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The map label for this gene is yjhH [H]

Identifier: 138895513

GI number: 138895513

Start: 1984948

End: 1985892

Strand: Reverse

Name: yjhH [H]

Synonym: GTNG_1861

Alternate gene names: 138895513

Gene position: 1985892-1984948 (Counterclockwise)

Preceding gene: 138895514

Following gene: 138895512

Centisome position: 55.94

GC content: 43.39

Gene sequence:

>945_bases
ATGGCTTGCAAGTGGAAAGGTATTATTCCCCCAGTTGTCACTTTATTCGATGAGAAGCGTGGGTTTGATTGGGAAGCCAA
CTATTTTCTTGCTGATTATTTGATTCAACAGGGAGTTCATGGGCTGCTCTATATGGGGAGCACAGGAGAGTTTTCCTCCT
TAACATCCGAGGAGAGAAAAGTTTTCGCCGAAAGAATGGTACGATACGTAGATGGGCGTGTTCCGGTTTTGATTGGCACG
GGTTCAACTTCATTAAAGGAGACGATATATTTATCACAACATGCTGAATCAATAGGGGCGAGCGGGGTGCTTGTTGTCAA
CCCATTTTACTGGAAATATACAGATCGTCAACTGTATGACTACTATACAAGTGTGGCGAAGAGCATTCGCATTCCGTTGT
TGATTTATAATATCCCTTTGCTCACTGGACAGGATTTGTCTCCTGATCTTGTGTTAAGGTTGGCGGTCGAGCACGAGAAT
ATTGTAGGAATCAAAGATACAACGGAGAAGCTGGGGCATATTCGGCAATTGATCCGTATTAAAGAACAAAGAGAAGATTT
CGCCGTGTTTGCTGCTTTCGATGACCTTCTTCTTCCGTCCTTGCAAATGGGAGCTGCTGGTGCTATTAATGGCACAGCTG
TTTTTCTGCCGGAGCTGTCGGTTCAGTTGTTTGAGAGTTTTCATGCCCAACAATATGAGGAGACGTTAAAGGCCAATGAA
TCAATCTTGAAGCTTATGGCAATTTACGAGCTTTCCCAACCGTTATATATCGCCATTAAAGAAGCGGTTCATCAGCTTAT
TCTTGGCCGACATACGGCGTTGCGGCCGCCTGTGAAGGAATGTGATGAGTTGGAAGATCGCATCCGAATATTTCTGAATA
AAAATAACATTCAATCATATAGAGAGGCAAGGAATCGCCTTGTTTTTCCGAAAAACAGAAAATGA

Upstream 100 bases:

>100_bases
TGGCAAAAGACATTCATTGGAATGTTTTCTTTTGCTTCCGCTTTAGCCTTTCCTGTTATATTGGGGAAGATGCAGCCAAA
TGATGAGAGGGTGAGAGAGG

Downstream 100 bases:

>100_bases
AAGGGTGTTAAAAACATGTTTATGAAAGAAACGAGGGAGTTTCTCGAATCGCTAGGCTATCCGTCGGGAGATTGCTATGA
TCTCCCCACTTCTTCCAAAC

Product: putative lyase/synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MACKWKGIIPPVVTLFDEKRGFDWEANYFLADYLIQQGVHGLLYMGSTGEFSSLTSEERKVFAERMVRYVDGRVPVLIGT
GSTSLKETIYLSQHAESIGASGVLVVNPFYWKYTDRQLYDYYTSVAKSIRIPLLIYNIPLLTGQDLSPDLVLRLAVEHEN
IVGIKDTTEKLGHIRQLIRIKEQREDFAVFAAFDDLLLPSLQMGAAGAINGTAVFLPELSVQLFESFHAQQYEETLKANE
SILKLMAIYELSQPLYIAIKEAVHQLILGRHTALRPPVKECDELEDRIRIFLNKNNIQSYREARNRLVFPKNRK

Sequences:

