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The map label for this gene is ykvY [H]

Identifier: 138896313

GI number: 138896313

Start: 2786320

End: 2787414

Strand: Direct

Name: ykvY [H]

Synonym: GTNG_2676

Alternate gene names: 138896313

Gene position: 2786320-2787414 (Clockwise)

Preceding gene: 138896309

Following gene: 138896317

Centisome position: 78.48

GC content: 56.89

Gene sequence:

>1095_bases
ATGAATCAACGGCTGAAATCGTTATCATTATGGCTTCAACATCATGATGATTCATTTGCCTTCATCACGTCAAGCGCCAA
CGTCTTTTATTTAAGCGGATTTTGGTGTGACCCGCACGAGCGGCTGCTCGCGCTTCTCGTTTTTCCTGACGGCGAGCCCG
TGCTCGTCTGCCCGCAAATGGAAATCGCCCGCGCCCGCCGGGCTGGTTGGGGGTATGCGGTGATCGGCTATGATGACAGC
ACCGACCCGTGGGAAGAAATTCACCGCCATCTGCAAGGACGAGCGATTACAGCAAACACCATCGCCGTCGAGAAAAGCCA
TTTGTCATTTGCGCGTTTCGAGCAGCTTTCGGCGCTGTTTCCCAACGTCCAATGGCTCGACGCTGAAGAAACACTGCGTC
AGCTTCGCCTTATCAAAGACGAGCAAGAAATGAAACGGTTGCGCCAGGCAGCCGAACTCGCCGACCGGGCGATTGAAATC
GGCGTATCGGCCATCCGCCCCGGCGTAACAGAGCTCGAGCTCGTCGCTGTGATCGAATATGAACTGAAAAAGCTCGGCGT
GGAAGGAATGTCGTTCCCGACAACCGTGCTGACAGGCGCGCGCACGGCCGATCCGCACGGCGTGCCGGGATCGGCAGCGG
TCGCTTCGGGCGATTTCATCTTATTCGATTTGGGAGTCATCGTTGACGGCTATTGTTCGGACATCACCCGCACTGTCGTC
TGTCAAACGGCAAGCGACGAACAACGACTCATTTACGACACCGTCCTGCGCGCCCAACAAGCGGCGATTGATGCTTGCCA
CCCGCAAACAGCTTTGGGCGCCATCGATCGCGCCGCCCGCAGCGTCATCGAACAGGCCGGCTATGGTCCGTACTTCACCC
ATCGCGTCGGCCACGGCTTAGGGATTGAGGTCCACGAACACCCATCCCTCCATGGCGCAAACGAAGAGCTTCTTGTCCCA
GGGATGGTGTTTACGATCGAACCAGGCATTTACGTCCCCGCAATCGGCGGCGTGCGCATTGAGGATGACATCGCTGTCAC
CGACAGCGGGGGTGAGGTGCTGACATCGTTTTCAAAAGAACTGATCATCGTTTAA

Upstream 100 bases:

>100_bases
GCGCGTTCATTTCCTTCTTTTCCCGCTTATCCATTTACAATTTGCCCGTTTCTTGGTACGCTCAAAATGAACGATAGCGA
AAAAAGGAAGGAATGGAACG

Downstream 100 bases:

>100_bases
CGTGCGGAGTTTAGAAACTGATTCTCTTGTCTAAACAGCGAAAGCTGCCCGCCGGCCTGCTGCAAGGCCGAGTTGGGCAG
CTTTGCGGTTTATTGGCTTT

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MNQRLKSLSLWLQHHDDSFAFITSSANVFYLSGFWCDPHERLLALLVFPDGEPVLVCPQMEIARARRAGWGYAVIGYDDS
TDPWEEIHRHLQGRAITANTIAVEKSHLSFARFEQLSALFPNVQWLDAEETLRQLRLIKDEQEMKRLRQAAELADRAIEI
GVSAIRPGVTELELVAVIEYELKKLGVEGMSFPTTVLTGARTADPHGVPGSAAVASGDFILFDLGVIVDGYCSDITRTVV
CQTASDEQRLIYDTVLRAQQAAIDACHPQTALGAIDRAARSVIEQAGYGPYFTHRVGHGLGIEVHEHPSLHGANEELLVP
GMVFTIEPGIYVPAIGGVRIEDDIAVTDSGGEVLTSFSKELIIV

Sequences:

>Translated_364_residues
MNQRLKSLSLWLQHHDDSFAFITSSANVFYLSGFWCDPHERLLALLVFPDGEPVLVCPQMEIARARRAGWGYAVIGYDDS
TDPWEEIHRHLQGRAITANTIAVEKSHLSFARFEQLSALFPNVQWLDAEETLRQLRLIKDEQEMKRLRQAAELADRAIEI
GVSAIRPGVTELELVAVIEYELKKLGVEGMSFPTTVLTGARTADPHGVPGSAAVASGDFILFDLGVIVDGYCSDITRTVV
CQTASDEQRLIYDTVLRAQQAAIDACHPQTALGAIDRAARSVIEQAGYGPYFTHRVGHGLGIEVHEHPSLHGANEELLVP
GMVFTIEPGIYVPAIGGVRIEDDIAVTDSGGEVLTSFSKELIIV
>Mature_364_residues
MNQRLKSLSLWLQHHDDSFAFITSSANVFYLSGFWCDPHERLLALLVFPDGEPVLVCPQMEIARARRAGWGYAVIGYDDS
TDPWEEIHRHLQGRAITANTIAVEKSHLSFARFEQLSALFPNVQWLDAEETLRQLRLIKDEQEMKRLRQAAELADRAIEI
GVSAIRPGVTELELVAVIEYELKKLGVEGMSFPTTVLTGARTADPHGVPGSAAVASGDFILFDLGVIVDGYCSDITRTVV
CQTASDEQRLIYDTVLRAQQAAIDACHPQTALGAIDRAARSVIEQAGYGPYFTHRVGHGLGIEVHEHPSLHGANEELLVP
GMVFTIEPGIYVPAIGGVRIEDDIAVTDSGGEVLTSFSKELIIV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=257, Percent_Identity=32.295719844358, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI149589008, Length=312, Percent_Identity=28.2051282051282, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI260593665, Length=312, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40385867, Length=205, Percent_Identity=29.7560975609756, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI260593663, Length=274, Percent_Identity=27.3722627737226, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI164420681, Length=264, Percent_Identity=25, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788728, Length=234, Percent_Identity=44.017094017094, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789275, Length=295, Percent_Identity=29.8305084745763, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=26.2096774193548, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71989583, Length=256, Percent_Identity=27.34375, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508215, Length=305, Percent_Identity=24.9180327868852, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=26.8774703557312, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323273, Length=247, Percent_Identity=26.7206477732794, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321118, Length=288, Percent_Identity=24.6527777777778, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19920384, Length=313, Percent_Identity=29.073482428115, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21357079, Length=285, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355531, Length=246, Percent_Identity=24.390243902439, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39984; Mature: 39984

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRLKSLSLWLQHHDDSFAFITSSANVFYLSGFWCDPHERLLALLVFPDGEPVLVCPQM
CCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEECHHHHEEEEEEECCCCCEEEECCH
EIARARRAGWGYAVIGYDDSTDPWEEIHRHLQGRAITANTIAVEKSHLSFARFEQLSALF
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHC
PNVQWLDAEETLRQLRLIKDEQEMKRLRQAAELADRAIEIGVSAIRPGVTELELVAVIEY
CCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
ELKKLGVEGMSFPTTVLTGARTADPHGVPGSAAVASGDFILFDLGVIVDGYCSDITRTVV
HHHHCCCCCCCCCHHHEECCCCCCCCCCCCCCEEECCCEEEEEHHHHHHHHHHHHEEEEE
CQTASDEQRLIYDTVLRAQQAAIDACHPQTALGAIDRAARSVIEQAGYGPYFTHRVGHGL
EECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
GIEVHEHPSLHGANEELLVPGMVFTIEPGIYVPAIGGVRIEDDIAVTDSGGEVLTSFSKE
CEEEECCCCCCCCCCCEEECEEEEEECCCEEEECCCCEEEECCEEEECCCCHHHHHCCCC
LIIV
EEEC
>Mature Secondary Structure
MNQRLKSLSLWLQHHDDSFAFITSSANVFYLSGFWCDPHERLLALLVFPDGEPVLVCPQM
CCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEECHHHHEEEEEEECCCCCEEEECCH
EIARARRAGWGYAVIGYDDSTDPWEEIHRHLQGRAITANTIAVEKSHLSFARFEQLSALF
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHC
PNVQWLDAEETLRQLRLIKDEQEMKRLRQAAELADRAIEIGVSAIRPGVTELELVAVIEY
CCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
ELKKLGVEGMSFPTTVLTGARTADPHGVPGSAAVASGDFILFDLGVIVDGYCSDITRTVV
HHHHCCCCCCCCCHHHEECCCCCCCCCCCCCCEEECCCEEEEEHHHHHHHHHHHHEEEEE
CQTASDEQRLIYDTVLRAQQAAIDACHPQTALGAIDRAARSVIEQAGYGPYFTHRVGHGL
EECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
GIEVHEHPSLHGANEELLVPGMVFTIEPGIYVPAIGGVRIEDDIAVTDSGGEVLTSFSKE
CEEEECCCCCCCCCCCEEECEEEEEECCCEEEECCCCEEEECCEEEECCCCHHHHHCCCC
LIIV
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]