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The map label for this gene is glcK [H]

Identifier: 138896018

GI number: 138896018

Start: 2495143

End: 2496096

Strand: Reverse

Name: glcK [H]

Synonym: GTNG_2381

Alternate gene names: 138896018

Gene position: 2496096-2495143 (Counterclockwise)

Preceding gene: 138896019

Following gene: 138896017

Centisome position: 70.31

GC content: 56.92

Gene sequence:

>954_bases
ATGCAACAATGGTTGGTAGGTATTGATCTTGGCGGTACAACGATCAAAATGGCGTTTGTGACAACTAGCGGCGATATCGT
GCATAAATGGGAGATCCCAACCAATATTTCGAATCGCGGGGAGCATATTGTCGCTGATATTGCCCGGTCGCTTGATGAGA
CGCTCGTCAAGCTTAATGCGACGAAAGAGCAATTGCTCGCAATCGGCATCGGCGCCCCGGGGCCGGTGCAAGAGGAAACG
GGGACGCTGTATGAGGCCATCAACTTAGGATGGACGAATTATCCTTTGAAACAGCAATTGGAAGCGGCAACAATGTTGCC
GGTGGCTGTGGATAACGACGTCAATATCGCTGCGTTCGGTGAAATGTGGAAAGGAGCTGGGGGCGGTGCACGCCATTTGC
TGTTTGTCACGCTCGGCACCGGCGTGGGCGGCGGTGTGATCTCCAATGGCACCATCGTGCGCGGGACGAACGGTGCCGGT
GGGGAGCTCGGCCATATGACGATGGTCGTCGATGGAGGCGCGCCATGTAATTGCGGAAAAACCGGTTGTCTTGAAACGAT
TGCGTCGGCGACCGGAATCGTGCGGATCACTAACGAAAAACTGGCCGCTGACGAGCAGCCAAGCGTGCTGCGCGGCGGAG
AGGTCACCGCCAAAGCTGTGTTTGATGCCGCCAAAGCAGGTGATCCGCTCGCGCTACAAATCGTTGACGAAGTGACGCAC
TACCTCGGTTTGGCGTTGGCGAACGCCGCCAATGTAACCAATCCGGAGAAAATCGTCATCGGCGGCGGTGTCTCGAAAGC
AGGCGATATACTCGTTGAGCATGTGACCACCCATTTCCGTCGTTTCGCTTTTCCACGCGTCGCTGCTGGAGCTGAGATCG
CCTTGGCGACGCTCGGCAATGATGCGGGTGTCATCGGCGGCGCCTGGCTGGCCAAAGCGCTTGCCGGTGCCTAA

Upstream 100 bases:

>100_bases
CAGCTGATCGATGCCAAACAGTTGCAGGCCGCACTATTCATTTTGCGGCATGAAGCGCAAATCGAGCGAGAAAAACGAAT
GACAAAAGGATGAGGACGAA

Downstream 100 bases:

>100_bases
AACAACAACGGCTGGCTGCCATATGGCGGCAAGCCGTTGTTTTCATTTTTTGGCGTCCATTGACATATGTTGGAGATAGA
AGAATAGGAAGGAGAGACGG

Product: glucose kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQQWLVGIDLGGTTIKMAFVTTSGDIVHKWEIPTNISNRGEHIVADIARSLDETLVKLNATKEQLLAIGIGAPGPVQEET
GTLYEAINLGWTNYPLKQQLEAATMLPVAVDNDVNIAAFGEMWKGAGGGARHLLFVTLGTGVGGGVISNGTIVRGTNGAG
GELGHMTMVVDGGAPCNCGKTGCLETIASATGIVRITNEKLAADEQPSVLRGGEVTAKAVFDAAKAGDPLALQIVDEVTH
YLGLALANAANVTNPEKIVIGGGVSKAGDILVEHVTTHFRRFAFPRVAAGAEIALATLGNDAGVIGGAWLAKALAGA

Sequences:

>Translated_317_residues
MQQWLVGIDLGGTTIKMAFVTTSGDIVHKWEIPTNISNRGEHIVADIARSLDETLVKLNATKEQLLAIGIGAPGPVQEET
GTLYEAINLGWTNYPLKQQLEAATMLPVAVDNDVNIAAFGEMWKGAGGGARHLLFVTLGTGVGGGVISNGTIVRGTNGAG
GELGHMTMVVDGGAPCNCGKTGCLETIASATGIVRITNEKLAADEQPSVLRGGEVTAKAVFDAAKAGDPLALQIVDEVTH
YLGLALANAANVTNPEKIVIGGGVSKAGDILVEHVTTHFRRFAFPRVAAGAEIALATLGNDAGVIGGAWLAKALAGA
>Mature_317_residues
MQQWLVGIDLGGTTIKMAFVTTSGDIVHKWEIPTNISNRGEHIVADIARSLDETLVKLNATKEQLLAIGIGAPGPVQEET
GTLYEAINLGWTNYPLKQQLEAATMLPVAVDNDVNIAAFGEMWKGAGGGARHLLFVTLGTGVGGGVISNGTIVRGTNGAG
GELGHMTMVVDGGAPCNCGKTGCLETIASATGIVRITNEKLAADEQPSVLRGGEVTAKAVFDAAKAGDPLALQIVDEVTH
YLGLALANAANVTNPEKIVIGGGVSKAGDILVEHVTTHFRRFAFPRVAAGAEIALATLGNDAGVIGGAWLAKALAGA

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=265, Percent_Identity=32.4528301886792, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI298566325, Length=265, Percent_Identity=32.4528301886792, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4885285, Length=265, Percent_Identity=32.4528301886792, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI190014632, Length=265, Percent_Identity=32.4528301886792, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787878, Length=271, Percent_Identity=32.8413284132841, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786891, Length=271, Percent_Identity=31.3653136531365, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87081733, Length=322, Percent_Identity=31.3664596273292, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787363, Length=317, Percent_Identity=29.9684542586751, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082127, Length=252, Percent_Identity=28.1746031746032, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082230, Length=260, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790522, Length=282, Percent_Identity=27.3049645390071, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 32535; Mature: 32535

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00626 RCC1_2 ; PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQWLVGIDLGGTTIKMAFVTTSGDIVHKWEIPTNISNRGEHIVADIARSLDETLVKLNA
CCCEEEEEECCCCEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TKEQLLAIGIGAPGPVQEETGTLYEAINLGWTNYPLKQQLEAATMLPVAVDNDVNIAAFG
CCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCEEEEH
EMWKGAGGGARHLLFVTLGTGVGGGVISNGTIVRGTNGAGGELGHMTMVVDGGAPCNCGK
HHHCCCCCCCEEEEEEEECCCCCCCEECCCEEEECCCCCCCCCCEEEEEEECCCCCCCCC
TGCLETIASATGIVRITNEKLAADEQPSVLRGGEVTAKAVFDAAKAGDPLALQIVDEVTH
HHHHHHHHHCCCEEEECCCHHCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHH
YLGLALANAANVTNPEKIVIGGGVSKAGDILVEHVTTHFRRFAFPRVAAGAEIALATLGN
HHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEEECC
DAGVIGGAWLAKALAGA
CCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQQWLVGIDLGGTTIKMAFVTTSGDIVHKWEIPTNISNRGEHIVADIARSLDETLVKLNA
CCCEEEEEECCCCEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TKEQLLAIGIGAPGPVQEETGTLYEAINLGWTNYPLKQQLEAATMLPVAVDNDVNIAAFG
CCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCEEEEH
EMWKGAGGGARHLLFVTLGTGVGGGVISNGTIVRGTNGAGGELGHMTMVVDGGAPCNCGK
HHHCCCCCCCEEEEEEEECCCCCCCEECCCEEEECCCCCCCCCCEEEEEEECCCCCCCCC
TGCLETIASATGIVRITNEKLAADEQPSVLRGGEVTAKAVFDAAKAGDPLALQIVDEVTH
HHHHHHHHHCCCEEEECCCHHCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHH
YLGLALANAANVTNPEKIVIGGGVSKAGDILVEHVTTHFRRFAFPRVAAGAEIALATLGN
HHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEEECC
DAGVIGGAWLAKALAGA
CCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]