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The map label for this gene is pdh [H]

Identifier: 138895563

GI number: 138895563

Start: 2039548

End: 2040690

Strand: Reverse

Name: pdh [H]

Synonym: GTNG_1916

Alternate gene names: 138895563

Gene position: 2040690-2039548 (Counterclockwise)

Preceding gene: 138895564

Following gene: 138895562

Centisome position: 57.48

GC content: 51.09

Gene sequence:

>1143_bases
ATGAATGTCATGTTGTCATCAGAAAGGGCACAGAGCTTCGACTTATTTGAACAAATGCGTGAGCATGAACAAATTGTGTT
TTGCCATGATGAAGCGACCGGGCTGAACGCGATCATCGCCATTCATAGCACGGCGCTTGGACCGGCGCTTGGCGGCTGTC
GGATGTATCCGTATGCGACAACGGAAGAGGCGTTAGCGGATGTGCTTCGACTGTCCAAAGGGATGACGTATAAATGCTTG
GCTGCCGATGTCGACTTTGGCGGCGGCAAAGCGGTAATCATCGGTGATCCGCGCAAAGACAAATCACCGGAATTGTTTCG
AGCTTTCGGTCAATTCGTTGAGTCGCTAGGTGGGCGCTTTTACACCGGCACTGATATGGGGACGACACCGGATGATTTCG
TGCATGCGCTGAAGGAGACAAACTGCATTGTTGGCGTCCCCGAAGCGTATGGAGGAAGCGGCGACTCATCGGTGCCGACT
GCTGCCGGTGTCATTTACGGTATCCAAGCGACGAACTATGTTGCGTTTGGCAACAAAAATTTGCACGGAAAAACATACGC
GGTGCAAGGGCTTGGGAAAGTGGGAAAAAAAGTGGCGTTTCGCTTACTTGAAGAAGGGGCTGATCTGTATGTATGCGATT
TGAACGAAGCAGCGGTTGAAGAGGTGGTGGCGTATGGGAAACAAATCGGAGCGTTAGTAAAACCTGTCAATGGGACGGAG
ATTTATCGCGTCAATGCTGATGTGTTTGTCCCGTGTGCATTTGGCGGTGTCATAAACGATGAAACAGCCGCCAGCCTGCG
GGTAAAAGCGGTCGTCGGGTCAGCGAACAACCAGTTGGTCGACAAACGCCATGCCCGTATGTTGAAAGAAAGAGGCATTG
TATATGCTCCCGATTACATTGTCAACGCCGGCGGGCTGATTCAGGTGGCCGATGAACTGTACGGAGCGAACAAAGAGCGA
GTGTTGGCGAAAACGAAAGCGATTTATGATACACTGCTCGCCATTTATACACGAGCTGAATCGGAAGGGATAACGACGAT
GGACGCCGCCGATCAATTTTGTGAAGAGCGGCTCGAAAAGCGTAAACAACGCAATCATTTCTTTGCGCATCAAAAACGGC
CGAAGTGGGATATCCGTCGTTAG

Upstream 100 bases:

>100_bases
ACTATTGAAATAGTATAACGATTTTATAACGTTTGTATATTTTTTGTTATATTAACTTGAAAACGCTTTCAAGCGGTAAA
GCAAAGGGGAGAGGGAAGCG

Downstream 100 bases:

>100_bases
GAGAGGAGAAAACGGATCGGAAAGAGTCGCTTTCATACCTAAAAATGAACGAATTTTCATGCAGATACACCAGGGGTATG
CCCACTTTTTATAGAGATCT

Product: L-phenylalanine dehydrogenase

Products: NA

Alternate protein names: PheDH [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNVMLSSERAQSFDLFEQMREHEQIVFCHDEATGLNAIIAIHSTALGPALGGCRMYPYATTEEALADVLRLSKGMTYKCL
AADVDFGGGKAVIIGDPRKDKSPELFRAFGQFVESLGGRFYTGTDMGTTPDDFVHALKETNCIVGVPEAYGGSGDSSVPT
AAGVIYGIQATNYVAFGNKNLHGKTYAVQGLGKVGKKVAFRLLEEGADLYVCDLNEAAVEEVVAYGKQIGALVKPVNGTE
IYRVNADVFVPCAFGGVINDETAASLRVKAVVGSANNQLVDKRHARMLKERGIVYAPDYIVNAGGLIQVADELYGANKER
VLAKTKAIYDTLLAIYTRAESEGITTMDAADQFCEERLEKRKQRNHFFAHQKRPKWDIRR

Sequences:

