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The map label for this gene is msmR [H]

Identifier: 138895727

GI number: 138895727

Start: 2216623

End: 2217645

Strand: Reverse

Name: msmR [H]

Synonym: GTNG_2083

Alternate gene names: 138895727

Gene position: 2217645-2216623 (Counterclockwise)

Preceding gene: 138895728

Following gene: 138895724

Centisome position: 62.46

GC content: 50.24

Gene sequence:

>1023_bases
ATGGCTACGCTAAAAGAAATTGCTGAAAAAGTCGGTGTCTCAGTCGCGACAGTGTCGCGCGTGCTCAATTATGATACAAC
ACTATCCGTCTCGGATGAGACGAGAAAGCGCATTTTTGAAGTTGCTCAAGAGCTGAACTACAAAACACTAAGGGAACGAA
GCCAGCAGGCGCGCGAATCGTTTCGCCTCGGGCTGATTCATTGGTATTCCGAACGTCAGGAAATCGATGACCCGTATTAT
ATGGCGATCCGTCTTGGAGTGGAAAAAGAATGTTTTGAACGTGGCATCCAACTTGTCAAATTGTTCAAACAGAACGGCGC
TTATCCGATTGAACGGATGAAGGAACTTGATGGTATCATCGCTGTCGGGAAATTCGGACCGAAAGAAGTGAGCGACTTTG
CTCGAGGAGCGAAGCAAATCGTGTTCGTCGACTGTTCACCTGATGAACGTCAGTTTGACTCGGTCGTCATCGACTTGCGC
CAAGCGACGATCACGGTGTTGGATTACTTGCTTCAGCTTGGGCACACGAAAATCGGGTATATCGGCGGCCGCGAATATGT
CGATGGGGAGACGCCGATCCGCGATGAGCGCGAAACAGCCTTTTACGAATACTTATACGTCAAAGGGATGTACGACTCGC
GTGATGTATGGATTGGCGCCTTTACTGCTGAAGATGGCTATCGGCTGATGAAAGAAGCGATTGCCAAAGGTGATTTGCCG
ACGGCGTTTTTTATCGCCAGCGATTCGATGGCAATCGGCGCTTTACGCGCGTTGCATGAGGCGGGGATTGCTGTTCCTCA
GGACGTAGCCATCGTCGGGTTCAATGATCTTCCGACTGCGGCATTTCTCCATCCCCCGCTTTCGACAGTGAAAGTGTATA
CTGAGTTTATGGGGGAAACAGCTGTTGAGCTACTCATCGAACGGTTGACGACAAAACGGACGATTTGCAAGAAAGTCATC
GTGCCGACCGAACTCGTCGTCCGTGCTAGCAGCGAGATCGATAAAAAGGGGAGCGGTCAATAA

Upstream 100 bases:

>100_bases
GCTTTCTCAGCTATGCAATTGCAAACATGTCGTCCTTTGTATAAATGCGGCGAAAAAACTCGTTTCATATGAAACATAAG
GAAGGGATCGCGAACAGACT

Downstream 100 bases:

>100_bases
GCCGCTCCCTTTTCATTAATGAAATTCGATGTCGACGCGCTTTTTCGTTCCTGCCGCTGTTTTTGGGATGTGAATATCGA
GCACACCGTTTTTGTATGTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MATLKEIAEKVGVSVATVSRVLNYDTTLSVSDETRKRIFEVAQELNYKTLRERSQQARESFRLGLIHWYSERQEIDDPYY
MAIRLGVEKECFERGIQLVKLFKQNGAYPIERMKELDGIIAVGKFGPKEVSDFARGAKQIVFVDCSPDERQFDSVVIDLR
QATITVLDYLLQLGHTKIGYIGGREYVDGETPIRDERETAFYEYLYVKGMYDSRDVWIGAFTAEDGYRLMKEAIAKGDLP
TAFFIASDSMAIGALRALHEAGIAVPQDVAIVGFNDLPTAAFLHPPLSTVKVYTEFMGETAVELLIERLTTKRTICKKVI
VPTELVVRASSEIDKKGSGQ

Sequences:

