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The map label for this gene is cobD [H]

Identifier: 138895837

GI number: 138895837

Start: 2318826

End: 2319797

Strand: Reverse

Name: cobD [H]

Synonym: GTNG_2196

Alternate gene names: 138895837

Gene position: 2319797-2318826 (Counterclockwise)

Preceding gene: 138895838

Following gene: 138895836

Centisome position: 65.34

GC content: 59.88

Gene sequence:

>972_bases
ATGACGCATCTGTTGGCGCTGACGTTGGCATTGTTTCTTGACGCACTGTTTGGTGACCCGCGCTGGCTGCCGCATCCGGT
GCGCGGGATGGGAGGACTGATTGCTTATTTCGACCAGCGCTGGAATCAAGGAAGCGGCCGCCGGGCTAAGGGCGTGGCGG
CCGTGGCCGCCGTGCTGGCCATCGTGTATGGGGTGTCCGCGCTCATCGTTCATATGAGCTATGCCTTGTCAGTATACATT
GGCGTGGCGGTCGAAGCGGTGCTCATTTTTACGACTATTGCGACAAAAAGTCTTGCTGAAGCAGCTGAGGATGTGCGGCG
GCCGCTCGAAGCGGGCGATCTCCCGGAGGCGCGGCGCGCGCTGTCGATGATCGTCGGCCGCGATACCAAGCGGCTCGATG
AAGCCGGCATTACCCGTGCCTGCGTGGAAACGGTGGCGGAAAATACGAGCGACGGCGTTACCGCCCCTCTCTTTTACGCA
GCCATTGGTGGAGCGCCGCTCGCCTTATTGTATCGGGCGGTGAACACGTGCGATTCGATGATCGGTTATAAAAATGAGAA
GTATGGCGAATTTGGCTGGGCAGCCGCTCGGCTGGATGATGTGCTGAACTATATTCCGGCTCGGTTGACGGCACTTGTCA
TGGTGTTCATTTATGGTGGTCGCCGGCTTCGTCGCTCTTTGGCAGTTTTGTTTCGCGATGCCCGCCGCCATCCGAGCCCC
AACAGCGGTTGGCTCGAGGCGGCGATGGCTGGGCTGCTCGGGGTGCAGCTGGGTGGAACGAATACATATGGTGGCGTTGT
TTCCGAGCGGCCGACGATCGGCCGCCCGGACGTCCCGCTTCGCTCCGTCCATATTCGTCGGGCGGTCGGCATCATGATCG
GAACGGTGCTTGTTTTTACGTTATGGCTATGGATCGGAGGGATGATCGTTGTATTGGCCGGCGCATGGGGCGAATCCGCA
CGCGCTCTATAA

Upstream 100 bases:

>100_bases
ATGCTGGGACGGCGACTGAGCTTGGCCGCGAGCTCGGTCGGCTCGTGTATGAGGCGACGATCGAGGCACTCGACCGCTAT
GAGCGACGGAGGGGAAGACG

Downstream 100 bases:

>100_bases
GCAGTGCGGACTTACCCCTCCACATAAGTATGTTGATTTCAGCGTCAATACGAACCCGTACCAGCTGCCGCTTTCCGCCT
GGCCGGACAGTGAGGAGTGG

Product: cobalamin biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTHLLALTLALFLDALFGDPRWLPHPVRGMGGLIAYFDQRWNQGSGRRAKGVAAVAAVLAIVYGVSALIVHMSYALSVYI
GVAVEAVLIFTTIATKSLAEAAEDVRRPLEAGDLPEARRALSMIVGRDTKRLDEAGITRACVETVAENTSDGVTAPLFYA
AIGGAPLALLYRAVNTCDSMIGYKNEKYGEFGWAAARLDDVLNYIPARLTALVMVFIYGGRRLRRSLAVLFRDARRHPSP
NSGWLEAAMAGLLGVQLGGTNTYGGVVSERPTIGRPDVPLRSVHIRRAVGIMIGTVLVFTLWLWIGGMIVVLAGAWGESA
RAL

Sequences:

>Translated_323_residues
MTHLLALTLALFLDALFGDPRWLPHPVRGMGGLIAYFDQRWNQGSGRRAKGVAAVAAVLAIVYGVSALIVHMSYALSVYI
GVAVEAVLIFTTIATKSLAEAAEDVRRPLEAGDLPEARRALSMIVGRDTKRLDEAGITRACVETVAENTSDGVTAPLFYA
AIGGAPLALLYRAVNTCDSMIGYKNEKYGEFGWAAARLDDVLNYIPARLTALVMVFIYGGRRLRRSLAVLFRDARRHPSP
NSGWLEAAMAGLLGVQLGGTNTYGGVVSERPTIGRPDVPLRSVHIRRAVGIMIGTVLVFTLWLWIGGMIVVLAGAWGESA
RAL
>Mature_322_residues
THLLALTLALFLDALFGDPRWLPHPVRGMGGLIAYFDQRWNQGSGRRAKGVAAVAAVLAIVYGVSALIVHMSYALSVYIG
VAVEAVLIFTTIATKSLAEAAEDVRRPLEAGDLPEARRALSMIVGRDTKRLDEAGITRACVETVAENTSDGVTAPLFYAA
IGGAPLALLYRAVNTCDSMIGYKNEKYGEFGWAAARLDDVLNYIPARLTALVMVFIYGGRRLRRSLAVLFRDARRHPSPN
SGWLEAAMAGLLGVQLGGTNTYGGVVSERPTIGRPDVPLRSVHIRRAVGIMIGTVLVFTLWLWIGGMIVVLAGAWGESAR
AL

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 34748; Mature: 34617

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
THLLALTLALFLDALFGDPRWLPHPVRGMGGLIAYFDQRWNQGSGRRAKGVAAVAAVLA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
IVYGVSALIVHMSYALSVYIGVAVEAVLIFTTIATKSLAEAAEDVRRPLEAGDLPEARRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LSMIVGRDTKRLDEAGITRACVETVAENTSDGVTAPLFYAAIGGAPLALLYRAVNTCDSM
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
IGYKNEKYGEFGWAAARLDDVLNYIPARLTALVMVFIYGGRRLRRSLAVLFRDARRHPSP
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
NSGWLEAAMAGLLGVQLGGTNTYGGVVSERPTIGRPDVPLRSVHIRRAVGIMIGTVLVFT
CCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LWLWIGGMIVVLAGAWGESARAL
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]