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The map label for this gene is speH [H]

Identifier: 138896286

GI number: 138896286

Start: 2756862

End: 2757302

Strand: Reverse

Name: speH [H]

Synonym: GTNG_2649

Alternate gene names: 138896286

Gene position: 2757302-2756862 (Counterclockwise)

Preceding gene: 138896287

Following gene: 138896285

Centisome position: 77.66

GC content: 45.58

Gene sequence:

>441_bases
ATGCCATTTTGCAAACGACAATCTGTTTTTTATTTGAGAAAATTGGTTAAAAGGGGGATTCTTTGCATGGATACGATGGG
TCGTCACGTTATCTCGGAACTCTGGGGATGCGACTTTGACAAACTGAATGATATCGATTTTATTGAAAAAACATTTGTTG
ACGCCGCACTAAAATCGGGGGCGGAAATTCGTGAAGTCGCGTTCCATAAATTCGCTCCACAAGGCGTAAGCGGAGTTGTC
ATTATTTCGGAATCTCATTTAACAATTCACACGTTCCCTGAACATGGCTATGCGAGTATTGATGTGTATACATGCGGCCA
TTTAGACCCGACGATTGCCGCTGACTACATCGCAGAACAGCTCGGCGCACAAACGCGAGAAACGATTGAACTTCCGCGCG
GCATGCGTCCAATCGAAGTGAAAAAGGCGCACGCGCTGTAA

Upstream 100 bases:

>100_bases
AGTATACTATGTCTCGTGAACTTCTTAACGGCAAAGGTAATGTGACTACTTAAAGGGTTAGGACCTCTTAGGACTAACTT
TCCCCCCGTGGTAGTTATAC

Downstream 100 bases:

>100_bases
TTCCATAACGACGGAACCGAAAGGAGCGTAAGCGGAACGCTCCTTTTTTTATTCTTCGACGGTACAACAGCGGTGAAAAT
CATGGTATGATGGAAGAAAA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MPFCKRQSVFYLRKLVKRGILCMDTMGRHVISELWGCDFDKLNDIDFIEKTFVDAALKSGAEIREVAFHKFAPQGVSGVV
IISESHLTIHTFPEHGYASIDVYTCGHLDPTIAADYIAEQLGAQTRETIELPRGMRPIEVKKAHAL

Sequences:

>Translated_146_residues
MPFCKRQSVFYLRKLVKRGILCMDTMGRHVISELWGCDFDKLNDIDFIEKTFVDAALKSGAEIREVAFHKFAPQGVSGVV
IISESHLTIHTFPEHGYASIDVYTCGHLDPTIAADYIAEQLGAQTRETIELPRGMRPIEVKKAHAL
>Mature_145_residues
PFCKRQSVFYLRKLVKRGILCMDTMGRHVISELWGCDFDKLNDIDFIEKTFVDAALKSGAEIREVAFHKFAPQGVSGVVI
ISESHLTIHTFPEHGYASIDVYTCGHLDPTIAADYIAEQLGAQTRETIELPRGMRPIEVKKAHAL

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 16420; Mature: 16289

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFCKRQSVFYLRKLVKRGILCMDTMGRHVISELWGCDFDKLNDIDFIEKTFVDAALKSG
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
AEIREVAFHKFAPQGVSGVVIISESHLTIHTFPEHGYASIDVYTCGHLDPTIAADYIAEQ
CHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHH
LGAQTRETIELPRGMRPIEVKKAHAL
HCCHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PFCKRQSVFYLRKLVKRGILCMDTMGRHVISELWGCDFDKLNDIDFIEKTFVDAALKSG
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
AEIREVAFHKFAPQGVSGVVIISESHLTIHTFPEHGYASIDVYTCGHLDPTIAADYIAEQ
CHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHH
LGAQTRETIELPRGMRPIEVKKAHAL
HCCHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA