKRDVTIETVSALLEKEIVGFGELFRFLSYTEDIGSAAMLSRAIAGVAMDTAIFCTPGST
GAVRLAMTKLILPELGHVMREIRKDR
>Mature_186_residues
MLYLWMKTISEKERRTMSTIEHKQEAPKTVRCKVVTISDTRTEETDRSGRLMIELLTEAGHDVVGYDIVKDEEAAIREAV
LDGCRRTDVDAVLTNGGTGIAKRDVTIETVSALLEKEIVGFGELFRFLSYTEDIGSAAMLSRAIAGVAMDTAIFCTPGST
GAVRLAMTKLILPELGHVMREIRKDR

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=159, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI10880983, Length=159, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1787000, Length=145, Percent_Identity=44.8275862068966, Blast_Score=117, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136978, Length=152, Percent_Identity=36.1842105263158, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24638841, Length=152, Percent_Identity=36.1842105263158, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 20595; Mature: 20595

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLWMKTISEKERRTMSTIEHKQEAPKTVRCKVVTISDTRTEETDRSGRLMIELLTEAG
CEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCC
HDVVGYDIVKDEEAAIREAVLDGCRRTDVDAVLTNGGTGIAKRDVTIETVSALLEKEIVG
CCEECCEEECCHHHHHHHHHHHHHCCCCHHHEEECCCCCCEECCCHHHHHHHHHHHHHHC
FGELFRFLSYTEDIGSAAMLSRAIAGVAMDTAIFCTPGSTGAVRLAMTKLILPELGHVMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
EIRKDR
HHHHCC
>Mature Secondary Structure
MLYLWMKTISEKERRTMSTIEHKQEAPKTVRCKVVTISDTRTEETDRSGRLMIELLTEAG
CEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCC
HDVVGYDIVKDEEAAIREAVLDGCRRTDVDAVLTNGGTGIAKRDVTIETVSALLEKEIVG
CCEECCEEECCHHHHHHHHHHHHHCCCCHHHEEECCCCCCEECCCHHHHHHHHHHHHHHC
FGELFRFLSYTEDIGSAAMLSRAIAGVAMDTAIFCTPGSTGAVRLAMTKLILPELGHVMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
EIRKDR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]