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The map label for this gene is yhdN [H]

Identifier: 138895998

GI number: 138895998

Start: 2477729

End: 2478712

Strand: Reverse

Name: yhdN [H]

Synonym: GTNG_2361

Alternate gene names: 138895998

Gene position: 2478712-2477729 (Counterclockwise)

Preceding gene: 138895999

Following gene: 138895997

Centisome position: 69.82

GC content: 53.86

Gene sequence:

>984_bases
ATGCAATACCGGCAGTTAGGAAGTACCGACCTTCGAGTGAGCGAACTCAGCTTCGGTACGTGGGCGATCGGCGGCTCATG
GGGGAAAGTCGACGATCAAGAATCGTTGCGCGCCCTCGCCTACGCCATTGAGCAGGGGGTTAACTTTTTTGATACGGCTG
ATGTGTACGGCAACGGCCATAGCGAGGAGCTGTTGGCGAAGGCGACAAAAGGGAAGGAAGACCGCATCTACATAGCAACG
AAGTTTTGTCGCGCCGGCGATATCCATGACCCAAACAACTATTCCGAAGCGTCCGTGCGCGCATATTGTGAGGCAAGCTT
AAAACGGCTCGGCCGCGAGACGATTGATTTGTATCAAATTCATTGCCCGCCGTTTTCCATTTTAAAGCAAGGCGCCGTGT
TTGAAGTGTTAGAGAAGTTAAAGCAGGAAGGAAAAATCCGCTATTACGGCGTCAGCGTTGAAACGATAGAAGAAGGGCTG
TACGTCATCGAGCATTCGCAGGCAAGCGCGCTGCAAGTCATCTTCAACATTTTGCGGCAAAAGCCGCTCGAGCGTCTGCT
TCCGGAAGCGAAACGGCGCGGCGTCGGCATTTTGGTCCGCCTTCCGCTCGCCAGCGGACTGCTGACTGGTAAGTTCACGA
AGCAAACGACGTTTGCTGAGGATGATCACCGCCATTTCAACCGCAACGGTGAACAGTTTAATGTAGGGGAAACGTTCGGC
GGCTTGGAGTTTGAAAAAGGGGTGGAGCTCGCCGACAAGCTGCGTTGGATTGCCGATGGGCGCGGCAGCATGGCGAAAGC
GGCGCTCCGATGGGTCATTGACCATGAAGAAGTGACGTGCGCTATTCCAGGATTTAAAACGGTGAAACAAGTCGAAGAAA
ACTTGGCGGCGTTGGCGGTGCCATCGTTCAGTGAAGAAGAAATGGCGCGGCTTCGCCAGTTTTACGAGACTGAAGTGCAT
CCGCACATTCGCGGGGCATACTAA

Upstream 100 bases:

>100_bases
TTTAGCCCGGCTGCGCCGCTATTGCAGCGTTGACAGAAAAGTTTAGTTAGTTTATCATATAAACTAATGGCGGTGATCCA
TGAATAAGGGGGAGTGAGAC

Downstream 100 bases:

>100_bases
ACGAAAAAAGGATGACTAGTCACGTGCGGACAGGAAACATTACTCTTGTCAAAAAAATGAATAAACAGCTTGTGTTGAAA
TTGATTCGCGACCAACATCC

Product: putative oxidoreductase protein

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MQYRQLGSTDLRVSELSFGTWAIGGSWGKVDDQESLRALAYAIEQGVNFFDTADVYGNGHSEELLAKATKGKEDRIYIAT
KFCRAGDIHDPNNYSEASVRAYCEASLKRLGRETIDLYQIHCPPFSILKQGAVFEVLEKLKQEGKIRYYGVSVETIEEGL
YVIEHSQASALQVIFNILRQKPLERLLPEAKRRGVGILVRLPLASGLLTGKFTKQTTFAEDDHRHFNRNGEQFNVGETFG
GLEFEKGVELADKLRWIADGRGSMAKAALRWVIDHEEVTCAIPGFKTVKQVEENLAALAVPSFSEEEMARLRQFYETEVH
PHIRGAY

Sequences:

>Translated_327_residues
MQYRQLGSTDLRVSELSFGTWAIGGSWGKVDDQESLRALAYAIEQGVNFFDTADVYGNGHSEELLAKATKGKEDRIYIAT
KFCRAGDIHDPNNYSEASVRAYCEASLKRLGRETIDLYQIHCPPFSILKQGAVFEVLEKLKQEGKIRYYGVSVETIEEGL
YVIEHSQASALQVIFNILRQKPLERLLPEAKRRGVGILVRLPLASGLLTGKFTKQTTFAEDDHRHFNRNGEQFNVGETFG
GLEFEKGVELADKLRWIADGRGSMAKAALRWVIDHEEVTCAIPGFKTVKQVEENLAALAVPSFSEEEMARLRQFYETEVH
PHIRGAY
>Mature_327_residues
MQYRQLGSTDLRVSELSFGTWAIGGSWGKVDDQESLRALAYAIEQGVNFFDTADVYGNGHSEELLAKATKGKEDRIYIAT
KFCRAGDIHDPNNYSEASVRAYCEASLKRLGRETIDLYQIHCPPFSILKQGAVFEVLEKLKQEGKIRYYGVSVETIEEGL
YVIEHSQASALQVIFNILRQKPLERLLPEAKRRGVGILVRLPLASGLLTGKFTKQTTFAEDDHRHFNRNGEQFNVGETFG
GLEFEKGVELADKLRWIADGRGSMAKAALRWVIDHEEVTCAIPGFKTVKQVEENLAALAVPSFSEEEMARLRQFYETEVH
PHIRGAY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=28.343949044586, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI27436962, Length=314, Percent_Identity=28.343949044586, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436966, Length=330, Percent_Identity=25.4545454545455, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27436969, Length=317, Percent_Identity=26.4984227129338, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4504825, Length=315, Percent_Identity=26.3492063492064, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=27.5541795665635, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI223718702, Length=283, Percent_Identity=28.9752650176678, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI41327764, Length=283, Percent_Identity=27.9151943462898, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI41152114, Length=283, Percent_Identity=28.2685512367491, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=29.1176470588235, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081735, Length=337, Percent_Identity=29.3768545994065, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789375, Length=332, Percent_Identity=31.3253012048193, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788081, Length=312, Percent_Identity=26.2820512820513, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=26.2569832402235, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=306, Percent_Identity=27.4509803921569, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=27.3239436619718, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=315, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646155, Length=326, Percent_Identity=29.7546012269939, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=33.4841628959276, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24640980, Length=353, Percent_Identity=25.2124645892351, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549126, Length=343, Percent_Identity=25.9475218658892, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36837; Mature: 36837

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRQLGSTDLRVSELSFGTWAIGGSWGKVDDQESLRALAYAIEQGVNFFDTADVYGNGH
CCCCCCCCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHCCCCC
SEELLAKATKGKEDRIYIATKFCRAGDIHDPNNYSEASVRAYCEASLKRLGRETIDLYQI
HHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEEE
HCPPFSILKQGAVFEVLEKLKQEGKIRYYGVSVETIEEGLYVIEHSQASALQVIFNILRQ
ECCCHHHHHCCCHHHHHHHHHHCCCEEEEECCHHHHHCCEEEEECCCHHHHHHHHHHHHH
KPLERLLPEAKRRGVGILVRLPLASGLLTGKFTKQTTFAEDDHRHFNRNGEQFNVGETFG
CHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCC
GLEFEKGVELADKLRWIADGRGSMAKAALRWVIDHEEVTCAIPGFKTVKQVEENLAALAV
CCCHHHCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHEEEC
PSFSEEEMARLRQFYETEVHPHIRGAY
CCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQYRQLGSTDLRVSELSFGTWAIGGSWGKVDDQESLRALAYAIEQGVNFFDTADVYGNGH
CCCCCCCCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHCCCCC
SEELLAKATKGKEDRIYIATKFCRAGDIHDPNNYSEASVRAYCEASLKRLGRETIDLYQI
HHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEEE
HCPPFSILKQGAVFEVLEKLKQEGKIRYYGVSVETIEEGLYVIEHSQASALQVIFNILRQ
ECCCHHHHHCCCHHHHHHHHHHCCCEEEEECCHHHHHCCEEEEECCCHHHHHHHHHHHHH
KPLERLLPEAKRRGVGILVRLPLASGLLTGKFTKQTTFAEDDHRHFNRNGEQFNVGETFG
CHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCC
GLEFEKGVELADKLRWIADGRGSMAKAALRWVIDHEEVTCAIPGFKTVKQVEENLAALAV
CCCHHHCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHEEEC
PSFSEEEMARLRQFYETEVHPHIRGAY
CCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]