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The map label for this gene is glpD [H]

Identifier: 138895733

GI number: 138895733

Start: 2224743

End: 2226395

Strand: Reverse

Name: glpD [H]

Synonym: GTNG_2089

Alternate gene names: 138895733

Gene position: 2226395-2224743 (Counterclockwise)

Preceding gene: 138895734

Following gene: 138895732

Centisome position: 62.71

GC content: 52.33

Gene sequence:

>1653_bases
ATGGCTTTTTCAAGCAGACAGCGGAGTGAGTTGTTTAAAGCTATGAGTGAAAAAACGTATGATGTGCTTGTCATCGGCGG
GGGGATCACTGGTGGCGGTATCGCCCTTGATGCGGTTTCACGCGGCATGCAAACGGCGCTTGTTGAAATGCAAGATTTTG
CGGCTGGGACGTCGAGCCGCTCGACGAAGCTCGTTCACGGAGGTTTGCGCTATTTAAAACAGTTCGAAGTGAAAATGGTC
GCTGAAGTTGGGCGTGAACGAGCAGTCGTTTACGAAAACGGCCCGCACGTCACGACACCGGAGTGGATGTTGCTGCCGAT
TTATCGCGATGGGACGTTTGGCAAGTGGAGCACCTCTGTCGGCTTATGGCTGTATGACCGGCTAGCCGGCGTGAAGAAGA
GCGAGCGGCGGACGATGCTTAATGCTAAGCAGACGTTAGAAAAAGAACCGCTGTTAAAGAGCGACGGGCTCCTCGGCGGT
GGTTACTATGTCGAATACCGGACTGACGACGCTCGTTTGACGATCGAAGTGATCAAAAAGGCGGTCGAGCTTGGCGCCGA
CGCCGTCAACTATACGAAAGCAGAACAGTTTTTATATGACGACCGTGGTCGCATCATCGGCGCCCGCTGCCGTGACATGT
TAAGTGGACAGACATATGACATCCGTGCGAAAACAGTCGTCAATGCCGCCGGGCCATGGGTCGATACATTGCGTGACAAA
GACGGCTCGAAAACGAATAAGCGGCTCCAGTTAACAAAAGGTGTCCATCTTGTCATTGATCAAAAGCGGTTTCCGCTCAA
ACAGGCAATTTATTTTGATACGCCGGACGGCCGCATGGTATTTGCCATTCCTCGTGATGGAAAAACGTATGTCGGCACGA
CTGATACGTTTTATGACAGCGACCCTGCCCATCCGACGATGACGGAAGAAGACCGCGATTACTTATTGAAAGCAATCCGG
TATATGTTCCCATCGGTTGGCATCACGGCTGATGATGTCGAATCAAGTTGGGCTGGCGTCCGCCCGCTCATTTATGAAGA
AGGGAAAAACCCGTCGGAAATTTCCCGCAAAGACGAGATTTGGACATCGCCATCCGGCCTCATTACGATCGCCGGCGGCA
AGCTGACTGGCTACCGAAAAATGGCGGAAACGGTCGTCGATCTTGTCGCCAAGCAGCTTGAGAAAAAGGAACAAAAAACG
TTCCGGCCATGTCAAACGAAACAGTTGCCGATCTCCGGCGGCGATGTCGGCGGCTCACGCGAGTTGCCGGCATTCATCGC
CAAAAAAGCGGAAGAGGCGGTACGTTATGGATGGACGAAAGAAGAAGGGGCACGACTGGCAAAACAATACGGTACGAACG
TTGATCGGTTGTTTGCTTTAAGCAGGCAATACGATCGCTCATCTGGCTTAACGCGAGAAACGTTCGTCCGCCTCGTTTAC
GCGATTGAAGAAGAAATGGCTGTCAAACCCGTCGACTATTTCATCCGCCGCACCGGTTCGCTGTTGTTTGACATTGATTC
TGTCCGCCGGGAAAAAGAAGCAGTCATTGCGTTTATGGCCAGCTATTTACATTGGACAGAGGAGCAGACAGCAGTGTATA
CGAAGGAGCTGGAGCAAGCTCTCTGCCAAGCGGTGTTAGCAGTGGGGGGATGA

Upstream 100 bases:

>100_bases
GTCAGGAGACATGGAGAGACCATGCATACATGGTAGGCAGAACGCTTATCGTGTTTGTCATGGTCTCTTTTTGTCTTTTT
TGCACAGGAGGGACTAATCG

Downstream 100 bases:

>100_bases
CCGGAGGATCGTAAACAAATAGAAGAATTTTAGTGGGGACAGATGCTCGATAAAGAGGATCCATAGCACCTATCAGGCTC
GAATACGGGTACTTTTTTGC

Product: glycerol-3-phosphate dehydrogenase, aerobic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MAFSSRQRSELFKAMSEKTYDVLVIGGGITGGGIALDAVSRGMQTALVEMQDFAAGTSSRSTKLVHGGLRYLKQFEVKMV
AEVGRERAVVYENGPHVTTPEWMLLPIYRDGTFGKWSTSVGLWLYDRLAGVKKSERRTMLNAKQTLEKEPLLKSDGLLGG
GYYVEYRTDDARLTIEVIKKAVELGADAVNYTKAEQFLYDDRGRIIGARCRDMLSGQTYDIRAKTVVNAAGPWVDTLRDK
DGSKTNKRLQLTKGVHLVIDQKRFPLKQAIYFDTPDGRMVFAIPRDGKTYVGTTDTFYDSDPAHPTMTEEDRDYLLKAIR
YMFPSVGITADDVESSWAGVRPLIYEEGKNPSEISRKDEIWTSPSGLITIAGGKLTGYRKMAETVVDLVAKQLEKKEQKT
FRPCQTKQLPISGGDVGGSRELPAFIAKKAEEAVRYGWTKEEGARLAKQYGTNVDRLFALSRQYDRSSGLTRETFVRLVY
AIEEEMAVKPVDYFIRRTGSLLFDIDSVRREKEAVIAFMASYLHWTEEQTAVYTKELEQALCQAVLAVGG

Sequences:

>Translated_550_residues
MAFSSRQRSELFKAMSEKTYDVLVIGGGITGGGIALDAVSRGMQTALVEMQDFAAGTSSRSTKLVHGGLRYLKQFEVKMV
AEVGRERAVVYENGPHVTTPEWMLLPIYRDGTFGKWSTSVGLWLYDRLAGVKKSERRTMLNAKQTLEKEPLLKSDGLLGG
GYYVEYRTDDARLTIEVIKKAVELGADAVNYTKAEQFLYDDRGRIIGARCRDMLSGQTYDIRAKTVVNAAGPWVDTLRDK
DGSKTNKRLQLTKGVHLVIDQKRFPLKQAIYFDTPDGRMVFAIPRDGKTYVGTTDTFYDSDPAHPTMTEEDRDYLLKAIR
YMFPSVGITADDVESSWAGVRPLIYEEGKNPSEISRKDEIWTSPSGLITIAGGKLTGYRKMAETVVDLVAKQLEKKEQKT
FRPCQTKQLPISGGDVGGSRELPAFIAKKAEEAVRYGWTKEEGARLAKQYGTNVDRLFALSRQYDRSSGLTRETFVRLVY
AIEEEMAVKPVDYFIRRTGSLLFDIDSVRREKEAVIAFMASYLHWTEEQTAVYTKELEQALCQAVLAVGG
>Mature_549_residues
AFSSRQRSELFKAMSEKTYDVLVIGGGITGGGIALDAVSRGMQTALVEMQDFAAGTSSRSTKLVHGGLRYLKQFEVKMVA
EVGRERAVVYENGPHVTTPEWMLLPIYRDGTFGKWSTSVGLWLYDRLAGVKKSERRTMLNAKQTLEKEPLLKSDGLLGGG
YYVEYRTDDARLTIEVIKKAVELGADAVNYTKAEQFLYDDRGRIIGARCRDMLSGQTYDIRAKTVVNAAGPWVDTLRDKD
GSKTNKRLQLTKGVHLVIDQKRFPLKQAIYFDTPDGRMVFAIPRDGKTYVGTTDTFYDSDPAHPTMTEEDRDYLLKAIRY
MFPSVGITADDVESSWAGVRPLIYEEGKNPSEISRKDEIWTSPSGLITIAGGKLTGYRKMAETVVDLVAKQLEKKEQKTF
RPCQTKQLPISGGDVGGSRELPAFIAKKAEEAVRYGWTKEEGARLAKQYGTNVDRLFALSRQYDRSSGLTRETFVRLVYA
IEEEMAVKPVDYFIRRTGSLLFDIDSVRREKEAVIAFMASYLHWTEEQTAVYTKELEQALCQAVLAVGG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=550, Percent_Identity=34.3636363636364, Blast_Score=281, Evalue=2e-75,
Organism=Homo sapiens, GI285002231, Length=550, Percent_Identity=34.3636363636364, Blast_Score=281, Evalue=2e-75,
Organism=Escherichia coli, GI2367226, Length=470, Percent_Identity=31.2765957446809, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1788574, Length=396, Percent_Identity=25.7575757575758, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17509253, Length=468, Percent_Identity=36.5384615384615, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI115534726, Length=545, Percent_Identity=32.4770642201835, Blast_Score=245, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6322036, Length=580, Percent_Identity=31.2068965517241, Blast_Score=230, Evalue=3e-61,
Organism=Drosophila melanogaster, GI161077125, Length=542, Percent_Identity=34.3173431734317, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24653942, Length=542, Percent_Identity=34.3173431734317, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24653944, Length=542, Percent_Identity=34.3173431734317, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI20130025, Length=542, Percent_Identity=34.3173431734317, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24586295, Length=551, Percent_Identity=29.4010889292196, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI19921278, Length=551, Percent_Identity=27.5862068965517, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI45550977, Length=403, Percent_Identity=25.5583126550869, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61651; Mature: 61520