>Translated_314_residues
MACKWKGIIPPVVTLFDEKRGFDWEANYFLADYLIQQGVHGLLYMGSTGEFSSLTSEERKVFAERMVRYVDGRVPVLIGT
GSTSLKETIYLSQHAESIGASGVLVVNPFYWKYTDRQLYDYYTSVAKSIRIPLLIYNIPLLTGQDLSPDLVLRLAVEHEN
IVGIKDTTEKLGHIRQLIRIKEQREDFAVFAAFDDLLLPSLQMGAAGAINGTAVFLPELSVQLFESFHAQQYEETLKANE
SILKLMAIYELSQPLYIAIKEAVHQLILGRHTALRPPVKECDELEDRIRIFLNKNNIQSYREARNRLVFPKNRK
>Mature_313_residues
ACKWKGIIPPVVTLFDEKRGFDWEANYFLADYLIQQGVHGLLYMGSTGEFSSLTSEERKVFAERMVRYVDGRVPVLIGTG
STSLKETIYLSQHAESIGASGVLVVNPFYWKYTDRQLYDYYTSVAKSIRIPLLIYNIPLLTGQDLSPDLVLRLAVEHENI
VGIKDTTEKLGHIRQLIRIKEQREDFAVFAAFDDLLLPSLQMGAAGAINGTAVFLPELSVQLFESFHAQQYEETLKANES
ILKLMAIYELSQPLYIAIKEAVHQLILGRHTALRPPVKECDELEDRIRIFLNKNNIQSYREARNRLVFPKNRK

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=243, Percent_Identity=31.6872427983539, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13540533, Length=238, Percent_Identity=31.5126050420168, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI87082415, Length=296, Percent_Identity=43.2432432432432, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1786463, Length=282, Percent_Identity=42.1985815602837, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1788823, Length=277, Percent_Identity=31.0469314079422, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789620, Length=213, Percent_Identity=27.6995305164319, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: NA

Molecular weight: Translated: 35860; Mature: 35729

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACKWKGIIPPVVTLFDEKRGFDWEANYFLADYLIQQGVHGLLYMGSTGEFSSLTSEERK
CCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
VFAERMVRYVDGRVPVLIGTGSTSLKETIYLSQHAESIGASGVLVVNPFYWKYTDRQLYD
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEEECCHHHHH
YYTSVAKSIRIPLLIYNIPLLTGQDLSPDLVLRLAVEHENIVGIKDTTEKLGHIRQLIRI
HHHHHHHHHCCCEEEEECCEECCCCCCHHHEEEEEECCCCEECCCHHHHHHHHHHHHHHH
KEQREDFAVFAAFDDLLLPSLQMGAAGAINGTAVFLPELSVQLFESFHAQQYEETLKANE
HHHHHHHEEEEHHHHHHCCCHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
SILKLMAIYELSQPLYIAIKEAVHQLILGRHTALRPPVKECDELEDRIRIFLNKNNIQSY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEECCCCHHHH
REARNRLVFPKNRK
HHHHCCCCCCCCCC
>Mature Secondary Structure 
ACKWKGIIPPVVTLFDEKRGFDWEANYFLADYLIQQGVHGLLYMGSTGEFSSLTSEERK
CCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
VFAERMVRYVDGRVPVLIGTGSTSLKETIYLSQHAESIGASGVLVVNPFYWKYTDRQLYD
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEEECCHHHHH
YYTSVAKSIRIPLLIYNIPLLTGQDLSPDLVLRLAVEHENIVGIKDTTEKLGHIRQLIRI
HHHHHHHHHCCCEEEEECCEECCCCCCHHHEEEEEECCCCEECCCHHHHHHHHHHHHHHH
KEQREDFAVFAAFDDLLLPSLQMGAAGAINGTAVFLPELSVQLFESFHAQQYEETLKANE
HHHHHHHEEEEHHHHHHCCCHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
SILKLMAIYELSQPLYIAIKEAVHQLILGRHTALRPPVKECDELEDRIRIFLNKNNIQSY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEECCCCHHHH
REARNRLVFPKNRK
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]