>Translated_380_residues
MNVMLSSERAQSFDLFEQMREHEQIVFCHDEATGLNAIIAIHSTALGPALGGCRMYPYATTEEALADVLRLSKGMTYKCL
AADVDFGGGKAVIIGDPRKDKSPELFRAFGQFVESLGGRFYTGTDMGTTPDDFVHALKETNCIVGVPEAYGGSGDSSVPT
AAGVIYGIQATNYVAFGNKNLHGKTYAVQGLGKVGKKVAFRLLEEGADLYVCDLNEAAVEEVVAYGKQIGALVKPVNGTE
IYRVNADVFVPCAFGGVINDETAASLRVKAVVGSANNQLVDKRHARMLKERGIVYAPDYIVNAGGLIQVADELYGANKER
VLAKTKAIYDTLLAIYTRAESEGITTMDAADQFCEERLEKRKQRNHFFAHQKRPKWDIRR
>Mature_380_residues
MNVMLSSERAQSFDLFEQMREHEQIVFCHDEATGLNAIIAIHSTALGPALGGCRMYPYATTEEALADVLRLSKGMTYKCL
AADVDFGGGKAVIIGDPRKDKSPELFRAFGQFVESLGGRFYTGTDMGTTPDDFVHALKETNCIVGVPEAYGGSGDSSVPT
AAGVIYGIQATNYVAFGNKNLHGKTYAVQGLGKVGKKVAFRLLEEGADLYVCDLNEAAVEEVVAYGKQIGALVKPVNGTE
IYRVNADVFVPCAFGGVINDETAASLRVKAVVGSANNQLVDKRHARMLKERGIVYAPDYIVNAGGLIQVADELYGANKER
VLAKTKAIYDTLLAIYTRAESEGITTMDAADQFCEERLEKRKQRNHFFAHQKRPKWDIRR

Specific function: Unknown

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

Organism=Homo sapiens, GI31377775, Length=305, Percent_Identity=24.9180327868852, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4885281, Length=305, Percent_Identity=25.2459016393443, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544676, Length=312, Percent_Identity=25.6410256410256, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45549226, Length=308, Percent_Identity=28.2467532467532, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI45553475, Length=308, Percent_Identity=28.2467532467532, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24649460, Length=273, Percent_Identity=27.4725274725275, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 9362 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR016211
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.20 [H]

Molecular weight: Translated: 41456; Mature: 41456

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00074 GLFV_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVMLSSERAQSFDLFEQMREHEQIVFCHDEATGLNAIIAIHSTALGPALGGCRMYPYAT
CCCEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECHHCCCCCCCCEECCCCC
TEEALADVLRLSKGMTYKCLAADVDFGGGKAVIIGDPRKDKSPELFRAFGQFVESLGGRF
HHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCEE
YTGTDMGTTPDDFVHALKETNCIVGVPEAYGGSGDSSVPTAAGVIYGIQATNYVAFGNKN
EECCCCCCCHHHHHHHHHHCCCEEECCHHCCCCCCCCCCCHHHEEEEEEECCEEEECCCC
LHGKTYAVQGLGKVGKKVAFRLLEEGADLYVCDLNEAAVEEVVAYGKQIGALVKPVNGTE
CCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCE
IYRVNADVFVPCAFGGVINDETAASLRVKAVVGSANNQLVDKRHARMLKERGIVYAPDYI
EEEECCCEEEEEECCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCE
VNAGGLIQVADELYGANKERVLAKTKAIYDTLLAIYTRAESEGITTMDAADQFCEERLEK
ECCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
RKQRNHFFAHQKRPKWDIRR
HHHHCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MNVMLSSERAQSFDLFEQMREHEQIVFCHDEATGLNAIIAIHSTALGPALGGCRMYPYAT
CCCEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECHHCCCCCCCCEECCCCC
TEEALADVLRLSKGMTYKCLAADVDFGGGKAVIIGDPRKDKSPELFRAFGQFVESLGGRF
HHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCEE
YTGTDMGTTPDDFVHALKETNCIVGVPEAYGGSGDSSVPTAAGVIYGIQATNYVAFGNKN
EECCCCCCCHHHHHHHHHHCCCEEECCHHCCCCCCCCCCCHHHEEEEEEECCEEEECCCC
LHGKTYAVQGLGKVGKKVAFRLLEEGADLYVCDLNEAAVEEVVAYGKQIGALVKPVNGTE
CCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCE
IYRVNADVFVPCAFGGVINDETAASLRVKAVVGSANNQLVDKRHARMLKERGIVYAPDYI
EEEECCCEEEEEECCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCE
VNAGGLIQVADELYGANKERVLAKTKAIYDTLLAIYTRAESEGITTMDAADQFCEERLEK
ECCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
RKQRNHFFAHQKRPKWDIRR
HHHHCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535000 [H]