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The map label for this gene is ycgO [H]

Identifier: 138895676

GI number: 138895676

Start: 2149880

End: 2151316

Strand: Reverse

Name: ycgO [H]

Synonym: GTNG_2032

Alternate gene names: 138895676

Gene position: 2151316-2149880 (Counterclockwise)

Preceding gene: 138895678

Following gene: 138895675

Centisome position: 60.6

GC content: 51.57

Gene sequence:

>1437_bases
ATGAATGGCATCATCTTGGCGGAACTCGTGCTGTATTGTCTTGTGTTGGCCGCTCTTGGTTATTGGTATGGAAAAAAAGA
GATGAGTCATAGTGATTTTTTGCTTGGCGGAAAAAAGCTTCCGGGTTGGACGCTTGCTTTTTCCGAACGGGCGACAGGGG
AATCGGCGTGGCTGTTGCTTGGCTATACGGGTTTTGTGTTTGCGAGCGGACTTTCTGCGATTTGGGTGGCAGTAGGCATT
GTCATCGGCATTGTCAGTGCTTGGCTTTTTTTGGCTGACCGGTTTCGCCAAGAGGCGGAGCGGTACGGGGTGTTGACACT
GCCAAGCTATTTGGCGCAACGGTTTGGTCAGCAAGGGCGCACGATTTTATGGCTTTCTACTGTTTTGATTTTTAGTTTTA
TGATGTTCTATTTTAGCGCTCAAATCGCAGGCGCCGGCAAAACGCTGTTTACTGTTTTTCATATCGATCCAGCACTTGGC
ATGGTCATCAGTGTGGCGATTGTCATCATCTTGTCATACACTGGCGGGTTTGTCAGTGTCGTTTGGACAGATATGATTCA
AAGTGTGCTCATGCTGGCAACGCTCGTTATTTTGCCAATTGTGGCGTTAGTGGAAATTTATAGCGGCGGATTGTCGATCA
GTGAAGCGCTTCATCATGCGAAACCAGGCCTCGACTCATGGACAGGGGGAGTGACTGGTTTTGCGCTTGGGCTATTGTTG
TTTAACAATTTTGCTTGGTTTTTCGGCTACCTTGGTGGACAGCCGCAATTGAGCGCCCGTTTCATGGCATTAAAAGATGC
CCGCGAGGCGAAAACGGCCAAAACGGTGGCGGTCGTTTGGACACTATTGGCGTATGGTGGGGCGTTTCTCATCGGTCTGA
CAGCGATTACCCTTTACCAAGGACATTCCTTCGCCGATGTCGAGACCGTGTTGCCGCATATGGTGTTGGACTTGTTGCCG
CCGTGGTTGGCCGGGTTGCTGTTATCCGGCATTTTGGCCGCCATCGTGACAACGGCCGATTCACAGCTGCTTGTGATCAC
AGGCGCCATTAGCGAAGACATCGTACGCCGTTCTTTGCGTCTCCGTTTGTCGGAGAAACAGCTTGTCACTTTATCACGTA
CGGTTGTCGTAGCCGGCGGATTGCTTGGTCTTGTATTGGCGATGACATCGGAGTCGCTCGTGTATCTCGTTGTCAGCTGG
GCGTGGGCGGGAATCGGTTGCACGTTGTCACCGGCGATTTTACTCGCCTTTTTCTGGAAGCGGTATTCCGGCATCGGTGT
CATCGCCACGATCCTCGCTGGGTTTATCAGCACAATCATCTGGATTTCCTCGCCGCTTGAGGACATCATCAGTTCACGGT
TTACGACGTTTGCCATTGCGCTAGTGGCCGGGGTGTTGTTCAGCTTGTTGTTTCCTGACCGCCAGCGGACGACGTGA

Upstream 100 bases:

>100_bases
CTTTGTTCGATGGCAATGCCGGTTTTTTATGGGAAAATGGCGCAACAGTAGAGAGGGAGGCAGTGTGGTGAGGTGAACTA
TATAGCGAGGGGGAGAAACA

Downstream 100 bases:

>100_bases
CCAACAACACTGGTCATCACCAGTATAAGGGTGTCCCGAAAGCAGCGGGACGCCCTTTCCCATGGCGAAGCGTGCCCCCA
TTGCCTGCTGCCCCACCGTA

Product: proline or pantothenate permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MNGIILAELVLYCLVLAALGYWYGKKEMSHSDFLLGGKKLPGWTLAFSERATGESAWLLLGYTGFVFASGLSAIWVAVGI
VIGIVSAWLFLADRFRQEAERYGVLTLPSYLAQRFGQQGRTILWLSTVLIFSFMMFYFSAQIAGAGKTLFTVFHIDPALG
MVISVAIVIILSYTGGFVSVVWTDMIQSVLMLATLVILPIVALVEIYSGGLSISEALHHAKPGLDSWTGGVTGFALGLLL
FNNFAWFFGYLGGQPQLSARFMALKDAREAKTAKTVAVVWTLLAYGGAFLIGLTAITLYQGHSFADVETVLPHMVLDLLP
PWLAGLLLSGILAAIVTTADSQLLVITGAISEDIVRRSLRLRLSEKQLVTLSRTVVVAGGLLGLVLAMTSESLVYLVVSW
AWAGIGCTLSPAILLAFFWKRYSGIGVIATILAGFISTIIWISSPLEDIISSRFTTFAIALVAGVLFSLLFPDRQRTT

Sequences:

>Translated_478_residues
MNGIILAELVLYCLVLAALGYWYGKKEMSHSDFLLGGKKLPGWTLAFSERATGESAWLLLGYTGFVFASGLSAIWVAVGI
VIGIVSAWLFLADRFRQEAERYGVLTLPSYLAQRFGQQGRTILWLSTVLIFSFMMFYFSAQIAGAGKTLFTVFHIDPALG
MVISVAIVIILSYTGGFVSVVWTDMIQSVLMLATLVILPIVALVEIYSGGLSISEALHHAKPGLDSWTGGVTGFALGLLL
FNNFAWFFGYLGGQPQLSARFMALKDAREAKTAKTVAVVWTLLAYGGAFLIGLTAITLYQGHSFADVETVLPHMVLDLLP
PWLAGLLLSGILAAIVTTADSQLLVITGAISEDIVRRSLRLRLSEKQLVTLSRTVVVAGGLLGLVLAMTSESLVYLVVSW
AWAGIGCTLSPAILLAFFWKRYSGIGVIATILAGFISTIIWISSPLEDIISSRFTTFAIALVAGVLFSLLFPDRQRTT
>Mature_478_residues
MNGIILAELVLYCLVLAALGYWYGKKEMSHSDFLLGGKKLPGWTLAFSERATGESAWLLLGYTGFVFASGLSAIWVAVGI
VIGIVSAWLFLADRFRQEAERYGVLTLPSYLAQRFGQQGRTILWLSTVLIFSFMMFYFSAQIAGAGKTLFTVFHIDPALG
MVISVAIVIILSYTGGFVSVVWTDMIQSVLMLATLVILPIVALVEIYSGGLSISEALHHAKPGLDSWTGGVTGFALGLLL
FNNFAWFFGYLGGQPQLSARFMALKDAREAKTAKTVAVVWTLLAYGGAFLIGLTAITLYQGHSFADVETVLPHMVLDLLP
PWLAGLLLSGILAAIVTTADSQLLVITGAISEDIVRRSLRLRLSEKQLVTLSRTVVVAGGLLGLVLAMTSESLVYLVVSW
AWAGIGCTLSPAILLAFFWKRYSGIGVIATILAGFISTIIWISSPLEDIISSRFTTFAIALVAGVLFSLLFPDRQRTT

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=442, Percent_Identity=32.3529411764706, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI14140236, Length=471, Percent_Identity=25.0530785562633, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI109659836, Length=477, Percent_Identity=22.8511530398323, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI109659839, Length=493, Percent_Identity=22.5152129817444, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI167466278, Length=398, Percent_Identity=25.1256281407035, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4507035, Length=381, Percent_Identity=22.8346456692913, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4507031, Length=489, Percent_Identity=24.7443762781186, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787251, Length=444, Percent_Identity=30.4054054054054, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1790503, Length=438, Percent_Identity=23.5159817351598, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082237, Length=441, Percent_Identity=24.0362811791383, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790113, Length=399, Percent_Identity=24.5614035087719, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17539284, Length=473, Percent_Identity=23.6786469344609, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24648033, Length=431, Percent_Identity=23.4338747099768, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356865, Length=431, Percent_Identity=23.4338747099768, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24645928, Length=380, Percent_Identity=22.1052631578947, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640370, Length=368, Percent_Identity=22.2826086956522, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 51692; Mature: 51692

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGIILAELVLYCLVLAALGYWYGKKEMSHSDFLLGGKKLPGWTLAFSERATGESAWLLL
CCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEECCCCCCCCEEEEE
GYTGFVFASGLSAIWVAVGIVIGIVSAWLFLADRFRQEAERYGVLTLPSYLAQRFGQQGR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCC
TILWLSTVLIFSFMMFYFSAQIAGAGKTLFTVFHIDPALGMVISVAIVIILSYTGGFVSV
EEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHH
VWTDMIQSVLMLATLVILPIVALVEIYSGGLSISEALHHAKPGLDSWTGGVTGFALGLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
FNNFAWFFGYLGGQPQLSARFMALKDAREAKTAKTVAVVWTLLAYGGAFLIGLTAITLYQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GHSFADVETVLPHMVLDLLPPWLAGLLLSGILAAIVTTADSQLLVITGAISEDIVRRSLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
LRLSEKQLVTLSRTVVVAGGLLGLVLAMTSESLVYLVVSWAWAGIGCTLSPAILLAFFWK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RYSGIGVIATILAGFISTIIWISSPLEDIISSRFTTFAIALVAGVLFSLLFPDRQRTT
HHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNGIILAELVLYCLVLAALGYWYGKKEMSHSDFLLGGKKLPGWTLAFSERATGESAWLLL
CCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEECCCCCCCCEEEEE
GYTGFVFASGLSAIWVAVGIVIGIVSAWLFLADRFRQEAERYGVLTLPSYLAQRFGQQGR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCC
TILWLSTVLIFSFMMFYFSAQIAGAGKTLFTVFHIDPALGMVISVAIVIILSYTGGFVSV
EEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHH
VWTDMIQSVLMLATLVILPIVALVEIYSGGLSISEALHHAKPGLDSWTGGVTGFALGLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
FNNFAWFFGYLGGQPQLSARFMALKDAREAKTAKTVAVVWTLLAYGGAFLIGLTAITLYQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GHSFADVETVLPHMVLDLLPPWLAGLLLSGILAAIVTTADSQLLVITGAISEDIVRRSLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
LRLSEKQLVTLSRTVVVAGGLLGLVLAMTSESLVYLVVSWAWAGIGCTLSPAILLAFFWK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RYSGIGVIATILAGFISTIIWISSPLEDIISSRFTTFAIALVAGVLFSLLFPDRQRTT
HHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]