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The map label for this gene is uvrC [H]

Identifier: 138896241

GI number: 138896241

Start: 2711446

End: 2713224

Strand: Reverse

Name: uvrC [H]

Synonym: GTNG_2604

Alternate gene names: 138896241

Gene position: 2713224-2711446 (Counterclockwise)

Preceding gene: 138896242

Following gene: 138896238

Centisome position: 76.42

GC content: 49.86

Gene sequence:

>1779_bases
ATGACCATGAACGACCGGCTGAAAGAAAAGCTGTCCGTGCTGCCAGAGCAGCCGGGCTGCTATTTAATGAAAGACAAACA
CGGAACGGTCATTTACGTCGGCAAGGCAAAGTCGCTGAAAGCGCGCGTCCGCTCGTATTTTACCGGGACGCACGAAGGCA
AGACGCAGCGACTTGTCGAGGAAATTGCCGATTTTGAATATATTGTTACCTCATCAAATGCCGAGGCGCTCATTTTGGAA
ATGAACTTGATTAAAAAGCATGACCCGAAATACAACGTCATGCTGAAAGGCGATGAAAGTTATCCATTTATTAAAATTAC
CGCAGAAAAGCATCCGCGATTGCTTATTACCCGCAAAGTGAAAAAAGACGGCGGCAAATATTTCGGTCCGTACCCGAACG
TGCAGGCGGCCCGCGAAACGAAAAAGTTGCTCGACCGTTTATATCCGCTCCGCAAATGCTCGACGCTGCCTTCGCGTGTT
TGCTTATATTACCATATGGGACAGTGTCTTGCTCCGTGCGTTTACCCGGTGTCGGATGAGCAAAACAAAGCCATGGTCGA
GCAAGTCGTTCGTTTTTTAAACGGTGGCTATCAAGAGGTAAAGCGGGAGCTGACGGAAAAAATGCATCAGGCGGCCGAAG
CGCTCGAGTTTGAGCGGGCGAAAGAATACCGTGACCAAATCGCGGCGATTGAGATGACGATGGAAAAACAAAAAATCGTG
TTCAACGATTTCATCGATCGCGATGTGTTCGGCTATGCATATGACAAAGGTTGGATGTGCGTACAAGTGTTTTTCCTTCG
CCAAGGGAAGCTGATTGAGCGCGATGTGTCCATTTTCCCTCTTTACCAAGACCCGGATGAGGAAATGCTCACATTTTTAG
GTCAGTTTTATACGAAGGCACACCATTTAAAGCCAAAAGAAGTTGTCTTGCCGACCGACATCGACGGTGAGCTCGTCCGC
GAGCTGCTTGGCGTCCATGTCGTTCAGCCGAAAAAAGGGAAGAAAAAAGAACTGATCGAGCTGGCGAACAAAAATGCTGC
CATCGCCTTGAAAGAAAAGTTTTATTTTATTGAACGCGATGAAGAAAGGACGATTAAAGCGATCGAACGGCTCGGGGAGC
TGCTCGGCATTCCGACGCCGCGCCGCATTGAGGCGTTTGATAACTCGAACATATACGGAGCCGATCCGGTCTCAGCGCTC
GTTGTCTTCCTTGACGGCAAGCCGGCGAAAAAAGAGTACCGGAAATATAAGGTGAAAACGGTCGAGGGGCCGAACGACTA
TGAGTCGATGCGCGAAGTCGTGCGCCGACGCTATACACGCGTGCTGAAAGAAAGACTGCCGCTTCCTGATTTGATCATTA
TCGATGGCGGAAAAGGCCATTTGTCCGCAGTGCGCGATGTACTTGAAAACGAACTCGGCCTCGATGTACCGCTCGCCGGG
CTGGCGAAAGACGAAAAACATCGCACATCGGAGCTTATTGCTGGTGACCCGCCAGCCGTTGTGCCGCTTGACAGGCAAAG
CCAAGAGTTTTATTTGCTGCAACGCATTCAAGATGAAGTGCACCGGTTTGCGGTGACGTTCCACCGTCAGACGCGGCAAA
AAACGATGCTCCATTCCATTCTTGATGACATCCCTGGTGTCGGGGCAAAGCGAAAAAAGGCGTTATTAAACTATTTTGGC
TCCGTGAAAAAAATGAAAGAGGCGACGGTGGAAGAGCTGCAGCGGGCAAACATCCCGCGGTCGGTGGCGGAGAAAATTTA
TGAAAAACTGCACGAATAA