>Translated_340_residues
MATLKEIAEKVGVSVATVSRVLNYDTTLSVSDETRKRIFEVAQELNYKTLRERSQQARESFRLGLIHWYSERQEIDDPYY
MAIRLGVEKECFERGIQLVKLFKQNGAYPIERMKELDGIIAVGKFGPKEVSDFARGAKQIVFVDCSPDERQFDSVVIDLR
QATITVLDYLLQLGHTKIGYIGGREYVDGETPIRDERETAFYEYLYVKGMYDSRDVWIGAFTAEDGYRLMKEAIAKGDLP
TAFFIASDSMAIGALRALHEAGIAVPQDVAIVGFNDLPTAAFLHPPLSTVKVYTEFMGETAVELLIERLTTKRTICKKVI
VPTELVVRASSEIDKKGSGQ
>Mature_339_residues
ATLKEIAEKVGVSVATVSRVLNYDTTLSVSDETRKRIFEVAQELNYKTLRERSQQARESFRLGLIHWYSERQEIDDPYYM
AIRLGVEKECFERGIQLVKLFKQNGAYPIERMKELDGIIAVGKFGPKEVSDFARGAKQIVFVDCSPDERQFDSVVIDLRQ
ATITVLDYLLQLGHTKIGYIGGREYVDGETPIRDERETAFYEYLYVKGMYDSRDVWIGAFTAEDGYRLMKEAIAKGDLPT
AFFIASDSMAIGALRALHEAGIAVPQDVAIVGFNDLPTAAFLHPPLSTVKVYTEFMGETAVELLIERLTTKRTICKKVIV
PTELVVRASSEIDKKGSGQ

Specific function: Repressor For Beta Galactosidase Alpha And Beta Subunits (Ebga And Ebgc). Binds Lactose As An Inducer. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789456, Length=333, Percent_Identity=41.1411411411411, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787948, Length=347, Percent_Identity=30.835734870317, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790194, Length=325, Percent_Identity=29.8461538461538, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790369, Length=339, Percent_Identity=29.7935103244838, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789068, Length=310, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786540, Length=346, Percent_Identity=26.0115606936416, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788474, Length=317, Percent_Identity=26.4984227129338, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789202, Length=304, Percent_Identity=27.6315789473684, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787580, Length=340, Percent_Identity=25.8823529411765, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790715, Length=321, Percent_Identity=25.5451713395639, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787906, Length=349, Percent_Identity=23.2091690544413, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38294; Mature: 38163

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLKEIAEKVGVSVATVSRVLNYDTTLSVSDETRKRIFEVAQELNYKTLRERSQQARES
CCCHHHHHHHHCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FRLGLIHWYSERQEIDDPYYMAIRLGVEKECFERGIQLVKLFKQNGAYPIERMKELDGII
HHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEE
AVGKFGPKEVSDFARGAKQIVFVDCSPDERQFDSVVIDLRQATITVLDYLLQLGHTKIGY
EECCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
IGGREYVDGETPIRDERETAFYEYLYVKGMYDSRDVWIGAFTAEDGYRLMKEAIAKGDLP
CCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCEEEEEEECCCHHHHHHHHHHCCCCC
TAFFIASDSMAIGALRALHEAGIAVPQDVAIVGFNDLPTAAFLHPPLSTVKVYTEFMGET
EEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHH
AVELLIERLTTKRTICKKVIVPTELVVRASSEIDKKGSGQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCCCCCC
>Mature Secondary Structure 
ATLKEIAEKVGVSVATVSRVLNYDTTLSVSDETRKRIFEVAQELNYKTLRERSQQARES
CCHHHHHHHHCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FRLGLIHWYSERQEIDDPYYMAIRLGVEKECFERGIQLVKLFKQNGAYPIERMKELDGII
HHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEE
AVGKFGPKEVSDFARGAKQIVFVDCSPDERQFDSVVIDLRQATITVLDYLLQLGHTKIGY
EECCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
IGGREYVDGETPIRDERETAFYEYLYVKGMYDSRDVWIGAFTAEDGYRLMKEAIAKGDLP
CCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCEEEEEEECCCHHHHHHHHHHCCCCC
TAFFIASDSMAIGALRALHEAGIAVPQDVAIVGFNDLPTAAFLHPPLSTVKVYTEFMGET
EEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHH
AVELLIERLTTKRTICKKVIVPTELVVRASSEIDKKGSGQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]