Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 138895803

GI number: 138895803

Start: 2291300

End: 2291887

Strand: Reverse

Name: plsC [H]

Synonym: GTNG_2162

Alternate gene names: 138895803

Gene position: 2291887-2291300 (Counterclockwise)

Preceding gene: 138895804

Following gene: 138895802

Centisome position: 64.55

GC content: 54.08

Gene sequence:

>588_bases
ATGAGGGTGGATTTTTATTCGTTGGCCAAAGGAGTGGTAAAAAGCATATTAACCCCTTTGTACCGCATTCAAGTTACCGG
GGTTGAGCAATTTCCAAAAGAAGGAGCGGTGCTTCTGTGCGCCAACCATATCAGCAACTTAGATCCGCCGATCGTCGGCA
TTACAGCACCGCGGCCGATCCGGTTTATGGCGAAAGAAGAATTGTTTCGCACCCCAGTGGTGAAAACGCTCGTCAAAAGC
TTGCACGCTTTTCCGGTTAAACGTGGCATGAGCGACCGTCAGGCGCTGCGCACAGGGATTGAGGTGCTGAAACAAGGAGA
GGTGCTCGGCATTTTTCCTGAAGGAACGCGCAGCAAAGACGGGCGTCTGAAACGGGCGCTGCCTGGCGTCGGTTTTTTCG
CCTTGCGCACCGATGCAGCTGTCGTCCCATGCGCGATCATCGGTCCGTATCGGCCGTTTGTGCCGCTCAAAGTCGTATAC
GGGGCGCCAATTGATATGGCGCCGCTTCGTGAGCGGAAGGCCAGTCCGGAAGAAGCGGCCGATTATATCATGGATCATAT
CCGCCAGCTGCTTGAACAACATCGATAA

Upstream 100 bases:

>100_bases
CGCTTCGCAAGGCGCCGGATGCGGTAGAAATTGATACGACGTCGCTGACGGTCGAGGAAGTGGCGGCGCGCATTATGGAA
ATTGTCAACGAAAGGATTGG

Downstream 100 bases:

>100_bases
GCATTATAGTACATGTTGATTGAGAAAATATGGTATACTAACTAGAAAAGCGTCCTTATTTTTGCCGACAGCCGGCCGCG
GCCTCGGCGCGAGGCGCGCT

Product: L-acyl-sn-glycerol-3-phosphate acetyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MRVDFYSLAKGVVKSILTPLYRIQVTGVEQFPKEGAVLLCANHISNLDPPIVGITAPRPIRFMAKEELFRTPVVKTLVKS
LHAFPVKRGMSDRQALRTGIEVLKQGEVLGIFPEGTRSKDGRLKRALPGVGFFALRTDAAVVPCAIIGPYRPFVPLKVVY
GAPIDMAPLRERKASPEEAADYIMDHIRQLLEQHR

Sequences:

>Translated_195_residues
MRVDFYSLAKGVVKSILTPLYRIQVTGVEQFPKEGAVLLCANHISNLDPPIVGITAPRPIRFMAKEELFRTPVVKTLVKS
LHAFPVKRGMSDRQALRTGIEVLKQGEVLGIFPEGTRSKDGRLKRALPGVGFFALRTDAAVVPCAIIGPYRPFVPLKVVY
GAPIDMAPLRERKASPEEAADYIMDHIRQLLEQHR
>Mature_195_residues
MRVDFYSLAKGVVKSILTPLYRIQVTGVEQFPKEGAVLLCANHISNLDPPIVGITAPRPIRFMAKEELFRTPVVKTLVKS
LHAFPVKRGMSDRQALRTGIEVLKQGEVLGIFPEGTRSKDGRLKRALPGVGFFALRTDAAVVPCAIIGPYRPFVPLKVVY
GAPIDMAPLRERKASPEEAADYIMDHIRQLLEQHR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 21682; Mature: 21682

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVDFYSLAKGVVKSILTPLYRIQVTGVEQFPKEGAVLLCANHISNLDPPIVGITAPRPI
CCCCHHHHHHHHHHHHHHHHHHEEECCHHHCCCCCCEEEEECHHCCCCCCEEEECCCCCH
RFMAKEELFRTPVVKTLVKSLHAFPVKRGMSDRQALRTGIEVLKQGEVLGIFPEGTRSKD
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCC
GRLKRALPGVGFFALRTDAAVVPCAIIGPYRPFVPLKVVYGAPIDMAPLRERKASPEEAA
CCHHHHCCCCCEEEEECCCCCCCHHEECCCCCCCCEEEEECCCCCCHHHHHHCCCHHHHH
DYIMDHIRQLLEQHR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVDFYSLAKGVVKSILTPLYRIQVTGVEQFPKEGAVLLCANHISNLDPPIVGITAPRPI
CCCCHHHHHHHHHHHHHHHHHHEEECCHHHCCCCCCEEEEECHHCCCCCCEEEECCCCCH
RFMAKEELFRTPVVKTLVKSLHAFPVKRGMSDRQALRTGIEVLKQGEVLGIFPEGTRSKD
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCC
GRLKRALPGVGFFALRTDAAVVPCAIIGPYRPFVPLKVVYGAPIDMAPLRERKASPEEAA
CCHHHHCCCCCEEEEECCCCCCCHHEECCCCCCCCEEEEECCCCCCHHHHHHCCCHHHHH
DYIMDHIRQLLEQHR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]