Upstream 100 bases:

>100_bases
CTATGTGCGGAGAGGGAAAACGTATCGTTCAAGTTCGCTCGACGATCCGGTGTATGGGACGATTACGCTGGGCGAATGGG
TCGAGGAATAGGATGGAGTG

Downstream 100 bases:

>100_bases
TGGCGCAAAGGGCGTCCCAGAGGGTTGGGACGCCCTTTGTTCACTTGATTCTCCTTGTCGGAGAAGCCTTTTGTGTTTGT
TGTCGAAAACGTGAGGCAAT

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MTMNDRLKEKLSVLPEQPGCYLMKDKHGTVIYVGKAKSLKARVRSYFTGTHEGKTQRLVEEIADFEYIVTSSNAEALILE
MNLIKKHDPKYNVMLKGDESYPFIKITAEKHPRLLITRKVKKDGGKYFGPYPNVQAARETKKLLDRLYPLRKCSTLPSRV
CLYYHMGQCLAPCVYPVSDEQNKAMVEQVVRFLNGGYQEVKRELTEKMHQAAEALEFERAKEYRDQIAAIEMTMEKQKIV
FNDFIDRDVFGYAYDKGWMCVQVFFLRQGKLIERDVSIFPLYQDPDEEMLTFLGQFYTKAHHLKPKEVVLPTDIDGELVR
ELLGVHVVQPKKGKKKELIELANKNAAIALKEKFYFIERDEERTIKAIERLGELLGIPTPRRIEAFDNSNIYGADPVSAL
VVFLDGKPAKKEYRKYKVKTVEGPNDYESMREVVRRRYTRVLKERLPLPDLIIIDGGKGHLSAVRDVLENELGLDVPLAG
LAKDEKHRTSELIAGDPPAVVPLDRQSQEFYLLQRIQDEVHRFAVTFHRQTRQKTMLHSILDDIPGVGAKRKKALLNYFG
SVKKMKEATVEELQRANIPRSVAEKIYEKLHE

Sequences:

>Translated_592_residues
MTMNDRLKEKLSVLPEQPGCYLMKDKHGTVIYVGKAKSLKARVRSYFTGTHEGKTQRLVEEIADFEYIVTSSNAEALILE
MNLIKKHDPKYNVMLKGDESYPFIKITAEKHPRLLITRKVKKDGGKYFGPYPNVQAARETKKLLDRLYPLRKCSTLPSRV
CLYYHMGQCLAPCVYPVSDEQNKAMVEQVVRFLNGGYQEVKRELTEKMHQAAEALEFERAKEYRDQIAAIEMTMEKQKIV
FNDFIDRDVFGYAYDKGWMCVQVFFLRQGKLIERDVSIFPLYQDPDEEMLTFLGQFYTKAHHLKPKEVVLPTDIDGELVR
ELLGVHVVQPKKGKKKELIELANKNAAIALKEKFYFIERDEERTIKAIERLGELLGIPTPRRIEAFDNSNIYGADPVSAL
VVFLDGKPAKKEYRKYKVKTVEGPNDYESMREVVRRRYTRVLKERLPLPDLIIIDGGKGHLSAVRDVLENELGLDVPLAG
LAKDEKHRTSELIAGDPPAVVPLDRQSQEFYLLQRIQDEVHRFAVTFHRQTRQKTMLHSILDDIPGVGAKRKKALLNYFG
SVKKMKEATVEELQRANIPRSVAEKIYEKLHE
>Mature_591_residues
TMNDRLKEKLSVLPEQPGCYLMKDKHGTVIYVGKAKSLKARVRSYFTGTHEGKTQRLVEEIADFEYIVTSSNAEALILEM
NLIKKHDPKYNVMLKGDESYPFIKITAEKHPRLLITRKVKKDGGKYFGPYPNVQAARETKKLLDRLYPLRKCSTLPSRVC
LYYHMGQCLAPCVYPVSDEQNKAMVEQVVRFLNGGYQEVKRELTEKMHQAAEALEFERAKEYRDQIAAIEMTMEKQKIVF
NDFIDRDVFGYAYDKGWMCVQVFFLRQGKLIERDVSIFPLYQDPDEEMLTFLGQFYTKAHHLKPKEVVLPTDIDGELVRE
LLGVHVVQPKKGKKKELIELANKNAAIALKEKFYFIERDEERTIKAIERLGELLGIPTPRRIEAFDNSNIYGADPVSALV
VFLDGKPAKKEYRKYKVKTVEGPNDYESMREVVRRRYTRVLKERLPLPDLIIIDGGKGHLSAVRDVLENELGLDVPLAGL
AKDEKHRTSELIAGDPPAVVPLDRQSQEFYLLQRIQDEVHRFAVTFHRQTRQKTMLHSILDDIPGVGAKRKKALLNYFGS
VKKMKEATVEELQRANIPRSVAEKIYEKLHE

