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The map label for this gene is uxuR [H]

Identifier: 138896304

GI number: 138896304

Start: 2776661

End: 2777308

Strand: Reverse

Name: uxuR [H]

Synonym: GTNG_2667

Alternate gene names: 138896304

Gene position: 2777308-2776661 (Counterclockwise)

Preceding gene: 138896305

Following gene: 138896303

Centisome position: 78.23

GC content: 54.94

Gene sequence:

>648_bases
TTGCTAGTAAATCGCCGGGAGGGATCTTCGTTGAACGACGAGAAAGTGTATGCTGAGACGTTGAAACATATTCACCGTCT
CATTGTTCAGGATGGCCTCGCCCCCGGCGATAAGCTGCCGTCGGAGCGGGAGTTGGCCGAACGGCTTGGAGTCGGTCGTT
CGTCAGTGCGCGAGGCGCTGCGGGCGCTCGAATTTCTCGGCCTGATTGAAACGCGGCGCGGCGAAGGAACCTATATGTGT
GAGATCGGCAGCCATCAGCTAGTCGATTTGCTGGCGATGTTTTTGCTTGAAAATGAACGGGCAAAAGCCGATTTGGCGGA
AACGAAATGGCTTGTCGAACGGCTGTTGCTTGAACTCTTCTGTCAGCGTCAAGGTGAGGAAGCCATAGGAAGGCTTGAAA
AAACCGTTCGTCAAAAACCGATCGATTTCGAGCGGTTTTTTCAGACGATCGCCGAAGCAGCTGGCAATTACTTGCTTGTC
CGCATTTGGCGGGCGTTGTCCGCGTTTGCGGCCGCCTTTGCGCCGAAGCCGTCGCTTGCGGATTCATTTTATGACCAGCT
GCTAGCAGCATTGAAAAAGCGTGATTCGGCGGAAGCCATCGCCGTATGGGAGGCGCACCGGCCCTGGCCATTGTCGAAAA
AGAGCTGA

Upstream 100 bases:

>100_bases
AGACCAGTATGGAATTGAGAAGTGAGGAAAAGCCGCCGATTCTCGTCACCCATCGTTCCCAAGGTCGGTAAAGATTCAGT
TTTCGACTTTAGAAATCTTT

Downstream 100 bases:

>100_bases
CACCGTTTGACAAACAATCGTACGTATTTTCGATAAAGTAGTAGAGAGGCGAAAACGCAAAGGAGGGGCTCCCTCGTGTG
GAAAGATTTATTTGTGAAAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLVNRREGSSLNDEKVYAETLKHIHRLIVQDGLAPGDKLPSERELAERLGVGRSSVREALRALEFLGLIETRRGEGTYMC
EIGSHQLVDLLAMFLLENERAKADLAETKWLVERLLLELFCQRQGEEAIGRLEKTVRQKPIDFERFFQTIAEAAGNYLLV
RIWRALSAFAAAFAPKPSLADSFYDQLLAALKKRDSAEAIAVWEAHRPWPLSKKS

Sequences:

>Translated_215_residues
MLVNRREGSSLNDEKVYAETLKHIHRLIVQDGLAPGDKLPSERELAERLGVGRSSVREALRALEFLGLIETRRGEGTYMC
EIGSHQLVDLLAMFLLENERAKADLAETKWLVERLLLELFCQRQGEEAIGRLEKTVRQKPIDFERFFQTIAEAAGNYLLV
RIWRALSAFAAAFAPKPSLADSFYDQLLAALKKRDSAEAIAVWEAHRPWPLSKKS
>Mature_215_residues
MLVNRREGSSLNDEKVYAETLKHIHRLIVQDGLAPGDKLPSERELAERLGVGRSSVREALRALEFLGLIETRRGEGTYMC
EIGSHQLVDLLAMFLLENERAKADLAETKWLVERLLLELFCQRQGEEAIGRLEKTVRQKPIDFERFFQTIAEAAGNYLLV
RIWRALSAFAAAFAPKPSLADSFYDQLLAALKKRDSAEAIAVWEAHRPWPLSKKS

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=221, Percent_Identity=30.316742081448, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786303, Length=157, Percent_Identity=29.9363057324841, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24404; Mature: 24404

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNRREGSSLNDEKVYAETLKHIHRLIVQDGLAPGDKLPSERELAERLGVGRSSVREAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
RALEFLGLIETRRGEGTYMCEIGSHQLVDLLAMFLLENERAKADLAETKWLVERLLLELF
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
CQRQGEEAIGRLEKTVRQKPIDFERFFQTIAEAAGNYLLVRIWRALSAFAAAFAPKPSLA
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHH
DSFYDQLLAALKKRDSAEAIAVWEAHRPWPLSKKS
HHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCC
>Mature Secondary Structure
MLVNRREGSSLNDEKVYAETLKHIHRLIVQDGLAPGDKLPSERELAERLGVGRSSVREAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
RALEFLGLIETRRGEGTYMCEIGSHQLVDLLAMFLLENERAKADLAETKWLVERLLLELF
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
CQRQGEEAIGRLEKTVRQKPIDFERFFQTIAEAAGNYLLVRIWRALSAFAAAFAPKPSLA
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHH
DSFYDQLLAALKKRDSAEAIAVWEAHRPWPLSKKS
HHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]