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSSRQRSELFKAMSEKTYDVLVIGGGITGGGIALDAVSRGMQTALVEMQDFAAGTSSR
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
STKLVHGGLRYLKQFEVKMVAEVGRERAVVYENGPHVTTPEWMLLPIYRDGTFGKWSTSV
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCH
GLWLYDRLAGVKKSERRTMLNAKQTLEKEPLLKSDGLLGGGYYVEYRTDDARLTIEVIKK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEEECCCCEEHHHHHHH
AVELGADAVNYTKAEQFLYDDRGRIIGARCRDMLSGQTYDIRAKTVVNAAGPWVDTLRDK
HHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEEEEHEEECCCCCHHHHHCCC
DGSKTNKRLQLTKGVHLVIDQKRFPLKQAIYFDTPDGRMVFAIPRDGKTYVGTTDTFYDS
CCCCCCCEEEEECCEEEEECCCCCCHHHEEEEECCCCEEEEEECCCCCEEECCCCCCCCC
DPAHPTMTEEDRDYLLKAIRYMFPSVGITADDVESSWAGVRPLIYEEGKNPSEISRKDEI
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEECCCCHHHCCCCCCC
WTSPSGLITIAGGKLTGYRKMAETVVDLVAKQLEKKEQKTFRPCQTKQLPISGGDVGGSR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
ELPAFIAKKAEEAVRYGWTKEEGARLAKQYGTNVDRLFALSRQYDRSSGLTRETFVRLVY
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
AIEEEMAVKPVDYFIRRTGSLLFDIDSVRREKEAVIAFMASYLHWTEEQTAVYTKELEQA
HHHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LCQAVLAVGG
HHHHHHHCCC
>Mature Secondary Structure 
AFSSRQRSELFKAMSEKTYDVLVIGGGITGGGIALDAVSRGMQTALVEMQDFAAGTSSR
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
STKLVHGGLRYLKQFEVKMVAEVGRERAVVYENGPHVTTPEWMLLPIYRDGTFGKWSTSV
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCH
GLWLYDRLAGVKKSERRTMLNAKQTLEKEPLLKSDGLLGGGYYVEYRTDDARLTIEVIKK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEEECCCCEEHHHHHHH
AVELGADAVNYTKAEQFLYDDRGRIIGARCRDMLSGQTYDIRAKTVVNAAGPWVDTLRDK
HHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEEEEHEEECCCCCHHHHHCCC
DGSKTNKRLQLTKGVHLVIDQKRFPLKQAIYFDTPDGRMVFAIPRDGKTYVGTTDTFYDS
CCCCCCCEEEEECCEEEEECCCCCCHHHEEEEECCCCEEEEEECCCCCEEECCCCCCCCC
DPAHPTMTEEDRDYLLKAIRYMFPSVGITADDVESSWAGVRPLIYEEGKNPSEISRKDEI
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEECCCCHHHCCCCCCC
WTSPSGLITIAGGKLTGYRKMAETVVDLVAKQLEKKEQKTFRPCQTKQLPISGGDVGGSR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
ELPAFIAKKAEEAVRYGWTKEEGARLAKQYGTNVDRLFALSRQYDRSSGLTRETFVRLVY
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
AIEEEMAVKPVDYFIRRTGSLLFDIDSVRREKEAVIAFMASYLHWTEEQTAVYTKELEQA
HHHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LCQAVLAVGG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]