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=619, Percent_Identity=38.1260096930533, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 68297; Mature: 68166

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNDRLKEKLSVLPEQPGCYLMKDKHGTVIYVGKAKSLKARVRSYFTGTHEGKTQRLVE
CCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHH
EIADFEYIVTSSNAEALILEMNLIKKHDPKYNVMLKGDESYPFIKITAEKHPRLLITRKV
HHHCCEEEEECCCCCEEEEEEHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEHH
KKDGGKYFGPYPNVQAARETKKLLDRLYPLRKCSTLPSRVCLYYHMGQCLAPCVYPVSDE
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
QNKAMVEQVVRFLNGGYQEVKRELTEKMHQAAEALEFERAKEYRDQIAAIEMTMEKQKIV
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNDFIDRDVFGYAYDKGWMCVQVFFLRQGKLIERDVSIFPLYQDPDEEMLTFLGQFYTKA
HHHHHCCCHHCEEECCCHHHHHHHHHHCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHH
HHLKPKEVVLPTDIDGELVRELLGVHVVQPKKGKKKELIELANKNAAIALKEKFYFIERD
HCCCCCCEEECCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHCCCCEEEEEEEEEEEECC
EERTIKAIERLGELLGIPTPRRIEAFDNSNIYGADPVSALVVFLDGKPAKKEYRKYKVKT
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHEEEEEECCCCCHHHHHHEEEEE
VEGPNDYESMREVVRRRYTRVLKERLPLPDLIIIDGGKGHLSAVRDVLENELGLDVPLAG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
LAKDEKHRTSELIAGDPPAVVPLDRQSQEFYLLQRIQDEVHRFAVTFHRQTRQKTMLHSI
CCCCHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDIPGVGAKRKKALLNYFGSVKKMKEATVEELQRANIPRSVAEKIYEKLHE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TMNDRLKEKLSVLPEQPGCYLMKDKHGTVIYVGKAKSLKARVRSYFTGTHEGKTQRLVE
CCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHH
EIADFEYIVTSSNAEALILEMNLIKKHDPKYNVMLKGDESYPFIKITAEKHPRLLITRKV
HHHCCEEEEECCCCCEEEEEEHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEHH
KKDGGKYFGPYPNVQAARETKKLLDRLYPLRKCSTLPSRVCLYYHMGQCLAPCVYPVSDE
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
QNKAMVEQVVRFLNGGYQEVKRELTEKMHQAAEALEFERAKEYRDQIAAIEMTMEKQKIV
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNDFIDRDVFGYAYDKGWMCVQVFFLRQGKLIERDVSIFPLYQDPDEEMLTFLGQFYTKA
HHHHHCCCHHCEEECCCHHHHHHHHHHCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHH
HHLKPKEVVLPTDIDGELVRELLGVHVVQPKKGKKKELIELANKNAAIALKEKFYFIERD
HCCCCCCEEECCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHCCCCEEEEEEEEEEEECC
EERTIKAIERLGELLGIPTPRRIEAFDNSNIYGADPVSALVVFLDGKPAKKEYRKYKVKT
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHEEEEEECCCCCHHHHHHEEEEE
VEGPNDYESMREVVRRRYTRVLKERLPLPDLIIIDGGKGHLSAVRDVLENELGLDVPLAG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
LAKDEKHRTSELIAGDPPAVVPLDRQSQEFYLLQRIQDEVHRFAVTFHRQTRQKTMLHSI
CCCCHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDIPGVGAKRKKALLNYFGSVKKMKEATVEELQRANIPRSVAEKIYEKLHE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA