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The map label for this gene is gltA [H]

Identifier: 138895599

GI number: 138895599

Start: 2076255

End: 2077097

Strand: Reverse

Name: gltA [H]

Synonym: GTNG_1952

Alternate gene names: 138895599

Gene position: 2077097-2076255 (Counterclockwise)

Preceding gene: 138895600

Following gene: 138895598

Centisome position: 58.5

GC content: 55.52

Gene sequence:

>843_bases
ATGAAACAACGAAGCGCCCTCGATATGTATGCTGACGGAGCGGCATGGTGGGAGACATCGATCAGCGATGTCCGCAAAAA
TGAAATTCTCGTTCGAGGTTATCCAATCGAAGAACTGATTGGTAACATCTCGTATACGCAAATGCTTTATCTCCTATTAT
GCGGCGAGATATTGAGCGAGAAAAAAGCGAAGTTATGGGAAAGCGTCCTCGTCGCTGGGGCGGACCATGGCCCGCGCGCG
CCATCGATTGCGGCAGCCCGCATGGCGGCGACATGCGGTATTTCCTTCAACTCGTGCATCGCCACCGGCATTAACGTGCT
TGGCGATGTACACGGGGGAGCGGTGGAGAAAGCGATGGCGCTATTTTATGAAACGAACGGGCAGATTGAAGCTCGCGGTG
GAGACGACGCGATCAGCACCGTGGTCAGTGAATGGTTTGAACAGTTTCGGCGCGAAGGGCGGAAGCTGCCTGGATTTGGC
CACCAGCTTCATGACGATGATCCGCGCGTCAAGCGGCTGTACGCGTTGGCTGAGCAGCTTATGGAAGAGGGAGAGATCAG
CGGGCGGTATTTAACGATCGCAGAAACGTATCGCTCCCAGCTCGAGAAGGCGAAAGGGAAAAAAATGACGATGAATATCG
ACGGGGTGGCGGCCGCGATCCAGTGTGAGCTCGGCGTGCCGGCTGCAGCGGCGAAAGGTGTGTTTGCTTTGTCGCGGGGA
ATGGGCATTGTCGCTCACGCATTTGAAGAATGGCAAAACGGGGTGTTGATCAAAGGGCCGTGCCCGAACCGCAGCGATTT
GGTCCGCTACACCGGGCCGGAGAGACGTCATTTTGAAAAGTAG

Upstream 100 bases:

>100_bases
CTATTTTTTAGATCGATCTAATACGAATTTGAAACTTTTATTAGATCGATCTAATTAATTGGCGGCTTGATCAACGCTCA
GAAGGAGGGATAGCCTAGCC

Downstream 100 bases:

>100_bases
GTGATAAACGTGCGAAAGGCACAACTGTACATTAATGGAACATGGGTGGAAGATAACCGTGCAGTGAAGCCGGTGAAAAA
CCCGTATACCGGAGAAGTGA

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKQRSALDMYADGAAWWETSISDVRKNEILVRGYPIEELIGNISYTQMLYLLLCGEILSEKKAKLWESVLVAGADHGPRA
PSIAAARMAATCGISFNSCIATGINVLGDVHGGAVEKAMALFYETNGQIEARGGDDAISTVVSEWFEQFRREGRKLPGFG
HQLHDDDPRVKRLYALAEQLMEEGEISGRYLTIAETYRSQLEKAKGKKMTMNIDGVAAAIQCELGVPAAAAKGVFALSRG
MGIVAHAFEEWQNGVLIKGPCPNRSDLVRYTGPERRHFEK

Sequences:

>Translated_280_residues
MKQRSALDMYADGAAWWETSISDVRKNEILVRGYPIEELIGNISYTQMLYLLLCGEILSEKKAKLWESVLVAGADHGPRA
PSIAAARMAATCGISFNSCIATGINVLGDVHGGAVEKAMALFYETNGQIEARGGDDAISTVVSEWFEQFRREGRKLPGFG
HQLHDDDPRVKRLYALAEQLMEEGEISGRYLTIAETYRSQLEKAKGKKMTMNIDGVAAAIQCELGVPAAAAKGVFALSRG
MGIVAHAFEEWQNGVLIKGPCPNRSDLVRYTGPERRHFEK
>Mature_280_residues
MKQRSALDMYADGAAWWETSISDVRKNEILVRGYPIEELIGNISYTQMLYLLLCGEILSEKKAKLWESVLVAGADHGPRA
PSIAAARMAATCGISFNSCIATGINVLGDVHGGAVEKAMALFYETNGQIEARGGDDAISTVVSEWFEQFRREGRKLPGFG
HQLHDDDPRVKRLYALAEQLMEEGEISGRYLTIAETYRSQLEKAKGKKMTMNIDGVAAAIQCELGVPAAAAKGVFALSRG
MGIVAHAFEEWQNGVLIKGPCPNRSDLVRYTGPERRHFEK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38569423, Length=279, Percent_Identity=23.2974910394265, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38569421, Length=279, Percent_Identity=23.2974910394265, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786939, Length=258, Percent_Identity=26.3565891472868, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551266, Length=278, Percent_Identity=24.4604316546763, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17557344, Length=279, Percent_Identity=24.7311827956989, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363477, Length=282, Percent_Identity=23.0496453900709, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI281363475, Length=282, Percent_Identity=23.0496453900709, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI281363473, Length=282, Percent_Identity=23.0496453900709, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 30755; Mature: 30755

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRSALDMYADGAAWWETSISDVRKNEILVRGYPIEELIGNISYTQMLYLLLCGEILSE
CCCCCCHHHHCCCHHHHHHHHHHHHHCCEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHH
KKAKLWESVLVAGADHGPRAPSIAAARMAATCGISFNSCIATGINVLGDVHGGAVEKAMA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
LFYETNGQIEARGGDDAISTVVSEWFEQFRREGRKLPGFGHQLHDDDPRVKRLYALAEQL
HHEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MEEGEISGRYLTIAETYRSQLEKAKGKKMTMNIDGVAAAIQCELGVPAAAAKGVFALSRG
HHCCCCCCCEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHC
MGIVAHAFEEWQNGVLIKGPCPNRSDLVRYTGPERRHFEK
CHHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MKQRSALDMYADGAAWWETSISDVRKNEILVRGYPIEELIGNISYTQMLYLLLCGEILSE
CCCCCCHHHHCCCHHHHHHHHHHHHHCCEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHH
KKAKLWESVLVAGADHGPRAPSIAAARMAATCGISFNSCIATGINVLGDVHGGAVEKAMA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
LFYETNGQIEARGGDDAISTVVSEWFEQFRREGRKLPGFGHQLHDDDPRVKRLYALAEQL
HHEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MEEGEISGRYLTIAETYRSQLEKAKGKKMTMNIDGVAAAIQCELGVPAAAAKGVFALSRG
HHCCCCCCCEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHC
MGIVAHAFEEWQNGVLIKGPCPNRSDLVRYTGPERRHFEK
CHHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3442626 [H]